EKG:n pitkäaikaisrekisteröinti

Vertaisarvioitu. Näin tutkin.EKG:n pitkäaikaisrekisteröinnillä tarkoitetaan menetelmiä, joiden avulla sydämen sähköistä toimintaa seurataan mukana kuljetettavan rekisteröintilaitteen avulla. Alkuperäisen, Sir Norman Holterin kehittämän, EKG:tä jatkuvasti rekisteröivän laitteiston rinnalle on sittemmin kehitetty menetelmiä, joissa talteen kerätään ainoastaan tietyt kriteerit täyttävät löydökset sekä löydökset tutkittavan potilaan oireiden ajalta. Tavallisimmat EKG:n pitkäaikaisrekisteröinnin aiheet ovat olleet rytmihäiriötuntemusten selvittely ja etiologialtaan epäselvä synkopee. Rekisteröintilaitteiden sekä muun kardiologisen diagnostiikan ja hoidon kehitys on merkittävästi laajentanut ja muovannut tutkimusaiheita

Seventh time lucky-A case report of multiple radiofrequency ablations for right ventricular outflow tract tachycardia

Right ventricular outflow tachycardia initially refractory to radiofrequency ablation may be successfully treated after radiofrequency ablation at multiple sites. Repeated radiofrequency ablations as well as cooperation across borders with referral to an international center of excellence may be required in complicated casesPeer reviewe

Self-organizing map modelling and prospectivity mapping of surface geochemical data in Au and multi-metal mineral exploration: example from northern Finland

Abstract Regional till and weathered bedrock geochemical datasets provide a basis for data analysis and modelling in glaciated terrains. These large-scale surface geochemical datasets have great potential in mineral exploration, especially when machine learning and clustering methods are used to reduce the dimensionality of multivariate datasets. Here, self-organizing maps (SOMs) followed by k-means clustering were used to create SOMs of the target areas for initial modelling and prospectivity mapping of gold (Au) prospecting in central Lapland, northern Finland. Because the till and weathered bedrock datasets are legacy data, an effort was made to level the data between the map sheets. The targeting till geochemical dataset did not contain the typical indicator elements for Au. Instead, elements associated with the Au deposits, within the study area, were used. Indicator associations in this study were Ni–Co with possible Cu. Resulting elemental clusters from the SOMs were assigned as interesting clusters according to their distribution of elements. For the till, two potential clusters were identified: Ni–Co–Cr and Cu–V–Co. For the weathered bedrock, three clusters were specified: Ni–Co–Cr, V–Cu and Cu–Co. This study shows the potential of using legacy datasets for early targeting stages of mineral exploration, potentially reducing the footprint of mineral exploration.Abstract Regional till and weathered bedrock geochemical datasets provide a basis for data analysis and modelling in glaciated terrains. These large-scale surface geochemical datasets have great potential in mineral exploration, especially when machine learning and clustering methods are used to reduce the dimensionality of multivariate datasets. Here, self-organizing maps (SOMs) followed by k-means clustering were used to create SOMs of the target areas for initial modelling and prospectivity mapping of gold (Au) prospecting in central Lapland, northern Finland. Because the till and weathered bedrock datasets are legacy data, an effort was made to level the data between the map sheets. The targeting till geochemical dataset did not contain the typical indicator elements for Au. Instead, elements associated with the Au deposits, within the study area, were used. Indicator associations in this study were Ni–Co with possible Cu. Resulting elemental clusters from the SOMs were assigned as interesting clusters according to their distribution of elements. For the till, two potential clusters were identified: Ni–Co–Cr and Cu–V–Co. For the weathered bedrock, three clusters were specified: Ni–Co–Cr, V–Cu and Cu–Co. This study shows the potential of using legacy datasets for early targeting stages of mineral exploration, potentially reducing the footprint of mineral exploration

Oraalinen antikoagulaatiohoito sydänsairauksissa

Sydänpotilailla antikoagulaatiolääkityksen tärkeimmät käyttöaiheet ovat eteisvärinä, mekaaninen tekoläppä ja vaikea hiippaläpän ahtauma. Muissa sydänsairauksissa antikoagulaatiohoitoa ei yleensä käytetä, ellei liitännäissairaus edellytä sitä. Vakaassa sepelvaltimotaudissa riittää yleensä suora antikoagulantti tai varfariini yksinään. Asetyylisalisyylihapon tai ADP-reseptorin salpaajan samanaikainen käyttö lisää vuotovaaraa. Tavanomaisissa sydäntoimenpiteissä hoitoa ei yleensä tauoteta.Peer reviewe

Eteisvärinän lääkehoito

Teema : eteisvärinä. English summaryPeer reviewe

Senior citizens evaluating welfare technology: User experiences in SENER-project

´In an aging society, it is important to work for finding ways to integrate seniors in the society and to pursue seniors’ wellbeing and independent living. The aim of this research is to explore the potential of information and communication technology (ICT) in enhancing active aging. More precisely, the research examines user experiences of 24 senior citizens in piloting health technology, the wellbeing box products, in the SENER-project.The data were collected in interviews including semi-structured questions concerning senior citizens’ experiences. In addition to qualitative data, information about usage times of tested devices or programs was analyzed to construct user type categories.Three main type categories emerged: drop-outs, passive users, and active users. Drop-outs were too fragile to see more benefit than nuisance in the devices. In cases of passive users, families benefited more of the devices than the seniors themselves. Active users used the devices and programs themselves in various ways, for example monitored their health.Senior citizens are heterogeneous in their use of ICT. Products of the wellbeing box were motivating in the sense of active aging policy if there existed an interest in health promotion. Seniors must not feel too fragile, and they have to see more benefits than nuisance in the use of ICT if they want to start to use it. Devices must not have technical problems, and enough guidance that matches the skills of the users must be offered. Senior citizens do not want technology to replace human help, but health information gathered by monitoring devices could be transmitted to home help personnel

Challenges and Governance Solutions for Data Science Services based on Open Data and APIs

Peer reviewe