Using Head, Heart and Hands to (De)construct Community Development in Tijuana, Mexico

Short-term international service-learning immersions can provide accessible ways for students to experience other countries and cultures, creating the possibility for development of the whole person in a global context. These programs often involve the physical labor of students, through building houses, serving food to migrants, and the like. As Peter-Hans Kolvenbach, S.J. has observed, such service can be valued by the recipient community and for the participating student, and can challenge the mind to change. But how can such programs increase their value proposition in support of the organization’s mission? In other words, how might we employ minds as well as hands and hearts in other ways that promote justice work? This article describes an immersion program, academic course, and community-based research effort forged over a 25-year relationship between Seattle University and Esperanza, a non-governmental organization that focuses on community development, micro finance, and affordable housing in Tijuana, Mexico. Using the Ignatian pedagogical paradigm, a constellation of stakeholders—faculty, staff, students, and community partners—reflect on the partnership and the enhancements to a long-standing collaborative effort. Lessons learned are offered. Ultimately, we conclude that long-term reciprocal benefits can be achieved while also inviting participants to deepen their aspirations for social change in a global context

A photo- and electrochemically-active porphyrin–fullerene dyad electropolymer

A hole- and electron-conducting polymer has been prepared by electropolymerization of aporphyrin–fullerene monomer. The porphyrin units are linked by aminophenyl groups to form a linear chain in which the porphyrin is an integral part of the polymer backbone. The absorption spectrum of a film formed on indium-tin-oxide-coated glass resembles that of a model porphyrin–fullerene dyad, but with significant peak broadening. The film demonstrates a first oxidation potential of 0.75 V vs. SCE, corresponding to oxidation of the porphyrin polymer, and a first reduction potential of -0.63 V vs. SCE, corresponding to fullerene reduction. Time-resolved fluorescence studies show that the porphyrin first excited singlet state is strongly quenched by photoinduced electron transfer to fullerene. Transient absorption investigations reveal that excitation generates mobile charge carriers that recombine by both geminate and nongeminate pathways over a large range of time scales. Similar studies on a related polymer that lacks the fullerene component show complex, laser-intensity-dependent photoinduced electron transfer behavior. The properties of the porphyrin–fullerene electropolymer suggest that it maybe useful in organic photovoltaic applications, wherein light absorption leads to charge separationwithin picoseconds in a “molecular heterojunction” with no requirement for exciton migration.Fil: Gervaldo, Miguel Andres. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Investigaciones en Tecnologías Energéticas y Materiales Avanzados. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Tecnologías Energéticas y Materiales Avanzados; ArgentinaFil: Liddell, Paul A.. Arizona State University; Estados UnidosFil: Kodis, Gerdenis. Arizona State University; Estados UnidosFil: Brennan, Bradley J.. Arizona State University; Estados UnidosFil: Johnson, Christopher R.. Arizona State University; Estados UnidosFil: Bridgewater, James W.. Arizona State University; Estados UnidosFil: Moore, Ana L.. Arizona State University; Estados UnidosFil: Moore, Thomas A.. Arizona State University; Estados UnidosFil: Gust, Devens. Arizona State University; Estados Unido

Football: a counterpoint to the procession of pain on the Western Front, 1914-1918?

In this article, three artworks of the First World War containing images of recreational football are analysed. These three images, In the Wings of the Theatre of War, Artillery Men at Football and Gassed, span the war from its beginning to its conclusion and are discussed in relationship to the development of recreational football in the front-line area, the evolving policies of censorship and propaganda and in consideration of the national mood in Britain. The paper shows how football went from being a spontaneous and improvised pastime in the early stages of the war to a well organized entertainment by war’s end. The images demonstrate how the war was portrayed as a temporary affair by a confident nation in 1914 to a more resigned acceptance of a semi-permanent event to be endured by 1918; however, all three artworks show that the sporting spirit, and hence the fighting spirit, of the British soldier was intact

Starlit: Privacy-Preserving Federated Learning to Enhance Financial Fraud Detection

Federated Learning (FL) is a data-minimization approach enabling collaborative model training across diverse clients with local data, avoiding direct data exchange. However, state-of-the-art FL solutions to identify fraudulent financial transactions exhibit a subset of the following limitations. They (1) lack a formal security definition and proof, (2) assume prior freezing of suspicious customers' accounts by financial institutions (limiting the solutions' adoption), (3) scale poorly, involving either $O(n^2)$ computationally expensive modular exponentiation (where $n$ is the total number of financial institutions) or highly inefficient fully homomorphic encryption, (4) assume the parties have already completed the identity alignment phase, hence excluding it from the implementation, performance evaluation, and security analysis, and (5) struggle to resist clients' dropouts. This work introduces Starlit, a novel scalable privacy-preserving FL mechanism that overcomes these limitations. It has various applications, such as enhancing financial fraud detection, mitigating terrorism, and enhancing digital health. We implemented Starlit and conducted a thorough performance analysis using synthetic data from a key player in global financial transactions. The evaluation indicates Starlit's scalability, efficiency, and accuracy

ZnII(atsm) is protective in amyotrophic lateral sclerosis model mice via a copper delivery mechanism

AbstractMutations in the metalloprotein Cu,Zn-superoxide dismutase (SOD1) cause approximately 20% of familial cases of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease for which effective therapeutics do not yet exist. Transgenic rodent models based on over-expression of mutant SOD1 have been developed and these have provided opportunity to test new therapeutic strategies and to study the mechanisms of mutant SOD1 toxicity. Although the mechanisms of mutant SOD1 toxicity are yet to be fully elucidated, incorrect or incomplete metallation of SOD1 confers abnormal folding, aggregation and biochemical properties, and improving the metallation state of SOD1 provides a viable therapeutic option. The therapeutic effects of delivering copper (Cu) to mutant SOD1 have been demonstrated recently. The aim of the current study was to determine if delivery of zinc (Zn) to SOD1 was also therapeutic. To investigate this, SOD1G37R mice were treated with the metal complex diacetyl-bis(4-methylthiosemicarbazonato)zincII [ZnII(atsm)]. Treatment resulted in an improvement in locomotor function and survival of the mice. However, biochemical analysis of spinal cord tissue collected from the mice revealed that the treatment did not increase overall Zn levels in the spinal cord nor the Zn content of SOD1. In contrast, overall levels of Cu in the spinal cord were elevated in the ZnII(atsm)-treated SOD1G37R mice and the Cu content of SOD1 was also elevated. Further experiments demonstrated transmetallation of ZnII(atsm) in the presence of Cu to form the Cu-analogue CuII(atsm), indicating that the observed therapeutic effects for ZnII(atsm) in SOD1G37R mice may in fact be due to in vivo transmetallation and subsequent delivery of Cu