2,871 research outputs found
Locus of Control and the Age Difference in Free Recall From Episodic Memory
The authors investigated the relation of locus of control (LOC) to age differences in free-recall memory performance. Older and younger participants completed P. C. Duttweiler\u27s (1984) Internal Control Index (ICI) and subsequently performed free-recall memory tasks. Compared with the younger participants, the older participants exhibited poorer recall with more intrusions and uncorrected repetition errors as well as reduced categorical clustering. For the older participants with less internal LOC, recall proportion and item-pair associative recall clustering were lower than for the older participants with more internal LOC. By contrast, the younger participants did not exhibit any LOC effects in their recall performance. The results suggest that a differential memory organization deficit may underlie the age differences in free recall among individuals varying in LOC when they are performing an intentional learning task. This deficit is discussed in terms of a reduced-inhibition account of cognitive aging
Distributions of the perceptual switches associated with viewing ambiguous stimuli
The ambiguous Necker cube stimulus appears to switch between two alternative perspectives, 'cube-up' and 'cube-down', such that the inter-switch interval gives percept duration. Percept frequency, plotted as a function of duration, is modelled by a gamma distribution, and the model fit is improved by discarding arbitrarily durations greater than three standard deviations above the mean (Borsellino et al, 1972 Kybernetik 10 139 - 144). Alternatively, good fits can be achieved by discarding the 'dead period' at the beginning of the distribution that represents the observer's decision time between a switch and the subsequent response with a key press that signals the switch (Martin, 1967 Papers in Psychology 1 2).
Twenty-nine naïve observers recorded switches between cube-up and cube-down percepts. During a total observation period of 10 min, observers recorded up to 300 switches. We found that the best fits were generated with the gamma distribution when the 'dead period' was discarded. Arbitrary trimming of the tail, three standard deviations above the mean, had little impact on goodness-of-fit. This suggests that (i) the perceptual changes can be adequately modelled as a simple stochastic process, and (ii) the modelling is improved by accounting for the decision time between switch and response
Review of best management practices for aquatic vegetation control in stormwater ponds, wetlands, and lakes
Auckland Council (AC) is responsible for the development and operation of a stormwater network across the region to avert risks to citizens and the environment.
Within this stormwater network, aquatic vegetation (including plants, unicellular and filamentous algae) can have both a positive and negative role in stormwater management and water quality treatment. The situations where management is needed to control aquatic vegetation are not always clear, and an inability to identify effective, feasible and economical control options may constrain management initiatives. AC (Infrastructure and Technical Services, Stormwater) commissioned this technical report to provide information for decision- making on aquatic vegetation management with in stormwater systems that are likely to experience vegetation-related issues.
Information was collated from a comprehensive literature review, augmented by knowledge held by the authors. This review identified a wide range of management practices that could be potentially employed. It also demonstrated complexities and uncertainties relating to these options that makes the identification of a best management practice difficult. Hence, the focus of this report was to enable users to screen for potential options, and use reference material provided on each option to confirm the best practice to employ for each situation.
The report identifies factors to define whether there is an aquatic vegetation problem (Section 3.0), and emphasises the need for agreed management goals for control (e.g. reduction, mitigation, containment, eradication). Resources to screen which management option(s) to employ are provided (Section 4.0), relating to the target aquatic vegetation, likely applicability of options to the system being managed, indicative cost, and ease of implementation. Initial screening allows users to shortlist potential control options for further reference (Section 5.0).
Thirty-five control options are described (Section 5.0) in sufficient detail to consider applicability to individual sites and species. These options are grouped under categories of biological, chemical or physical control. Biological control options involve the use of organisms to predate, infect or control vegetation growth (e.g. classical biological control) or manipulate conditions to control algal growth (e.g. pest fish removal, microbial products). Chemical control options involve the use of pesticides and chemicals (e.g. glyphosate, diquat), or the use of flocculants and nutrient inactivation products that are used to reduce nutrient loading, thereby decreasing algal growth. Physical control options involve removing vegetation or algal biomass (e.g. mechanical or manual harvesting), or setting up barriers to their growth (e.g. shading, bottom lining, sediment capping).
Preventative management options are usually the most cost effective, and these are also briefly described (Section 6.0). For example, the use of hygiene or quarantine protocols can reduce weed introductions or spread. Catchment- based practices to reduce sediment and nutrient sources to stormwater are likely to assist in the avoidance of algal and possibly aquatic plant problems. Nutrient removal may be a co-benefit where harvesting of submerged weed biomass is undertaken in stormwater systems. It should also be considered that removal of substantial amounts of submerged vegetation may result in a sudden and difficult-to-reverse s witch to a turbid, phytoplankton dominated state. Another possible solution is the conversion of systems that experience aquatic vegetation issues, to systems that are less likely to experience issues.
