365 research outputs found
Treelicious: a System for Semantically Navigating Tagged Web Pages
Collaborative tagging has emerged as a popular and effective method for
organizing and describing pages on the Web. We present Treelicious, a system
that allows hierarchical navigation of tagged web pages. Our system enriches
the navigational capabilities of standard tagging systems, which typically
exploit only popularity and co-occurrence data. We describe a prototype that
leverages the Wikipedia category structure to allow a user to semantically
navigate pages from the Delicious social bookmarking service. In our system a
user can perform an ordinary keyword search and browse relevant pages but is
also given the ability to broaden the search to more general topics and narrow
it to more specific topics. We show that Treelicious indeed provides an
intuitive framework that allows for improved and effective discovery of
knowledge.Comment: 6 pages, 3 figure
Amgen Material Handling
Amgen is a world leading pharmaceutical company that specializes in biotechnology which develops intravenous or injectable biologic medicines. With an outstanding reputation in the field of safety, quality assurance, superior scientific innovation, and continuous improvement in all aspects, Amgen’s goal is to serve patients cutting edge medications available in today’s market. With this outlook on innovation, Amgen is currently looking into a material handling solution for movement of material between its storage facilities to an IOS9 cleanliness standard laboratory. Such movement includes passing through an airlock which requires the drums containing necessary chemicals for biotechnological production to be cleaned and remain in wet-lock with a specified bleach solution. This process is currently in question since these drums are being handled manually by workers at the risk of injury. With barrels that range from twenty-two to two hundred fifty pounds, great risk is associated with repetitive movement by workers tilting and cleaning these drums, and injury prevention is the main motive for the process change. This manual movement of drums lacks sufficient ergonomics while subjecting workers to injury, and a change must be implemented. A close look will be taken at the current process, and a mechanism will be designed to assist the worker during the new improved moving and cleaning process. Factors including safety, ergonomics, cleanability, timing, and cost will be considered in respective importance. Research on current patents, literature, and competitors’ solutions to material handling will be considered in the final design of a mechanism. Devices that were ultimately considered and compared include: electric motor-driven barrel lifters and turners, manual lifting assist devices, and automated systems, all of which would be customized to the company’s preference of cleanability, ease of use, and size and power limitations addressed by Amgen
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Self-management support for chronic disease in primary care: frequency of patient self-management problems and patient reported priorities, and alignment with ultimate behavior goal selection.
BackgroundTo enable delivery of high quality patient-centered care, as well as to allow primary care health systems to allocate appropriate resources that align with patients' identified self-management problems (SM-Problems) and priorities (SM-Priorities), a practical, systematic method for assessing self-management needs and priorities is needed. In the current report, we present patient reported data generated from Connection to Health (CTH), to identify the frequency of patients' reported SM-Problems and SM-Priorities; and examine the degree of alignment between patient SM-Priorities and the ultimate Patient-Healthcare team member selected Behavioral Goal.MethodsCTH, an electronic self-management support system, was embedded into the flow of existing primary care visits in 25 primary care clinics and was used to assess patient-reported SM-Problems across 12 areas, patient identified SM-Priorities, and guide the selection of a Patient-Healthcare team member selected Behavioral Goal. SM-Problems included: BMI, diet (fruits and vegetables, salt, fat, sugar sweetened beverages), physical activity, missed medications, tobacco and alcohol use, health-related distress, general life stress, and depression symptoms. Descriptive analyses documented SM-Problems and SM-Priorities, and alignment between SM-Priorities and Goal Selection, followed by mixed models adjusting for clinic.Results446 participants with ≥ one chronic diseases (mean age 55.4 ± 12.6; 58.5% female) participated. On average, participants reported experiencing challenges in 7 out of the 12 SM-Problems areas; with the most frequent problems including: BMI, aspects of diet, and physical activity. Patient SM-Priorities were variable across the self-management areas. Patient- Healthcare team member Goal selection aligned well with patient SM-Priorities when patients prioritized weight loss or physical activity, but not in other self-management areas.ConclusionParticipants reported experiencing multiple SM-Problems. While patients show great variability in their SM-Priorities, the resulting action plan goals that patients create with their healthcare team member show a lack of diversity, with a disproportionate focus on weight loss and physical activity with missed opportunities for using goal setting to create targeted patient-centered plans focused in other SM-Priority areas. Aggregated results can assist with the identification of high frequency patient SM-Problems and SM-Priority areas, and in turn inform resource allocation to meet patient needs.Trial registrationClinicalTrials.gov ID: NCT01945918
