13 research outputs found
Biblijska aksiologija u jeziku
U diplomskome radu Библейская аксиология в языке (Biblijska aksiologija u jeziku)
govorili smo o biblizmima i drugim riječima biblijskog porijekla na način da smo uspoređivali
njihova prvotna značenja, vrijednosti i kontekst u kojem se pojavljuju u Svetome Pismu sa
značenjima u suvremenome ruskom jeziku.
Budući da smo se u prvome dijelu rada posvetili biblijskim frazemima, prvo smo
objasnili pojmove frazem i biblizam. Spomenuli smo također i povijesni razvitak biblizama u
ruskome jeziku koji je utjecao na njihov status u suvremenom jeziku. Uspoređujući
vrijednosti biblijskih frazema u Svetome Pismu s njihovim vrijednostima u današnjem
ruskome jeziku, ustvrdili smo da postoje frazemi koji imaju isto značnje danas, kao što su
imali i u Bibliji, zatim oni koji imaju metaforičko značenje u oba slučaja, potom frazemi koji
su u Bibliji upotrijebljeni u izvornom značenju, dok su u suvremenom jeziku metafora, i na
kraju frazemi čija se značenja danas u potpunosti razlikuju od biblijskih izvora. Posebnu smo
pažnju posvetili upravo posljednjoj grupi, u koju ulaze sljedeći izrazi: злачное место; нищие
духом; Кто не со Мною, тот против Меня; кающаяся Магдалина; иерихонская труба;
бесплодная смоковница; чаша терпения переполнена (переполнилась); вложить персты
в язвы; быть в духе i Валаамова ослица. Ti su nam frazemi poslužili kao primjer potpune
promjene biblijskih značenja i vrijednosti u suvremenom jeziku.
U drugome dijelu rada objasnili smo pojam aksiologija i u kontekstu toga pojma
promatrali smo značenja i vrijednosti biblijskih riječi koje nisu biblizmi, ali se pojavljuju u
kontekstu kršćanske filozofije: лик, лицо, личина (маска); плоть, тело, душа, дух; ум,
разум, рассудок; целитель, врачь, лекарь. Pozivajući se na brojne autore i izvore,
obrazložili smo svaki od spomenutih pojmova zasebno te smo ih međusobno usporedili. Neke
od spomenutih riječi sačuvale su svoja prvotna značenja (лик, врачь, лекарь), neke su uz
svoja izvorna značenja s vremenom dobila nova (тело, душa, лицо, личина, дух, целитель),
a nekima su se vrijednosti promijenile, čak i izjednačile (ум, разум, рассудок). Takvi izrazi u
svome prvotnom izvoru – u Bibliji – imaju određenu težinu jer se koriste u kontekstu
transcedentnoga svijeta i duhovnoga života. Prema tome, i njihove su vrijednosti duboke,
osobito u kršćanskoj filozofiji i vjeroispovijesti. Također, riječi koje se danas smatraju
sinonimima u kršćanskoj se filozofiji jasno razlikuju. Kako vidimo u ovome radu, vrijednosti
većine spomenutih pojmova (лицо, тело, душа, дух, ум, разум, рассудок, целитель) bitno
su se izmijenile tijekom povijesti pa sve do danas
Sex difference and intra-operative tidal volume: Insights from the LAS VEGAS study
BACKGROUND: One key element of lung-protective ventilation is the use of a low tidal volume (VT). A sex difference in use of low tidal volume ventilation (LTVV) has been described in critically ill ICU patients.OBJECTIVES: The aim of this study was to determine whether a sex difference in use of LTVV also exists in operating room patients, and if present what factors drive this difference.DESIGN, PATIENTS AND SETTING: This is a posthoc analysis of LAS VEGAS, a 1-week worldwide observational study in adults requiring intra-operative ventilation during general anaesthesia for surgery in 146 hospitals in 29 countries.MAIN OUTCOME MEASURES: Women and men were compared with respect to use of LTVV, defined as VT of 8 ml kg-1 or less predicted bodyweight (PBW). A VT was deemed 'default' if the set VT was a round number. A mediation analysis assessed which factors may explain the sex difference in use of LTVV during intra-operative ventilation.RESULTS: This analysis includes 9864 patients, of whom 5425 (55%) were women. A default VT was often set, both in women and men; mode VT was 500 ml. Median [IQR] VT was higher in women than in men (8.6 [7.7 to 9.6] vs. 7.6 [6.8 to 8.4] ml kg-1 PBW, P < 0.001). Compared with men, women were twice as likely not to receive LTVV [68.8 vs. 36.0%; relative risk ratio 2.1 (95% CI 1.9 to 2.1), P < 0.001]. In the mediation analysis, patients' height and actual body weight (ABW) explained 81 and 18% of the sex difference in use of LTVV, respectively; it was not explained by the use of a default VT.CONCLUSION: In this worldwide cohort of patients receiving intra-operative ventilation during general anaesthesia for surgery, women received a higher VT than men during intra-operative ventilation. The risk for a female not to receive LTVV during surgery was double that of males. Height and ABW were the two mediators of the sex difference in use of LTVV.TRIAL REGISTRATION: The study was registered at Clinicaltrials.gov, NCT01601223
