Infrared Imaging of Capella with the IOTA Closure Phase Interferometer

We present infrared aperture synthesis maps produced with the upgraded IOTA interferometer. Michelson interferograms on the close binary system Capella (Alpha Aur) were obtained in the H-band between 2002 November 12 and 16 using the IONIC3 beam combiner. With baselines of 15m < B < 38m, we were able to determine the relative position of the binary components with milliarcsecond (mas) precision and to track their movement along the approx. 14 degree arc covered by our observation run. We briefly describe the algorithms used for visibility and closure phase estimation. Three different Hybrid Mapping and Bispectrum Fitting techniques were implemented within one software framework and used to reconstruct the source brightness distribution. By dividing our data into subsets, the system could be mapped at three epochs, revealing the motion of the stars. The precise position of the binary components was also determined with model fits, which in addition revealed I_Aa/I_Ab=1.49 +/- 0.10 and apparent stellar uniform-disk (UD) diameters of Theta_Aa=8.9 +/- 0.6 mas and Theta_Ab=5.8 +/- 0.8 mas. To improve the u, v-plane coverage, we compensated this orbital motion by applying a rotation-compensating coordinate transformation. The resulting model-independent map with a beam size of 5.4 x 2.6 mas allows the resolution of the stellar surfaces of the Capella giants themselves.Comment: Accepted by the Astronomical Journal (2005-03-21

A meteorological report for the Mount Hopkins Observatory - 1968 - 1969

Meteorological data for Mt. Hopkins Observatory for 1968 and 196

Conservative evaluation of the uncertainty in the LAGEOS-LAGEOS II Lense-Thirring test

We deal with the test of the general relativistic gravitomagnetic Lense-Thirring effect currently ongoing in the Earth's gravitational field with the combined nodes \Omega of the laser-ranged geodetic satellites LAGEOS and LAGEOS II. One of the most important source of systematic uncertainty on the orbits of the LAGEOS satellites, with respect to the Lense-Thirring signature, is the bias due to the even zonal harmonic coefficients J_L of the multipolar expansion of the Earth's geopotential which account for the departures from sphericity of the terrestrial gravitational potential induced by the centrifugal effects of its diurnal rotation. The issue addressed here is: are the so far published evaluations of such a systematic error reliable and realistic? The answer is negative. Indeed, if the difference \Delta J_L among the even zonals estimated in different global solutions (EIGEN-GRACE02S, EIGEN-CG03C, GGM02S, GGM03S, ITG-Grace02, ITG-Grace03s, JEM01-RL03B, EGM2008, AIUB-GRACE01S) is assumed for the uncertainties \delta J_L instead of using their more or less calibrated covariance sigmas \sigma_{J_L}, it turns out that the systematic error \delta\mu in the Lense-Thirring measurement is about 3 to 4 times larger than in the evaluations so far published based on the use of the sigmas of one model at a time separately, amounting up to 37% for the pair EIGEN-GRACE02S/ITG-Grace03s. The comparison among the other recent GRACE-based models yields bias as large as about 25-30%. The major discrepancies still occur for J_4, J_6 and J_8, which are just the zonals the combined LAGEOS/LAGOES II nodes are most sensitive to.Comment: LaTex, 12 pages, 12 tables, no figures, 64 references. To appear in Central European Journal of Physics (CEJP

