Relation between organizational commitment and professional commitment: an exploratory study conducted with teachers

The existence of several kinds of commitments in the workplace is well known. However, there are few studies that relate these different commitments or those established by deterministic models. This study explored the relationship between organizational and professional commitment in public higher education professors according to the multidimensional perspective of Meyer and Allen (1991), based on a convenience sample of 219 teachers. The proposed models were estimated through structural equation modeling methodology. Model 1 specified a relationship of direct influence of Professional Commitment on Organizational Commitment and Model 2 established the opposite relationship of direct influence of organizational commitment on professional commitment. Both models presented a good fit to the data without statistically significant differences between them. Nevertheless, the explanatory power of Model 1 was superior to Model 2, due to the fact that it includes a larger number of determinant relationships that are statistically significant. Theoretical and practical implications were discussed and new directions for future research were identified.info:eu-repo/semantics/publishedVersio

Motor dysfunctions and neuropathology in mouse models of spinocerebellar ataxia type 2: A comprehensive review

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant ataxia caused by an expansion of CAG repeats in the exon 1 of the gene ATXN2, conferring a gain of toxic function that triggers the appearance of the disease phenotype. SCA2 is characterized by several symptoms including progressive gait ataxia and dysarthria, slow saccadic eye movements, sleep disturbances, cognitive impairments, and psychological dysfunctions such as insomnia and depression, among others. The available treatments rely on palliative care, which mitigate some of the major symptoms but ultimately fail to block the disease progression. This persistent lack of effective therapies led to the development of several models in yeast, C. elegans, D. melanogaster, and mice to serve as platforms for testing new therapeutic strategies and to accelerate the research on the complex disease mechanisms. In this work, we review 4 transgenic and 1 knock-in mouse that exhibit a SCA2-related phenotype and discuss their usefulness in addressing different scientific problems. The knock-in mice are extremely faithful to the human disease, with late onset of symptoms and physiological levels of mutant ataxin-2, while the other transgenic possess robust and well-characterized motor impairments and neuropathological features. Furthermore, a new BAC model of SCA2 shows promise to study the recently explored role of non-coding RNAs as a major pathogenic mechanism in this devastating disorder. Focusing on specific aspects of the behavior and neuropathology, as well as technical aspects, we provide a highly practical description and comparison of all the models with the purpose of creating a useful resource for SCA2 researchers worldwide

Motor Competence, Weight and Bullying

The purpose of this study was to compare the prevalence of motor competence among children and adolescents from two metropolitan cities, one in Portugal and one in Brazil, and analyzed the association between motor competence and weight status and bullying roles. A Cross-sectional and cross-cultural study was applied. The sample comprised 785 children and adolescents aged 7-14. Motor competence was assessed using The Körperkoordinationtest Für Kinder (KTK) test, while participation in bullying was assessed using a sociometric test and the students’ Body Mass Index (BMI), which was calculated from height and weight and reported as kg/m2. Portuguese students had a higher prevalence of impairment/disturbance in motor coordination. Also, obese students and bullying victims had higher odds of having a motor competence below normal values in both countries. These findings provide evidence of a link between motor competence and sex and weight status of schoolchildren and suggest that motor competence is associated with bullying roles.Este trabalho foi financiado por Fundos Nacionais através da FCT – Fundação para a Ciência e a Tecnologia no âmbito dos projetos do CIEC (Centro de Investigação em Estudos da Criança da Universidade do Minho) com as referências UIDB/00317/2020 e UIDP/00317/2020.Coordenadoria de Aperfeiçoamento de Pessoal de Nivel Superior – CAPES [grant numbers 0815 / 14-4; 1663167].PROGRAMA UNIEDU PÓS-GRADUAÇÃO - UNIED

What We Know About the Genetic Determinants of Human Homosexuality? A Short Review Communication

