Analisis Peran Cuaca dan Iklim Terhadap Hasil Tangkapan Ikan Nelayan di Pesisir Utara Jawa (Pantura) di TPI (Tempat Pelelangan Ikan) Tambak Lorok Kelurahan Tanjung Mas Kecamatan Semarang Utara

Tambak Lorok area is a fishing village that has existed since 1950 and was born as a slum with a high population density. Tambak Lorok is located in the Tanjung Mas sub-district, North Semarang Sub-district, Semarang. This research was carried out with the aim of: a) knowing the amount of production of catches and types of fish in each season, b) analyzing the types of fish catches each season. The research method used in this study is the survey method which is complementary data from the village and interviewing and in-depth correspondence, with fishermen in the vicinity for samples using non-probability sampling involving purposive samples of existing businesses namely fish and fishermen traders on fish catches. and a suitable season for fishing and fishing. The results of the study (1) the production of fishermen's catches at the Tambak Lorok fish auction site that were mostly caught were petek fish (22644) tons / year and anchovy (12474) tons / year and the least number of fish per 2 year was mackerel with ( 519) ton / year (2) The number of fish caught most often is in the dry season or during the east monsoon season with the amount of 29457 tons / year while the least number of fish occurs in the rainy season or during the west monsoon season with amount of 7004 tons / year. From this analysis proves that the number of fish catches most occurs during the dry season because during the high dry season sea waves range between 0.5-1 meters, while the catch in the rainy season is slightly due to wave height ranging from 1-3 meters

Chemodectoma in a Dog

Background: The chemodectoma is a rare neoplasm that originates from chemoreceptors located mainly in the aortic body, and carotid body and sinus, and responsible for detecting variations in blood pH, oxygen pressure and carbon dioxide. Dogs of brachiocephalic breeds and aged between 7 and 15 years have greater propensity. A neoplasm involves infiltrative growth in the vessels at the heart base, which leads to Congestive Heart Failure (CHF). The definitive diagnosis is performed by histopathological and/or immunohistochemical examination. The aim was to report a case of chemiodectoma in a dog, showed the disease clinical characteristics.Case: A 13-year-old male undefined breed dog was examinated in the medical clinic of small animal of Veterinary Hospital, Federal Rural University of Pernambuco (UFRPE) with respiratory effort, hyporexia, and edema in face, cervical, ventral thorax and thoracic limbs, with thirty days evoluted. About physical examination, we observed cachexia, orthopneic position, cyanosis and edema with a positive Godet sign, as well as 8% dehydration degree. Thoracic auscultation presented mixed dyspnea and muffled heart sounds. Chest radiography detected an radiopacity increase in pulmonary section and metastatic neoplastic process associated with pleural and pericardial effusion. Fluid therapy with lactated ringer and posterior thoracentesis in the right hemithorax region was performed for greater respiratory comfort for the patient. Hematological count and biochemical profiles stated normochromic normocytic anemia, relative and absolute lymphopenia, thrombocytopenia, as well as increased alanine aminotransferase (ALT) and aspartate aminotransferase (AST). The patient died after 12 hours when was submitted to necroscopic examination and histopathological evaluation. An infiltrative tumor of cardiac base was observed invading the light of the right atrium, obstructing the venous return, as well as a large thrombus located in the left ventricle and diffuse nodules in the lungs. Hydrothorax and hydroperitoneum were observed with serous fluid, with hepatic, renal and brain congestion, and duodenum hemorrhage. Histologically, the tumor was characterized as a chemodectoma with pulmonary metastasis.Discussion: Cardiac tumors are uncommon for canine population. A study sampled 729,265 dogs with observed incidence reaching 0.19%. The most common type is hemangiosarcoma with 69%, followed by chemiodectoma and lymphoma. Authors describe predisposed brachycephalic breeds such as Boxer, Boston Terrier and French Bulldog. In our case, the patient had elongated snout and undefined breed. Deregulation of chemoreceptors, which detect changes in pH and partial oxygen and carbon dioxide pressures, can result in hyperpnea and dyspnoea. Edema represents a deficit in venous return from the cranial and cervical regions, with consequent increase in hydrostatic pressure and liquid leakage into the thoracic cavity and subcutaneous tissue, thus inferring the Caudal Vena Cava Syndrome (CVCS). Tumors from the cardiac base, integrated with the large arteries insertion and adjacent to the atria, can cause pericardial effusion observed in this case. Chemodectomas are described as essentially benign tumors with low metastatic potential. In this case, pulmonary metastasis was detected. Surgical treatment is recommended when feasible. In this case, the patient had late veterinary care, in addition to the contraindication for surgery by the lung metastasis presence

