Mondor's disease as a complication in breast surgery in a male patient. The first ever reported case in literature

Mondor's disease (MD) is an uncommon clinical condition characterized by thrombophlebitis of the superficial veins of the anterolateral thoracoabdominal wall. In this paper we present the first ever reported case of Mondor's disease in male patient after surgical correction of gynecomastia with liposuction assisted skin sparing adenectomy

Gene pathway development in human epicardial adipose tissue during early life

Studies in rodents and newborn humans demonstrate the influence of brown adipose tissue (BAT) in temperature control and energy balance and a critical role in the regulation of body weight. Here, we obtained samples of epicardial adipose tissue (EAT) from neonates, infants, and children in order to evaluate changes in their transcriptional landscape by applying a systems biology approach. Surprisingly, these analyses revealed that the transition to infancy is a critical stage for changes in the morphology of EAT and is reflected in unique gene expression patterns of a substantial proportion of thermogenic gene transcripts (~10%). Our results also indicated that the pattern of gene expression represents a distinct developmental stage, even after the rebound in abundance of thermogenic genes in later childhood. Using weighted gene coexpression network analyses, we found precise anthropometric-specific correlations with changes in gene expression and the decline of thermogenic capacity within EAT. In addition, these results indicate a sequential order of transcriptional events affecting cellular pathways, which could potentially explain the variation in the amount, or activity, of BAT in adulthood. Together, these results provide a resource to elucidate gene regulatory mechanisms underlying the progressive development of BAT during early life

Bilateral Remote Ischemic Conditioning in Children:a two-center, double-blind, randomized controlled trial in young children undergoing cardiac surgery

Objective: The study objective was to determine whether adequately delivered bilateral remote ischemic preconditioning is cardioprotective in young children undergoing surgery for 2 common congenital heart defects with or without cyanosis.Methods: We performed a prospective, double-blind, randomized controlled trial at 2 centers in the United Kingdom. Children aged 3 to 36 months undergoing tetralogy of Fallot repair or ventricular septal defect closure were randomized 1:1 to receive bilateral preconditioning or sham intervention. Participants were followed up until hospital discharge or 30 days. The primary outcome was area under the curve for high-sensitivity troponin-T in the first 24 hours after surgery, analyzed by intention-to-treat. Right atrial biopsies were obtained in selected participants.Results: Between October 2016 and December 2020, 120 eligible children were randomized to receive bilateral preconditioning (n = 60) or sham intervention (n = 60). The primary outcome, area under the curve for high-sensitivity troponin-T, was higher in the preconditioning group (mean: 70.0 ± 50.9 μg/L/h, n = 56) than in controls (mean: 55.6 ± 30.1 μg/L/h, n = 58) (mean difference, 13.2 μg/L/h; 95% CI, 0.5-25.8; P = .04). Subgroup analyses did not show a differential treatment effect by oxygen saturations (pinteraction = .25), but there was evidence of a differential effect by underlying defect (pinteraction = .04). Secondary outcomes and myocardial metabolism, quantified in atrial biopsies, were not different between randomized groups.Conclusions: Bilateral remote ischemic preconditioning does not attenuate myocardial injury in children undergoing surgical repair for congenital heart defects, and there was evidence of potential harm in unstented tetralogy of Fallot. The routine use of remote ischemic preconditioning cannot be recommended for myocardial protection during pediatric cardiac surgery

