The Impact of Job Motivation and Non-Clinical Depression on Job Burnout during the COVID-19 Pandemic

The COVID-19 pandemic has brought significant distress to many individuals and caused substantial changes in their lives. Anecdotal and statistical evidence indicates decreased job motivation and significant job burnout in most recent years. Based on existing job burnout literature, the current study attempts to expand our understanding of the influence of job motivation on job burnout in relation to depression during the COVID-19 pandemic. Specifically, different types of job motivation compared to one another to examine their effects on two dimensions of job burnout: exhaustion and disengagement. In addition, non-clinical depression served as a moderator between motivation and job burnout. Results showed higher extrinsic motivation predicting higher burnout in general, but identified motivation was not a significant predictor of burnout. As expected, higher intrinsic motivation predicted lower job burnout. Finally, non-clinical depression moderated the influence of intrinsic motivation on job disengagement but not on job exhaustion

THE LABOUR MARKET AND THE SOCIAL SECURITY SYSTEMS IN THE CONTEXT OF ECONOMIC CRISIS

The globalization phenomenon and the creation of an economically and structurally strong Europe could not last forever. Knowing the economic phenomena’ cyclicity, the following question arises: Which will be the starting point of a new global crisis? Identifying the causes and culprits upon which the international committees and economic and political analysts focus on, we briefly deal with them in this article, because it is essential to concentrate on the measures and the crisis impact over social security. The goal of this article is to illustrate the crisis impact over the social security and labour market fields, the measures took in this field in Europe, around the world and in Romania. We bring in a synoptic table of the causes, effects, measures taken and incurring tendencies. The labour market’s issues and the Social Security System’s difficulties can be solved by vigorous measures, of which the authors recommend the ones resulting from the comparative study realized on a group of European countries and from Romania’s economic tendencies. How will the new economy look like, which will the new world leaders be, these do not matter for the small and vulnerable economies. We conclude that intelligence and professional qualification should outrun over the measureless accumulation of wealth and properties, which in our opinion means that a global economic crisis has its purpose and that it was predictable.Social security, labour market, economic crisis, unemployment

Prediction Strategies for Leveraging Information of Associated Traits under Single- and Multi-Trait Approaches in Soybeans

The availability of molecular markers has revolutionized conventional ways to improve genotypes in plant and animal breeding through genome-based predictions. Several models and methods have been developed to leverage the genomic information in the prediction context to allow more efficient ways to screen and select superior genotypes. In plant breeding, usually, grain yield (yield) is the main trait to drive the selection of superior genotypes; however, in many cases, the information of associated traits is also routinely collected and it can potentially be used to enhance the selection. In this research, we considered different prediction strategies to leverage the information of the associated traits ([AT]; full: all traits observed for the same genotype; and partial: some traits observed for the same genotype) under an alternative single-trait model and the multi-trait approach. The alternative single-trait model included the information of the AT for yield prediction via the phenotypic covariances while the multi-trait model jointly analyzed all the traits. The performance of these strategies was assessed using the marker and phenotypic information from the Soybean Nested Association Mapping (SoyNAM) project observed in Nebraska in 2012. The results showed that the alternative single-trait strategy, which combines the marker and the information of the AT, outperforms the multi-trait model by around 12% and the conventional single-trait strategy (baseline) by 25%. When no information on the AT was available for those genotypes in the testing sets, the multi-trait model reduced the baseline results by around 6%. For the cases where genotypes were partially observed (i.e., some traits observed but not others for the same genotype), the multi-trait strategy showed improvements of around 6% for yield and between 2% to 9% for the other traits. Hence, when yield drives the selection of superior genotypes, the single-trait and multi-trait genomic prediction will achieve significant improvements when some genotypes have been fully or partially tested, with the alternative single-trait model delivering the best results. These results provide empirical evidence of the usefulness of the AT for improving the predictive ability of prediction models for breeding applications

