Protein imprinting by means of alginate-based polymers

Methods of preparing molecularly imprinted polymers are provided. In one embodiment, a method comprises providing a solution comprising a template molecule; and forming a product comprising calcium alginate in the presence of the template molecule so that the template molecule is imprinted in the product.Board of Regents, University of Texas Syste

Preschool Metacognitive Skill Assessment in Order to Promote Educational Sensitive Response From Mixed-Methods Approach: Complementarity of Data Analysis

A child''s metacognitive skills contribute significantly to their learning and success. However, very few studies are focused on these skills at early education andmost of them are carried out from inappropriate methodological perspectives for the characteristics of the youngest students. To overcome such limitations, it is essential to carry out observational studies that analyze children''s metacognitive behaviors in the natural and habitual context of children''s learning, as well as appropriate tasks for their level of development. The aim of this study was to analyze the sequential and associative structure of the metacognitive skills used by 5-year-old children throughout the resolution of a playful task (a puzzle). It was interesting to know if there were different hidden structures in the use of metacognitive skills in the children who solved the puzzle and those who did not. From the methodological approach, this work was located in the perspective of mixed methods which is characterized by the integration of qualitative and quantitative elements. This integration was carried out from the "connect" option. The integration involved developing quantitizing, as one of its possibilities. Recent scientific literature has considered systematic observation, in which the QUAL-QUAN-QUAL macro stages take place, as a mixed method itself. Consequently, systematic observation was applied, because it was suitable for our aim. A Nomothetic/Punctual/Multidimensional observational design was used. The playful activity of 44 preschool children solving the puzzle individually was coded. It allowed us to obtain data matrices that respond to the QUAL stage. Regarding the QUAN stage, once the quality of data was controlled, the records were further analyzed by differentiating two groups of participants (those who had solved the puzzle and those who did not) using three quantitative techniques of observational analysis (T-pattern detection, lag sequential analysis, polar coordinate analysis). Finally data was returned to a QUAL stage to interpret the results. The use of these three techniques allowed a detailed and in-depth analysis of the children''s activity. Results reveal differences in the metacognitive abilities of the children that solved and didn''t solve the puzzle. These results have important implications for educational practice

Kinetics of formic acid dehydration on Pt electrodes by time-resolved ATR-SEIRAS

ACKNOWLEDGMENT L.P.-M. acknowledges a doctoral scholarship within the Leverhulme Centre for Doctoral Training in Sustainable Production of Chemicals and Materials (Grant DS-2017-073).Peer reviewedPublisher PD

The Importance of the Assembly in Thermoelectric Generators

Generally, in the optimization of thermoelectric generators, only the heat exchangers or the thermoelectric modules themselves are taken into account. However, the assembly of the generator as a whole is of vital importance since a bad contact or a thermal bridge can waste the performance of an optimal generator. In this sense, the present chapter analyzes experimentally the use of different interface materials to reduce the thermal contact resistance between the modules and the heat exchangers, the influence of the pressure distribution in the assembly as well as the effect of different insulating materials in order to reduce the thermal bridge between the exchangers. Thus, it has been demonstrated that a good assembly requires the implementation of thermal interface materials to ensure the microscopic contact between the heat exchangers and the modules, besides a uniform clamping pressure. Nevertheless, since this is normally achieved with screws, they represent a source of thermal bridges in conjunction with the small distance between the exchangers. In order to reduce heat losses due to thermal bridges, which can represent up to one-third of the incoming heat, an increment of the distance between the exchangers and the use of an insulator is recommended

Evidencia en fluidoterapia perioperatoria. Un tema aún pendiente.

Intravenous fluid therapy is a key component in the protocols and clinical pathways in enhanced recovery after surgery protocols. This article reviews the new recommendations based on current evidence: from the limitation of preoperative fasting and hemodynamic monitoring of the systolic volume, to a restrictive but permissive balance in the intraoperative and rapid recovery of the oral route in the first hours of surgery. Perioperative patients with hypotension or evidence of inadequate tissue perfusion should first be fluid-optimized before implementation of vasopressor therapy.La fluidoterapia intravenosa constituye uno de los pilares fundamentales en los protocolos y vías clínicas de optimización de recuperación postquirúrgica. En este artículo se revisan las nuevas recomendaciones en base a la evidencia actual: desde la limitación del ayuno preoperatorio y la monitorización hemodinámica del volumen sistólico, pasando por un balance hídrico restrictivo y permisivo en el intraoperatorio y la recuperación rápida de la vía oral en las primeras horas de la intervención. En caso de hipotensión o registro de perfusión tisular deficiente, se debe optimizar la volemia antes de iniciar tratamientos inotrópicos o vasopresores.