Comparative Analysis of Nipple Reconstruction Techniques: Five Flap vs. C-V Flap

Background: Nipple–areola complex reconstruction represents the final phase in the comprehensive post-mastectomy treatment regimen. Despite the diversity of approaches available, there is currently no universally accepted benchmark technique for this critical aspect of breast reconstruction. In this study, we conducted a comparative assessment of two prominent techniques, the five Flap and C-V Flap. Materials and Methods: Between November 2016 and April 2023, we recruited 100 female patients who had undergone unilateral post-oncological mastectomy and divided them into two groups: Group A comprising 50 patients who underwent the 5-Flap technique, whereas Group B comprising the remaining 50 underwent the C-V Flap technique. Over a 6-month observation period, we assessed nipple projection loss and evaluated overall satisfaction through self-reporting by patients and independent assessments by a medical observer. Results: In our study, none of the reconstructed nipples in Group A (5 Flap) experienced either total or partial necrosis, contrasting with Group B (C-V Flap) which encountered a 10% incidence of partial necrosis and 4% incidence of total necrosis. Furthermore, the average nipple projection loss in Group B was substantial, measuring a 30% reduction from the initial projection at the 1-year mark, whereas Group A demonstrated a significantly lower 13% reduction. Notably, despite these variations in outcomes, both groups reported an equal and high level of satisfaction, with patients and external observers providing an average satisfaction score of 8.0 and 9.0, respectively. Conclusion: The five-flap technique represents a safe and effective approach for patients undergoing nipple reconstruction

Graphene-Silicon Device for Visible and Infrared Photodetection

The fabrication of a graphene-silicon (Gr-Si) junction involves the formation of a parallel metal-insulator-semiconductor (MIS) structure, which is often disregarded but plays an important role in the optoelectronic properties of the device. In this work, the transfer of graphene onto a patterned n-type Si substrate, covered by Si3N4, produces a Gr-Si device, in which the parallel MIS consists of a Gr-Si3N4-Si structure surrounding the Gr-Si junction. The Gr-Si device exhibits rectifying behavior with a rectification ratio up to 104. The investigation of its temperature behavior is necessary to accurately estimate the Schottky barrier height (SBH) at zero bias, φb0 = 0.24 eV, the effective Richardson's constant, A* = 7 × 10-10 AK-2 cm-2, and the diode ideality factor n = 2.66 of the Gr-Si junction. The device is operated as a photodetector in both photocurrent and photovoltage mode in the visible and infrared (IR) spectral regions. A responsivity of up to 350 mA/W and an external quantum efficiency (EQE) of up to 75% are achieved in the 500-1200 nm wavelength range. Decreases in responsivity to 0.4 mA/W and EQE to 0.03% are observed above 1200 nm, which is in the IR region beyond the silicon optical band gap, in which photoexcitation is driven by graphene. Finally, a model based on two parallel and opposite diodes, one for the Gr-Si junction and the other for the Gr-Si3N4-Si MIS structure, is proposed to explain the electrical behavior of the Gr-Si device

Multiple Foci of Basal Cell Carcinoma Arising in Rhinophyma: A Case Report and Literature Review

Background: Rhinophyma is a benign condition caused by the excessive growth of sebaceous glands in the nasal tissue, presenting with symptoms such as nasal hypertrophy, erythema, and papules. Cases of basal cell carcinoma in rhinophyma have been reported in literature, but its etiological role remains unclear. It is uncertain whether rhinophyma is predisposed to neoplasm development or if their coexistence is coincidental. Material and Method: We conducted a literature survey to identify such cases reported over the years. Results: We identified 22 studies reporting a total of 47 cases in the literature, all involving male patients. The most common pattern of occurrence was the rapid growth of a nodular formation within the context of rhinophyma. Discussions and Conclusion: The elucidation of the association between basal cell carcinoma and rhinophyma remains challenging. The presence of multiple foci supports the theory that rhinophyma may play a role in their development, but larger studies are needed to establish a causal relationship

Field Emission Characterization of MoS₂ Nanoflowers

Nanostructured materials have wide potential applicability as field emitters due to their high aspect ratio. We hydrothermally synthesized MoS2 nanoflowers on copper foil and characterized their field emission properties, by applying a tip-anode configuration in which a tungsten tip with curvature radius down to 30−100 nm has been used as the anode to measure local properties from small areas down to 1−100 µm2. We demonstrate that MoS2 nanoflowers can be competitive with other well-established field emitters. Indeed, we show that a stable field emission current can be measured with a turn-on field as low as 12 V/μm and a field enhancement factor up to 880 at 0.6 μm cathode−anode separation distance