PENGEMBANGAN E-MODUL INTERAKTIF MENGGUNAKAN MICROSOFT OFFICE SWAY UNTUK MENINGKATKAN PEMAHAMAN KONSEP PESERTA DIDIK

ABSTRAK Penelitian ini bertujuan untuk mengembangkan e-modul interaktif menggunakan microsoft office sway yang bertujuan mengetahui peningkatan pemahaman konsep peserta didik sebelum dan sesudah penggunaanya. 1) E-modul interaktif menggunakan microsoft office sway dikembangkan dengan cara menggunakan model ADDIE (Analysis, Design, Development, Implementation and Evaluation).2) Kelayakan e-modul interaktif menggunakan microsoft office sway dinyatakan sangat layak digunakan dengan skor rata-rata dari ahli materi sebesar 85% dengan kriteria sangat layak dan diperoleh skor rata-rata oleh ahli media sebesar 82% dengan kriteria sangat layak. 3) Respon pendidik terhadap e-modul interaktif menggunakan microsoft office sway diperoleh hasil sangat menarik dengan skor rata-rata 89% dan sangat menarik bagi peserta didik dengan skor rata- rata 89,20%. 4)E-modul interaktif menggunakan microsoft office sway dinyatakan dapat membantu meningkatkan pemahaman konsep peserta didik dengan perbandingan hasil dari pretest dan posttest dengan perhitungan N-Gain mendapatkan nilai 0,82 dengan kriteria tinggi. Berdasarkan penelitian yang dilakukan oleh penulis dapat disimpulkan bahwa bahan ajar E-Modul interaktif menggunakan Microsoft Office Sway sangat layak dan menarik serta mampu meningkatkan pemahaman konsep peserta didik. Kata Kunci: Microsoft Office Sway, E-modul Interaktif, Pemahaman Konsep iv ABSTRACT This study aims to develop interactive e-modules using Microsoft Office Sway which aims to increase students' understanding of concepts before and after their use. 1) Products are developed using the ADDIE model (Analysis, Design, Development, Implementation and Evaluation). 2) Feasibility of interactive e�modules using microsoft office sway is stated to be very feasible to use with an average score from material experts of 85% with very criteria feasible and obtained an average score by media experts of 82% with very feasible criteria. 3) Educators' response to interactive e-modules using Microsoft Office Sway obtained very interesting results with an average score of 89% and very interesting for students with an average score of 89.20%. 4) Interactive e-modules using Microsoft Office Sway are stated to be able to help improve students' understanding of concepts by comparing the results of the pretest and posttest with the N-Gain calculation getting a score of 0.82 with high criteria. Based on the research conducted by the author, it can be concluded that interactive E-Module teaching materials using Microsoft Office Sway are very feasible and interesting and are able to improve students' understanding of concepts. Keywords: Microsoft Office Sway, Interactive E-module, Concept Understandin

Iniversities Networks and Academic Cooperation

The field of education, and especially that of higher education, is related directly to market needs as well as to social and political processes. In Europe, nowadays, this field is found itself in a prediod of transition with respect to both, its organizational structure and the establishment of its objectives. Such a transitional period is not independent that occurs in an environment of national diversities. Under these circumstances there are two fundamental principles upon which a modern university is based. The first includes the formation of a more flexible framework that allows development according to international social and economic conditions and the continiously expanding globalization the latter being a highly controversial concept that has been interpreted in various contradicting ways. The second, includes the perspective of establishing a common framework with the terms and conditions that influence formation and development of higher education as a whole. In other words a modern university takes two attributes into account: flexibility -which sounds a more or less straight forward concept; and cooperation in the sense analyzed below.

Measurement based investigation of cooperative relaying

Abstract — In this paper we present measurements that involve two access points (APs) and two user terminals, each of which is equipped with 4 antennas, in an indoor office environment. The data allow for the simultaneous characterization of the multiple input-multiple output (MIMO) links from the APs to the user terminals and between the user terminals, and are, to the best of our knowledge, the first of their kind. We show that the links between user terminals are impaired by body shadowing, and have therefore much lower gains than the direct links to the APs. Moreover we investigate the statistics of the links, and their correlation. Based on these measurements, we investigate the performance of cooperative relaying in terms of rate improvement (for this analysis the data from only one AP are used). We show that a significant rate improvement can be achieved if the relaying node is free to set the power level at which it transmits, and if it is free to select which of its antennas is used to perform the relaying. I

Promene hormonskih i lipidnih parametara u dece sa hipotiroidizmom; uticaj bolesti i supstitucione terapije