Few Skewed Disks Found in First Closure-Phase Survey of Herbig Ae/Be stars

Using the 3-telescope IOTA interferometer on Mt. Hopkins, we report results from the first near-infrared (lambda=1.65 mu) closure-phase survey of Young Stellar Objects (YSOs). These closure phases allow us to unambiguously detect departures from centrosymmetry (i.e., skew) in the emission pattern from YSO disks on the scale of ~4 milliarcseconds, expected from generic ``flared disk'' models. Six of fourteen targets showed small, yet statistically-significant, non-zero closure phases, with largest values from the young binary system MWC 361-A and the (pre-main sequence?) Be star HD 45677. Our observations are quite sensitive to the vertical structure of the inner disk and we confront the predictions of the ``puffed-up inner wall'' models of Dullemond, Dominik, and Natta (DDN). Our data support disks models with curved inner rims because the expected emission appear symmetrically-distributed around the star over a wide range of inclination angles. In contrast, our results are incompatible with the models possessing vertical inner walls because they predict extreme skewness (i.e., large closure phases) from the near-IR disk emission that is not seen in our data. In addition, we also present the discovery of mysterious H-band ``halos'' (~5-10% of light on scales 0.01-0.50 arcsec) around a few objects, a preliminary ``parametric imaging'' study for HD 45677, and the first astrometric orbit for the young binary MWC 361-A.Comment: Accepted for publication in Astrophysical Journa

The second set of pulsar discoveries by CHIME/FRB/Pulsar: 14 Rotating Radio Transients and 7 pulsars

The Canadian Hydrogen Mapping Experiment (CHIME) is a radio telescope located in British Columbia, Canada. The large field of view (FOV) of $\sim$ 200 square degrees has enabled the CHIME/FRB instrument to produce the largest FRB catalog to date. The large FOV also allows CHIME/FRB to be an exceptional pulsar and Rotating Radio Transient (RRAT) finding machine, despite saving only the metadata information of incoming Galactic events. We have developed a pipeline to search for pulsars/RRATs using DBSCAN, a clustering algorithm. Output clusters are then inspected by a human for pulsar/RRAT candidates and follow-up observations are scheduled with the more sensitive CHIME/Pulsar instrument. The CHIME/Pulsar instrument is capable of a near-daily search mode observation cadence. We have thus developed the CHIME/Pulsar Single Pulse Pipeline to automate the processing of CHIME/Pulsar search mode data. We report the discovery of 21 new Galactic sources, with 14 RRATs, 6 regular slow pulsars and 1 binary system. Owing to CHIME/Pulsar's daily observations we have obtained timing solutions for 8 of the 14 RRATs along with all the regular pulsars. This demonstrates CHIME/Pulsar's ability at finding timing solutions for transient sources

Eosinophils Are Important for Protection, Immunoregulation and Pathology during Infection with Nematode Microfilariae

Eosinophil responses typify both allergic and parasitic helminth disease. In helminthic disease, the role of eosinophils can be both protective in immune responses and destructive in pathological responses. To investigate whether eosinophils are involved in both protection and pathology during filarial nematode infection, we explored the role of eosinophils and their granule proteins, eosinophil peroxidase (EPO) and major basic protein-1 (MBP-1), during infection with Brugia malayi microfilariae. Using eosinophil-deficient mice (PHIL), we further clarify the role of eosinophils in clearance of microfilariae during primary, but not challenge infection in vivo. Deletion of EPO or MBP-1 alone was insufficient to abrogate parasite clearance suggesting that either these molecules are redundant or eosinophils act indirectly in parasite clearance via augmentation of other protective responses. Absence of eosinophils increased mast cell recruitment, but not other cell types, into the broncho-alveolar lavage fluid during challenge infection. In addition absence of eosinophils or EPO alone, augmented parasite-induced IgE responses, as measured by ELISA, demonstrating that eosinophils are involved in regulation of IgE. Whole body plethysmography indicated that nematode-induced changes in airway physiology were reduced in challenge infection in the absence of eosinophils and also during primary infection in the absence of EPO alone. However lack of eosinophils or MBP-1 actually increased goblet cell mucus production. We did not find any major differences in cytokine responses in the absence of eosinophils, EPO or MBP-1. These results reveal that eosinophils actively participate in regulation of IgE and goblet cell mucus production via granule secretion during nematode-induced pathology and highlight their importance both as effector cells, as damage-inducing cells and as supervisory cells that shape both innate and adaptive immunity

