146 research outputs found
Polariton condensation and lasing in optical microcavities - the decoherence driven crossover
We explore the behaviour of a system which consists of a photon mode dipole
coupled to a medium of two-level oscillators in a microcavity in the presence
of decoherence. We consider two types of decoherence processes which are
analogous to magnetic and non-magnetic impurities in superconductors. We study
different phases of this system as the decoherence strength and the excitation
density is changed. For a low decoherence we obtain a polariton condensate with
comparable excitonic and photonic parts at low densities and a BCS-like state
with bigger photon component due to the fermionic phase space filling effect at
high densities. In both cases there is a large gap in the density of states. As
the decoherence is increased the gap is broadened and suppressed, resulting in
a gapless condensate and finally a suppression of the coherence in a low
density regime and a laser at high density limit. A crossover between these
regimes is studied in a self-consistent way analogous to the Abrikosov and
Gor'kov theory of gapless superconductivity.Comment: 17 pages, 8 figures, submitted to PR
A probabilistic model for gene content evolution with duplication, loss, and horizontal transfer
We introduce a Markov model for the evolution of a gene family along a
phylogeny. The model includes parameters for the rates of horizontal gene
transfer, gene duplication, and gene loss, in addition to branch lengths in the
phylogeny. The likelihood for the changes in the size of a gene family across
different organisms can be calculated in O(N+hM^2) time and O(N+M^2) space,
where N is the number of organisms, is the height of the phylogeny, and M
is the sum of family sizes. We apply the model to the evolution of gene content
in Preoteobacteria using the gene families in the COG (Clusters of Orthologous
Groups) database
Infrastructure for Detector Research and Development towards the International Linear Collider
The EUDET-project was launched to create an infrastructure for developing and
testing new and advanced detector technologies to be used at a future linear
collider. The aim was to make possible experimentation and analysis of data for
institutes, which otherwise could not be realized due to lack of resources. The
infrastructure comprised an analysis and software network, and instrumentation
infrastructures for tracking detectors as well as for calorimetry.Comment: 54 pages, 48 picture
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
The current wealth of genomic variation data identified at nucleotide level presents the challenge of understanding by which mechanisms amino acid variation affects cellular processes. These effects may manifest as distinct phenotypic differences between individuals or result in the development of disease. Physical interactions between molecules are the linking steps underlying most, if not all, cellular processes. Understanding the effects that sequence variation has on a molecule's interactions is a key step towards connecting mechanistic characterization of nonsynonymous variation to phenotype. We present an open access resource created over 14 years by IMEx database curators, featuring 28,000 annotations describing the effect of small sequence changes on physical protein interactions. We describe how this resource was built, the formats in which the data is provided and offer a descriptive analysis of the data set. The data set is publicly available through the IntAct website and is enhanced with every monthly release
Avaliação da silagem de capim papuã (Brachiaria plantaginea) por meio do desempenho de bezerros de corte confinados
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
Interindividual clinical variability in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is vast. We report that at least 101 of 987 patients with life-threatening coronavirus disease 2019 (COVID-19) pneumonia had neutralizing immunoglobulin G (IgG) autoantibodies (auto-Abs) against interferon-w (IFN-w) (13 patients), against the 13 types of IFN-a (36), or against both (52) at the onset of critical disease; a few also had auto-Abs against the other three type I IFNs. The auto-Abs neutralize the ability of the corresponding type I IFNs to block SARS-CoV-2 infection in vitro. These auto-Abs were not found in 663 individuals with asymptomatic or mild SARS-CoV-2 infection and were present in only 4 of 1227 healthy individuals. Patients with auto-Abs were aged 25 to 87 years and 95 of the 101 were men. A B cell autoimmune phenocopy of inborn errors of type I IFN immunity accounts for life-threatening COVID-19 pneumonia in at least 2.6% of women and 12.5% of men
Perfil de suscetibilidade antimicrobiana e presença do gene vapA em Rhodococcus equi de origem humana, ambiental e equina
Caratteristiche di un impianto di depurazione dei liquami di una industria conserviera animale e suoi effetti sul corso d'acqua ricevente
vengono prese inconsiderazione le caratteristiche e l'efficienza di un moderno impianto di depurazione recentemente installato presso una industria alimentare operante nel settore conserve animali per iil trattamento dei liquami provenienti dall'insutrai con annesso mattatoio e dalla porcilaia prima della loro immissione nell'altto corso del fiume Chienti. Dalle determinazioni effettuate nei mesi febbraio-marzo 1973 e nel mese di luglio dello stesso anni, è risultato un buon funzionamento dell'impianto con una riduzione del carico organico di oltre il 90%; ciò nonostante il fiume, soprattutto nel periodo estivo, sembra risentire, anche se in maniera non eccessiva, del carico inquinante immessovi
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