102 research outputs found

    How do women living with HIV experience menopause? Menopausal symptoms, anxiety and depression according to reproductive age in a multicenter cohort

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    CatedresBackground: To estimate the prevalence and severity of menopausal symptoms and anxiety/depression and to assess the differences according to menopausal status among women living with HIV aged 45-60 years from the cohort of Spanish HIV/AIDS Research Network (CoRIS). Methods: Women were interviewed by phone between September 2017 and December 2018 to determine whether they had experienced menopausal symptoms and anxiety/depression. The Menopause Rating Scale was used to evaluate the prevalence and severity of symptoms related to menopause in three subscales: somatic, psychologic and urogenital; and the 4-item Patient Health Questionnaire was used for anxiety/depression. Logistic regression models were used to estimate odds ratios (ORs) of association between menopausal status, and other potential risk factors, the presence and severity of somatic, psychological and urogenital symptoms and of anxiety/depression. Results: Of 251 women included, 137 (54.6%) were post-, 70 (27.9%) peri- and 44 (17.5%) pre-menopausal, respectively. Median age of onset menopause was 48 years (IQR 45-50). The proportions of pre-, peri- and post-menopausal women who had experienced any menopausal symptoms were 45.5%, 60.0% and 66.4%, respectively. Both peri- and post-menopause were associated with a higher likelihood of having somatic symptoms (aOR 3.01; 95% CI 1.38-6.55 and 2.63; 1.44-4.81, respectively), while post-menopause increased the likelihood of having psychological (2.16; 1.13-4.14) and urogenital symptoms (2.54; 1.42-4.85). By other hand, post-menopausal women had a statistically significant five-fold increase in the likelihood of presenting severe urogenital symptoms than pre-menopausal women (4.90; 1.74-13.84). No significant differences by menopausal status were found for anxiety/depression. Joint/muscle problems, exhaustion and sleeping disorders were the most commonly reported symptoms among all women. Differences in the prevalences of vaginal dryness (p = 0.002), joint/muscle complaints (p = 0.032), and sweating/flush (p = 0.032) were found among the three groups. Conclusions: Women living with HIV experienced a wide variety of menopausal symptoms, some of them initiated before women had any menstrual irregularity. We found a higher likelihood of somatic symptoms in peri- and post-menopausal women, while a higher likelihood of psychological and urogenital symptoms was found in post-menopausal women. Most somatic symptoms were of low or moderate severity, probably due to the good clinical and immunological situation of these women