“Homosexualism”, “sexual orientation disorder”, “egodistonic homosexuality”, “unspecified sexual disorder”, “sexual maturity disorder” and “sexual relationship disorder”. Since 1948, these have been, throughout the history of the Diagnostic and Statistical Manual of Mental Disorders (DCM) and the International Statistical Classification of Diseases and Related Health Problems (ICD), the terms used by the scientific community to categorize the homoaffective spectrum until in 2017, in the face of strong social and academic demand, their complete disengagement from any terminology that categorizes them as physical and/or mental illness. On the other hand, some areas of science have contributed substantially to a better understanding of this subject, such as genetics and epigenetics. Today, although the scientific community still offers some points of resistance, especially in more conservative countries, it is a consensus that since the implementation of the genome project there has been a considerable methodological expansion that has opened new possibilities of studies that have allowed this advance

Fatigue design in reinforced concrete bridges according to Brazilian code

There has been an increase in the flow of freight vehicles commuting on Brazilian highways. Then, special attention to the structural performance of bridges regarding the fatigue in beams is needed. Brazil has neither normative metrology to study real data flow of vehicles, nor specific fatigue load train models and coefficients to the analysis and design of road bridges. The same load train that is used for general dimensioning, TB 450, is used for the fatigue verification. Hence, this work aims to verify if the current TB 450 is representative of the freight heavy vehicles with 2 to 9 axles concerning the effects of fatigue in the longitudinal reinforcement of beams of theoretical reinforced concrete bridges with two, three, and five beams. This verification is performed analyzing the stress variations found in the longitudinal reinforcement of vehicles with 2 to 9 axles and the TB 450. Based on the results, the longitudinal steel reinforcement was more susceptible to fatigue\u27s effects. Freight vehicles with 5, 6, 8 and 9 axles presented the most significant stress, therefore, they tend to cause more deleterious effects. Hence, the adoption of a Brazilian normative fatigue specific load train and coefficients is necessary to analyze pre-existing road bridges and design new ones most accurately

Uma possibilidade de reconstrução do laço social entre professores, alunos e comunidade

This article comes from an activity proposed for teachers from the public network, in a pedagogical training course, where individual narratives were produced about the challenges for a better learning of students. With these narratives, we seek to find a common characteristic capable of promoting a reflective dialogue. We adopted the technique of discursive textual analysis giving rise to three categories: Motivation, Digital Technology and Meaningful Learning. We identified in teachers a certain sense of isolation, caused by the lack of interest of students and the community in school activities. We conclude by pointing to the relevance of thought and hermeneutic exercise as an ethical dialogue in the reconstruction of the social bond between teachers, students and the community.Este artículo proviene de una actividad propuesta para maestros de escuelas públicas, en un curso de capacitación pedagógica, donde se produjeron narrativas individuales sobre los desafíos para un mejor aprendizaje de los estudiantes. Con estas narrativas buscamos encontrar una característica común capaz de promover un diálogo reflexivo. Adoptamos la técnica de análisis textual discursivo que da lugar a tres categorías: motivación, tecnología digital y aprendizaje significativo. Identificamos en los maestros un cierto sentimiento de aislamiento, causado por la falta de interés de los estudiantes y la comunidad en las actividades escolares. Concluimos señalando la relevancia del pensamiento hermenéutico y el ejercicio como diálogo ético en la reconstrucción del vínculo social entre docentes, estudiantes y la comunidad.O presente artigo é oriundo de uma atividade proposta para professores da rede pública, em um curso de formação pedagógica, onde foram produzidas narrativas individuais sobre os desafios para uma melhor aprendizagem dos alunos. De posse dessas narrativas buscamos encontrar uma característica comum capaz de promover um diálogo reflexivo. Adotamos a técnica de análise textual discursiva dando origem a três categorias: Motivação, Tecnologia digital e Aprendizagem Significativa. Identificamos nos professores um certo sentimento de isolamento, causado pela falta de interesse dos alunos e da comunidade nas atividades escolares. Concluímos apontando para relevância do pensamento e do exercício hermenêutico enquanto diálogo ético na reconstrução do laço social entre professores, alunos e comunidade

