Design of innovative protective insoles: a hybrid component for safety footwear

The use of Personal Protective Equipment (PPE) has become a necessity in view of the number of accidents at work that occurred in the past years. The European Community (EU) and the member states are creating strategies aiming the increase of the use of PPE’s and consequently the decrease of the number of the accidents at work, decreasing also the number of injuries caused by them and their severity. In this paper, a brief review of safety footwear and its components will be presented focusing on penetration resistant inserts. Additionally, we present a project in development at University of Minho that aims to improve the existent shoes. This project aims the development of a new and innovative methodology for design a surface of a penetration resitant insert based in the anthropometry and biomechanical analysis of the foot. This methodology allows the design of a penetration resistant insert more comfortable and appellative than the already existent.The financial funding from QREN, POFC, Vale Inovação Project nº2012/24148 is also gratefully acknowledged

Florística e Fitossociologia de um campo natural no município de Santo Antonio da Patrulha, Rio Grande do Sul, Brasil

A floristic and phytosociological survey of a campos grassland was conducted in a private area of approximately 20 ha. The grassland-covered areas are discontinuous, together covering approximately 10 ha. The method applied in the floristic survey was the “Caminhamento”. The obtained floristic list contains 123 botanical species, distributed in 83 genera and 31 families. The phytosociological survey was carried out in 20 0.25 m2 (0.5 m x 0.5 m) plots, and 66 species where sampled. For estimation of the species’ covering values, we used the surface method with a modification of the Braun-Blanquet cover scale. The values recovered for the Shannon-Wiener Diversity Index and the Pielou Equitability Index were 3.63 nats and 0.87, respectively.Resumo: (Florística e fitossociologia de um campo natural no município de Santo Antonio da Patrulha, Rio Grande do Sul, Brasil). Foi realizado um levantamento florístico e fitossociológico das fisionomias campestres presentes em uma área particular de aproximadamente 20 ha. As áreas campestres são descontínuas, totalizando uma cobertura de ca. 10 ha. A metodologia utilizada no levantamento florístico foi o Caminhamento. A lista florística obtida contém 123 espécies botânicas, distribuídas em 83 gêneros e 31 famílias. O levantamento fitossociológico foi realizado em 20 unidades amostrais de 0,25 m2 (0,5 m x 0,5 m), e 66 espécies foram amostradas. Para estimar a cobertura das espécies utilizou-se o método de superfície com uma modificação da escala de cobertura de Braun-Blanquet. Os valores encontrados para o Índice de Diversidade de Shannon-Wiener e para o Índice de Equidade de Pielou foram, respectivamente, 3,63 nats e 0,87

Floristic and vegetation structure of a granitic grassland in Southern Brazil

A floristic and structural survey of a natural grassland community was conducted on Morro do Osso, a granitic hill in Porto Alegre, RS, Brazil. Structural data were surveyed in 39 one square meter plots placed over two major grassland areas. An accidental fire has occurred in one of the areas approximately one year prior to our survey, leading to further analysis of parameters differences between sites. The floristic list contains 282 species, whereas the structural survey has found 161 species. Families with highest accumulated importance values were Poaceae, Asteraceae and Fabaceae. The diversity and evenness indexes were 4.51 nats ind-1 and 0.86, respectively. Cluster analysis denoted two groups coinciding with the areas distinguished by the fire disturbance. A similarity analysis between our data and two other data sets from nearby granitic hills resulted in 28% to 35% similarity, with equivalent species-family distribution and many common dominant species, corroborating the concept of a continuous flora along the South Brazilian granitic hills.Um levantamento florístico e estrutural de uma comunidade de campo natural foi conduzido no Morro do Osso, um morro granítico em Porto Alegre, RS, Brasil. Os dados estruturais foram obtidos em 39 quadros de 1 m², dispostos em duas grandes áreas de campo. Uma queimada acidental ocorreu em uma das áreas, aproximadamente um ano antes do levantamento, propiciando a análise de diferenças entre os parâmetros dos dois sítios de amostragem. A lista florística contém 282 espécies e, no levantamento estrutural, foram encontradas 161 espécies. As famílias com maior valor de importância acumulado foram Poaceae, Asteraceae e Fabaceae. Os índices de diversidade e a equabilidade foram 4,51 nats ind-1 e 0,86, respectivamente. A análise de agrupamento identificou dois grupos nítidos, que coincidem com os locais atingidos ou não pelo fogo. Uma análise de similaridade entre os dados obtidos e dois outros conjuntos de dados de morros graníticos vizinhos resultou em 28% a 35% de similaridade, com uma equivalente distribuição de espécies por família e muitas espécies dominantes comuns, corroborando a noção de continuidade da flora ao longo dos morros graníticos no sul do Brasil