Tjelesno vježbanje i autizam
U ovome će radu biti prikazani postupci koji se primjenju u radu s djecom koja boluju od autizma, te osnovni postupci za provođenje tjelesnog vježbanja kod djece s autizmom. Autizam je razvojni poremećaj koji počinje u djetinjstvu i zahvaća gotovo sve psihičke funkcije, a traje cijeli život. Prilagođena tjelesna aktivnost veoma je bitna za djecu koja boluju od autizma. Veoma je bino što ranije prepoznati ovaj poremećaj da bi se što prije moglo krenuti u pravilnu rehabilitaciju ove djece. Odabrane metode rada utječu na pravilan rast i razvoj svih funkcija djeteta s autizmom. Tjelesno vježbanje je dio rehabilitacijskog postupka i veoma je bitno u cilju unaprjeđenja života svakog pojedinca. Svaki kineziolog i onaj tko će to tek postati mora biti svjestan ove odgovornosti, te mora biti educiran o metodama rada kod djece s autizmom. Tjelesno vježbanje pridonosi otklanjanju simptoma autizma i utječe pozitivno na djecu koja boluju od autizma. Svaki stručnjak u radu sa djecom s autizmom mora bit strpljiv, te poticati i pozitivno podupirati djecu. Što ranije integriramo dijete u zajednicu ono će bolje odgovoriti na zahtjeve koje ona postavlja. U radu s djecom s autizmom sudjeluju mnogi stručnjaci poput fizioterapeuta, kineziterapeuta, te liječnika, ali i roditelji, te svi oni koji se nalaze u blizini ove djece. Dijete s autizmom se ne smije isključivati iz zajednice, već ga treba podupirati i pružiti sve ono što mu je potrebno za svakodnevi život. Najčešće je okolina pod dojmom nedostaka, te tako procjenjuje djecu s autizmom. To je veoma pogrešno mišljenje jer mnoga djeca koja boluju od ovog poremećaja pokazuju izrazite sposobnosti u nekim područjima. Ono što je veoma bitno da se nikad ne odustaje od djece ove populacije jer nijedno dijete nebi smjelo biti zapostavljeno niti u kojem području.In this work will be presented procedures is applied in work with children suffering from autism, and basic procedures for the implementation of physical exercise in children with autism. Autism is a developmental disorder that begins in childhood and affects almost all psychic functions, and lasts for a lifetime. Adapted physical activity is very important for children suffering from autism. It is very important to recognize this disorder beforehand in order to initiate the proper rehabilitation of these children as soon as possible. Selected methods of work influence the proper growth and development of all functions of a child with autism. Physical exercise is part of the rehabilitation process and is very important in order to improve the life of each individual. Each physical education and one who is about to become must be aware of this responsibility, and must be educated about methods of work with children with autism. Physical exercise contributes to the elimination of autism symptoms and has a positive effect on children suffering from autism. Everyone in the work with children with autism needs to be patient and encourage and positively support the children. The earlier we integrate a child into the community will better respond to the demands she sets. Many experts such as physiotherapists, chemotherapists, doctors, and parents, and all those near these children are involved in the work with autistic children. A child with autism must not be excluded from the community, but should support and provide everything he needs for everyday life. Most commonly, the environment is under the impression of a disadvantage, and so estimates the children with autism. This is a very wrong opinion because many children suffering from this disorder show strong abilities in some areas. What is very important is that you never give up the children of this population because no child should be neglected in any area
Tjelesno vježbanje i autizam
