Considerations and strategies for incorporating lived experience in mental health research

Introduction: Incorporating lived experience in mental health research deserves special focus due to the unique stigma faced by those with lived experience and the unique gap between the experience and expression of mental health struggle.https://knowledgeconnection.mainehealth.org/lambrew-retreat-2023/1029/thumbnail.jp

Body Pedagogics: Embodiment, Cognition and Cultural Transmission

This paper contributes to the growing sociological concern with body pedagogics; an embodied approach to the transmission and acquisition of occupational, sporting, religious and other culturally structured practices. Focused upon the relationship between those social, technological and material means through which institutionalized cultures are transmitted, the experiences of those involved in this learning, and the embodied outcomes of this process, existing research highlights the significance of body work, practical techniques, and the senses to these pedagogic processes. What has yet to be explicated adequately, however, is the embodied importance of cognition to this incorporation of culture. In what follows, I address this lacuna by building on John Dewey’s writings in proposing an approach to body pedagogics sympathetic to the prioritization of physical experience but that recognizes the distinctive properties and capacities of thought and reflexivity in these processes

What contribution can insights from the complexity sciences make to the theory and practice of development management?

‘The definitive version is available at www3.interscience.wiley.com '. Copyright Wiley [Full text of this article is not available in the UHRA]This paper offers a critique of existing ways of understanding management practice in International Non-Government Organisations (INGOs) and compares and contrasts these with insights drawn from the complexity sciences. The authors put forward a more radical interpretation of complexity theory as it might be taken up in organisations rather than suggesting that it can be accommodated with existing theories based in systems thinking. They suggest that understanding the process of organising as contingent, paradoxical and experiential could profoundly refocus the attention of managers and practitioners alike and lead to an intensifying of practice as more consciously political. In being more open to others, including their partners and beneficiaries, staff in INGOs may be more ready to change themselves and their ideas. At the same time, the authors point out the existing dynamics of current practice and the way it perpetuates itself, no matter how problematic. Copyright#2008 JohnWiley & Sons, Ltd.Peer reviewe

Mazlum milletlerin kurtuluş savaşları karşısında S.S.C.B ve Sultan Galiev : Türkiye sollarındaki stratejik bölünme ve Galievizm

Donated by Klaus Kreise

Identification of specific reachable molecular targets in human breast cancer using a versatile ex vivo proteomic method

Targeting of tumoral tissues is one of the most promising approaches to improve both the efficacy and safety of anticancer treatments. The identification of valid targets, including proteins specifically and abundantly expressed in cancer lesions, is of utmost importance. Despite state-of-the-art technologies, the discovery of cancer-associated target proteins still faces the limitation, in human tissues, of antigen accessibility to suitable high-affinity ligands such as human mAb bound to bioactive molecules. Terminal perfusion of tumor-bearing mice or ex vivo perfusion of human cancer-bearing organs with a reactive biotin ester solution has successfully led to the identification of novel accessible biomarkers. This methodology is however restricted to perfusable organs, and excludes most of the tissues of interest to targeted therapies, e.g. primary breast cancer and metastases. Herein, we report on the development of a new chemical proteomic method that bypasses the perfusion step and thus offers the potential to identify accessible molecular targets in virtually all types of animal and human tissues. We have validated our new procedure by identifying biomarkers selectively expressed in human breast carcinoma. Overall, this powerful technology may lay the ground not only for custom-made therapies in cancer, but also for the development of therapies that need to be selectively delivered in a specific tissue