Constraining the Dark Universe

We combine complementary datasets to constrain dark energy. Using standard Big Bang Nucleosynthesis and the observed abundances of primordial nuclides to put constraints on $\Omega_Q$ at temperatures near $T \sim 1MeV$, we find the strong constraint $\Omega_Q({MeV}) < 0.045$ at $2\sigma$ c.l.. Under the assumption of flatness, using results from Cosmic Microwave Background (CMB) anisotropy measurements, high redshift supernovae (SN-Ia) observations and data from local cluster abundances we put a new constraint on the equation of state parameter $w_Q < -0.85$ at 68% c.l..Comment: 5 pages, 3 figures, new reference added. To appear in the proceedings of TAUP 2001 (7th international workshop on Topics in Astroparticle and Underground Physics), Sep 2001, Laboratori Nazionali del Gran Sasso, Assergi, Ital

Darboux class of cosmological fluids with time-dependent adiabatic indices

A one-parameter family of time dependent adiabatic indices is introduced for any given type of cosmological fluid of constant adiabatic index by a mathematical method belonging to the class of Darboux transformations. The procedure works for zero cosmological constant at the price of introducing a new constant parameter related to the time dependence of the adiabatic index. These fluids can be the real cosmological fluids that are encountered at cosmological scales and they could be used as a simple and efficient explanation for the recent experimental findings regarding the present day accelerating universe. In addition, new types of cosmological scale factors, corresponding to these fluids, are presentedComment: document with the following three latex files: 1) quhm.tex: 17 pages, 10 figs, 16 numbered refs, Honorable Mention GRF 2000, 2) errad.tex: Errata and Addenda (EaA) of 5 pages with 2 figs enclosed, 3) analogy.tex: Negative friction of Darboux cosmological fluids of 4 page

Phantom Energy Accretion by Stringy Charged Black Hole

We investigate the dynamical behavior of phantom energy near stringy magnetically charged black hole. For this purpose, we derive equations of motion for steady-state spherically symmetric flow of phantom energy onto the stringy magnetically charged black hole. It is found that phantom energy accreting onto black hole decreases its mass. Further, the location of critical points of accretion is explored, which yields mass to charge ratio. This ratio implies that accretion process cannot transform a black hole into an extremal black hole or a naked singularity, hence cosmic censorship hypothesis remains valid here.Comment: 7 pages, no figur

Cosmological constant influence on cosmic string spacetime

We investigate the line element of spacetime around a linear cosmic string in the presence of a cosmological constant. We obtain the metric and argue that it should be discarded because of asymptotic considerations. Then a time dependent and consistent form of the metric is obtained and its properties are discussed.Comment: 3 page

Phantom Accretion onto the Schwarzschild de-Sitter Black Hole

We deal with phantom energy accretion onto the Schwarzschild de-Sitter black hole. The energy flux conservation, relativistic Bernoulli equation and mass flux conservation equation are formulated to discuss the phantom accretion. We discuss the conditions for critical accretion. It is found that mass of the black hole decreases due to phantom accretion. There exist two critical points which lie in the exterior of horizons (black hole and cosmological horizons). The results for the phantom energy accretion onto the Schwarzschild black hole can be recovered by taking $\Lambda\rightarrow0$.Comment: 9 pages, no figur

Stochastic simulation of vertically nonhomogeneous gusts

The small-scale horizontal gust structure of detailed wind profiles along the vertical in the first 20 km of the atmosphere is a vertically nonhomogeneous process. A linear stochastic model was developed based on the process covariance function. This model was formulated through the use of a scaling hypothesis which transforms the nonhomogeneous gust process into a nondimensional gust process which is homogeneous in a nondimensional gust height coordinate. The velocity scaling parameter for the gust process is the gust standard deviation, and the length scale used to nondimensionalize the altitude is the vertical space lag associated with the first zero of the gust covariance function. State space theory was used to derive a digital filter from the model, which can be readily used to simulate gusts for space vehicle design applications

Natural extension of the Generalised Uncertainty Principle

We discuss a gedanken experiment for the simultaneous measurement of the position and momentum of a particle in de Sitter spacetime. We propose an extension of the so-called generalized uncertainty principle (GUP) which implies the existence of a minimum observable momentum. The new GUP is directly connected to the nonzero cosmological constant, which becomes a necessary ingredient for a more complete picture of the quantum spacetime.Comment: 4 pages, 1 figure, v2 with added references, revised and extended as published in CQ

Quantitative assessment of cell fate decision between autophagy and apoptosis

Abstract Autophagy and apoptosis are cellular processes that regulate cell survival and death, the former by eliminating dysfunctional components in the cell, the latter by programmed cell death. Stress signals can induce either process, and it is unclear how cells ‘assess’ cellular damage and make a ‘life’ or ‘death’ decision upon activating autophagy or apoptosis. A computational model of coupled apoptosis and autophagy is built here to analyze the underlying signaling and regulatory network dynamics. The model explains the experimentally observed differential deployment of autophagy and apoptosis in response to various stress signals. Autophagic response dominates at low-to-moderate stress; whereas the response shifts from autophagy (graded activation) to apoptosis (switch-like activation) with increasing stress intensity. The model reveals that cytoplasmic Ca2+ acts as a rheostat that fine-tunes autophagic and apoptotic responses. A G-protein signaling-mediated feedback loop maintains cytoplasmic Ca2+ level, which in turn governs autophagic response through an AMP-activated protein kinase (AMPK)-mediated feedforward loop. Ca2+/calmodulin-dependent kinase kinase β (CaMKKβ) emerges as a determinant of the competing roles of cytoplasmic Ca2+ in autophagy regulation. The study demonstrates that the proposed model can be advantageously used for interrogating cell regulation events and developing pharmacological strategies for modulating cell decisions

Is the Pre-WMAP CMB Data Self-consistent?

Although individual observational groups vigorously test their data sets for systematic errors, the pre-WMAP CMB observational data set has not yet been collectively tested. Under the assumption that the concordance model is the correct model, we have explored residuals of the observational data with respect to this model to see if any patterns emerge that can be identified with systematic errors. We found no significant trends associated with frequency, frequency channels, calibration source, pointing uncertainty, instrument type, platform and altitude. We did find some evidence at the ~ 1 to ~ 2 sigma level for trends associated with angular scale (l range) and absolute galactic latitude. The slope of the trend in galactic latitude is consistent with low level galactic contamination. The residuals with respect to l may indicate that the concordance model used here needs slight modification. See Griffiths & Lineweaver (2003) for more detail.Comment: 8 pages, 4 figures, to be published in the proceedings of "The Cosmic Microwave Background and its Polarization", New Astronomy Reviews, (eds. S. Hanany and K.A. Olive

Is the Lambda CDM Model Consistent with Observations of Large-Scale Structure?

The claim that large-scale structure data independently prefers the Lambda Cold Dark Matter model is a myth. However, an updated compilation of large-scale structure observations cannot rule out Lambda CDM at 95% confidence. We explore the possibility of improving the model by adding Hot Dark Matter but the fit becomes worse; this allows us to set limits on the neutrino mass.Comment: To appear in Proceedings of "Sources and Detection of Dark Matter/Energy in the Universe", ed. D. B. Cline. 6 pages, including 2 color figure