Análise dos significados construídos pelos estudantes sobre a simulaçãocomputacional do interferômetro de Mach-Zehnder no ensino médio tecnológico

Neste trabalho investigamos os significados construídos sobre o laboratório de simulação computacional, utilizando a simulação do interferômetro de Mach-Zehnder (IMZ), por estudantes da educação básica tecnológica de três turmas do ensino médio técnico integrado do Instituto Federal de Educação, Ciência e Tecnologia da Bahia nos Campus de Salvador e Camaçari. Realizamos filmagens durante as aulas sobre a dualidade da luz no ensino médio como forma de introduzir os conceitos de física quântica e através da metodologia de análise discursiva textual interpretamos os significados construídos pelos estudantes. Por fim, apresentamos os significados construídos na atividade e apontamos potencialidades e limitações desta quando realizada isoladamente sem o laboratório convencional

Atualização em Cirurgia Neoplásica do Tórace

O A. traça as linhas de conduta seguida na Clínica de Tórace do Instituto Nacional de Câncer, sob sua chefia, focalizando a técnica cirúrgica, diagnóstico, pré e post-operatório. Mostra em cada setôr, sua experiência pessoal, como variante apenas da técnica de Svveet e Pach. Defende a via esquerda nas Toracotomias para cirurgia do esôfago. Insiste em não perder tempo, procurando-se o diagnóstico etiológico, quando se tem na toracotomia explorada o melhor e mais eficaz meio, através a biópsia pré-operatória. Só usa a Radioterapia e a Quimioterapia para os casos inoperáveis, em que não foi possível a exérese completa ou ainda, nas recídicas

Parâmetros reprodutivos após indução de estro com diferentes intervalos de permanência do dispositivo vaginal em cabras Toggenburg acíclicas.

Resumo: Este estudo objetivou avaliar o comportamento sexual e a dinâmica ovulatória de cabras da raça Toggenburg após a indução do estro com dispositivo intravaginal de progesterona durante seis, nove e 12 dias de permanência. No momento da inserção do dispositivo e 24 horas antes da retirada do dispositivo, foi administrado 5mg de dinoprost e 200UI de eCG, respectivamente. A dinâmica ovulatória foi acompanhada por ultrassonografia a cada oito horas, enquanto o estro foi observado a cada 12 horas. Todas as cabras apresentaram estro. O intervalo da retirada do dispositivo ao início do estro foi de 29,5 ± 9,6 para G6dias; 34,0 ± 6,0 e 32,4 ± 7,7h, G9dias e G12dias, respectivamente. Igualmente, foi encontrada diferença (P0,05). Todos os protocolos foram eficientes em induzir o estro sincronizado em cabras da raça Toggenburg, trabalhando em conjunto com a eficiência reprodutiva e produtiva desses animais. [Reproductive parameters after induction of estrus with different ranges of the vaginal device in acyclic Toggenburg goats]. Abstract: This study aimed to evaluate the sexual behavior and the ovulatory dynamics of Toggenburg goats after induction of synchronized estrus by an intravaginal progesterone device for six, nine and twelve days. At the device insertion and 24 h before the device removal, 5mg of dinoprost and 200 UI of eCG was administered, respectively. The ovulatory dynamics was assessed by ultrasound every 8 h, while the sexual behavior was observed every 12 h. All goats showed estrus. The intervals from device removal to estrus were 29.5 ± 9.7, 34.0 ± 6.0 and 32.4 ± 7.7h to G6days, G9days and G12days, respectively. Iqually, it was found difference (P0.05). All treatments were effective for the induction of synchronized estrus in Toggenburg goats, working jointly with the reproductive and productive efficiency of these animals

Risk of transmission of caprine arthritis - encephalitis virus (CAEV) through embryos transfer from naturally infected donors.

The caprine arthritis encephalitis is an important viral and most important infectious disease in dairy goats. The infection causes several economic losses. The high prevalence CAEV infection in countries that export goat genetics generated a great concern, since the international trade might introduce the virus in different countries by embryo transfer spreading the disease. Thus, the aim of the study was to evaluate the risk of caprine arthritis encephalitis virus (CAEV) transmission by in vivo embryos from naturally infected donors. Thus, results of the present study showed no transmission of CAEV by embryos originated from CAEV positive donors by embryos from transcervical method washing treatment. [Risco de transmissão o vírus da artrite encefalite caprina (CAEV) através de embriões oriundos de cabras sorologiamente positivas].Edição dos anais do XXII Congresso Brasileiro de Reprodução Animal (CBRA), Santos, SP, Brasil, maio 2017

