1,202 research outputs found

    Low complexity hybrid precoding designs for multiuser mmWave/THz ultra massive MIMO Systems

    Get PDF
    Millimeter-wave and terahertz technologies have been attracting attention from the wireless research community since they can offer large underutilized bandwidths which can enable the support of ultra-high-speed connections in future wireless communication systems. While the high signal attenuation occurring at these frequencies requires the adoption of very large (or the so-called ultra-massive) antenna arrays, in order to accomplish low complexity and low power consumption, hybrid analog/digital designs must be adopted. In this paper we present a hybrid design algorithm suitable for both mmWave and THz multiuser multiple-input multiple-output (MIMO) systems, which comprises separate computation steps for the digital precoder, analog precoder and multiuser interference mitigation. The design can also incorporate different analog architectures such as phase shifters, switches and inverters, antenna selection and so on. Furthermore, it is also applicable for different structures, namely fully-connected structures, arrays of subarrays (AoSA) and dynamic arrays of subarrays (DAoSA), making it suitable for the support of ultra-massive MIMO (UM-MIMO) in severely hardware constrained THz systems. We will show that, by using the proposed approach, it is possible to achieve good trade-offs between spectral efficiency and simplified implementation, even as the number of users and data streams increases.info:eu-repo/semantics/publishedVersio

    The actinomycete Kitasatospora sp. SeTe27, subjected to adaptive laboratory evolution (ALE) in the presence of selenite, varies its cellular morphology, redox stability, and tolerance to the toxic oxyanion

    Get PDF
    The effects of oxyanions selenite (SeO32−) in soils are of high concern in ecotoxicology and microbiology as they can react with mineral particles and microorganisms. This study investigated the evolution of the actinomycete Kitasatospora sp. SeTe27 in response to selenite. To this aim, we used the Adaptive Laboratory Evolution (ALE) technique, an experimental approach that mimics natural evolution and enhances microbial fitness for specific growth conditions. The original strain (wild type; WT) isolated from uncontaminated soil gave us a unique model system as it has never encountered the oxidative damage generated by the prooxidant nature of selenite. The WT strain exhibited a good basal level of selenite tolerance, although its growth and oxyanion removal capacity were limited compared to other environmental isolates. Based on these premises, the WT and the ALE strains, the latter isolated at the end of the laboratory evolution procedure, were compared. While both bacterial strains had similar fatty acid profiles, only WT cells exhibited hyphae aggregation and extensively produced membrane-like vesicles when grown in the presence of selenite (challenged conditions). Conversely, ALE selenite-grown cells showed morphological adaptation responses similar to the WT strain under unchallenged conditions, demonstrating the ALE strain improved resilience against selenite toxicity. Whole-genome sequencing revealed specific missense mutations in genes associated with anion transport and primary and secondary metabolisms in the ALE variant. These results were interpreted to show that some energy-demanding processes are attenuated in the ALE strain, prioritizing selenite bioprocessing to guarantee cell survival in the presence of selenite. The present study indicates some crucial points for adapting Kitasatospora sp. SeTe27 to selenite oxidative stress to best deal with selenium pollution. Moreover, the importance of exploring non-conventional bacterial genera, like Kitasatospora, for biotechnological applications is emphasized

    Aquifer architecture of the Quaternary alluvial succession of the southern lambro basin (Lombardy-Italy)

    Get PDF
    Aquifer stratigraphy of the sector of the Pleistocene - Holocene alluvial plain of Lombardy, run by the Lambro valley system south of Milan, has been reconstructed on the basis of geological mapping at 1:10.000 and subsurface interpretation and correlation of more than 150 among water wells, boreholes and deep excavations. The Middle (?) - Late Pleistocene sedimentary evolution of this sector includes four major progradation cycles of alluvial depositional systems that migrated from the alpine northern side towards the axial palaeo-Po depositional system. These cycles were governed by Pleistocene glacial cycles, in combination with ramp-folding of the San Colombano - Salerano apenninic anticlines and minor uplift of the alpine side. Every major cycle is soled by an erosion surface, and is shaped by minor fining upward sequences. Both major and minor sequences record at first the advance of coarse-grained units (distal braided alluvial fan or sandy braid plain) which fringe-out south-eastwards into meandering fluvial systems, and are replaced upwards by alluvial plain fines, which close the sequences. Physical stratigraphy and geomorphology, analysis of facies associations, characterisation of gravel composition, radiocarbon dating on 4 peat and plant relic samples and findings of transported artefacts allowed the correlation of the four cycles with the regional evolution. The Post Glacial meandering depositional systems of the deeply entrenched Lambro valley system (Unit 4, Holocene; Unit 5, historical), are cut into the braided stream to meandering depositional systems that developed during L.G.M. times, at present outside the Lambro valley (Unit 3, Late Pleistocene). These represent the uppermost aquifer unit, i.e. the phreatic - non saturated zone. The underlying Unit 2 (Late Pleistocene) can be correlated with the Besnate Allogroup, and therefore developed during the corresponding glaciations. It is formed by three stacked sequences, controlled by glacial cycles, which are deeply scoured into the lowermost succession that could be studied (Unit 1 Middle ? - Late Pleistocene ?). It represents the most important and permeable intermediate aquifer unit, that is only partly confined by the flood-plain fines of the uppermost sub-unit 2C

    Prevalence of depressive symptoms among Italian medical students: The multicentre cross-sectional “PRIMES” study

    Get PDF
    Background Four percent of the world’s population suffers from depression, which is a major public health issue. Medical students are at risk, as their depressive symptoms (DS) prevalence is reported to be approximately 27% worldwide. Since few data on Italian medical students exist, this study aimed to estimate their DS prevalence and assess risk and protective factors. Methods The PRIMES was a multicentre cross-sectional study performed in 12 Italian medical schools. Questionnaires were self-reported and included 30 sociodemographic items and the Beck Depression Inventory-II (BDI-II). The primary outcome was the presence of DS (BDI-II score�14). The main analyses were chi-squared tests and multivariable logistic regressions with a p-value<0.05 considered significant. Results The number of collected questionnaires was 2,513 (117 BDI-II incomplete). Females accounted for 61.3% of the respondents, and the median age was 22 years (IQR = 4). The prevalence of DS was 29.5%. Specifically, 14.0% had mild depression, 11.1% had moder- ate depression, and 4.5% had severe depression. The main risk factors for DS were age, being female, bisexual/asexual orientation, living with partner/housemates, poor economic status (worsened by living far from home), less than 90 min of weekly exercise, relatives with psychiatric disorders, personal chronic disease, judging medical school choice nega- tively, unsatisfying friendships with classmates, competitive and hostile climate among classmates, thinking that medical school hinders specific activities and being worried about not measuring up to the profession. Protective factors included family cohesion, hobbies, intellectual curiosity as a career motivation and no worries about the future. Conclusion Italian medical students are at high risk of reporting DS, similar to the global population of medical students’. Medical schools must make efforts to implement preventive and treat- ment interventions by offering counselling and working on modifiable factors, such as life- style and learning climate
    corecore