Proposed host galaxies of repeating fast radio burst sources detected by CHIME/FRB

We present a search for host galaxy associations for the third set of repeating fast radio burst (FRB) sources discovered by the CHIME/FRB Collaboration. Using the ~1 arcmin CHIME/FRB baseband localizations and probabilistic methods. We identify potential host galaxies of two FRBs, 20200223B and 20190110C at redshifts of 0.06024(2) and 0.12244(6), respectively. We also discuss the properties of a third marginal candidate host galaxy association for FRB 20191106C with a host redshift of 0.10775(1). The three putative host galaxies are all relatively massive, fall on the standard mass-metallicity relationship for nearby galaxies, and show evidence of ongoing star formation. They also all show signatures of being in a transitional regime, falling in the "green valley" which is between the bulk of star-forming and quiescent galaxies. The plausible host galaxies identified by our analysis are consistent with the overall population of repeating and non-repeating FRB hosts while increasing the fraction of massive and bright galaxies. Coupled with these previous host associations, we identify a possible excess of FRB repeaters whose host galaxies have M_u - M_r colors redder than the bulk of star-forming galaxies. Additional precise localizations are required to confirm this trend.Comment: 11 pages, submitted to AAS journal

Multiwavelength Constraints on the Origin of a Nearby Repeating Fast Radio Burst Source in a Globular Cluster

Since fast radio bursts (FRBs) were discovered, their precise origins have remained a mystery. Multiwavelength observations of nearby FRB sources provide one of the best ways to make rapid progress in our understanding of the enigmatic FRB phenomenon. We present results from a sensitive, broadband multiwavelength X-ray and radio observational campaign of FRB 20200120E, the closest known extragalactic repeating FRB source. At a distance of 3.63 Mpc, FRB 20200120E resides in an exceptional location, within a ~10 Gyr-old globular cluster in the M81 galactic system. We place deep limits on both the persistent X-ray luminosity and prompt X-ray emission at the time of radio bursts from FRB 20200120E, which we use to constrain possible progenitors for the source. We compare our results to various classes of X-ray sources and transients. In particular, we find that FRB 20200120E is unlikely to be associated with: ultraluminous X-ray bursts (ULXBs), similar to those observed from objects of unknown origin in other extragalactic globular clusters; giant flares, like those observed from Galactic and extragalactic magnetars; or most intermediate flares and very bright short X-ray bursts, similar to those seen from magnetars in the Milky Way. We show that FRB 20200120E is also unlikely to be powered by a persistent or transient ultraluminous X-ray (ULX) source or a young, extragalactic pulsar embedded in a Crab-like nebula. We also provide new constraints on the compatibility of FRB 20200120E with accretion-based FRB models involving X-ray binaries and models that require a synchrotron maser process from relativistic shocks to generate FRB emission. These results highlight the power that multiwavelength observations of nearby FRBs can provide for discriminating between potential FRB progenitor models.Comment: 58 pages, 10 figures, 7 tables, submitte

Evaluation of Needle Exchange Programs

Needle exchange programs exist in every major population area in the United States and in many other countries. Some operate legally under emergency health decrees issued by local departments of health, with the stated intention of risk reduction through the removal of used injection equipment from use by injection drug users. It is theorized that this results in a reduced transmission of human immunodeficiency virus, hepatitis, and, possibly, other blood-borne diseases. Needle exchange programs also offer access to drug treatment programs for the participants. It is a difficult but necessary task to evaluate these programs. This article examines examples of evaluations attempted in the past and discusses the challenges of such evaluations. Experimental evaluations, economic program analysis, legal aspects, and risk–benefit assessment along with ethical aspects are considered. An outline of program evaluation is proposed. Needle exchange programs offer an opportunity to encourage risk reduction and to offer counseling and access to health care for individuals at high risk. It is essential that such programs demonstrate their effectiveness. Assumptions of efficacy are insufficient for health care in the twenty-first century