U ovome će radu biti prikazani postupci koji se primjenju u radu s djecom koja boluju od autizma, te osnovni postupci za provođenje tjelesnog vježbanja kod djece s autizmom. Autizam je razvojni poremećaj koji počinje u djetinjstvu i zahvaća gotovo sve psihičke funkcije, a traje cijeli život. Prilagođena tjelesna aktivnost veoma je bitna za djecu koja boluju od autizma. Veoma je bino što ranije prepoznati ovaj poremećaj da bi se što prije moglo krenuti u pravilnu rehabilitaciju ove djece. Odabrane metode rada utječu na pravilan rast i razvoj svih funkcija djeteta s autizmom. Tjelesno vježbanje je dio rehabilitacijskog postupka i veoma je bitno u cilju unaprjeđenja života svakog pojedinca. Svaki kineziolog i onaj tko će to tek postati mora biti svjestan ove odgovornosti, te mora biti educiran o metodama rada kod djece s autizmom. Tjelesno vježbanje pridonosi otklanjanju simptoma autizma i utječe pozitivno na djecu koja boluju od autizma. Svaki stručnjak u radu sa djecom s autizmom mora bit strpljiv, te poticati i pozitivno podupirati djecu. Što ranije integriramo dijete u zajednicu ono će bolje odgovoriti na zahtjeve koje ona postavlja. U radu s djecom s autizmom sudjeluju mnogi stručnjaci poput fizioterapeuta, kineziterapeuta, te liječnika, ali i roditelji, te svi oni koji se nalaze u blizini ove djece. Dijete s autizmom se ne smije isključivati iz zajednice, već ga treba podupirati i pružiti sve ono što mu je potrebno za svakodnevi život. Najčešće je okolina pod dojmom nedostaka, te tako procjenjuje djecu s autizmom. To je veoma pogrešno mišljenje jer mnoga djeca koja boluju od ovog poremećaja pokazuju izrazite sposobnosti u nekim područjima. Ono što je veoma bitno da se nikad ne odustaje od djece ove populacije jer nijedno dijete nebi smjelo biti zapostavljeno niti u kojem području.In this work will be presented procedures is applied in work with children suffering from autism, and basic procedures for the implementation of physical exercise in children with autism. Autism is a developmental disorder that begins in childhood and affects almost all psychic functions, and lasts for a lifetime. Adapted physical activity is very important for children suffering from autism. It is very important to recognize this disorder beforehand in order to initiate the proper rehabilitation of these children as soon as possible. Selected methods of work influence the proper growth and development of all functions of a child with autism. Physical exercise is part of the rehabilitation process and is very important in order to improve the life of each individual. Each physical education and one who is about to become must be aware of this responsibility, and must be educated about methods of work with children with autism. Physical exercise contributes to the elimination of autism symptoms and has a positive effect on children suffering from autism. Everyone in the work with children with autism needs to be patient and encourage and positively support the children. The earlier we integrate a child into the community will better respond to the demands she sets. Many experts such as physiotherapists, chemotherapists, doctors, and parents, and all those near these children are involved in the work with autistic children. A child with autism must not be excluded from the community, but should support and provide everything he needs for everyday life. Most commonly, the environment is under the impression of a disadvantage, and so estimates the children with autism. This is a very wrong opinion because many children suffering from this disorder show strong abilities in some areas. What is very important is that you never give up the children of this population because no child should be neglected in any area
Tjelesno vježbanje i autizam
U ovome će radu biti prikazani postupci koji se primjenju u radu s djecom koja boluju od autizma, te osnovni postupci za provođenje tjelesnog vježbanja kod djece s autizmom. Autizam je razvojni poremećaj koji počinje u djetinjstvu i zahvaća gotovo sve psihičke funkcije, a traje cijeli život. Prilagođena tjelesna aktivnost veoma je bitna za djecu koja boluju od autizma. Veoma je bino što ranije prepoznati ovaj poremećaj da bi se što prije moglo krenuti u pravilnu rehabilitaciju ove djece. Odabrane metode rada utječu na pravilan rast i razvoj svih funkcija djeteta s autizmom. Tjelesno vježbanje je dio rehabilitacijskog postupka i veoma je bitno u cilju unaprjeđenja života svakog pojedinca. Svaki kineziolog i onaj tko će to tek postati mora biti svjestan ove odgovornosti, te mora biti educiran o metodama rada kod djece s autizmom. Tjelesno vježbanje pridonosi otklanjanju simptoma autizma i utječe pozitivno na djecu koja boluju od autizma. Svaki stručnjak u radu sa djecom s autizmom mora bit strpljiv, te poticati i pozitivno