A protective safety footwear device simulation and design: an innovative and healthy hybrid component

The use of Personal Protective Equipment (PPE) has become a necessity in view of the number of accidents at work that occurred in the past years. The European Community (EU) and the member states are creating strategies aiming the increase of the use of PPE's and consequently the decrease of the number of the accidents at work, decreasing also the number of injuries caused by them and their severity. In this paper, a brief review of safety footwear and its components will be presented focusing on penetration resistant inserts. Additionally, we present a project in development at University of Minho that aims to improve the existent shoes. This project proposes a brand new penetration resistant inserts through a combination of innovative materials.info:eu-repo/semantics/publishedVersio

A família Cyperaceae no Parque Estadual de Itapuã, Viamão, Rio Grande do Sul, Brasil

Cyperaceae is a cosmopolitan monocot family that is composed by more than 5,000 species distributed in 104 genera. In Brazil occur about 700 species distributed in approximately 44 genera. The present paper consists in the floristic survey of Cyperaceae species occurring in the Parque Estadual de Itapuã, Viamão, Rio Grande do Sul, Brazil. The study area presents forest, grassland and sandbank environments. Those physiognomies originally formed mosaics all over Patos Lagoon and Guaíba Lake regions. The survey was carried out through field collections and herbaria revision. The Cyperaceae family is represented by 60 species and one variety distributed in 14 genera. Cyperus (14 spp. and one variety), Rhynchospora (10 spp.) and Eleocharis (9 spp.) presented greater species number. Illustrated keys for the identification of genera and species are presented, moreover, complementary information concerning habitat, status and comments are also presented for each species.Cyperaceae é uma família cosmopolita de monocotiledôneas composta por mais de 5.000 espécies, distribuídas em 104 gêneros. No Brasil ocorrem cerca de 700 espécies, distribuídas em aproximadamente 44 gêneros. O presente trabalho consiste no levantamento florístico das espécies de Cyperaceae presentes no Parque Estadual de Itapuã, Viamão, Rio Grande do Sul. A área de estudo apresenta formações florestais, campestres e de restinga, sendo que essas fisionomias originalmente formavam mosaicos em toda a região das orlas da Laguna dos Patos e do Lago Guaíba. O levantamento foi realizado com base em coletas a campo e revisão de herbários. A família Cyperaceae está representada por 60 espécies e uma variedade distribuídas em 14 gêneros, sendo que os gêneros Cyperus (14 spp. e uma variedade), Rhynchospora (10 spp.) e Eleocharis (9 spp.) apresentaram o maior número de espécies. Apresentam-se chaves dicotômicas ilustradas para a identificação de gêneros e espécies, além de informações acerca do hábitat, status e observações complementares

1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as potential inhibitors of VEGFR-2: synthesis and molecular modelling studies

Angiogenesis is a requirement for tumor growth and metastasis and occurs through several signalling pathways. One key pathway that initiates proliferation and migration of endothelial cells is signalling through the vascular endothelial growth factor receptor-2 (VEGFR-2).1 Therefore, small molecules that block this signalling pathway through inhibition of the VEGFR tyrosine kinase activity could potentially inhibit angiogenesis and tumour growth. Recently works describing thienopyrimidines2 and thienopyridine ureas3 as inhibitors of VEGFR-2 have appeared in the literature. Here we present the synthesis of new 1,3-diarylureas 2 starting by regioselective nucleophilic substitution of the 4-chlorothieno[3,2-d]pyrimidine with 4-aminophenol to obtain 4-(thieno[3,2-d]pyridin-4-yloxy)aniline 1 which reacts with different arylisocyanate

Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines

Thienopyridine skeleton has been reported as havi ng inte resting biological activity, namely antitumorlll and antiangiogenic121 activities. Herein, we describe the synth esis of thienopyridine arylethers la-f in moderate to good yields by a copper-cata lyzed C- 0 coupling, using N,N-dimethylglycine as a ligand, of the 7-bromothieno[3,2-b]pyridine, also prepared with substituted phenols (see scheme)

1-aryl-3-(4-(7-methylthieno[3,2-d]pyrimidin-4-yloxy)phenyl)ureas: synthesis and molecular modelling studies using VEGFR-2

The development of anticancer drugs inhibiting angiogenesis has been an area of extensive research in the past decade. Angiogenesis is a requirement for tumor growth and metastasis and occurs through several signalling pathways. One key pathway that initiates proliferation and migration of endothelial cells is signalling through the vascular endothelial growth factor receptor-2 (VEGFR-2).1 Therefore, small molecules that block this signalling pathway through inhibition of VEGFR-2 tyrosine kinase activity could potentially inhibit angiogenesis and tumor growth. Recently works describing thienopyrimidine2 and thienopyrimidine 1,3-diarylureas3 as VEGFR-2 inhibitors have emerged in the literature. Here we present the synthesis of new 1-aryl-3-(4-(7-methylthieno[3,2-d]pyrimidin-4-yloxy)phenyl)ureas 2 in high yields by reaction of 4-[(7-methylthieno[3,2-d]pyridin-4-yl)oxy]aniline 1 with arylisocyanates. The former was prepared by regioselective nucleophilic substitution of 4-chloro-7-methylthieno[3,2-d]pyrimidine with 4-aminopheno

Floral features, pollination biology and breeding system of Chloraea membranacea Lindl. (Orchidaceae: Chloraeinae)

Background and Aims: The pollination biology of very few Chloraeinae orchids has been studied to date, and most of these studies have focused on breeding systems and fruiting success. Chloraea membranacea Lindl. is one of the few non-Andean species in this group, and the aim of the present contribution is to elucidate the pollination biology, functional floral morphology and breeding system in native populations of this species from Argentina (Buenos Aires) and Brazil (Rio Grande do Sul State). Methods:Floral features were examined using light microscopy, and scanning and transmission electron microscopy. The breeding system was studied by means of controlled pollinations applied to plants, either bagged in the field or cultivated in a glasshouse. Pollination observations were made on natural populations, and pollinator behaviour was recorded by means of photography and video.Key ResultsBoth Argentinean and Brazilian plants were very consistent regarding all studied features. Flowers are nectarless but scented and anatomical analysis indicates that the dark, clavate projections on the adaxial labellar surface are osmophores (scent-producing glands). The plants are self-compatible but pollinator-dependent. The fruit-set obtained through cross-pollination and manual self-pollination was almost identical. The main pollinators are male and female Halictidae bees that withdraw the pollinarium when leaving the flower. Remarkably, the bees tend to visit more than one flower per inflorescence, thus promoting self-pollination (geitonogamy). Fruiting success in Brazilian plants reached 60·78 in 2010 and 46 in 2011. Some pollinarium-laden female bees were observed transferring pollen from the carried pollinarium to their hind legs. The use of pollen by pollinators is a rare record for Orchidaceae in general.ConclusionsChloraea membrancea is pollinated by deceit. Together, self-compatibility, pollinarium texture, pollinator abundance and behaviour may account for the observed high fruiting success. It is suggested that a reappraisal and re-analysis of important flower features in Chloraeinae orchids is necessary.Fil: Sanguinetti, Agustin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental; ArgentinaFil: Buzatto, Cristiano Roberto. Universidade Federal do Rio Grande do Sul; BrasilFil: Pedron, Marcelo. Universidade Federal do Rio Grande do Sul; BrasilFil: Davies, Kevin L.. Cardiff University; Reino UnidoFil: Ferreira, Pedro Maria De Abreu. Universidade Federal do Rio Grande do Sul; BrasilFil: Maldonado, Sara Beatriz. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria; ArgentinaFil: Singer, Rodrigo Bustos. Universidade Federal do Rio Grande do Sul; Brasi