Glaciochemistry of polar ice cores: A review

Human activities have already modified the chemical composition of the natural atmosphere even in very remote regions of the world. The study of chemical parameters stored in solid precipitation and accumulated on polar ice sheets over the last several hundred thousand years provides a unique tool for obtaining information on the composition of the preindustrial atmosphere and its natural variability over the past. This paper deals with the chemistry of polar ice focused on the soluble mineral (Na+, NH4+, K+, Ca++, Mg++, H+, F−, Cl−, NO3−, SO4−−, and H2O2) and organic (methanesulfonate (CH3SO3−), formate (HCOO−), acetate (CH3COO−), and formaldehyde (HCHO)) species and their interpretation in terms of past atmospheric composition (aerosols and water soluble gaseous species). We discuss ice core dating, the difficulties connected with trace measurements, and the significance of the ionic composition of snow. We examine temporal (from the last decades back to the last climatic cycle) and spatial (including examples from coastal as well as central areas of Greenland and Antarctica) variations in the ionic budget of the precipitation and evaluate ice core studies in terms of the chemical composition of our past atmosphere. We review (1) how Greenland and Antarctic ice cores that span the last few centuries have provided information on the impact of human activities and (2) how the chemistry of deep ice cores provides information on various past natural phenomena such as climatic variations (glacial-interglacial changes, El Niño), volcanic eruptions, and large boreal forest fires

Control of anthocyanin biosynthesis pathway gene expression by eutypine, a toxin from Eutypa lata, in grape cell tissue cultures

Eutypine, 4-hydroxy-3-(3-methyl-3-butene-1-ynyl) benzaldehyde, is a toxin produced by Eutypa lata, the causal agent of Eutypa dieback in grapevine. The effect of the toxin on anthocyanin synthesis has been investigated in Vitis vinifera cv. Gamay cell cultures. At concentrations higher than 200 μmol/L, eutypine reduced anthocyanin accumulation in cells. The reduction in anthocyanin accumulation was proportional to the eutypine concentrations and HPLC analysis showed that eutypine affected the levels of all anthocyanins. The effect of eutypine application on the expression of five genes of the anthocyanin biosynthesis pathway, including chalcone synthase (CHS), flavonone-3-hydroxylase (F3H), dihydroflavonol 4-reductase (DFR), leucoanthocyanidin dioxygenase (LDOX), and UDP glucose- flavonoid 3-O-glucosyl transferase (UFGT) was determined. Expression of CHS, F3H, DFR and LDOX was not affected by the addition of eutypine to grapevine cell cultures. In contrast, expression of the UFGT gene was dramatically inhibited by the toxin. These results suggest that in grapevine cell cultures, eutypine strongly affects anthocyanin accumulation by inhibiting UFGT gene expression. The mechanism of action of eutypine is discussed

Motivational State Does Not Affect All-Out Short Duration Exercise Performance

Introduction: The preferred motivational state (telic or paratelic), i.e., dominance, has been linked to the type of activity sports people participate in. As such, positive or negative performance may occur if there is a mismatch between the activity and the required state. This study set out to examine the effects of altering telic or paratelic motivational states and thus induce the ?misfit effect? in order to quantify the influences on emotions and performance during allout, short duration cycle performance. Methods: Based on paratelic dominance scale (PDS) scores participants completed the Wingate anaerobic test (WAT) on two separate occasions in their preferred and non-preferred motivational state. Special video display method was used to manipulate participants to their non-preferred motivational state and verified via the telic state measure (TSM) test prior to performing the Wingate test (WT). Changes in emotion and stress levels were recorded using the tension and effort stress inventory (TESI) along with heart rate variability (HRV) data obtained from electrocardiogram (ECG). Peak power (PP), mean power (MP) and fatigue index (FI) obtained from the WT were used to assess all-out athletic performance. Results: The main findings show that there was no link between dominant motivational state and anaerobic cycle performance (p>0.05) and that successful manipulation of motivational state (p<0.05) did not influence perceived levels or physiological levels of stress (p>0.05) and did not affect all-out, short duration cycle performance (p<0.05). Conclusion: As such, coaches, support staff and athletes do not have to worry about a particular state in regards to telic or paratelic in an acute time frame, as long as the athlete?s arousal levels and emotional conditions are optimal.publishersversionPeer reviewe

Greenland ice core “signal” characteristics: An expanded view of climate change

The last millenium of Earth history is of particular interest because it documents the environmental complexities of both natural variability and anthropogenic activity. We have analyzed the major ions contained in the Greenland Ice Sheet Project 2 (GISP 2) ice core from the present to ∼674 A.D. to yield an environmental reconstruction for this period that includes a description of nitrogen and sulfur cycling, volcanic emissions, sea salt and terrestrial influences. We have adapted and extended mathematical procedures for extracting sporadic (e.g., volcanic) events, secular trends, and periodicities found in the data sets. Finally, by not assuming that periodic components (signals) were “stationary” and by utilizing evolutionary spectral analysis, we were able to reveal periodic processes in the climate system which change in frequency, “turn on,” and “turn off” with other climate transitions such as\u27that between the little ice age and the medieval warm period