Clinical signs of thyroid gland hormones deficiency appear at different ages in infants with different concentrations of hormones. They depend on causes which had caused the hypothyroid degree of subsequents. Concentrations of hormones parameters: tT3, tT4, TSH, fT3, fT4, TBG and Tg (fluoroimmunoassay, DELFIA) and lipid parameters: total cholesterol (Chol), triglycerides (TRG), high density lipoprotein, (HDL-chol) and density lipoprotein, (LDLchol) were determined in order to establish changes that appear under the influence of the disease and replacement therapy in infants with hypothyroidism. In order to establish the influence of infant’s age on a determined parameter, all parameters where determined in the sample of healthy infants. A group of healthy infants (N=100) aged one mounth to 18 years, was devided in 5 age subgroups. The group of patients was devided into the same age groups as healthy group of the moment of diagnosis (N=56). Metabolic condition of an infant was established according to found by ANOVA test according to Tudey Snedecor method for the following parameters; T3 (d=0.35 p lt 0.001), fT3 (d=1.63 p lt 0.001) fT4 (d=2.59 p lt 0.001), TSH (d=2.27 p lt 0.001), TBG (d=90.82 p lt 0.001), Tg (d=4.59 p lt 0.02), Cho. (d=0.48 p lt 0.001) and LDL-chol. (d=0.51 p lt 0.001). These findings must be taken into account when the influence of replacement therapy on the observed parameters concentration changes is interpreted. The average concentration values were compared by Student’s t-test in infant before replacement therapy with that of the control subgroup of infants of the same age in order to evaluate the influence on values of the examined parameters. The average concentration values in infants after the replecement therapy were compared that before the replacement therapy as well as the control group, findings in order to the influence on the examined parameters. We observed significant changes hormone parameters in all agesubgroups under hypothyroid condition and return to control levels, except for T4 where the values were significantly higher in all age groups (p lt 0.05) in comparison to the control group. As for lipids, we found significantly higher values in all age subgroups for chol (p lt 0.01) and LDL-chol (p lt 0.001); they did not differ from that in control group after the replacement therapy. Patients were classified at the moment of clinical examination into the following categories: normometabolic (NM) and hypometabolic (HM). They were compared by Student’s T-test of different pairs with the condition before the replacement therapy. The percentage share in the change of TRG concentrations (p lt 0.02), LDL-chol (p lt 0.025) and T3 (p lt 0.001) was significantly different between NM and HM, and the long-lasting replacement therapy caused significant individual differences in Chol concentrations (NM ’ 37.90% p lt 0.001, HM ’ 15.14% p lt 0.001), HDL-chol (NM ’ 7.81% p lt 0.001, HM ’ 12.05% p lt 0.001), LDL-chol (NM ’ 50.15% P lt 0.001 HM 20.03 p lt 0.01) and T3 (NM ’ 105.04% p lt 0.001, HM 32.18% p>0.005). We conclude that hypothyroidism caused significant hormonal and metabolic changes in infants; however there is no clinical and laboratory index regarding the results of replacement therapy; this is the reason why the patient’s condition must be evaluated individually.Zavisno od uzroka koji su doveli do hipotiroidnog stanja kod deteta (dishormonogeneza, hipoplazija, ektopija, atireoza), a time i težine poremećaja, klinički znaci deficita hormona štitne žlezde ispoljavaju se u različitom uzrastu deteta, s različitim koncentracijama ispitivanih hormona. U cilju utvrđivanja promena nastalih pod uticajem bolesti i supstitucione terapije kod dece s hipotiroidizmom određene su koncentracije hormonskih parametara: tT3, tT4, TSH, fT3, fT4, TBG i Tg (fluoroimunotest DELFIA), kao i lipidnih: ukupni holesterol, trigliceridi, HDL-holesterol i LDL-holesterol. Za utvrđivanje uticaja starosti deteta na ispitivani parametar isti su obrađeni u uzorku zdrave dece. Grupa zdrave dece N=100 uzrasta od 1 meseca do 18 godina podeljena je u 5 starosnih podgrupa. Posebnu grupu sačinjava uzorak uzet iz pupčane vrpce, zdravo rođene dece. Grupa obolele dece je podeljena po istim starosnim grupama kao i zdrava grupa i to: u momentu otkrivanja bolesti (N=58) i u momentu kasnijeg pregleda, posle dugovremene supstitucione terapije sa L-T4 (N=56). Metaboličko stanje deteta utvrđeno je po kriterijumu specifičnih klinički znakova i simptoma. ANOVA testom po metodi Tudey Snedecor-a utvrđena je statistički značajna razlika između starosnih podgrupa za sledeće parametre: T3 (d=0,35 p lt 0,001), fT3 (d=1,63 p lt 0,001) fT4 (d=2,59 p lt 0,001), TSH (d=2,27 p lt 0,001), TBG (d=90,82 p lt 0,001), Tg (d=4,59 p lt 0,02), holesterola (d=0,48 p lt 0,001) i LDL-holesterola (d=0,51 p lt 0,001), što se mora uzeti u obzir kod tumačenja uticaja supstitucione terapije na izmenu koncentracija posmatranih parametara. Koncentracije svih hormonskih parametara u uzorku pupčane vrpce se razlikuje od koncentracija u ostalim starosnim grupama dece, osim za T4. Da bi se procenio uticaj bolesti na vrednosti ispitivanih parametara, upoređene su vrednosti srednjih koncentracija Studentovim T-testom podgrupa dece pre supstitucije sa kontrolnim grupama dece iste starosne dobi. Za procenu uticaja supstitucije na ispitivane parametre upoređene su srednje koncentracije ispitivanih parametara, grupe dece posle supstitucije sa grupom dece pre supstitucije kao i sa kontrolnom grupom. Za posmatrane hormonske parametre imamo značajne izmene u svim starosnim podgrupama, sa nastankom hipotiroidnog stanja i vraćanje na nivo vrednosti kontrolne grupe sem za T4 kada su vrednosti značajno više u svim starosnim grupama (p lt 0,05) u odnosu na kontrolu. Kod lipida značajno veće vrednosti nađene su u svim starosnim podgrupama za holesterol (p lt 0,01) i LDL-holesterol (p lt 0,001) koje se ne razlikuju od kontrolne grupe posle supstitucione terapije. Pacijente su u momentu kliničkog pregleda razvrstali u kategorije normometabolični (NM) i hipometabolični (HM) i upoređeni Studentovim T-testom razlike parova sa sopstvenim stanjem pre supstitucione terapije. Procentualni udeo u izmeni koncentracija triglicerida (p lt 0,02) LDL-holesterola (p lt 0,025) i T3 (p lt 0,001) je značajno različit između NM I HM, a dugogodišnja supstituciona terapija dovodi do značajnih interindividualnih razlika u koncentracijama holesterola (NM ’ 37,90% p lt 0.001, HM - 15,14% p lt 0,001) HDL-holesterola (NM - 7,81% p lt 0.001, HM - 12,0,05% p lt 0.001), LDL-holesterola (NM - 50,15% P lt 0,001 HM 20,03 p lt 0,01) i T3 (NM 105,04% p lt 0,001, HM - 32,18% p>0,005). Zaključujemo da hipotiroidizam dovodi do značajnih hormonskih i metaboličkih promena kod obolele dece, ali ne postoji generalni klinički i laboratorijski indeks postignutog rezultata supstitucione terapije, te zbog toga se individualno procenjuje stanje bolesnika

