Personality Differences in Perception: The role of Incongruity Intolerance and Mental Schemata on Aesthetic Preferences.

ries of classic and modern artistic paintings was examined. The study uses pictures that trigger in the observer the amodal completion, which involves the application and confirmation of already consolidated mental schemata, or the perceptual contradiction, which highlights their non-confirmation, generating incongruity experience. As in a first preliminary study conducted by Bonaiuto, Biasi, Giannini, & Chiodetti (2001) with advertising images, incongruity intolerance levels were assessed with the Building Inclination Test (BIT). Also in this new study, we apply the BIT tool in order to select sixty young adults, divided into three subgroups: 20 very incongruity intolerant participants, 20 very incongruity tolerant ones, and 20 intermediate participants, both genders equally subdivided. Moreover, we selected eighteen colour laser reproductions of classical and modern artistic paintings on A4 paper sheets: six show the predominant completion phenomena, other six are based on clear incongruous situations and the last six show completion phenomena mixed with incongruity. Each participant individually evaluated each illustration on aesthetic and physiognomic aspects, using 11-point scales. Double-blind experimental conditions were assured. The results show that very incongruity intolerant participants highly aesthetically appreciate the completion pictures, but they do not like the incongruent pictures. Differently the very incongruity tolerant participants are able to appreciate all three types of images presented, and attribute positive aesthetic scores also to the incongruent and thus conflictual pictures. The third group of participants is characterized by intermediate level of incongruity intolerance and obtain intermediate scores. Collected data confirm our research paradigm based on the theoretical model of overloading of conflict, and stress the role of the individual level of intolerance of incongruity in the dynamics of aesthetic preferences. This survey also allows to obtain an effect of generalization of the theoretical model through the empirical verification with different types of images

The Effectiveness of Clinical Colloquium Established by the “Drawing Recall” Technique in University Counselling Services for Student Mental Health

An experimental assessment of the effectiveness of university counselling was conducted through the “Stress Drawing Recall” Technique applied before and after a clinical colloquium with 70 uni- versity students of both genders, aged 18 - 35 years, who had requested this service. Another 70 students waiting to undergo the colloquium were interviewed as a control group. Two parallel se- ries of drawings depicting personal stress situations were collected and, after evaluation by three expert judges in “double-blind” conditions, led to establishing five forms of development of the graphic language from the first to second drawing, defined as follows: a) distension, with a reduc- tion in stress indicators and increase in comfort indicators; b) explicit representation of conflict resolution; c) appearance of new elements, with persisting conflict; d) increase in stress indicators; e) invariant or equivalent repetition of the stress drawing. Results showed that students who un- derwent the clinical colloquium (experimental group) changed their stress drawings mainly in the direction of distension and conflict resolution, while the control group had more invariant or equivalent repetition of the stress situation ( X42 = 62.77; p < 0.001). The events depicted in the stress drawings were divided into three categories: a) limited short-term stressful situations due to mainly external agents; b) externally induced stressful situations with intense emotional reso- nance; c) wide-ranging long-lasting stressful situations with great involvement of the self. The participants were divided into: a) very anxious subjects; b) averagely anxious subjects; c) not very anxious subjects, on the basis of their scores on two questionnaires: the MPI (1959) and the STAI (1970). There is a correspondence between the subjects’ level of conflict and extension of the de- picted stress. This confirms the usefulness of the Stress Drawing Recall Technique in psychological counsellin

Design of a novel LOX-1 receptor antagonist mimicking the natural substrate

The lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), the major receptor for oxidized low-density lipoprotein (ox-LDL) in endothelial cells, is overexpressed in atherosclerotic lesions. LOX-1 specific inhibitors, urgently necessary to reduce the rate of atherosclerotic and inflammation processes, are not yet available. We have designed and synthesized a new modified oxidized phospholipid, named PLAzPC, which plays to small scale the ligand-receptor recognition scheme. Molecular docking simulations confirm that PLAzPC disables the hydrophobic component of the ox-LDL recognition domain and allows the interaction of the l-lysine backbone charged groups with the solvent and with the charged/polar residues located around the edges of the LOX-1 hydrophobic tunnel. Binding assays, in a cell model system expressing human LOX-1 receptors, confirm that PLAzPC markedly inhibits ox-LDL binding to LOX-1 with higher efficacy compared to previously identified inhibitors

Lifecycle environmental impact assessment of an overtopping wave energy converter embedded in breakwater systems