HOLOFOTES ACESOS DURANTE A PANDEMIA DA COVID-19: PARADOXOS DO PROCESSO DE TRABALHO DA ENFERMAGEM

RESUMO Objetivo: abordar de forma crítica e reflexiva os paradoxos relacionados às condições de trabalho da Enfermagem, de (des) valorização da profissão diante da pandemia da Covid-19 e da necessidade de se pensar em promoção de ambientes de trabalho saudáveis. A doença Covid-19 é uma pandemia que está influenciando os hábitos de vida e o trabalho contemporâneo. Os profissionais da Enfermagem são o maior número de trabalhadores atuantes na linha de frente no combate a essa doença. A rotina desses profissionais já era exaustiva, mas em tempos de pandemia a carga de trabalho torna-se maior e os turnos mais estressantes, devido a vários fatores como: medo de contaminação, informações deficientes, escassez de recursos humanos e materiais. Assim, torna-se urgente promover ambientes saudáveis, conforme recomenda a Organização Mundial de Saúde, visando a segurança, saúde e bem-estar dos trabalhadores. Método: estudo reflexivo realizado a partir da literatura científica e da análise crítica das autoras, abordando condições de trabalho e valorização da Enfermagem, indicando os paradoxos relacionados ao processo de trabalho. Resultados: essa reflexão abordou importantes desafios para a Enfermagem. Ao mesmo tempo em que os profissionais lutam em defesa da vida, combatendo a Covid-19 pautados em conhecimentos científicos, atitudes humanizadas e nos preceitos éticos, a profissão ainda é desvalorizada e vivencia condições de trabalho precárias. Conclusão: a expectativa é de os holofotes permanecerem acesos para a Enfermagem, mesmo após a pandemia, "iluminando" melhores condições de trabalho e reconhecimento profissional, além de ambientes laborais saudáveis com medidas concretas para o presente e o futuro

Isolation and Characterization of Plant Growth-Promotion Diazotrophic Endophytic Bacteria Associated to Sugarcane (Saccharum officinarum L.) Grown in Paraíba, Brazil

Sugarcane is an important Brazilian commodity, being usually cultivated in soils with low natural fertility. This study aimed to isolate diazotrophic endophytes from sugarcane tissues and evaluate the morphological and physiological characteristics of their colonies as well as their plant growth-promoting (PGP) traits in select diazotrophic endophytic bacteria. Fifty-six bacterial isolates were identified in the sugarcane tissues, and these isolates presented distinct morphological and physiological traits. A total of thirty-five bacterial isolates were biochemically evaluated. Overall, Bacillus was the dominant genus. Isolates of Methylobacterium spp. and Brevibacillus agri were present only in leaves, while Herbaspirillum seropedicae occurred only in stems. Except to IPA-CF45A, all isolates were nitrogenase positive. All endophytes exhibit production of indol 3-acetic acid. Over 50% of endophytes solubilize phosphate, release N-acyl homoserine lactones, and present the activity of 1-aminocyclopropane-1-carboxylic acid deaminase, catalase, lipase and protease. The network analysis showed that isolates belonged to Burkholderia, Herbaspirillum, and Methylobacterium interact with Bacillus. Bacterial endophytes exhibited distinct morphological, physiological, and PGP traits that are useful for sustainable agriculture, highlighting the isolates IPA-CC33, IPA-CF65, IPA-CC9 and IPA-CF27. Further studies on the effects of these diazotrophic endophytes and their potential for providing microbial inoculants for improving sugarcane fields will provide valuable information to maintain the sustainability and environment quality.National Council for Scientific and Technological Development 426655/2018-