Capital Social e suas Implicações para o Estudo das Organizações

Em que pese sua crescente importância para vários ramos das ciências sociais, o conceito de capital social não vem merecendo grande atenção por parte dos estudiosos das organizações. No entanto, algumas de suas categorias analíticas - como as hipóteses subjacentes à capacidade dos grupos sociais de interagir, criar redes, cooperar e empreender ações coletivas - podem ser extremamente úteis nesse campo. Particularmente agora, quando os desafios advindos com a globalização e a introdução de novas tecnologias de informação levam ao questionamento de modelos organizacionais tradicionais - com ênfase em hierarquia, presença de mecanismos formais de controle, fronteiras organizacionais bem delimitadas – e trazem a exigência de novas alternativas. O propósito deste trabalho é o de investigar as origens e repercussões do conceito de capital social na literatura corrente e suas possibilidades de aplicação nos estudos organizacionais. Pretende-se, com isso, fornecer elementos de reflexão que estimulem estudos e pesquisas sobre as implicações do capital social e o desenvolvimento organizacional no Brasil

Strategies to Improve the Barrier and Mechanical Properties of Pectin Films for Food Packaging: Comparing Nanocomposites with Bilayers

2020.04441.BD SFRH/BD/144346/2019 UIDB/50006/2020 UIDP/50006/2020 UIDB/04077/2020 UIDP/04077/2020 UIDB /00100/2020Traditional food packaging systems help reduce food wastage, but they also produce environmental impacts when not properly disposed of. Bio-based polymers are a promising solution to overcome these impacts, but they have poor barrier and mechanical properties. This work evaluates two strategies to improve these properties in pectin films: the incorporation of cellulose nanocrystals (CNC) or sodium montmorillonite (MMT) nanoparticles, and an additional layer of chitosan (i.e., a bilayer film). The bionanocomposites and bilayer films were characterized in terms of optical, morphological, hygroscopic, mechanical and barrier properties. The inclusion of the nanofillers in the polymer reduced the water vapor permeability and the hydrophilicity of the films without compromising their visual properties (i.e., their transparency). However, the nanoparticles did not substantially improve the mechanical properties of the bionanocomposites. Regarding the bilayer films, FTIR and contact angle studies revealed no surface and/or chemical modifications, confirming only physical coating/lamination between the two polymers. These bilayer films exhibited a dense homogenous structure, with intermediate optical and hygroscopic properties. An additional layer of chitosan did not improve the mechanical, water vapor and oxygen barrier properties of the pectin films. However, this additional layer made the material more hydrophobic, which may play an important role in the application of pectin as a food packaging material.publishersversionpublishe

Planejamento do desenvolvimento tecnológico na Petrobrás

O artigo apresenta as motivações que levaram à constatação da necessidade de maior atenção ao planejamento de longo prazo no CENPES. Discute tambem a metodologia seguida na elaboração do Plano Diretor, suas principals conclusões e consequências no planejamento da evolução do desenvolvimento tecnológico na PETROBRÁS

Trypanosoma cruzi Adjuvants Potentiate T Cell-Mediated Immunity Induced by a NY-ESO-1 Based Antitumor Vaccine

Immunological adjuvants that induce T cell-mediate immunity (TCMI) with the least side effects are needed for the development of human vaccines. Glycoinositolphospholipids (GIPL) and CpGs oligodeoxynucleotides (CpG ODNs) derived from the protozoa parasite Trypanosoma cruzi induce potent pro-inflammatory reaction through activation of Toll-Like Receptor (TLR)4 and TLR9, respectively. Here, using mouse models, we tested the T. cruzi derived TLR agonists as immunological adjuvants in an antitumor vaccine. For comparison, we used well-established TLR agonists, such as the bacterial derived monophosphoryl lipid A (MPL), lipopeptide (Pam3Cys), and CpG ODN. All tested TLR agonists were comparable to induce antibody responses, whereas significant differences were noticed in their ability to elicit CD4+ T and CD8+ T cell responses. In particular, both GIPLs (GTH, and GY) and CpG ODNs (B344, B297 and B128) derived from T. cruzi elicited interferon-gamma (IFN-γ) production by CD4+ T cells. On the other hand, the parasite derived CpG ODNs, but not GIPLs, elicited a potent IFN-γ response by CD8+ T lymphocytes. The side effects were also evaluated by local pain (hypernociception). The intensity of hypernociception induced by vaccination was alleviated by administration of an analgesic drug without affecting protective immunity. Finally, the level of protective immunity against the NY-ESO-1 expressing melanoma was associated with the magnitude of both CD4+ T and CD8+ T cell responses elicited by a specific immunological adjuvant

Cold coffee seeds storage with different water content.

