Premo v. Martin

Published in cooperation with the American Bar Association Section of Dispute Resolutio

Quasirandomness in hypergraphs

An $n$-vertex graph $G$ of edge density $p$ is considered to be quasirandom if it shares several important properties with the random graph $G(n,p)$. A well-known theorem of Chung, Graham and Wilson states that many such `typical' properties are asymptotically equivalent and, thus, a graph $G$ possessing one such property automatically satisfies the others. In recent years, work in this area has focused on uncovering more quasirandom graph properties and on extending the known results to other discrete structures. In the context of hypergraphs, however, one may consider several different notions of quasirandomness. A complete description of these notions has been provided recently by Towsner, who proved several central equivalences using an analytic framework. We give short and purely combinatorial proofs of the main equivalences in Towsner's result.Comment: 19 page

Geostatistical analysis of an experimental stratigraphy

[1] A high-resolution stratigraphic image of a flume-generated deposit was scaled up to sedimentary basin dimensions where a natural log hydraulic conductivity (ln( K)) was assigned to each pixel on the basis of gray scale and conductivity end-members. The synthetic ln( K) map has mean, variance, and frequency distributions that are comparable to a natural alluvial fan deposit. A geostatistical analysis was conducted on selected regions of this map containing fluvial, fluvial/ floodplain, shoreline, turbidite, and deepwater sedimentary facies. Experimental ln(K) variograms were computed along the major and minor statistical axes and horizontal and vertical coordinate axes. Exponential and power law variogram models were fit to obtain an integral scale and Hausdorff measure, respectively. We conclude that the shape of the experimental variogram depends on the problem size in relation to the size of the local-scale heterogeneity. At a given problem scale, multilevel correlation structure is a result of constructing variogram with data pairs of mixed facies types. In multiscale sedimentary systems, stationary correlation structure may occur at separate scales, each corresponding to a particular hierarchy; the integral scale fitted thus becomes dependent on the problem size. The Hausdorff measure obtained has a range comparable to natural geological deposits. It increases from nonstratified to stratified deposits with an approximate cutoff of 0.15. It also increases as the number of facies incorporated in a problem increases. This implies that fractal characteristic of sedimentary rocks is both depositional process - dependent and problem-scale-dependent

Effects of butyltin exposures on MAP kinase-dependent transcription regulators in human natural killer cells

Natural killer (NK) cells are a major immune defense mechanism against cancer development and viral infection. The butyltins (BTs), tributyltin (TBT) and dibutyltin (DBT), have been widely used in industrial and other applications and significantly contaminate the environment. Both TBT and DBT have been detected in human blood. These compounds inhibit the lytic and binding function of human NK cells and thus could increase the incidence of cancer and viral infections. Butyltin (BT)-induced loss of NK function is accompanied by activation of mitogen activated protein kinases (MAPKs) and decreases in expression of cell-surface and cytolytic proteins. MAPKs activate components of the transcription regulator AP-1 and activate the transcription regulator Elk-1. Based on the fact that BTs activate MAPKs and alter protein expression, the current study examined the effect of BT exposures on the levels and phosphorylation states of the components of AP-1 and the phosphorylation state of Elk-1. Exposure to 300 nM TBT for 10 min increased the phosphorylation of c-Jun in NK cells. One hour exposures to 300 nM and 200 nM TBT increased the phosphorylation and overall level of c-Jun. During a 300 nM treatment with TBT for 1 h the binding activity of AP-1 was significantly decreased. There were no significant alterations of AP-1 components or of Elk-1 with DBT exposures. Thus, it appears that TBT-induced alterations on phosphorylation, total levels, and binding activity of c-Jun might contribute to, but are not fully responsible for, TBT-induced alterations of NK protein expression

Sistema de prevenção e combate a incêndios florestais no município de Campinas-SP.