    Intelligent software and tecnological convergence

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    La Facultad de Ingeniería de la Universidad Católica de Colombia, conforme al factor calidad y considerando las tendencias de vanguardia en el ámbito de innovación en ingeniería, desarrollo en la segunda parte de esté congreso, el software inteligente y convergencia tecnológica, Raspberry PI dispositivo apuntador utilizando Open CV, Procesar imágenes identificando maleza en cultivos, también plataformas tecnológicas en enseñanza en la automatización industrial, implementación de JAX-RS, arquitectura soportada en sistemas inteligentes con control de aprendizaje interactivo, modelado del efecto de alineación estática en prótesis transtibiales en redes neuronales, desarrollo e implementación robótica industrial, modelos en la predicción de pérdidas de propagación de ondas electromagnéticas por celular, además, sistemas de autocuidado para el monitoreo en la infraestructura tecnológica distribuida, modelado de elementos 3D trabajos basados en redes difusas, lógica modal de comunicación en sistemas multiagentes, sistemas de adquisición de datos en procesos agroindustriales, herramientas diagnostica en ergonomía aplicada en puesto de trabajo uso de música colombiana en estudiantes colombianos con BCI, sin olvidar, el método automático en morfología digital de hojas tropicales en Colombia, simulación de radiopropagación en red LTE en banda de dividendo digital, desarrollo de plataformas con inteligencia artificial, Cloud computing una oportunidad para las mipymes en Colombia, ontología en la construcción de indicadores en un sistema de soporte con identificador de vulnerabilidad, Nano y biotecnología para generar energía, modelo de optimización del programa para intercambio de riñones, adicionalmente, la tendencia en redes y banda ancha, aplicación de algoritmo genético en nuevos productos, control de maleza en la productividad de cultivo, tecnología de la información para la asignación de turnos de enfermería, antenas fractales en nanoestructuradas, y por último, Brokering servicios multiplataforma con accesibilidad de profesores y estudiantes a contenido educativo gratis. (Redacción propia).II. Software Inteligente y Convergencia Tecnológica. Raspberry Pi como dispositivo apuntador utilizando OpenCV e integrales proyectivas. Procesamiento de imágenes para identificación de malezas en cultivos. Plataforma tecnológica para la enseñanza y la simulación de procesos en automatización industrial. Comparación de implementaciones JAX-RS. Arquitectura distribuida soportada en sistemas inteligentes difusos para el seguimiento del aprendizaje en entornos interactivos. Modelado del efecto de la alineación estática de prótesis transtibiales aplicando redes neuronales. Diseño, desarrollo e implementación de la robótica industrial. Modelos para la predicción de pérdidas de propagación de ondas electromagnéticas en interiores en frecuencias de comunicación celular. Sistema de autocuidado basado en un enfoque de multiagentes para el monitoreo y la corrección de problemas en una infraestructura tecnológica distribuida. Modelado de elementos 3D: de Solidworks a Matlab. Construcción de activos de trabajo basados en conocimiento con redes difusas. Lógica modal en la formalización de comunicación en sistemas multiagentes. Sistemas de adquisición de datos en redes convergentes aplicados en procesos de agroindustria. Herramienta diagnóstica para la evaluación ergonómica del puesto de trabajo. El uso de música colombiana para evaluar el sentido de pertenencia en estudiantes colombianos con BCI. Un método automático para la caracterización morfológica digital de hojas tropicales de Colombia. Simulación de radiopropagación para el diseño de una red LTE en la banda del dividendo digital. Marco conceptual para el desarrollo de plataformas de enseñanza y aprendizaje basadas en inteligencia artificial. Cloud computing, una oportunidad para apalancar la cadena de valor de las mipymes en Colombia. Ontología para la construcción de indicadores de un sistema de soporte a las decisiones para la identificación del índice de vulnerabilidad territorial. Nano y biotecnología para la generación de energía (proyectos Universidad Católica). Modelo de optimización del programa de intercambio de riñones con múltiples etapas. Tendencias en redes y servicios de banda ancha. Aplicación de algoritmos genéticos al diseño de nuevos productos. El control de malezas como elemento significativo en la productividad de cultivos. Tecnologías de la información para resolver el problema de asignación de turnos de enfermería. Antenas fractales nanoestructuradas y estudiantes a contenidos educativos gratuitos

    Measurement of C ⁣PC\!P violation observables in D+KK+π+D^+\rightarrow K^-K^+\pi^+ decays

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    International audienceA search for violation of the charge-parity C ⁣PC\!P symmetry in the D+KK+π+D^+\rightarrow K^-K^+\pi^+ decay is presented, with proton-proton collision data corresponding to an integrated luminosity of 5.4 fb1^{-1}, collected at a center-of-mass energy of 1313 TeV with the LHCb detector. A novel model-independent technique is used to compare the D+D^+ and DD^- phase-space distributions, with instrumental asymmetries subtracted using the Ds+KK+π+D^+_{s}\rightarrow K^-K^+\pi^+ decay as a control channel. The pp-value for the hypothesis of C ⁣PC\!P conservation is 8.1%8.1\%. The C ⁣PC\!P asymmetry observables AC ⁣PSϕπ+=(0.95±0.43stat±0.26syst)×103A_{C\!P|S}^{\phi\pi^+} = (0.95 \pm 0.43_{stat} \pm 0.26_{syst})\times 10^{-3} and AC ⁣PSK0K+=(0.26±0.56stat±0.18syst)×103A_{C\!P|S}^{\overline{K}^{*0}K^+} = (-0.26 \pm 0.56_{ stat} \pm 0.18_{syst})\times 10^{-3} are also measured. These results show no evidence of C ⁣PC\!P violation and represent the most sensitive search performed through the phase space of a multibody decay

    First determination of the spin-parity of Ξc(3055)+,0{\Xi}_{c}(3055)^{+,0} baryons

