475 research outputs found

    Interpolation of SUSY quantum mechanics

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    Interpolation of two adjacent Hamiltonians in SUSY quantum mechanics Hs=(1−s)A†A+sAA†H_s=(1-s)A^{\dagger}A + sAA^{\dagger}, 0≤s≤10\le s\le 1 is discussed together with related operators. For a wide variety of shape-invariant degree one quantum mechanics and their `discrete' counterparts, the interpolation Hamiltonian is also shape-invariant, that is it takes the same form as the original Hamiltonian with shifted coupling constant(s).Comment: 18 page

    Modeling and Validation of 2-DOF Rail Vehicle Model Based on Electro–Mechanical Analogy Theory Using Theoretical and Experimental Methods

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    This paper presents theoretical and experimental results on modeling and simulation of two degrees of freedom rail vehicle by using electro-mechanical similarity theory. In this study, the equations of motion were derived using Newton’s second law of motion and then mechanical and equivalent electrical circuits were obtained with the help of a free body diagram. A schema in Simulink allowing analyzing of the behavior of the primary and secondary suspension was created. In order to verify the electrical model, transfer function and schema were developed in Simulink. The simulation results were compared with the experimental data and the comparison showed that the results of the mechanical experiments were close to the simulation results, but the electrical results showed better periodic behavior

    Stylistic document retrieval for Turkish

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    In information retrieval (IR) systems, there are a query and a collection of documents compared with this query and ranked according to a particular similarity measure. Since texts with the same content can be written by different authors, the writing styles of the documents change as well accordingly. This observation brings the idea of investigating text by means of style. In this paper, we analyze text documents in terms of stylistic features of the written text and measure effectiveness of these features in an IR system. Our main focus is on Turkish text documents. Although there are many studies about broadening IR systems with style based enhancement, there is no similar application for Turkish which performs retrieval depending purely on style. © 2009 IEEE

    Analytical Benchmark Problems for Multifidelity Optimization Methods

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    The paper presents a collection of analytical benchmark problems specifically selected to provide a set of stress tests for the assessment of multifidelity optimization methods. In addition, the paper discusses a comprehensive ensemble of metrics and criteria recommended for the rigorous and meaningful assessment of the performance of multifidelity strategies and algorithms

    A supportive text message intervention for individuals living with endometriosis (EndoSMS) : randomized controlled pilot and feasibility trial

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    Introduction: As a high symptom burden chronic condition, endometriosis is associated with diminished quality of life (QoL) and psychological distress. The EndoSMS text message intervention was developed to inform and support individuals living with endometriosis. The primary aim of this study is to assess the acceptability, feasibility and preliminary efficacy of EndoSMS, to improve endometriosis-specific QoL and reduce psychological distress in a randomised controlled trial, compared with care as usual. We will additionally assess the impact of EndoSMS on self-efficacy for managing endometriosis. Methodology: A two-arm parallel pilot randomised controlled trial with waitlist control was conducted. Baseline assessments included QoL, psychological distress, self-efficacy, demographic and medical variables. Following baseline survey completion, participants were randomised to either the Intervention (EndoSMS: 3-months of text messaging) or Control condition. At 3-month follow-up, all participants completed an online survey reassessing outcomes, and Intervention participants provided quantitative and qualitative user feedback on EndoSMS. Results: Data collection commenced on 18 November 2021 and was completed on 30 March 2022. Descriptive statistics will be used to analyse feasibility and acceptability of the intervention. Preliminary efficacy analyses will be conducted using linear mixed models for QoL, psychological distress and self-efficacy outcomes. Subgroup analyses will also be conducted for typically underserved populations (e.g., rural/regional). Conclusion: This pilot will provide acceptability, feasibility and preliminary efficacy evidence for the impact of a supportive text messaging program for endometriosis. It will contribute to understanding how to optimally support individuals in living with and managing their endometriosis. Trial Registration: Australian New Zealand Clinical Trials Registry

    Pharmacological Properties of Edible Asparagus acutifolius and Asparagus officinalis Collected from North Iraq and Turkey (Hatay)

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    In this study, antioxidant, oxidant, antimicrobial, and antiproliferative activities of Asparagus acutifolius L. and Asparagus officinalis L., known for their nutritional properties, were determined. In this context, methanol (MeOH) and dichloromethane (DCM) extracts of plants were obtained. Total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were determined using Rel Assay kits. Antimicrobial activities of plant extracts were determined against the test microorganisms using the agar dilution method. Antiproliferative activity was tested on the lung cancer cell line A549. As a result of the studies, it has been determined that the plant species have high antioxidant potential. In addition, it was observed that the antifungal potentials of plant extracts are high. Antiproliferative activity was determined to be at high level in both plant species. As a result, it has been determined that A. acutifolius and A. officinalis have medical potential and can be used as natural agents in pharmacological designs