Familias con hijos abanderados

Admitiendo como primer paso que la escuela en que nos desempeñamos forma parte de las estrategias de reproducción y legitimación social de las diferencias de clase, nos surgieron interrogantes cuando observamos en nuestra práctica docente, a aquellos alumnos que se distinguían de los otros, en lo referente a sus logros académicos, lo cual los convertía en los abanderados del establecimiento educacional al cual asistían. Además, nos fue posible constatar que los hermanos de esos alumnos, por lo general, también sobresalían por las mismas características. En primer pudimos observar que existen familias, las cuales, partiendo de un capital cultural similar a las otras, logran mejores resultados. Ello nos llevó a pensar en las familias de estos alumnos y a fijar las características que deberían tener las relaciones entre sus integrantes para que los hijos fueran abanderados. A medida que avanzamos en el motivo de nuestra búsqueda, fuimos encontrando algunas respuestas. Compartimos junto a padres y madres espacios de diálogo y reflexión acerca de las condiciones de educación y crianza de sus hijos. Comparamos los datos que cada uno logró extraer de esos encuentros, y obtuvimos los aspectos particulares. Asimismo, observamos la importancia del acompañamiento y apoyo de los padres en el aprendizaje escolar de sus hijos, el tipo de liderazgo familiar, y el impacto de la transmisión de valoraciones positivas sobre la escuelaEje: Reflexiones educación Siglo XXIRed de Universidades con Carreras en Informática (RedUNCI

A distinct four-value blood signature of pyrexia under combination therapy of malignant melanoma with dabrafenib and trametinib evidenced by an algorithm-defined pyrexia score

Pyrexia is a frequent adverse event of BRAF/MEK-inhibitor combination therapy in patients with metastasized malignant melanoma (MM). The study’s objective was to identify laboratory changes which might correlate with the appearance of pyrexia. Initially, data of 38 MM patients treated with dabrafenib plus trametinib, of which 14 patients developed pyrexia, were analysed retrospectively. Graphical visualization of time series of laboratory values suggested that a rise in C-reactive-protein, in parallel with a fall of leukocytes and thrombocytes, were indicative of pyrexia. Additionally, statistical analysis showed a significant correlation between lactate dehydrogenase (LDH) and pyrexia. An algorithm based on these observations was designed using a deductive and heuristic approach in order to calculate a pyrexia score (PS) for each laboratory assessment in treated patients. A second independent data set of 28 MM patients, 8 with pyrexia, was used for the validation of the algorithm. PS based on the four parameters CRP, LDH, leukocyte and thrombocyte numbers, were statistically significantly higher in pyrexia patients, differentiated between groups (F = 20.8; p = <0.0001) and showed a significant predictive value for the diagnosis of pyrexia (F = 6.24; p = 0.013). We provide first evidence that pyrexia in patients treated with BRAF/MEK-blockade can be identified by an algorithm that calculates a score