The focus of this report is on systems that receive significant stormwater inputs, i.e. constructed bodies, including ponds, amenity lakes, wetlands, and highly-modified receiving bodies. However, some information will have application to other natural water bodies
Cloning and expression of a rat brain interleukin-1beta-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons
Several members of the IL-1beta-converting enzyme (ICE) family of proteases recently have been implicated in the intracellular cascade mediating the apoptotic death of various cell types. It is unclear, however, whether ICE-related proteases are involved in apoptosis of mammalian neurons and, if so, how they are activated. Here we report the cloning of an ICE-related protease (IRP) from rat brain, which displays strong sequence identity to human CPP32. In situ hybridization histochemistry reveals that this IRP mRNA is expressed in neuron-enriched regions of the developing and adult rat brain but is profoundly downregulated in the adult (compared with developing) brain. To investigate whether this IRP is involved in the death of neurons in the developing brain, we studied IRP expression in cultured cerebellar granule neurons. In cultured cerebellar granule neurons, reduction of extracellular K+ reliably induces apoptosis and stimulates overexpression of IRP mRNA. The latter is especially prominent 4 hr after switching from high K+ to low K+ medium. The expression of IRP mRNA was maintained at this level for at least 8 hr and was followed by apoptotic death of these neurons. Induction of IRP mRNA and cell death are blocked completely by adding depolarizing concentrations of K+ </=90 min after switching to low K+ medium (i.e., before the commitment point for apoptosis) and partially blocked by brain-derived neurotrophic factor (BDNF), which also partially rescues granule neurons from low K+-induced apoptosis. In addition, overexpression of IRP cDNA in HeLa cells results in cell death accompanied by strong internucleosomal cleavage of DNA, a typical feature of apoptosis. Finally, we detected cleavage of the putative death substrate poly (ADP-ribose) polymerase (PARP), beginning 8 hr after changing from high K+ to low K+ medium, coinciding with the time course of induced expression of the IRP gene. Our data suggest that transcriptional activation of IRP could be one of the mechanisms involved in the apoptotic death of cerebellar granule neurons
The Otterbein Miscellany - May 1965
https://digitalcommons.otterbein.edu/miscellany/1011/thumbnail.jp
Initiation of antidepressant medication and risk of incident stroke: using the Adult Changes in Thought cohort to address time-varying confounding
Purpose
Depression strongly predicts stroke incidence, suggesting that treating depression may reduce stroke risk. Antidepressant medications, however, may increase stroke risk via direct pathways. Previous evidence on antidepressant medication and stroke incidence is mixed. We evaluated associations between antidepressant use and incident stroke.
Methods
For 2302 Adult Changes in Thought cohort participants with no stroke at study entry, we characterized antidepressant use from pharmacy records, biennial depressive symptoms with a 10-item Centers for Epidemiologic Study–Depression scale, and incident strokes from ICD codes. We used discrete-time survival models with inverse probability weighting to compare stroke risk associated with filling antidepressant prescriptions and by medication category: tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors, or other.
Results
Over an average 8.4-year follow-up, 441 incident strokes occurred. Filling antidepressant medications 3+ times versus 0–2 times predicted 35% increased odds of stroke (OR = 1.35; 95% CI: 0.98, 1.66). Use of TCAs was associated with stroke onset (OR per 10 fills = 1.28; CI: 1.04, 1.57), but use of selective serotonin reuptake inhibitors (OR = 0.98; CI: 0.80, 1.20) or other antidepressants (OR = 0.99; CI: 0.67, 1.45) was not.
Conclusions
Although patients who received antidepressant medication were at higher risk of stroke, this association appeared specific to TCA prescriptions
Impaired microvascular properties in uncomplicated type 1 diabetes identified by Doppler ultrasound of the ocular circulation
The Simplicial Ricci Tensor
The Ricci tensor (Ric) is fundamental to Einstein's geometric theory of
gravitation. The 3-dimensional Ric of a spacelike surface vanishes at the
moment of time symmetry for vacuum spacetimes. The 4-dimensional Ric is the
Einstein tensor for such spacetimes. More recently the Ric was used by Hamilton
to define a non-linear, diffusive Ricci flow (RF) that was fundamental to
Perelman's proof of the Poincare conjecture. Analytic applications of RF can be
found in many fields including general relativity and mathematics. Numerically
it has been applied broadly to communication networks, medical physics,
computer design and more. In this paper, we use Regge calculus (RC) to provide
the first geometric discretization of the Ric. This result is fundamental for
higher-dimensional generalizations of discrete RF. We construct this tensor on
both the simplicial lattice and its dual and prove their equivalence. We show
that the Ric is an edge-based weighted average of deficit divided by an
edge-based weighted average of dual area -- an expression similar to the
vertex-based weighted average of the scalar curvature reported recently. We use
this Ric in a third and independent geometric derivation of the RC Einstein
tensor in arbitrary dimension.Comment: 19 pages, 2 figure
Double-Layer Systems at Zero Magnetic Field
We investigate theoretically the effects of intralayer and interlayer
exchange in biased double-layer electron and hole systems, in the absence of a
magnetic field. We use a variational Hartree-Fock-like approximation to analyze
the effects of layer separation, layer density, tunneling, and applied gate
voltages on the layer densities and on interlayer phase coherence. In agreement
with earlier work, we find that for very small layer separations and low layer
densities, an interlayer-correlated ground state possessing spontaneous
interlayer coherence (SILC) is obtained, even in the absence of interlayer
tunneling. In contrast to earlier work, we find that as a function of total
density, there exist four, rather than three, distinct noncrystalline phases
for balanced double-layer systems without interlayer tunneling. The newly
identified phase exists for a narrow range of densities and has three
components and slightly unequal layer densities, with one layer being spin
polarized, and the other unpolarized. An additional two-component phase is also
possible in the presence of sufficiently strong bias or tunneling. The
lowest-density SILC phase is the fully spin- and pseudospin-polarized
``one-component'' phase discussed by Zheng {\it et al.} [Phys. Rev. B {\bf 55},
4506 (1997)]. We argue that this phase will produce a finite interlayer Coulomb
drag at zero temperature due to the SILC. We calculate the particle densities
in each layer as a function of the gate voltage and total particle density, and
find that interlayer exchange can reduce or prevent abrupt transfers of charge
between the two layers. We also calculate the effect of interlayer exchange on
the interlayer capacitance.Comment: 35 pages, 19 figures included. To appear in PR
- …