Field Emission Characterization of MoS2 Nanoflowers

Nanostructured materials have wide potential applicability as field emitters due to their high aspect ratio. We hydrothermally synthesized MoS2 nanoflowers on copper foil and characterized their field emission properties, by applying a tip-anode configuration in which a tungsten tip with curvature radius down to 30-100 nm has been used as the anode to measure local properties from small areas down to 1-100 µm2. We demonstrate that MoS2 nanoflowers can be competitive with other well-established field emitters. Indeed, we show that a stable field emission current can be measured with a turn-on field as low as 12 V/μm and a field enhancement factor up to 880 at 0.6 μm cathode-anode separation distance

Cronache meridionali. A. VI, n.1-12 (1959)

N. 1 (gennaio 1959): L'opposizione e le istanze unitarie del Mezzogiorno, P. 1 ; Alinovi, A., Congresso socialista e rinascita meridionale, P. 7 ; Cinanni, P., Un convegno sulla valorizazione della montagna, P. 17 ; Per la costruzione dello stabilimento siderurgico e l’intervento del l'I.r.i. nel Mezzogiorno, P. 26 ; La risoluzione del Convegno di Napoli, P. 35 ; Viviani, L., Poliomielite e vaccino, P. 35 ; Il « simpatico arcivescovo», P. 38 ; Rimborso spese Risorgimento, P. 39 ; Chiaromonte, G., Il piano regolatore di Napoli, P. 47 ; Amore, S., Un'inchiesta sulla piccola e media industria in Campania, P. 64 ; Giudici, S., Il Banco di Sicilia e l'autonomia, P. 72 ; Valenzi, M., Francesco Gabrieli: Il Risorgimento arabo, P. 77 ; Libro bianco sulle illegalità del governo Fanfani, P. 79 ; Ferdinando Bologna: Francesco Solimena, P.80.N. 2 (febbraio 1959): Il governo dell'on. Segni, P. 81 ; Napolitano, G., I contadini e lo sviluppo dell'agricoltura, P. 83 ; Spallone, G., Problemi dell'emigrazione, P. 99 ; Il movimento di rinascita e la crisi governativa, P. 113 ; Lo sviluppo della cooperazione, P. 114 ; Al di fuori delle leggi, P. 116 ; Dal rapporto dell'O.e.c.e. sull'economia italiana, P. 118 ; Un convegno sull' artigianato, P. 119 ; Gramegna, G., L'agricoltura pugliese e l'imponibile di mano d'opera, P. 128 ; Sotgiu, G., Il piano di rinascita della Sardegna, P. 131 ; Villari, R., Alberto Caracciolo: L'inchiesta agraria Jacini, P. 145 ; Libertà e autonomia per la Sicilia (dal Memorandum dei socialisti di Palermo al senatore Codronchi), P. 152.N. 3 (marzo 1959): Amendola, G., Proposte per un programma dell'opinione democratica italiana, P. 161 ; Failla, V., Petrolio e industrializzazione, P. 168 ; Grifone, P., Crisi agraria e trasformazioni colturali, P. 186 ; Riconsacrazione dell'« iniziativa privata» a Brindisi, P. 199 ; L'abbraccio di Castellammare, P. 200 ; Una proposta dell'ono. Fascetti, P. 201 ; Cimino, M., La Sicilia verso le elezioni, P. 214 ; Sansone, N., Professionisti in un paese pugliese, P. 220 ; Basso, L., Gaetano Salvemini, socialista e meridionalista; Villari, R., Enzo Tagliacozzo: Gaetano Salvemini nel cinquantennio liberale, P. 226 ; Daniele, I., Giuseppe Tomasi Di Lampedusa: Il Gattopardo (I.Daniele), P. 229.N. 4 (aprile 1959): Alicata, M., L'Italia e il patto atlantico, P. 233 ; Chiaromonte, G., L'ottavo esercizio della Cassa