podupirati djecu. Što ranije integriramo dijete u zajednicu ono će bolje odgovoriti na zahtjeve koje ona postavlja. U radu s djecom s autizmom sudjeluju mnogi stručnjaci poput fizioterapeuta, kineziterapeuta, te liječnika, ali i roditelji, te svi oni koji se nalaze u blizini ove djece. Dijete s autizmom se ne smije isključivati iz zajednice, već ga treba podupirati i pružiti sve ono što mu je potrebno za svakodnevi život. Najčešće je okolina pod dojmom nedostaka, te tako procjenjuje djecu s autizmom. To je veoma pogrešno mišljenje jer mnoga djeca koja boluju od ovog poremećaja pokazuju izrazite sposobnosti u nekim područjima. Ono što je veoma bitno da se nikad ne odustaje od djece ove populacije jer nijedno dijete nebi smjelo biti zapostavljeno niti u kojem području.In this work will be presented procedures is applied in work with children suffering from autism, and basic procedures for the implementation of physical exercise in children with autism. Autism is a developmental disorder that begins in childhood and affects almost all psychic functions, and lasts for a lifetime. Adapted physical activity is very important for children suffering from autism. It is very important to recognize this disorder beforehand in order to initiate the proper rehabilitation of these children as soon as possible. Selected methods of work influence the proper growth and development of all functions of a child with autism. Physical exercise is part of the rehabilitation process and is very important in order to improve the life of each individual. Each physical education and one who is about to become must be aware of this responsibility, and must be educated about methods of work with children with autism. Physical exercise contributes to the elimination of autism symptoms and has a positive effect on children suffering from autism. Everyone in the work with children with autism needs to be patient and encourage and positively support the children. The earlier we integrate a child into the community will better respond to the demands she sets. Many experts such as physiotherapists, chemotherapists, doctors, and parents, and all those near these children are involved in the work with autistic children. A child with autism must not be excluded from the community, but should support and provide everything he needs for everyday life. Most commonly, the environment is under the impression of a disadvantage, and so estimates the children with autism. This is a very wrong opinion because many children suffering from this disorder show strong abilities in some areas. What is very important is that you never give up the children of this population because no child should be neglected in any area
Tâche d'apprentissage dans l'enseignement du français langue étrangère : niveau secondaire
U ovom diplomskome radu opisana je vrsta aktivnosti koja se u hrvatskoj terminologiji naziva zadatak. Njegov je ekvivalent u francuskom jeziku tâche (d'apprentissage / communicative). Takvu vrstu aktivnosti predložilo je Vijeće Europe unutar Zajedničkog europskog referentnog okvira za jezike 2001. godine. Zadatak može obuhvaćati razne vrste aktivnosti, od slušanja ili čitanja s razumijevanjem, preko pisanja i govorenja na stranome jeziku pa sve do aktivnosti vezanih za gramatiku, vokabular i kulturu. Brojne su definicije zadatka, kao i njegove podjele na manje jedinice. On može biti jednostavan ili složen, kao što može obuhvaćati više dimenzija i imati razne ciljeve. Mnogi autori kao jednu od najvažnijih karakteristika zadatka navode učenikovo prepoznavanje i razumijevanje cilja vježbe. Mi smo u ovome radu pokušali što detaljnije predstvaiti ovu vrstu nastavne aktivnosti. Počeli smo od konteksta u kojem su autori razvili njezin koncept i naveli smo nekoliko njezinih definicija i primjera. Objasnili smo zašto Vijeće Europe u Zajedničkom europskom referentnom okviru za jezike predlaže upravo ovu vrstu aktivnosti i koje su njezine prednosti i nedostaci. Razmotrili smo njezine dimenzije i tipologije. Na osnovi jedne od predloženih tipologija, prikazane u tablici koju je predložila É. Bérard, proučavali smo zadatke u prve četiri cjeline u udžbeniku francuskog jezika za srednju školu Alter Ego 2 (razina A2). Za vrste zadataka koji se najčešće pojavljuju u našem udžbeniku dali smo primjere. Pod pretpostavkom da bi većina vrsta zadataka trebala biti podjednako zastupljena u odabranom udžbeniku, prebrojali smo sve vrste i rezultate