Influence of cross section geometry on the confinement of reinforced concrete columns with CFRP composites

Comunicação apresentada em International Symposium Polymers in Concrete (ISPIC 2006), Guimarães, 2006Confinement effectiveness of externally bonded FRP jackets depends on different parameters namely type of concrete, steel reinforcement, FRP jacket stiffness (type of FRP, number of plies and design of wrap), shape of cross section, radius of corners for non-circular sections, and loading conditions. In order to investigate the effect of some of these parameters on the axial behavior of columns under compression and to quantify the level of confinement exerted on the concrete core, an experimental program has been developed. The experimental research consisted of a sequence of axial compressive tests on cylinders and square prisms. Prisms were divided into three representative groups: sharpedged sections and sections with rounded corners with corner radii equal to either 20mm or 38mm. The results presented in this paper are for the columns which were wrapped with two plies of unidirectional carbon fibers

Changing Scales: Greenways From Region To Place – The Case Of The Algarve, Portugal.

This article aims to reflect and debate around the operational value of the greenway concept, while paramount instrument for landscape planning and management, divided in two parts. The first one focuses on the definition and evolution of the greenway concept and its relations with other fundamental concepts, such as continuum naturale, ecological structure and green infrastructure. In this conceptual approach, the main scope is the importance of accurate criteria definition for greenway design, considering the transposition between different scales. In the latter part of the article, the case study of the Algarve, southern Portugal, is presented, where greenway design occurs at a regional scale, integrated in a system designated as Estrutura Regional de Protecção e Valorização Ambiental (ERPVA, Regional Environmental Protection and Valorization Structure), within the Plano Regional de Ordenamento do Território do Algarve (PROT-Algarve, Territorial Management Plan of the Algarve), setting guidelines for the transposition for the municipal level landscape management instruments. The goal is to assess the challenges, opportunities and constraints enclosed in the scale adaptation process, namely through the analysis of the revision processes of the Planos Directores Municipais (PDM, municipal master plans) of Lagoa and Silves

Probabilistic clustering of interval data

In this paper we address the problem of clustering interval data, adopting a model-based approach. To this purpose, parametric models for interval-valued variables are used which consider configurations for the variance-covariance matrix that take the nature of the interval data directly into account. Results, both on synthetic and empirical data, clearly show the well-founding of the proposed approach. The method succeeds in finding parsimonious heterocedastic models which is a critical feature in many applications. Furthermore, the analysis of the different data sets made clear the need to explicitly consider the intrinsic variability present in interval data.info:eu-repo/semantics/publishedVersio

Identifying Special Structures in Interval-Data via Model-Base Clustering

In this paper we present a model-based approach to the clustering of interval data building on recently proposed parametric models. These methods consider configurations for the variance-covariance matrix that take the nature of the interval data directly into account. The proposed framework relies on parametrizations considering the inherent variability of the relevant data units and the relation that may exist between this variability and the corresponding value levels. Using both synthetic and real data sets the pertinence of the proposed methodology is shown, as the method effectively selects heterocedastic models with restricted covariance structures when they are the most suitable, even in situations with limited information. Moreover, considering special configurations of the variance-covariance matrix, adapted to nature of interval data, proves to be the adequate approach. The presented study also makes clear the need to consider both the information about position (conveyed by the MidPoints) and intrinsic variability (conveyed by the Log-Ranges) when analysing interval data.info:eu-repo/semantics/publishedVersio

An analysis of energy consumption for transportation in Portuguese cities using artificial neural networks

Empirical studies carried out in several parts of the world have highlighted the existence of a strong relationship between the physical planning of cities and energy use for transportation. Despite the economic and environmental costs produced by urban sprawl, several countries have not yet started to study the phenomenon in order to better understand it and to somehow control it. Thus, this study tries to bring a contribution to the subject through an analysis of the situation found in some of the main Portuguese cities, which however do not include Lisbon and Oporto. The main objective of this work is to identify the variables related to physical aspects of the cities and socioeconomic characteristics of urbanized areas in Portugal that significantly influence energy consumption for transportation. After the spatial and socioeconomic data were comb ined in a single database, they were analyzed using Artificial Neural Network models, in order to identify variables that are relevant to energy consumption for transportation, along with their relative weights. The results found in the current study confirmed the trend observed in several countries worldwide, in which the characteristics of urban form and population distribution played an important role influencing energy use for transportation

Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNF and IFN

In cutaneous leishmaniasis, Leishmania amazonensis activates macrophage double-stranded, RNA-activated protein kinase R (PKR) to promote parasite growth. In our study, Leishmania major grew normally in RAW cells, RAW-expressing dominant-negative PKR (PKR-DN) cells, and macrophages of PKR-knockout mice, revealing that PKR is dispensable for L. major growth in macrophages. PKR activation in infected macrophages with poly I:C resulted in parasite death. Fifty percent of L. major-knockout lines for the ecotin-like serine peptidase inhibitor (ISP2; Δisp2/isp3), an inhibitor of neutrophil elastase (NE), died in RAW cells or macrophages from 129Sv mice, as a result of PKR activation. Inhibition of PKR or NE or neutralization of Toll-like receptor 4 or 2(TLR4 or TLR2) prevented the death of Δisp2/isp3. Δisp2/isp3 grew normally in RAW-PKR-DN cells or macrophages from 129Sv pkr−/−, tlr2−/−, trif−/−, and myd88−/− mice, associating NE activity, PKR, and TLR responses with parasite death. Δisp2/isp3 increased the expression of mRNA for TNF-α by 2-fold and of interferon β (IFNβ) in a PKR-dependent manner. Antibodies to TNF-α reversed the 95% killing by Δisp2/isp3, whereas they grew normally in macrophages from IFN receptor–knockout mice. We propose that ISP2 prevents the activation of PKR via an NE-TLR4-TLR2 axis to control innate responses that contribute to the killing of L. major.—Faria, M. S., Calegari-Silva, T. C., de Carvalho Vivarini, A., Mottram, J. C., Lopes, U. G., Lima, A. P. C. A. Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNFα and IFNβ