ORS Responsive Manufacturing 6U Spacecraft
The Operationally Responsive Space Office is developing a small satellite capability and small satellite design specifically for advanced manufacturing and assembly methods for a semi-automated assembly and test facility. Designing a small satellite to be assembled and tested with this novel and innovative approach enables reduced costs, schedule, and risk. This presentation will discuss the implementation, unique design features, lessons learned, and challenges associated with developing for this new rapid-assembly capability as well as the unique benefits and challenges of assembly and test using automated, robotic systems. The presentation will also include discussions of the role that design-for-manufacturing, modular open system architecture, componentized subsystems, and standardized interfaces each play in developing the spacecraft. Assembly processes, ground support interfaces, and other assembly, integration and test needs will also be discussed
A Survey of Moratorium Efforts and a Walk Through the Process of Enacting a Moratorium
Evaluation of Performance and Costs of Two Heifer Development Systems
Early weaned (EW) heifers must be developed for a longer period of time usually resulting in increased development costs. Developing EW heifers on native range may reduce these costs. Dried distillers grains plus solubles (DDGS) offers protein and energy that compliment native forages for developing heifers. The objective of this study was to evaluate the performance and costs of two heifer development systems in northwest South Dakota. Sixty-five nulliparous crossbred beef heifers were randomly allotted to one of two systems: 1) heifers (n=33) weaned at 132 d of age (461 lb) and developed on range with a DDGS supplement (1.8 to 6.4 lb/hd/d) from Sept. 25 to May 18 (Range); 2) heifers (n=32) weaned at 218 days of age (605 lb) and developed in a drylot with grass hay and a conventional supplement (2.6 to 3.6 lb/hd/d) from Dec. 2 to May 18 (Normal). Supplement levels were established to result in both groups of heifers reaching 65% of mature weight at breeding (863 lb). All heifers were managed similarly after May 18. Heifers were synchronized with a shot of PGF2α and bred natural service beginning June 14. As necessary for target weights to be reached, ADG through the feeding period was greater (P \u3c 0.05) for Range (1.68 lb/d) than (Normal 1.34 lb/d). Range heifers tended (P = 0.12) to be heavier on May 18 (859 and 830 lb, respectively) and were heavier (P \u3c 0.05) at breeding (915 and 834 lb, respectively). Weight differences in May were a result of higher than expected gains by the Range heifers in the spring. From May 18 to June 14, Range heifers gained more (P \u3c 0.05) than Normal (2.07 and 0.32 lb/d, respectively). Synchronized conception and overall pregnancy rates were similar (P \u3e 0.25) between the Range and Normal heifers (58% vs. 50% and 91% vs. 88%, respectively). Supplement and forage costs for the Range system was similar (117/hd). Range development provides an alternative method for developing early-weaned heifers that reduces daily costs
Eyetracking-enhanced VEP for nystagmus
Visual evoked potentials (VEPs) are an important prognostic indicator of visual ability in patients with nystagmus. However, VEP testing requires stable fixation, which is impossible with nystagmus. Fixation instability reduces VEP amplitude, and VEP reliability is therefore low in this important patient group. We investigated whether VEP amplitude can be increased using an eye tracker by triggering acquisition only during slow periods of the waveform. Data were collected from 10 individuals with early-onset nystagmus. VEP was obtained under continuous (standard) acquisition, or triggered during periods of low eye velocity, as detected by an eye tracker. VEP amplitude was compared using Bonferroni corrected paired samples t-tests. VEP amplitude is significantly increased when triggered during low eye velocity (95% CI 1.42–6.83 µV, t(15) = 3.25, p = 0.0053). This study provides proof-of-concept that VEP amplitude (and therefore prognostic reliability) can be increased in patients with early onset nystagmus by connecting an eye tracker and triggering acquisition during periods of lower eye velocity
bMagazine 2020
bMagazine is part annual report and part showcase of people thinking bigger and thinking differently about what's possible in communities across the Bush Foundation's region of Minnesota, North Dakota, South Dakota and the 23 Native nations that share that geography
Be X-ray binaries in the SMC as indicators of mass transfer efficiency
Be X-ray binaries (BeXRBs) consist of rapidly rotating Be stars with neutron
star companions accreting from the circumstellar emission disk. We compare the
observed population of BeXRBs in the Small Magellanic Cloud with simulated
populations of BeXRB-like systems produced with the COMPAS population synthesis
code. We focus on the apparently higher minimal mass of Be stars in BeXRBs than
in the Be population at large. Assuming that BeXRBs experienced only
dynamically stable mass transfer, their mass distribution suggests that at
least 30% of the mass donated by the progenitor of the neutron star is
typically accreted by the B-star companion. We expect these results to affect
predictions for the population of double compact object mergers. A convolution
of the simulated BeXRB population with the star formation history of the Small
Magellanic Cloud shows that the excess of BeXRBs is most likely explained by
this galaxy's burst of star formation around 20--40 Myr ago
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