A temática ambiental e a sustentabilidade nos cursos de graduação da UNIVALI: caminhos para a ambientalização curricular na universidade

Este artigo apresenta os resultados de projetos de iniciação científica dos Programas do Artigo da Lei 170, ProBIC e PIBIC vinculados a um estudo de pesquisadores do Programa de Pós-Graduação em Educação da Univali que teve por finalidade investigar o processo de ambientalização curricular nos Cursos de Graduação da Univali. Teve como objetivos elaborar um diagnóstico dos documentos curriculares dos cursos de graduação da Univali, identificar ações e projetos relativos à questão da sustentabilidade e responsabilidade socioambiental, sugerir subsídios à proposta de política institucional de ambientalização e estratégias para o Programa “Univali Sustentável”. Os sujeitos da pesquisa foram 38 professores e 10 coordenadores (as) de 12 cursos de Graduação da Univali. A abordagem metodológica caracterizou-se pelo enfoque quanti-qualitativo e o uso de técnicas de análise documental e de Análise de Conteúdo (BARDIN, 2008), com aplicação de questionário utilizando um formulário eletrônico. Como indicadores para análise a pesquisa utilizou como base as 10 características de um curso ambientalizado da Rede ACES (GELI, 2002; GELI at. al., 2003, 2004; AMORIM et. al, 2004; FREITAS, OLIVEIRA et. al, 2003, dentre outros) e o “Teste da Sustentabilidade” da USP. Os resultados estão sendo utilizados para geração de subsídios à política institucional de ambientalização curricular e na proposta do Programa “Univali Sustentável”

Factors associated with the delay in seeking legal abortion for pregnancy resulting from rape

AbstractBackground: about 7% of rape cases in Brazil result in pregnancy. Brazilian  women generally are unaware of the right to legal interruption of pregnancy  after rape and try to end abortion in an unsafe manner or last to request the  procedure. Objective: to analyse factors associated with the time of seeking  legal abortion after rape in a public hospital. Methods: this is an observational,  analytical, and cross-sectional study. Data are from medical records of 1,270  women who complained of rape and have requested legal abortion in a public  hospital in São Paulo between 1994 and 2013. The variables age, education,  race, marital status, religion, form of intimidation, vulnerable condition,  perpetrator of sexual violence, number of perpetrators, and police report were analysed in relation to gestational age, according to multiple multinomial logistic  regression models. Results: the delay in requesting abortion at intermediate  gestational age is associated to when a woman is vulnerable (p=0.015), late  gestational age is associated with the presence of a police report (p=0.029) and 48 marital status as ngle (p=0.05). Be a relative of the aggressor is associated with  both intermediate (p=0.016) and late gestational age (p=0.002). Conclusions:  women without partners, who suffered intimidation with threats, in a vulnerable  condition, who made a police report and, above all, who were raped by relatives,  composed the group who took longer to get the health service.Keywords: sexual violence; rape; unwanted pregnancy; legal abortio