Overtopping breakwater systems are among the most promising technologies for exploiting wave energy to generate electricity. They consist in water reservoirs, embedded in piers, placed on top of ramps, higher than sea-level. Pushed by wave energy, seawater fills up the reservoirs and produces electricity by flowing back down through low headhydro turbines. Different overtopping breakwater systems have been tested worldwide in recent years. This study focuses on the Overtopping BReakwater for Energy Conversion (OBREC) system that has been implemented and tested in the harbor of Naples (Italy). The Life Cycle Assessment of a single replicable module of OBREC has been performed for analyzing potential environmental impacts, in terms of Greenhouse Gas Emissions, considering construction, installation, maintenance, and the operational phases. The Carbon Footprint (i.e., mass of CO2eq) to build wave energy converters integrated in breakwater systems has been estimated, more specifically the "environmental investment" (i.e., the share of Carbon Footprint due to the integration of wave energy converter) needed to generate renewable electricity has been assessed. The Carbon Intensity of Electricity (i.e., the ratio between the CO2eq emitted and the electricity produced) has been then assessed in order to demonstrate the profitability and the opportunity to foster innovation in the field of blue energy. Considering the impact for implementing an operational OBREC module (Carbon Footprint = 1.08 t CO2eq; Environmental Investment = 0.48 t CO2eq) and the electricity production (12.6 MWh/year per module), environmental benefits (avoided emissions) would compensate environmental costs (i.e., Carbon Footprint; Environmental Investment) those provided within a range of 25 and 13 months respectively

Colovesical fistulae in the sigmoid diverticulitis

Nella maggior parte dei casi le fistole colovescicali rappresentano una complicanza della malattia diverticolare e sono la tipologia più comune di fistola colodigestiva; meno comuni sono le fistole colovaginali, colocutanee, coloenteriche e colouterine. Nel presente lavoro abbiamo effettuato una review della letteratura riguardante le fistole colovescicali in chirurgia colorettale per diverticolite del sigma. Decriviamo anche due casi che hanno richiesto un trattamento chirurgico, in uno in elezione e nell’altro in urgenza. In entrambi i casi abbiamo eseguito una resezione colica con anastomosi primaria e minimaresezione vesvicale con posizionamento di catetere di Foley in media per 10 giorni

Teaching sustainability within the context of everyday life: steps toward achieving the sustainable development goals through the EUSTEPs module

In a world characterized by Ecological Overshoot, education can nurture sustainability-minded citizens and future leaders to help accelerate the transition towards a one-planet compatible society. Despite the essential role of Higher Education Institutions (HEIs) in contributing to a sustainable society, a holistic understanding of how to incorporate sustainability initiatives into HEIs is still lacking. Given the importance of HEIs in societies and considering the number of students, educators, and staff they host every day, ensuring that sustainability is both taught and practiced within campuses becomes fundamental. To this end, a strategic partnership was created in 2019 to set up the ERASMUS+ project EUSTEPs - Enhancing Universities’ Sustainability Teaching and Practices through Ecological Footprint. Among the main outputs of the project is a teaching module for introducing the sustainability concept to students. This module takes a 360-degree approach to teach sustainability, allowing students to endogenously realize the full complexity of sustainability, in an engaging and captivating manner. This paper thus aims to: 1) present the EUSTEPs Module, its pedagogical approach and structure, and the learning outcomes and competencies students are expected to gain; 2) review the outcomes of its first pilot teaching in four European HEIs, and 3) shed light on how this Module contributes to the development of competences and pedagogical approaches for achieving the Sustainable Development Goals (SDGs). Our findings show that 90% of the students were ‘satisfied’ or ‘very satisfied’ with the Module, rating the Ecological Footprint as the most useful teaching tool among those included in the Module, and appreciated the interactive nature of the proposed teaching. Feedback obtained from students during the pilot teaching contributed to shaping the Module’s final structure and content. The Module – an important interactive sustainability pedagogical tool – is now ready for use with students from different disciplines, thus contributing to progress towards the UN 2030 Agenda, particularly SDG 4, SDG 11, SDG 12, and SDG 13.Project “EUSTEPs: Enhancing Universities’ Sustainability Teaching and Practices through Ecological Footprint,” KA 203, Strategic Partnership in Higher Education 2019–2022, Agreement No. 2019-1-EL01-KA203-062941.info:eu-repo/semantics/publishedVersio

The Observation of Up-going Charged Particles Produced by High Energy Muons in Underground Detectors