upisali u tablicu. Na temelju dobivenih rezultata, kvalitativnom analizom ustanovili smo koje se vrste zadataka pojavljuju češće, a koje su zastupljene u manjoj mjeri.Dans notre mémoire nous avons décrit la tâche d’apprentissage, promue par le Conseil de l’Europe dans le Cadre européen commun de référence pour les langues de l’année 2001. La tâche d’apprentissage comprend de différents types d’activités : la compréhension et la production orale et écrite, ainsi que les activités liées à la grammaire, au lexique ou à la culture. Nous connaissons de nombreuses définitions et plusieurs typologies de la tâche. Elle peut être simple ou complexe, elle peut comprendre les dimensions différentes et avoir de divers objectifs. L’apprenant devrait reconnaître et comprendre l’objectif de l’activité – c’est une des plus importantes caractéristiques de la tâche selon plusieurs auteurs. Dans notre mémoire nous avons essayé de présenter en détails ce type d’activité scolaire. Tout d’abord nous avons mentionné le contexte dans lequel les chercheurs ont abordé le concept de tâche et nous en avons donné quelques définitions et exemples. Nous avons essayé d’expliquer pourquoi le Conseil de l’Europe propose ce type d’activité en décrivant ses avantages et ses inconvénients. Nous avons aussi étudié ses dimensions et typologies. En utilisant le tableau proposé par É. Bérard, nous avons observé les types de tâches qui apparaissent dans les quatre premiers dossiers de la méthode du français langue étrangère Alter Ego 2 (niveau A2). Nous avons donné des exemples des types de tâches qui sont les plus fréquentes dans notre méthode. En supposant que chaque type de tâche soit également présenté dans un manuel du FLE, nous avons énuméré tous les types de tâches et nous avons écrit les résultats dans le tableau choisi. Grâce aux résultats obtenus et en utilisant une analyse qualitative, nous pouvions voir quels types de tâches sont les plus fréquents
Epidemiology, Practice of Ventilation and Outcome for Patients at Increased risk of Postoperative Pulmonary Complications: Las Vegas - an Observational Study in 29 Countries
BACKGROUND Limited information exists about the epidemiology and outcome of surgical patients at increased risk of postoperative pulmonary complications (PPCs), and how intraoperative ventilation was managed in these patients.
OBJECTIVES To determine the incidence of surgical patients at increased risk of PPCs, and to compare the intraoperative ventilation management and postoperative outcomes with patients at low risk of PPCs.
DESIGN This was a prospective international 1-week observational study using the ‘Assess Respiratory Risk in Surgical Patients in Catalonia risk score’ (ARISCAT score) for PPC for risk stratification.
PATIENTS AND SETTING Adult patients requiring intraoperative ventilation during general anaesthesia for surgery in 146 hospitals across 29 countries.
MAIN OUTCOME MEASURES The primary outcome was the incidence of patients at increased risk of PPCs based on the ARISCAT score. Secondary outcomes included intraoperative ventilatory management and clinical outcomes.
RESULTS A total of 9864 patients fulfilled the inclusion criteria. The incidence of patients at increased risk was 28.4%. The most frequently chosen tidal volume (VT) size was 500 ml, or 7 to 9 ml kg1 predicted body weight, slightly lower in patients at increased risk of PPCs. Levels of positive end-expiratory pressure (PEEP) were slightly higher in patients at increased risk of PPCs, with 14.3% receiving more than 5 cmH2O PEEP compared with 7.6% in patients at low risk of PPCs (P < 0.001). Patients with a predicted preoperative increased risk of PPCs developed PPCs more frequently: 19 versus 7%, relative risk (RR) 3.16 (95% confidence interval 2.76 to 3.61), P < 0.001) and had longer hospital stays. The only ventilatory factor associated with the occurrence of PPCs was the peak pressure.
CONCLUSION The incidence of patients with a predicted increased risk of PPCs is high. A large proportion of patients receive high VT and low PEEP levels. PPCs occur frequently in patients at increased risk, with worse clinical outcome
Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study
Background: Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings of patients undergoing neurosurgical procedures, and to explore the association between perioperative variables and the development of PPCs in neurosurgical patients.