Estudo comparativo de duas diferentes modalidades de analgesia controlada pelo paciente após cirurgia cardíaca

INTRODUCTION: Acute and severe pain is frequent in patients who undergo cardiothoracic surgery. Patient controlled analgesia (PCA) can be used to manage postoperative pain. OBJECTIVE: To compare analgesia of morphine PCA alone (without continous infusion) with morphine PCA plus a continuous infusion on postoperative period after cardiac surgery and to evaluate pain scores, morphine consumption, number of demand, patient satisfaction and side effects. METHODS: Randomized trial was conducted to assess patients who underwent cardiac surgery receiving either morphine PCA alone or morphine PCA plus continous infusion. In the post operative period, PCA was started at extubation in both regiments according to randomization. Pain intensity, morphine consumption, number of demand, satisfaction and side effects were assessed at zero, six, twelve, eighteen, twenty four and thirty hours after patients' extubation. RESULTS: The study enrolled 100 patients. 50 patients received morphine PCA alone, (Group A) and 50 patients received morphine PCA plus a background infusion, (Group B). Group B patients had less demand, consumed more morphine and were more satisfied regarding analgesia. No statistical differences were shown between groups related to pain intensity, and side effects. CONCLUSIONS: Pain control was effective and similar in both groups. Morphine PCA alone seems to be better for postoperative pain manage in cardiac surgery, due to its less morphine expense with the same effectiveness.INTRODUÇÃO: A dor aguda e intensa faz parte do cotidiano dos pacientes que realizam cirurgia cardíaca, e para o controle da dor, pode-se dispor da analgesia controlada pelo paciente (PCA -Patient controlled analgesia). OBJETIVO: Comparar a analgesia utilizando PCA sem infusão contínua com PCA mais infusão contínua de morfina no pós-operatório de cirurgia cardíaca e avaliar a intensidade dolorosa, consumo analgésico, número de solicitações analgésicas, satisfação e efeitos colaterais. MÉTODOS: Ensaio clínico randomizado em que foram estudados pacientes submetidos a cirurgias cardíacas, que utilizaram PCA com e sem infusão intravenosa de morfina. No pós-operatório, ao se extubar os pacientes, foi instalada PCA nas duas modalidades, conforme o sorteio. Intensidade dolorosa, consumo analgésico, número de solicitações analgésicas, satisfação e efeitos colaterais foram avaliados no momento da extubação e nas 6, 12, 18, 24 e 30 horas seguintes. RESULTADOS: Foram avaliados 100 pacientes, sendo 50 no grupo (A) que recebeu PCA sem infusão contínua de morfina, e 50 no grupo (B) que utilizou PCA com infusão contínua de morfina. Pacientes do grupo (B) consumiram mais morfina, solicitaram menos vezes, e ficaram mais satisfeitos com a analgesia. Não se observaram diferenças significantes entre os grupos quanto à intensidade da dor e aos efeitos colaterais. CONCLUSÕES: O controle da dor foi eficiente e similar em ambos os grupos estudados. A mesma eficácia de analgesia e o menor consumo de morfina sugerem que PCA sem infusão contínua de morfina seja a melhor opção no controle da dor no pós-operatório de cirurgia cardíaca.Clinics HospitalFederal University of São PauloHeart InstituteHeart Institute Heart Surgical Diseases GroupUNIFESPSciEL

Graves disease and IgA deficiency as manifestations of 22q11.2 deletion syndrome:

A síndrome de deleção 22q11.2 (SD22q11.2) está associada à alta variabilidade fenotípica, abrangendo o espectro velocardiofacial/síndrome de DiGeorge. Manifestações autoimunes, endocrinológicas e de imunodeficiência vêm sendo relatadas associadas à síndrome. O objetivo deste estudo foi relatar um caso de SD22q11.2 associado à deficiência de IgA e à doença de Graves e rever a literatura visando verificar a frequência dessas alterações na SD22q11.2. Os distúrbios autoimunes, cada vez mais relacionadas a SD22q11.2 e novos fenótipos, vêm sendo incorporadas ao seu espectro clínico. No presente estudo, verificou-se que a doença de Graves associada à SD22q11.2 foi relatada em apenas dezesseis pacientes e quinze descritos na literatura nos últimos 13 anos. Com base na incidência e na amplitude de seu espectro de manifestações já reconhecidas, reforçaram-se os achados da literatura de que a doença de Graves deve ser incluída nas manifestações da SD22q11.2, o que nos levaria a pesquisá-la nos portadores da deleção 22q11.2.The 22q11.2 deletion syndrome (22q11.2DS) is related to a high phenotypic variability including the velocardiofacial/DiGeorge spectrum. Autoimmune, endocrine and immunodeficiency manifestations have been reportedly associated with the syndrome. The objective of this study was to report a case of 22q11.2DS associated with IgA deficiency and Graves disease and review literature in order to verify the frequency of syndrome alterations. Autoimmune disorders have been increasingly related to 22q11.2DS, and new phenotypes are being incorporated in the clinical spectrum of this syndrome. In our study we found that Graves disease in association with 22q11.2DS was reported in only sixteen patients, and fifteen cases were described in the last 13 years. Based on the incidence and on the amplitude of this recognized spectrum, we reinforce the findings of literature that Graves disease should be included on the 22q11.2DS manifestations, which would lead us to seek it with 22q11.2 deletion patients

MORPHOLOGIC AND MOLECULAR CHARACTERIZATION OF SPECIES OF Myrciaria spp

A Jabuticabeira é considerada como uma das fruteiras mais típicas do Brasil, contudo há poucos estudos desta planta na literatura e mesmo na literatura especializada, existem muitas controvérsias sobre sua classificação. Este trabalho faz comparações entre as espécies de Jabuticabeiras, usando as técnicas de marcadores morfológicos (Organografia) e moleculares (RAPD). As características morfológicas das plantas, usadas como marcadores morfológicos, foram comparadas com espécimes presentes nos herbários dos Estados de São Paulo e Minas Gerais e através da revisão de literatura especializada. As diferenças moleculares entre as espécies foi determinada através do uso de marcadores moleculares (RAPD). O experimento foi realizado nas cidades de Piracicaba, Jaboticabal e Ituverava, São Paulo, Brasil. Diferenças morfológicas e moleculares entre as plantas estudadas foram identificadas e as mesmas foram agrupadas em quatro grupos distintos, as espécies identificadas foram: Myrciaria cauliflora (Mart.) O. Berg, Myrciaria coronata Mattos, Myrciaria jaboticaba (Vell.) O. Berg., Myrciaria phytrantha (Kiaersk.) Mattos. A técnica de marcadores moleculares aliada à técnica de marcadores morfológicos (organografia), mostrou ser uma ferramenta importante na identificação de espécies de jabuticabeiras. Palavras-chave: Myrciaria, jabuticabeiras, marcadores morfológicos, marcadores moleculares (RAPD)The jabuticaba tree is considered one of the most tipical brasilian fruit tree, however, there are a little of studies of this plant in the literature and even in the specilized literature, there are controversies about its classification many. The present work makes some comparisons between jabuticaba species, using morphologic markers (organography) and molecular markers (RAPD) technique. The morphologic characteristics of the plants, used as morphologic markers, were compared with specimens present on herbaria from São Paulo and Minas Gerais states and through the revision of specialized literature. Molecular differences between the species were identified by molecular in Piracicaba, Jaboticabal and Ituverava cities, São Paulo, Brasil. Morphologic and molecular differences between the studied plants were identified and arranged in four groups, the identified species were: Myrciaria cauliflora (Mart.) O. Berg, Myrciaria coronata Mattos, Myrciaria jaboticaba (Vell.) O. Berg., Myrciaria phytrantha (Kiaersk.) Mattos. The technique of molecular markers with the technique of morphologic markers (organography) showed to be an important tool in the identification of jabuticaba tree species. Keywords: Myrciaria, biological identification, morphologic markers, molecular markers (RAPD