An experimental study of the production of up-going charged particles in inelastic interactions of down-going underground muons is reported, using data obtained from the MACRO detector at the Gran Sasso Laboratory. In a sample of 12.2 10^6 single muons, corresponding to a detector livetime of 1.55 y, 243 events are observed having an up-going particle associated with a down-going muon. These events are analysed to determine the range and emission angle distributions of the up-going particle, corrected for detection and reconstruction efficiency. Measurements of the muon neutrino flux by underground detectors are often based on the observation of through-going and stopping muons produced in $\nu_\mu$ interactions in the rock below the detector. Up-going particles produced by an undetected down-going muon are a potential background source in these measurements. The implications of this background for neutrino studies using MACRO are discussed.Comment: 18 pages, 9 figures. Accepted by Astrop. Physic

Association of Maternal Perinatal SARS-CoV-2 Infection With Neonatal Outcomes During the COVID-19 Pandemic in Massachusetts

Importance: The incidence of mother-to-newborn SARS-CoV-2 transmission appears low and may be associated with biological and social factors. However, data are limited on the factors associated with neonatal clinical or viral testing outcomes. Objective: To ascertain the percentage of neonates who were born to mothers with positive SARS-CoV-2 test results during the birth hospitalization, the clinical and sociodemographic factors associated with neonatal test result positivity, and the clinical and virological outcomes for newborns during hospitalization and 30 days after discharge. Design, Setting, and Participants: This multicenter cohort study included 11 academic or community hospitals in Massachusetts and mother-neonate dyads whose delivery and discharge occurred between March 1, 2020, and July 31, 2020. Eligible dyads were identified at each participating hospital through local COVID-19 surveillance and infection control systems. Neonates were born to mothers with positive SARS-CoV-2 test results within 14 days before to 72 hours after delivery, and neonates were followed up for 30 days after birth hospital discharge. Exposures: Hypothesized maternal risk factors in neonatal test result positivity included maternal COVID-19 symptoms, vaginal delivery, rooming-in practice, Black race or Hispanic ethnicity, and zip code-derived social vulnerability index. Delivery indicated by worsening maternal COVID-19 symptoms was hypothesized to increase the risk of adverse neonatal health outcomes. Main Outcomes and Measures: Primary outcomes for neonates were (1) positive SARS-CoV-2 test results, (2) indicators of adverse health, and (3) clinical signs and viral testing. Test result positivity was defined as at least 1 positive result on a specimen obtained by nasopharyngeal swab using a polymerase chain reaction-based method. Clinical and testing data were obtained from electronic medical records of nonroutine health care visits within 30 days after hospital discharge. Results: The cohort included 255 neonates (mean [SD] gestational age at birth, 37.9 [2.6] weeks; 62 [24.3%] with low birth weight or preterm delivery) with 250 mothers (mean [SD] age, 30.4 [6.3] years; 121 [48.4%] were of Hispanic ethnicity). Of the 255 neonates who were born to mothers with SARS-CoV-2 infection, 225 (88.2%) were tested for SARS-CoV-2 and 5 (2.2%) had positive results during the birth hospitalization. High maternal social vulnerability was associated with higher likelihood of neonatal test result positivity (adjusted odds ratio, 4.95; 95% CI, 1.53-16.01; P = .008), adjusted for maternal COVID-19 symptoms, delivery mode, and rooming-in practice. Adverse outcomes during hospitalization were associated with preterm delivery indicated by worsening maternal COVID-19 symptoms. Of the 151 newborns with follow-up data, 28 had nonroutine clinical visits, 7 underwent SARS-CoV-2 testing, and 1 had a positive result. Conclusions and Relevance: The findings emphasize the importance of both biological and social factors in perinatal SARS-CoV-2 infection outcomes. Newborns exposed to SARS-CoV-2 were at risk for both direct and indirect adverse health outcomes, supporting efforts of ongoing surveillance of the virus and long-term follow-up

Instability of short arm of acrocentric chromosomes : Lesson from non-acrocentric satellited chromosomes. Report of 24 unrelated cases

Satellited non-acrocentric autosomal chromosomes (ps-qs-chromosomes) are the result of an interchange between sub- or telomeric regions of autosomes and the p arm of acrocentrics. The sequence homology at the rearrangement breakpoints appears to be, among others, the most frequent mechanism generating these variant chromosomes. The unbalanced carriers of this type of translocation may or may not display phenotypic abnormalities. With the aim to understand the causative mechanism, we revised all the ps-qs-chromosomes identified in five medical genetics laboratories, which used the same procedures for karyotype analysis, reporting 24 unrelated cases involving eight chromosomes. In conclusion, we observed three different scenarios: true translocation, benign variant and complex rearrangement. The detection of translocation partners is essential to evaluate possible euchromatic unbalances and to infer their effect on phenotype. Moreover, we emphasize the importance to perform both, molecular and conventional cytogenetics methods, to better understand the behavior of our genome