Biological effects of trans, trans-farnesol in Leishmania amazonensis

IntroductionFarnesol, derived from farnesyl pyrophosphate in the sterols biosynthetic pathway, is a molecule with three unsaturations and four possible isomers. Candida albicans predominantly secretes the trans, trans-farnesol (t, t-FOH) isomer, known for its role in regulating the virulence of various fungi species and modulating morphological transition processes. Notably, the evolutionary divergence in sterol biosynthesis between fungi, including Candida albicans, and trypanosomatids resulted in the synthesis of sterols with the ergostane skeleton, distinct from cholesterol. This study aims to assess the impact of exogenously added trans, trans-farnesol on the proliferative ability of Leishmania amazonensis and to identify its presence in the lipid secretome of the parasite.MethodsThe study involved the addition of exogenous trans, trans-farnesol to evaluate its interference with the proliferation of L. amazonensis promastigotes. Proliferation, cell cycle, DNA fragmentation, and mitochondrial functionality were assessed as indicators of the effects of trans, trans-farnesol. Additionally, lipid secretome analysis was conducted, focusing on the detection of trans, trans-farnesol and related products derived from the precursor, farnesyl pyrophosphate. In silico analysis was employed to identify the sequence for the farnesene synthase gene responsible for producing these isoprenoids in the Leishmania genome.ResultsExogenously added trans, trans-farnesol was found to interfere with the proliferation of L. amazonensis promastigotes, inhibiting the cell cycle without causing DNA fragmentation or loss of mitochondrial functionality. Despite the absence of trans, trans-farnesol in the culture supernatant, other products derived from farnesyl pyrophosphate, specifically α-farnesene and β-farnesene, were detected starting on the fourth day of culture, continuing to increase until the tenth day. Furthermore, the identification of the farnesene synthase gene in the Leishmania genome through in silico analysis provided insights into the enzymatic basis of isoprenoid production.DiscussionThe findings collectively offer the first insights into the mechanism of action of farnesol on L. amazonensis. While trans, trans-farnesol was not detected in the lipid secretome, the presence of α-farnesene and β-farnesene suggests alternative pathways or modifications in the isoprenoid metabolism of the parasite. The inhibitory effects on proliferation and cell cycle without inducing DNA fragmentation or mitochondrial dysfunction raise questions about the specific targets and pathways affected by exogenous trans, trans-farnesol. The identification of the farnesene synthase gene provides a molecular basis for understanding the synthesis of related isoprenoids in Leishmania. Further exploration of these mechanisms may contribute to the development of novel therapeutic strategies against Leishmania infections

Dynamics and determinants of SARS-CoV-2 RT-PCR testing on symptomatic individuals attending healthcare centers during 2020 in Bahia, Brazil

RT-PCR testing data provides opportunities to explore regional and individual determinants of test positivity and surveillance infrastructure. Using Generalized Additive Models, we explored 222,515 tests of a random sample of individuals with COVID-19 compatible symptoms in the Brazilian state of Bahia during 2020. We found that age and male gender were the most significant determinants of test positivity. There was evidence of an unequal impact among socio-demographic strata, with higher positivity among those living in areas with low education levels during the first epidemic wave, followed by those living in areas with higher education levels in the second wave. Our estimated probability of testing positive after symptom onset corroborates previous reports that the probability decreases with time, more than halving by about two weeks and converging to zero by three weeks. Test positivity rates generally followed state-level reported cases, and while a single laboratory performed ~90% of tests covering ~99% of the state's area, test turn-around time generally remained below four days. This testing effort is a testimony to the Bahian surveillance capacity during public health emergencies, as previously witnessed during the recent Zika and Yellow Fever outbreaks

Health-related quality of life in patients with type 1 diabetes mellitus in the different geographical regions of Brazil : data from the Brazilian Type 1 Diabetes Study Group

Background: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical characteristics of patients with T1DM in Brazil, a country of continental proportions, as well as investigate which variables could influence the HRQoL of these individuals and contribute to these regional disparities. Methods: This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG), by analyzing EuroQol scores from 3005 participants with T1DM, in 28 public clinics, among all geographical regions of Brazil. Data on demography, economic status, chronic complications, glycemic control and lipid profile were also collected. Results: We have found that the North-Northeast region presents a higher index in the assessment of the overall health status (EQ-VAS) compared to the Southeast (74.6 ± 30 and 70.4 ± 19, respectively; p < 0.05). In addition, North- Northeast presented a lower frequency of self-reported anxiety-depression compared to all regions of the country (North-Northeast: 1.53 ± 0.6; Southeast: 1.65 ± 0.7; South: 1.72 ± 0.7; Midwest: 1.67 ± 0.7; p < 0.05). These findings could not be entirely explained by the HbA1c levels or the other variables examined. Conclusions: Our study points to the existence of additional factors not yet evaluated that could be determinant in the HRQoL of people with T1DM and contribute to these regional disparities