per ii Mezzogiorno, P. 236 Valenzi, M., Profughi italiani dalla Tunisia e dall'Egitto, P. 247 ; L'Assemblea generale dell'Isveimer, P. 249 ; Napoli e il centenario del 1860, P. 251 ; De Ciampis, M., Note sul movimento socialista tra gli emigrati italiani in U.S.A. (1890-1921), P. 255 ; Amore, S., Le lotte operaie per lo sviluppo delle Manifatture cotoniere meridionali, P. 274 ; Spallone, G., Bilancio e prospettive dell'industrializzazione, P. 285 ; Esposto, A., Movimento contadino e riforma agraria, P. 294 ; Primo Congresso abruzzese dei lauoratori della terra - Sulmona 18 marzo 1917, P. 305.N. 5 (maggio 1959): Colajanni, N., Le elezioni siciliane, P. 317 ; Li Causi, G., Autonomia regionale e partiti politici in Sicilia, P. 322 ; Miceli, G., Prospettive e condizioni di sviluppo della cooperazione, P. 332 ; Villani, P., Di alcuni presupposti del moderatismo napoletano, P. 363 ; Lauro, Covelli e Segni, P. 356 ; I programmi dell'I.r.i. e dell'E.n.i., P. 357 ; Sede vacante, P. 359 ; Servizio a domicilio, P. 361 ; Una proposta di legge per Napoli, P. 370 ; Pistlllo, M., Panorama preelettorale a Bari, P. 383 ; Sansone, N., Il paradosso di Molfetta, P. 391 ; Napolitano, G., Francesco Compagna: Terroni in città, P. 398 ; Villari, R., Luigi De Rosa: Studi sugli arrendamenti del Regno di Napoli, P. 400 ; Ricci, P., Riccardo Raimondi: Degas e la sua famiglia in Napoli, P. 402.N. 6 (giugno 1959): Pajetta, G., Il valore nazionale del voto siciliano, P. L'ingegner La Cavera e la Confindustria, P. 421 ; Caprara, M., Il progetto di legge per Napoli, P. 422 ; De Jaco, A., La stampa italiana e il processo a Pupetta Maresca, P. 424 ; Chiaromonte, G., L'assistenza pubblica a Napoli, P. 449 ; Napolitano, G., Domenico La Cavera:Petrolio e azione di governo ai fini dell'industrializzazione in Sicilia; ID.: Un decennio di travaglio per l'industrializzazione della economia siciliana, P. 457 ; Villari, R., Karl Kautsky: La questione agraria, P. 400 ; Daniele., I., Domenico Rea: Una vampata di rossore, P. 463 ; Causa, R., La mostra celebrativa di Michele Cammarano, P. 464 ; Domanico, G., Discussioni sulla questione agraria e proposte per i contadini, P. 467.N. 7-8 (luglio-agosto 1959): Alinovi, A., Spinta meridionalista, P. 473 ; Natta, A., Il problema della scuola, P. 477 ; D'Antonio, M., e I. Palermo, Il Banco di Napoli e la stampa napoletana , P. 486 ; Villari, R., La polemica antiriiormista di Arturo Labriola, P. 497 ; L'industria di Stato e il Mezzogiorno, P. 506 ; Cutolo e De Micheli, P. 507 ; Formiggini, G., La legge siciliana di riforma amministrativa, P. 512 ; Per una legge organica a favore delle piccole e medie imprese industriali, P. 526 ; Modifiche e integrazioni della legge recante provvedimenti per il Mezzogiorno, P. 538 ; Pirastu, L., La lotta del popolo sardo per il piano di rinascita, P. 545 ; Petrone, I., L'industrializzazione della Lucania, P. 549 ; Berlinguer, G., e S. Delogu, La medicina è malata, P. 555 ; Daniele, I., Ottiero Ottieri: Donnarumma all'assalto, P. 557 ; Rossi, R., Federico De Roberto: I Vicerè, P. 559 ; Labriola, A., La questione meridionale e le riforme del periodo Giolittiano, P. 561.N. 9 (settembre 1959): Calamandrei, F., Il