15,459 research outputs found

    Mitochondrial Dynamics at the Interface of Immune Cell Metabolism and Function

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    Immune cell differentiation and function are crucially dependent on specific metabolic programs dictated by mitochondria, including the generation of ATP from the oxidation of nutrients and supplying precursors for the synthesis of macromolecules and post-translational modifications. The many processes that occur in mitochondria are intimately linked to their morphology that is shaped by opposing fusion and fission events. Exciting evidence is now emerging that demonstrates reciprocal crosstalk between mitochondrial dynamics and metabolism. Metabolic cues can control the mitochondrial fission and fusion machinery to acquire specific morphologies that shape their activity. We review the dynamic properties of mitochondria and discuss how these organelles interlace with immune cell metabolism and function

    Solutions of the boundary Yang-Baxter equation for ADE models

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    We present the general diagonal and, in some cases, non-diagonal solutions of the boundary Yang-Baxter equation for a number of related interaction-round-a-face models, including the standard and dilute A_L, D_L and E_{6,7,8} models.Comment: 32 pages. Sections 7.2 and 9.2 revise

    Effect of ambient temperature on the human tear film

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    Laminar flow control leading edge glove flight test article development

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    A laminar flow control (LFC) flight test article was designed and fabricated to fit into the right leading edge of a JetStar aircraft. The article was designed to attach to the front spar and fill in approx. 70 inches of the leading edge that are normally occupied by the large slipper fuel tank. The outer contour of the test article was constrained to align with an external fairing aft of the front spar which provided a surface pressure distribution over the test region representative of an LFC airfoil. LFC is achieved by applying suction through a finely perforated surface, which removes a small fraction of the boundary layer. The LFC test article has a retractable high lift shield to protect the laminar surface from contamination by airborne debris during takeoff and low altitude operation. The shield is designed to intercept insects and other particles that could otherwise impact the leading edge. Because the shield will intercept freezing rain and ice, a oozing glycol ice protection system is installed on the shield leading edge. In addition to the shield, a liquid freezing point depressant can be sprayed on the back of the shield

    Interaction-Round-a-Face Models with Fixed Boundary Conditions: The ABF Fusion Hierarchy

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    We use boundary weights and reflection equations to obtain families of commuting double-row transfer matrices for interaction-round-a-face models with fixed boundary conditions. In particular, we consider the fusion hierarchy of the Andrews-Baxter-Forrester models, for which we find that the double-row transfer matrices satisfy functional equations with an su(2) structure.Comment: 48 pages, LaTeX, requires about 79000 words of TeX memory. Submitted to J. Stat. Phy

    Palladium, platinum, and gold distribution in serpentinite seamounts in the Mariana and Izu-Bonin forearcs: evidence from Leg 125 fluids and serpentinites

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    Palladium, platinum, and gold were analyzed for 20 interstitial water samples from Leg 125. No Pd or Pt was detected in fluids from serpentinite muds from Conical Seamount in the Mariana forearc, indicating that low-temperature seawater-peridotite interaction does not mobilize these elements into the serpentinizing fluids to levels above 0.10 parts per billion (ppb) in solution. However, Au may be mobilized in high pH solutions. In contrast, fluids from vitric-rich clays on the flanks of the Torishima Seamount in the Izu-Bonin forearc have Pd values of between 4.0 and 11.8 nmol/L, Pt values between 2.3 and 5.0 nmol/L and Au values between 126.9 and 1116.9 pmol/L. The precious metals are mobilized, and possibly adsorbed onto clay mineral surfaces, during diagenesis and burial of the volcanic-rich clays. Desorption during squeezing of the sediments may produce the enhanced precious metal concentrations in the analyzed fluids. The metals are mobilized in the fluids probably as neutral hydroxide, bisulfide, and ammonia complexes. Pt/Pd ratios are between 0.42 and 2.33, which is much lower than many of the potential sources for Pt and Pd but is consistent with the greater solubility of Pd compared with Pt in most natural low-temperature fluids

    Optimal traps in graphene

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    We transform the two-dimensional Dirac-Weyl equation, which governs the charge carriers in graphene, into a non-linear first-order differential equation for scattering phase shift, using the so-called variable phase method. This allows us to utilize the Levinson Theorem to find zero-energy bound states created electrostatically in realistic structures. These confined states are formed at critical potential strengths, which leads to us posit the use of `optimal traps' to combat the chiral tunneling found in graphene, which could be explored experimentally with an artificial network of point charges held above the graphene layer. We also discuss scattering on these states and find the zero angular momentum states create a dominant peak in scattering cross-section as energy tends towards the Dirac point energy, suggesting a dominant contribution to resistivity.Comment: 11 pages, 5 figure

    Palladium, platinum, and gold distribution in serpentinite seamounts in the Mariana and Izu-Bonin forearcs: evidence from Leg 125 fluids and serpentinites

    No full text
    Palladium, platinum, and gold were analyzed for 20 interstitial water samples from Leg 125. No Pd or Pt was detected in fluids from serpentinite muds from Conical Seamount in the Mariana forearc, indicating that low-temperature seawater-peridotite interaction does not mobilize these elements into the serpentinizing fluids to levels above 0.10 parts per billion (ppb) in solution. However, Au may be mobilized in high pH solutions. In contrast, fluids from vitric-rich clays on the flanks of the Torishima Seamount in the Izu-Bonin forearc have Pd values of between 4.0 and 11.8 nmol/L, Pt values between 2.3 and 5.0 nmol/L and Au values between 126.9 and 1116.9 pmol/L. The precious metals are mobilized, and possibly adsorbed onto clay mineral surfaces, during diagenesis and burial of the volcanic-rich clays. Desorption during squeezing of the sediments may produce the enhanced precious metal concentrations in the analyzed fluids. The metals are mobilized in the fluids probably as neutral hydroxide, bisulfide, and ammonia complexes. Pt/Pd ratios are between 0.42 and 2.33, which is much lower than many of the potential sources for Pt and Pd but is consistent with the greater solubility of Pd compared with Pt in most natural low-temperature fluids
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