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    International audienceThe Ξb0()Ξc(3055)+(0)(D+(0)Λ)π{{\Xi}_{b}^{0(-)}\to{\Xi}_{c}(3055)^{+(0)}(\to D^{+(0)}{\Lambda}){\pi}^{-}} decay chains are observed, and the spin-parity of Ξc(3055)+(0){\Xi}_{c}(3055)^{+(0)} baryons is determined for the first time. The measurement is performed using proton-proton collision data at a center-of-mass energy of s=13TeV\sqrt{s}=13\,\text{TeV}, corresponding to an integrated luminosity of 5.4fb15.4\,\text{fb}^{-1}, recorded by the~LHCb\text{LHCb} experiment between 2016 and 2018. The spin-parity of the Ξc(3055)+(0){\Xi}_{c}(3055)^{+(0)} baryons is determined to be 3/2+3/2^{+} with a significance of more than 6.5σ6.5\sigma (3.5σ3.5\sigma) compared to all other tested hypotheses. The up-down asymmetries of the Ξb0()Ξc(3055)+(0)π{{\Xi}_{b}^{0(-)}\to{\Xi}_{c}(3055)^{+(0)}{\pi}^{-}} transitions are measured to be 0.92±0.10±0.05-0.92\pm0.10\pm0.05 (0.92±0.16±0.22-0.92\pm0.16\pm0.22), consistent with maximal parity violation, where the first uncertainty is statistical and the second is systematic. These results support the hypothesis that the Ξc(3055)+(0){\Xi}_{c}(3055)^{+(0)} baryons correspond to the first DD-wave λ\lambda-mode excitation of the Ξc{\Xi}_{c} flavor triplet

    Analysis of Λb0pKμ+μ\it{\Lambda}^\mathrm{0}_b \rightarrow pK^-\mu^+\mu^- decays

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    International audienceThe differential branching fraction and angular coefficients of \ensuremath{\it{\Lambda}^\mathrm{0}_b \rightarrow pK^-\mu^+\mu^-}\xspace decays are measured in bins of the dimuon mass squared and dihadron mass. The analysis is performed using a data set corresponding to 9\aunit{fb}^{-1} of integrated luminosity collected with the \mbox{LHCb} detector between 2011 and 2018. The data are consistent with receiving contributions from a mixture of Λ\it{\Lambda} resonances with different spin-parity quantum numbers. The angular coefficients show a pattern of vector--axial vector interference that is a characteristic of the type of flavour-changing neutral-current transition relevant for these decays

    Test of lepton flavour universality with Bs0ϕ+B_s^0 \rightarrow \phi \ell^+\ell^- decays

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    International audienceLepton flavour universality in rare bsb\rightarrow s transitions is tested for the first time using Bs0B_s^0 meson decays. The measurements are performed using pppp collision data collected by the LHCb experiment between 2011 and 2018, corresponding to a total integrated luminosity of 9fb1\,{\rm fb}^{-1}. Branching fraction ratios between the Bs0ϕe+eB_s^0 \rightarrow \phi e^+e^- and Bs0ϕμ+μB_s^0 \rightarrow \phi \mu^+\mu^- decays are measured in three regions of dilepton mass squared, q2q^2, with 0.1<q2<1.10.1 < q^2 < 1.1, 1.1<q2<6.01.1 < q^2 < 6.0, and 15<q2<19GeV2/c415 < q^2 < 19\,{\rm GeV}^2/c^4. The results agree with the Standard Model expectation of lepton flavour universality

    First determination of the spin-parity of Ξc(3055)+,0{\Xi}_{c}(3055)^{+,0} baryons

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    International audienceThe Ξb0()Ξc(3055)+(0)(D+(0)Λ)π{{\Xi}_{b}^{0(-)}\to{\Xi}_{c}(3055)^{+(0)}(\to D^{+(0)}{\Lambda}){\pi}^{-}} decay chains are observed, and the spin-parity of Ξc(3055)+(0){\Xi}_{c}(3055)^{+(0)} baryons is determined for the first time. The measurement is performed using proton-proton collision data at a center-of-mass energy of s=13TeV\sqrt{s}=13\,\text{TeV}, corresponding to an integrated luminosity of 5.4fb15.4\,\text{fb}^{-1}, recorded by the~LHCb\text{LHCb} experiment between 2016 and 2018. The spin-parity of the Ξc(3055)+(0){\Xi}_{c}(3055)^{+(0)} baryons is determined to be 3/2+3/2^{+} with a significance of more than 6.5σ6.5\sigma (3.5σ3.5\sigma) compared to all other tested hypotheses. The up-down asymmetries of the Ξb0()Ξc(3055)+(0)π{{\Xi}_{b}^{0(-)}\to{\Xi}_{c}(3055)^{+(0)}{\pi}^{-}} transitions are measured to be 0.92±0.10±0.05-0.92\pm0.10\pm0.05 (0.92±0.16±0.22-0.92\pm0.16\pm0.22), consistent with maximal parity violation, where the first uncertainty is statistical and the second is systematic. These results support the hypothesis that the Ξc(3055)+(0){\Xi}_{c}(3055)^{+(0)} baryons correspond to the first DD-wave λ\lambda-mode excitation of the Ξc{\Xi}_{c} flavor triplet

