Cosmological Models with Variable Gravitational and Cosmological constants in R2R^{2} Gravity

We consider the evolution of a flat Friedmann-Roberstson-Walker Universe in a higher derivative theories, including $\alpha R^{2}$ terms to the Einstein-Hilbert action in the presence of a variable gravitational and cosmological constants. We study here the evolution of the gravitational and cosmological constants in the presence of radiation and matter domination era of the universe. We present here new cosmological solutions which are physically interesting for model building.Comment: 14 pages, no figure. to be published in Int. J. Mod. Phys.

Spherically symmetric vacuum solutions of modified gravity theory in higher dimensions

In this paper we investigate spherically symmetric vacuum solutions of $f(R)$ gravity in a higher dimensional spacetime. With this objective we construct a system of non-linear differential equations, whose solutions depend on the explicit form assumed for the function $F(R)=\frac{df(R)}{dR}$. We explicit show that for specific classes of this function exact solutions from the field equations are obtained; also we find approximated results for the metric tensor for more general cases admitting $F(R)$ close to the unity.Comment: 14 pages, no figure. New version accepted for publication in EPJ

Density perturbations in an Universe dominated by the Chaplygin gas

We study the fate of density perturbations in an Universe dominate by the Chaplygin gas, which exhibit negative pressure. We show that it is possible to obtain the value for the density contrast observed in large scale structure of the Universe by fixing a free parameter in the equation of state of this gas. The negative character of pressure must be significant only very recently.Comment: Latex file, 5 page

Graviton mass and total relative density of mass Omega_tot in Universe

It is noticed that the total relative density of mass in the Universe Omega_tot should exceed 1, i.e. Omega_tot=1+f^2/6 according to the field relativistic theory of gravity (RTG), which is free of the cosmological singularity and which provides the Euclidean character for the 3-dimensional space. Here f is the ratio of the graviton mass m_g to the contemporary value of the ``Hubble mass'' m^0_H=\hbar H_0/c^2\simeq 3,8\cdot 10^{-66}h(g) (h=0,71\pm0,07). Applying results of the experimental data processing presented in [1] an upper limit for the graviton mass is established as m_g\leq 3,2\cdot 10^{-66}g at the 95% confidence level.Comment: 8 pages, latex fil

Scalar fields in an anisotropic closed universe

We study in this article a class of homogeneous, but anisotropic cosmological models in which shear viscosity is included. Within the matter content we consider a component (the quintessence component) determined by the barotropic equations of state, $p=\alpha \rho$, with $\alpha < 0$. We establish conditions under which a closed axisymmetrical cosmological model may look flat al low redshift.Comment: 6 pages, Latex, 2 figures, accepted in Phys. Rev.

An asymmetric explosion as the origin of spectral evolution diversity in type Ia supernovae

Type Ia Supernovae (SNe Ia) form an observationally uniform class of stellar explosions, in that more luminous objects have smaller decline-rates. This one-parameter behavior allows SNe Ia to be calibrated as cosmological `standard candles', and led to the discovery of an accelerating Universe. Recent investigations, however, have revealed that the true nature of SNe Ia is more complicated. Theoretically, it has been suggested that the initial thermonuclear sparks are ignited at an offset from the centre of the white-dwarf (WD) progenitor, possibly as a result of convection before the explosion. Observationally, the diversity seen in the spectral evolution of SNe Ia beyond the luminosity decline-rate relation is an unresolved issue. Here we report that the spectral diversity is a consequence of random directions from which an asymmetric explosion is viewed. Our findings suggest that the spectral evolution diversity is no longer a concern in using SNe Ia as cosmological standard candles. Furthermore, this indicates that ignition at an offset from the centre of is a generic feature of SNe Ia.Comment: To appear in Nature, 1st July 2010 issue. 36 pages including supplementary materials. 4 figures, 3 supplementary figures, 1 supplementary tabl

Realistic Equations of State for the Primeval Universe

Early universe equations of state including realistic interactions between constituents are built up. Under certain reasonable assumptions, these equations are able to generate an inflationary regime prior to the nucleosynthesis period. The resulting accelerated expansion is intense enough to solve the flatness and horizon problems. In the cases of curvature parameter \kappa equal to 0 or +1, the model is able to avoid the initial singularity and offers a natural explanation for why the universe is in expansion.Comment: 32 pages, 5 figures. Citations added in this version. Accepted EPJ

American Society of Clinical Oncology/College ofAmerican Pathologists guideline recommendations forimmunohistochemical testing of estrogen andprogesterone receptors in breast cancer

Purpose: To develop a guideline to improve theaccuracy of immunohistochemical (IHC) estrogen receptor(ER) and progesterone receptor (PgR) testing in breastcancer and the utility of these receptors as predictivemarkers.Methods: The American Society of Clinical Oncologyand the College of American Pathologists convened aninternational Expert Panel that conducted a systematicreview and evaluation of the literature in partnership withCancer Care Ontario and developed recommendations foroptimal IHC ER/PgR testing performance.Results: Up to 20% of current IHC determinations ofER and PgR testing worldwide may be inaccurate (falsenegative or false positive). Most of the issues with testinghave occurred because of variation in preanalyticvariables, thresholds for positivity, and interpretationcriteria.Recommendations: The Panel recommends that ER andPgR status be determined on all invasive breast cancers andbreast cancer recurrences. A testing algorithm that relieson accurate, reproducible assay performance is proposed.Elements to reliably reduce assay variation are specified. It is recommended that ER and PgR assays be consideredpositive if there are at least 1% positive tumor nuclei in the sample on testing in the presence of expected reactivity of internal (normal epithelial elements) and external controls. The absence of benefit from endocrine therapy for women with ER-negative invasive breast cancers has been confirmed in large overviews of randomized clinical trials.(Arch Pathol Lab Med. 2010;134:907–922