Mezzogiorno e la svolta internazionale, P. 569 ; Chiaromonte, G., e L. Cosenza, Il piano regionale campano, P. 576 ; Gomez, M., I prezzi delle patate, P. 593 ; Caprara, M., Tre proposte di legge per Napoli, P. 604 ; Una inchiesta sulle attrezzature civili del Mezzogiorno, P. 611 ; Iocco, E. Per lo sviluppo della piccola e media industria, P. 622 ; Sommario della legislazione a favore delle industrie, P. 626 ; Cimino, M., I contagiosi casi di Sicilia, P. 635 ; Rizzo, G.,Lo sciopero dei conservieri a Mugnano, P. 641 ; Villari, R., Georges Lefebvre: Les paysans du Nord pendant la Révolution française, P. 645 ; Valenza, P., Michele Lacalamita: La civiltà contadina, P. 648, Daniele, I., Aldo De Jaco: Una settimana eccezionale, P. 650.N. 10 (ottobre 1959): Il Congresso della Democrazia cristiana, P. 653 ; Chiaromonte, G., La pianificazione regionale, P. 656 ; Natta, A., Il progetto Medici per la scuola, P. 662 ; Caprara, M., La tortuosa vicenda del rinino delle elezioni, P. 670 ; Il programma del P.d.i., 677 Corrao, L., Cosa vuole la Sicilia, P. 684 ; Proposte per lo sviluppo economico della Sicilia, P. 700 ; Il metano di Ferrandina, P. 706 ; Maglietta, C., Per lo sviluppo della piccola e media industria, P. 708 ; Sul progetto di legge per fusioni e trasformazioni di società, P. 712 ; D'Antonio, M., e I. Palermo, Confusione e trasformismo nella D.c. a Napoli, P. 719.N. 11 (novembre 1959): Chiaromonte, G., l congressi democristiani nel Mezzogiorno, P. 733 ; Napolitano, G., Dci piani regionali a una nuova politica economica, P. 746 ; Fontani, A., Emigrazione e movimento di popolazione, P. 750 ; Sansone, N., Il processo di Marigliano, P. 767 ; La Cavera, D., e R. Posca (interventi nel dibattito di), Per lo sviluppo della piccola e media industria, P. 771 ; Caprara, M., Il Premio Nobel a Salvatore Quasimodo, P. 778 ; Ziccardi, A., L'Ente di irrigazione appulo-lucano, P.787 ; Pellegrino, G., La pesca nel Canale di Sicilia, P. 793 ; Villari, R., Storia dell'economia italiana, a cura di C. M. Cipolla, P. 799 ; Boeri, E., Theodor Heuss: L'«Acquario» di Napoli e il suo fondatore Antonio Dohrn, P. 802 ; Gaetano Salvemini: Suffragio universale e clericalismo, P. 805.N. 12 (dicembre 1959): Longo, L., Monopoli e industrializzazione in Sicilia, P. 809 ; Valenzi, P., e L. Silipo, L'alluvione in Lucania e Calabria, P. 823 ; Lapiccirella, R., L'incredibile vicenda dell'acquedotto campano, P. 834 ; Napolitano, G., Piani regionali ed attuazione delle Regioni, P. 839 ; Valenzi, M., La terza Conferenza di Belgrado. Anticolonialismo e distensione, P. 847 ; Chiarnomonte, G., Ancora sullalegge speciale per Napoli, P. 849 ; Amore, S., Il M.e.c. e la provincia di Napoli, P. 858 ; Fermariello, C. ( intervento nel dibattito di ) Per lo sviluppo della piccola e media industria, P. 860 ; Progetto di legge per la « Modifica del sistema contributivo delle assicurazioni sociali a favore delle piccole e medie aziende industriali», P. 865 ; Pelella, E., L'industria calzaturiera a Napoli, P. 868 ; Chiaromonte, G., Emilio Luongo - Antonio Oliva: Napoli come è, P. 873 ; Villari, R., Critica sociale, a cura di M. Spinella, A. Caracciolo, H. Amaduzzi, G. Petronio, P. 876