Folding of the lysine riboswitch: importance of peripheral elements for transcriptional regulation

The Bacillus subtilis lysC lysine riboswitch modulates its own gene expression upon lysine binding through a transcription attenuation mechanism. The riboswitch aptamer is organized around a single five-way junction that provides the scaffold for two long-range tertiary interactions (loop L2–loop L3 and helix P2–loop L4)—all of this for the creation of a specific lysine binding site. We have determined that the interaction P2–L4 is particularly important for the organization of the ligand-binding site and for the riboswitch transcription attenuation control. Moreover, we have observed that a folding synergy between L2–L3 and P2–L4 allows both interactions to fold at lower magnesium ion concentrations. The P2–L4 interaction is also critical for the close juxtaposition involving stems P1 and P5. This is facilitated by the presence of lysine, suggesting an active role of the ligand in the folding transition. We also show that a previously uncharacterized stem–loop located in the expression platform is highly important for the riboswitch activity. Thus, folding elements located in the aptamer and the expression platform both influence the lysine riboswitch gene regulation

What is structural Exegesis?

Philadelphiavi, 90 p.; 22 c

Early Jewish Hermeneutic in Palestine

Montanaxiii, 344 p.; 21 c

Reading Matthew 28:16-20 with others : how it deconstructs our Western concept of mission

Matthew 28:16-20 is readily read as providing a key teaching about "mission." Its teaching about mission - going, making disciples of all the nations, baptizing them, teaching them to obey Jesus' commands - seems simple and clear enough. Yet, this article aims to deconstruct a Western reading of Mt 28:16-20. This is not in order to denounce the legitimacy of such an interpretation. Deconstructing the Western reading is important in order to help us to recognize that there are other equally legitimate and plausible interpretations, and therefore alternate understandings of its teaching about "mission." In response to the cries of those who suffered from imperialist practices of mission, the article argues that we might want to choose one of the other practices of the mission, one characterized by a respect of the "others" and by a commitment to bringing them a news which will be really good for them

La re-découverte de l'enseignement de Jésus

Patte Daniel. La re-découverte de l'enseignement de Jésus. In: Revue d'histoire et de philosophie religieuses, 52e année n°4,1972. Aperçu sur le passé de quelques minorités religieuses. pp. 499-501

Paul's Faith and the Power of the Gospel : A Structural Introduction to the Pauline Letters

Philadelphiaxxiv, 408 p.; 23 c

Etude de la convection mixte dans une enceinte ventilée

Ce travail concerne les écoulements générés par une source de chaleur et de masse placée dans une enceinte en communication avec l’extérieur par deux ouvertures. Les régimes d’écoulement sont étudiés par des visualisations et des mesures de vitesse et de température. Une étude analytique montre que les écoulements dépendent d’un nombre de Froude calculé à partir des caractéristiques du panache et de l’ouverture haute. Les résultats expérimentaux sont en accord avec cette analyse