    A Novel GUI Design for Comparison of ROS-Based Mobile Robot Local Planners

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    The studies such as navigating the AMR between stations, docking to the station, and assigning autonomous tasks to other stations are costly in terms of time and energy consumption. This situation creates the need for an interface where the entire work area can be observed and AMRs can be controlled from a single center in the installation of the system in the field. In this study, an interface that can be used in AMR control and monitoring was designed. With this interface; It is thought to prevent costly situations such as determining the stations, calculating the time spent in the transportation of products between stations, determining the movement route. The interface developed in this context was used in an application where ROS-based path planning algorithms were compared. A total of six different stations was identified. With three different local planners: DWA, TEB and Trajectory planner, AMR was given the task of acting autonomously to each station. Thanks to the developed interface, the distance and time required to reach each station were calculated by performing autonomous movement to the desired points. In this way, a comparison of ROS-based path planning algorithms was made. It was calculated that the DWA was 10.55% more successful than the TEB and 2.33% more successful than the Trajectory in terms of distance covered. Additionally, when examined in terms of arrival time, it was calculated that the DWA was 24.64% more successful than the TEB and 2.39% more successful than the Trajectory

    Co-design and development of EndoSMS, a supportive text message intervention for individuals living with endometriosis : mixed methods study

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    Background: Endometriosis, which affects 1 in 10 people assigned female at birth, is a chronic systemic inflammatory disease with a high symptom burden and adverse socioemotional impacts. There is a need for an accessible, cost-effective, and low-burden intervention to support individuals in managing their endometriosis condition. Objective: This study aimed to co-design and evaluate the acceptability, readability, and quality of a bank of supportive SMS text messages (EndoSMS) for individuals with endometriosis. Methods: In phase 1 of this mixed method design, 17 consumer representatives (individuals with endometriosis) participated across three 3-hour web-based (Zoom, Zoom Video Communications, Inc) focus groups. The transcripts were encoded and analyzed thematically. In phase 2, consumer representatives (n=14) and health care professionals (n=9) quantitatively rated the acceptability, readability, and appropriateness of the developed text messages in a web-based survey. All the participants initially completed a background survey assessing sociodemographic and medical factors. Results: Consumer representatives demonstrated diverse sociodemographic characteristics (Mage=33.29), varying in location (metropolitan vs rural or regional), employment, and relationship and educational statuses. Participants reached a consensus regarding the delivery of 4 SMS text messages per week, delivered randomly throughout the week and in one direction (ie, no reply), with customization for the time of day and use of personal names. Seven main areas of unmet need for which participants required assistance were identified, which subsequently became the topic areas for the developed SMS text messages: emotional health, social support, looking after and caring for your body, patient empowerment, interpersonal issues, general endometriosis information, and physical health. Through a web-based survey, 371 co-designed SMS text messages were highly rated by consumers and health care professionals as clear, useful, and appropriate for individuals with endometriosis. Readability indices (Flesch-Kincaid scale) indicated that the SMS text messages were accessible to individuals with a minimum of 7th grade high school education. Conclusions: On the basis of the needs and preferences of a diverse consumer representative group, we co-designed EndoSMS, a supportive SMS text message program for individuals with endometriosis. The initial evaluation of the SMS text messages by consumer representatives and health professionals suggested the high acceptability and suitability of the developed SMS text messages. Future studies should further evaluate the acceptability and effectiveness of EndoSMS in a broader population of individuals with endometriosis

    Biallelic variants in ADAMTS15 cause a novel form of distal arthrogryposis

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    Purpose We aimed to identify the underlying genetic cause for a novel form of distal arthrogryposis. Methods Rare variant family-based genomics, exome sequencing, and disease-specific panel sequencing were used to detect ADAMTS15 variants in affected individuals. Adamts15 expression was analyzed at the single-cell level during murine embryogenesis. Expression patterns were characterized using in situ hybridization and RNAscope. Results We identified homozygous rare variant alleles of ADAMTS15 in 5 affected individuals from 4 unrelated consanguineous families presenting with congenital flexion contractures of the interphalangeal joints and hypoplastic or absent palmar creases. Radiographic investigations showed physiological interphalangeal joint morphology. Additional features included knee, Achilles tendon, and toe contractures, spinal stiffness, scoliosis, and orthodontic abnormalities. Analysis of mouse whole-embryo single-cell sequencing data revealed a tightly regulated Adamts15 expression in the limb mesenchyme between embryonic stages E11.5 and E15.0. A perimuscular and peritendinous expression was evident in in situ hybridization in the developing mouse limb. In accordance, RNAscope analysis detected a significant coexpression with Osr1, but not with markers for skeletal muscle or joint formation. Conclusion In aggregate, our findings provide evidence that rare biallelic recessive trait variants in ADAMTS15 cause a novel autosomal recessive connective tissue disorder, resulting in a distal arthrogryposis syndrome
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