Coffee seeds are classified as intermediate because they have low tolerance to desiccation and low longevity. Consequently, moisture control and storage conditions are important factors in maintaining the physiological quality of these seeds. Thus, the objective in this work was to evaluate the water content effect on coffee seed longevity. Seeds of five Coffea arabica cultivars from the 2016/2017 crop were used. Part of the harvested seeds was dried in the shade until reach 12% moisture and the other part did not go through drying process, remaining with 40% water content. The seeds were stored in a cold chamber at 10 oC for a period of nine months, and the physiological quality was evaluated every three months by germination, root protrusion, seedlings with expanded cotyledonary leaves, seedling dry mass and enzymatic analysis of catalase enzymes and superoxide dismutase. Regardless of the cultivar, wet seeds coffee storage provides better maintenance of physiological quality for up to nine months. Seedling vigor is reduced throughout the storage period, regardless of seed water content

Tinnitus emerging in the context of a COVID-19 infection seems not to differ in its characteristics from tinnitus unrelated to COVID-19

Background and aim: COVID-19 is a respiratory disease caused by the new coronavirus SARS-CoV-2, for which the first cases were reported in China, by December 2019. The spectrum of clinical presentations is wide, ranging from asymptomatic cases to a severe acute respiratory syndrome, sometimes with multiple systems involvement. Viral infections, including those related to respiratory virus, may cause hearing loss and, by extent, considering its pathophysiology, tinnitus. A systematic review on inner ear related symptoms in patients with COVID-19 reported 4.5% occurrence rate of tinnitus, with high variance of prevalence between the studies. Our aim is to further explore the relationship between COVID-19 and tinnitus. For this purpose we analyzed a sample of people who had suffered from a COVID-19 infection in the city of Volta Redonda, Brazil. In detail, we compared those with new onset tinnitus during or after the COVID-19 infection with those without tinnitus and those with tinnitus onset before the COVID-19 infection. Methods: Fifty-seven patients over 18 years old and previously diagnosed with COVID-19 confirmed by a RT-PCR test were included. Patients were subdivided in three groups: no tinnitus (NT), tinnitus that already existed before COVID-19 (chronic tinnitus, CT) and tinnitus that arose during or after COVID-19 (post-COVID-19 tinnitus, PCT). Data concerning COVID-19 symptoms, drugs prescribed for COVID-19, tinnitus characteristics, comorbidities and other otological symptoms were collected. For all the patients, tonal audiometry and otoacoustic emissions were performed. Tinnitus patients fulfilled the Tinnitus Handicap Inventory (THI) and visual-analog scales (VAS) for loudness and distress. Patients with CT answered a simple question about the worsening of their tinnitus after COVID-19. Results: PCT was reported by 19.3% of the patients, while 22.8% reported CT. No statistical difference was found between CT and PCT concerning hearing function, tinnitus characteristics and tinnitus distress. There was also no statistically significant difference between PCT and NT with respect to COVID-19 symptoms and pharmacological COVID-19 treatment. Patients with CT reported worsening of their tinnitus after COVID-19. Conclusion: As with other viral infections, inner ear symptoms may be associated with COVID-19. In our sample patients with tinnitus onset before COVID-19 and those with tinnitus onset during or after COVID-19 did not differ significantly in their clinical characteristics and their hearing function, suggesting that tinnitus occurring in the context of a COVID-19 infection is not related to a unique pathophysiological mechanism. The comparison of COVID-19 patients, who developed tinnitus with those who did not develop tinnitus did not reveal any differences in COVID-19 symptoms or COVID-19 treatment. Thus, there was no hint, that a specific expression of COVID-19 is closely related to post COVID-19 tinnitus onset. Although some drugs used to treat tinnitus are known to damage the inner ear cells (especially hydroxychloroquine), we did not see any relationship between the intake of these drugs and tinnitus onset, eventually due to the short prescription time and low doses. Among those patients who had tinnitus before COVID-19 30,8% reported worsening after COVID-19. Overall, tinnitus emerging in the context of a COVID-19 infection seems not to differ from tinnitus unrelated to COVID-19. For further exploring the relationship of tinnitus and COVID-19, large population based studies are warranted