    Measurement of CPCP violation in B0D+D{B^0}\rightarrow{D^{+}D^{-}} and Bs0Ds+Ds{B^{0}_{s}}\rightarrow{D^{+}_{s}D^{-}_{s}} decays

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    International audienceA time-dependent, flavour-tagged measurement of CPCP violation is performed with B0D+D{B^0}\rightarrow{D^{+}D^{-}} and Bs0Ds+Ds{B^{0}_{s}}\rightarrow{D^{+}_{s}D^{-}_{s}} decays, using data collected by the LHCb detector in proton-proton collisions at a centre-of-mass energy of 13 TeV corresponding to an integrated luminosity of 6 fb1^{-1}. In B0D+D{B^0}\rightarrow{D^{+}D^{-}} decays the CPCP-violation parameters are measured to be \begin{align} S_{D^{+}D^{-}} & = -0.552 \pm 0.100\,\text{(stat)} \pm 0.010\,\text{(syst)}, \nonumber \newline C_{D^{+}D^{-}} & = \phantom{-}0.128 \pm0.103\,\text{(stat)} \pm 0.010\,\text{(syst)}. \nonumber \end{align} In Bs0Ds+DsB^{0}_{s} \rightarrow D^{+}_{s}D^{-}_{s} decays the CPCP-violating parameter formulation in terms of ϕs\phi_{s} and λ|\lambda| results in \begin{align} \phi_{s} & = -0.086 \pm 0.106 \,\text{(stat)} \pm 0.028\,\text{(syst)} \,\text{rad}, \nonumber \newline |\lambda_{D^{+}_{s}D^{-}_{s}}| & = \phantom{-}1.145 \pm 0.126\,\text{(stat)} \pm 0.031\,\text{(syst)}. \nonumber \end{align} These results represent the most precise single measurement of the CPCP-violation parameters in their respective channels. For the first time in a single measurement, CPCP symmetry is observed to be violated in B0D+D{B^0}\rightarrow{D^{+}D^{-}} decays with a significance exceeding six standard deviations

    Measurement of C ⁣PC\!P violation observables in D+KK+π+D^+\rightarrow K^-K^+\pi^+ decays

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    International audienceA search for violation of the charge-parity C ⁣PC\!P symmetry in the D+KK+π+D^+\rightarrow K^-K^+\pi^+ decay is presented, with proton-proton collision data corresponding to an integrated luminosity of 5.4 fb1^{-1}, collected at a center-of-mass energy of 1313 TeV with the LHCb detector. A novel model-independent technique is used to compare the D+D^+ and DD^- phase-space distributions, with instrumental asymmetries subtracted using the Ds+KK+π+D^+_{s}\rightarrow K^-K^+\pi^+ decay as a control channel. The pp-value for the hypothesis of C ⁣PC\!P conservation is 8.1%8.1\%. The C ⁣PC\!P asymmetry observables AC ⁣PSϕπ+=(0.95±0.43stat±0.26syst)×103A_{C\!P|S}^{\phi\pi^+} = (0.95 \pm 0.43_{stat} \pm 0.26_{syst})\times 10^{-3} and AC ⁣PSK0K+=(0.26±0.56stat±0.18syst)×103A_{C\!P|S}^{\overline{K}^{*0}K^+} = (-0.26 \pm 0.56_{ stat} \pm 0.18_{syst})\times 10^{-3} are also measured. These results show no evidence of C ⁣PC\!P violation and represent the most sensitive search performed through the phase space of a multibody decay
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