A atividade agropecuária foi a grande responsável pela erradicação da cobertura florestal do Estado de São Paulo. Atualmente, uma das maiores ameaças aos remanescentes florestais é o risco de incêndios. Em Campinas-SP, a evolução do uso das terras acompanhou esta dinâmica. Hoje, esses remanescentes recobrem 2233 ha do Município, representando 2,8% da sua área total, distribuídos em 114 florestas que variam de 1 a 230 ha. Nos últimos 20 anos, a cobertura florestal se manteve estabilizada. São raríssimos os casos atuais de desmatamento, devido ao interesse dos proprietários em preservar essas áreas. Todavia, essas manchas isoladas de matas mesófilas não estão isentas à ocorrência de incêndios. eles destroem a vegetação, determinam uma nova fitodinâmica e levam, em geral, a uma regressão do potencial biológico dessas unidades, incluindo os povoamentos faunísticos. Entre as causas mais frequentes de incêndios estão as queimadas agrícolas em áreas vizinhas, a ação de piromaníacos, o comportamento irresponsável de transeuntes e a realização de cultos religiosos. Este trabalho inventariou todos os remanescentes florestais de Campinas-SP e elaborou um sistema de prevenção e combate a incêndios. Os resultados também estão disponíveis na Internet

Community Knowledge, Perceptions, and Practices Associated with Urogenital Schistosomiasis among School-Aged Children in Zanzibar, United Republic of Tanzania

Background: On the Zanzibar islands, United Republic of Tanzania, elimination of urogenital schistosomiasis is strived for in the coming years. This qualitative study aimed to better understand community knowledge, perceptions, and practices associated with schistosomiasis among school-aged children on Unguja and Pemba islands, in order to inform the development of behavior change interventions contributing to eliminate urogenital schistosomiasis. Methodology: In 2011, we conducted 35 children’s discussion groups, 41 in-depth interviews with parents and teachers, and 5 focus group discussions with community members in Zanzibar. Using a modified-grounded theory approach, we transcribed and coded the narrative data followed by thematic analysis of the emergent themes. Principal Findings: Urogenital schistosomiasis is a common experience among children in Zanzibar and typically considered a boys’ disease. Children engage in multiple high-risk behaviors for acquiring schistosomiasis because of poor knowledge on disease transmission, lack of understanding on severity of disease-associated consequences, and lack of alternative options for water related activities of daily living and recreational play. Local primary school teachers had little to no training about the disease and no teaching tools or materials for students. Conclusions/Significance: Conducting activities in open natural freshwater contaminated by S. haematobium larvae compromises the health of school-aged children in Zanzibar. The perception of urogenital schistosomiasis as a minor illness rather than a serious threat to a child’s well-being contributes to the spread of disease. Understanding community perceptions of disease along with the barriers and facilitators to risk reduction behaviors among children can inform health promotion activities, campaigns, and programs for the prevention, control, and elimination of urogenital schistosomiasis in Zanzibar

Combat and Warfare in the Early Paleolithic and Medically Unexplained Musculo-Facial Pain in the 21st Century War Veterns and Active-Duty Military Personnel

In a series of recent articles, we suggest that family dentists, military dentists and psychiatrists with expertise in posttraumatic stress disorder (especially in the Veterans Health Administration) are likely to see an increased number of patients with symptomatic jaw-clenching and early stages of tooth- grinding (Bracha et al., 2005). Returning warfighters and other returnees from military deployment may be especially at risk for high rates of clenching- induced masticatory muscle disorders at early stages of incisor grinding. The literature we have recently reviewed strongly supports the conclusion that clenching and grinding may primarily be a manifestation of experiencing extreme fear or severe chronic distress (respectively). We have recently reviewed the clinical and paleoanthropological literature and have noted that ancestral warfare and ancestral combat, in the early Paleolithic Environment of Evolutionary Adaptedness (EEA) may be a neglected factor explaining the conservation of the archaic trait of bite-muscle strengthening. We have hypothesized that among ancestral warriors, jaw clenching may have rapidly strengthened the two primary muscles involved in biting, the masseter muscles and the much larger temporalis muscles. The strengthening of these muscles may have served the purpose of enabling a stronger, deeper, and therefore more lethal, defensive bite for early Paleolithic humans. The neuroevolutionary perspective presented here may be novel to many dentists. However, it may be useful in patient education and in preventing progression from jaw-clenching to chronic facial pain