Methods: Post-hoc analysis of LAS VEGAS study, restricted to patients undergoing neurosurgery. Patients were stratified into groups based on the type of surgery (brain and spine), the occurrence of PPCs and the assess respiratory risk in surgical patients in Catalonia (ARISCAT) score risk for PPCs.
Results: Seven hundred eighty-four patients were included in the analysis; 408 patients (52%) underwent spine surgery and 376 patients (48%) brain surgery. Median tidal volume (VT) was 8 ml [Interquartile Range, IQR = 7.3-9] per predicted body weight; median positive end-expiratory pressure (PEEP) was 5 [3 to 5] cmH20. Planned recruitment manoeuvres were used in the 6.9% of patients. No differences in ventilator settings were found among the sub-groups. PPCs occurred in 81 patients (10.3%). Duration of anaesthesia (odds ratio, 1.295 [95% confidence interval 1.067 to 1.572]; p = 0.009) and higher age for the brain group (odds ratio, 0.000 [0.000 to 0.189]; p = 0.031), but not intraoperative ventilator settings were independently associated with development of PPCs.
Conclusions: Neurosurgical patients are ventilated with low VT and low PEEP, while recruitment manoeuvres are seldom applied. Intraoperative ventilator settings are not associated with PPCs
Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: Post-hoc analysis of LAS VEGAS study
Background: Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings of patients undergoing neurosurgical procedures, and to explore the association between perioperative variables and the development of PPCs in neurosurgical patients. Methods: Post-hoc analysis of LAS VEGAS study, restricted to patients undergoing neurosurgery. Patients were stratified into groups based on the type of surgery (brain and spine), the occurrence of PPCs and the assess respiratory risk in surgical patients in Catalonia (ARISCAT) score risk for PPCs. Results: Seven hundred eighty-four patients were included in the analysis; 408 patients (52%) underwent spine surgery and 376 patients (48%) brain surgery. Median tidal volume (VT) was 8 ml [Interquartile Range, IQR = 7.3-9] per predicted body weight; median positive end-expiratory pressure (PEEP) was 5 [3 to 5] cmH20. Planned recruitment manoeuvres were used in the 6.9% of patients. No differences in ventilator settings were found among the sub-groups. PPCs occurred in 81 patients (10.3%). Duration of anaesthesia (odds ratio, 1.295 [95% confidence interval 1.067 to 1.572]; p = 0.009) and higher age for the brain group (odds ratio, 0.000 [0.000 to 0.189]; p = 0.031), but not intraoperative ventilator settings were independently associated with development of PPCs. Conclusions: Neurosurgical patients are ventilated with low VT and low PEEP, while recruitment manoeuvres are seldom applied. Intraoperative ventilator settings are not associated with PPCs
Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study
Background: Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings of patients undergoing neurosurgical procedures, and to explore the association between perioperative variables and the development of PPCs in neurosurgical patients.
Methods: Post-hoc analysis of LAS VEGAS study, restricted to patients undergoing neurosurgery. Patients were stratified into groups based on the type of surgery (brain and spine), the occurrence of PPCs and the assess respiratory risk in surgical patients in Catalonia (ARISCAT) score risk for PPCs.
Results: Seven hundred eighty-four patients were included in the analysis; 408 patients (52%) underwent spine surgery and 376 patients (48%) brain surgery. Median tidal volume (VT) was 8 ml [Interquartile Range, IQR = 7.3-9] per predicted body weight; median positive end-expiratory pressure (PEEP) was 5 [3 to 5] cmH20. Planned recruitment manoeuvres were used in the 6.9% of patients. No differences in ventilator settings were found among the sub-groups. PPCs occurred in 81 patients (10.3%). Duration of anaesthesia (odds ratio, 1.295 [95% confidence interval 1.067 to 1.572]; p = 0.009) and higher age for the brain group (odds ratio, 0.000 [0.000 to 0.189]; p = 0.031), but not intraoperative ventilator settings were independently associated with development of PPCs.
Conclusions: Neurosurgical patients are ventilated with low VT and low PEEP, while recruitment manoeuvres are seldom applied. Intraoperative ventilator settings are not associated with PPCs