Improving Simulations of MPI Applications Using A Hybrid Network Model with Topology and Contention Support

Proper modeling of collective communications is essential for understanding the behavior of medium-to-large scale parallel applications, and even minor deviations in implementation can adversely affect the prediction of real-world performance. We propose a hybrid network model extending LogP based approaches to account for topology and contention in high-speed TCP networks. This model is validated within SMPI, an MPI implementation provided by the SimGrid simulation toolkit. With SMPI, standard MPI applications can be compiled and run in a simulated network environment, and traces can be captured without incurring errors from tracing overheads or poor clock synchronization as in physical experiments. SMPI provides features for simulating applications that require large amounts of time or resources, including selective execution, ram folding, and off-line replay of execution traces. We validate our model by comparing traces produced by SMPI with those from other simulation platforms, as well as real world environments.Une bonne modélisation des communications collective est indispensable à la compréhension des performances des applications parallèles et des différences, même minimes, dans leur implémentation peut drastiquement modifier les performances escomptées. Nous proposons un modèle réseau hybrid étendant les approches de type LogP mais permettant de rendre compte de la topologie et de la contention pour les réseaux hautes performances utilisant TCP. Ce modèle est mis en oeuvre et validé au sein de SMPI, une implémentation de MPI fournie par l'environnement SimGrid. SMPI permet de compiler et d'exécuter sans modification des applications MPI dans un environnement simulé. Il est alors possible de capturer des traces sans l'intrusivité ni les problème de synchronisation d'horloges habituellement rencontrés dans des expériences réelles. SMPI permet également de simuler des applications gourmandes en mémoire ou en temps de calcul à l'aide de techniques telles l'exécution sélective, le repliement mémoire ou le rejeu hors-ligne de traces d'exécutions. Nous validons notre modèle en comparant les traces produites à l'aide de SMPI avec celles de traces d'exécution réelle. Nous montrons le gain obtenu en les comparant également à celles obtenues avec des modèles plus classiques utilisés dans des outils concurrents

Model predictive current control based on a generalised adjacent voltage vectors approach for multilevel inverters

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163810/1/pel2bf01679.pd

Homozygosity at the MTL locus in clinical strains of Candida albicans: Karyotypic rearrangments and tetraploid formation

One hundred and twenty Candida albicans clinical isolates from the late 1980s and early 1990s were examined for homosygosity at the MTL locus. Of these, 108 were heterozygous (MTLa/MTLα), whereas seven were MTLa and five were MTLα. Five of the homozygous isolates were able to switch to the opaque cell morphology, while opaque cells were not detectable among the remaining seven. Nevertheless, all but one of the isolates homozygous at the MTL locus were shown to mate and to yield cells containing markers from both parents; the non-mater was found to have a frameshift in the MTLα1 gene. In contrast to Saccharomyces cerevisiae, C. albicans homozygotes with no active MTL allele failed to mate rather than mating as a cells. There was no correlation between homoxygosity and fluconazole resistance, mating and fluconazole resistance or switching and fluconazole resistance, in part because most of the strains were isolated before the widespread use of this antifungal agent, and only three were in fact drug resistant Ten of the 12 homozygotes had rearranged karyotypes involving one or more homologue of chromosomes 4, 5, 6 and 7. We suggest that karyotypic rearrangement, drug resistance and homozygosity come about as the result of induction of hyperrecombination during the infection process; hence, they tend to occur together, but each is the independent result of the same event. Furthermore, as clinical strains can mate and form tetraploids, mating and marker exchange are likely to be a significant part of the life cycle of C. albicans in vivo

The CMS Integration Grid Testbed

The CMS Integration Grid Testbed (IGT) comprises USCMS Tier-1 and Tier-2 hardware at the following sites: the California Institute of Technology, Fermi National Accelerator Laboratory, the University of California at San Diego, and the University of Florida at Gainesville. The IGT runs jobs using the Globus Toolkit with a DAGMan and Condor-G front end. The virtual organization (VO) is managed using VO management scripts from the European Data Grid (EDG). Gridwide monitoring is accomplished using local tools such as Ganglia interfaced into the Globus Metadata Directory Service (MDS) and the agent based Mona Lisa. Domain specific software is packaged and installed using the Distrib ution After Release (DAR) tool of CMS, while middleware under the auspices of the Virtual Data Toolkit (VDT) is distributed using Pacman. During a continuo us two month span in Fall of 2002, over 1 million official CMS GEANT based Monte Carlo events were generated and returned to CERN for analysis while being demonstrated at SC2002. In this paper, we describe the process that led to one of the world's first continuously available, functioning grids.Comment: CHEP 2003 MOCT01