La comunicación académica y la visibilidad de las publicaciones universitarias

El objetivo principal de la universidad es la producción y transmisión de conocimiento. Las vías para esta transmisión han estado tradicionalmente acotadas a la cátedra universitaria y las publicaciones producidas por el cuerpo docente. Sin embargo, las nuevas formas de difusión de la información plantean un reto y este es un momento crucial para las editoriales y publicaciones universitarias.Tesi

Reduced proliferation of endothelial colony-forming cells in unprovoked venous thromboembolic disease as a consequence of endothelial dysfunction

Background Venous thromboembolic disease (VTD) is a public health problem. We recently reported that endothelial colony-forming cells (ECFCs) derived from endothelial cells (EC) (ECFC-ECs) from patients with VTD have a dysfunctional state. For this study, we proposed that a dysfunctional status of these cells generates a reduction of its proliferative ability, which is also associated with senescence and reactive oxygen species (ROS). Methods and results Human mononuclear cells (MNCs) were obtained from peripheral blood from 40 healthy human volunteers (controls) and 50 patients with VTD matched by age (20−50 years) and sex to obtain ECFCs. We assayed their proliferative ability with plasma of patients and controls and supernatants of cultures from ECFC-ECs, senescence-associated β-galactosidase (SA-β-gal), ROS, and expression of ephrin-B2/Eph-B4 receptor. Compared with cells from controls, cells from VTD patients showed an 8-fold increase of ECFCs that emerged 1 week earlier, reduced proliferation at long term (39%) and, in passages 4 and 10, a highly senescent rate (30±1.05% vs. 91.3±15.07%, respectively) with an increase of ROS and impaired expression of ephrin-B2/Eph-4 genes. Proliferation potential of cells from VTD patients was reduced in endothelial medium [1.4±0.22 doubling population (DP)], control plasma (1.18±0.31 DP), or plasma from VTD patients (1.65±0.27 DP). Conclusions As compared with controls, ECFC-ECs from individuals with VTD have higher oxidative stress, proliferation stress, cellular senescence, and low proliferative potential. These findings suggest that patients with a history of VTD are ECFC-ECs dysfunctional that could be associated to permanent risk for new thrombotic events

First observations on colony structure, behavior and vocal repertoire of the South American fur seal (Arctocephalus australis, Zimmermann 1783) in Peru

Trillmich F, Majluf P. First observations on colony structure, behavior and vocal repertoire of the South American fur seal (Arctocephalus australis, Zimmermann 1783) in Peru. Zeitschrift für Säugetierkunde. 1981;46:310-322

Distribution and abundance of sea lions (Otaria byronia) and fur seals (Arctocephalus australis) in Peru

Majluf P, Trillmich F. Distribution and abundance of sea lions (Otaria byronia) and fur seals (Arctocephalus australis) in Peru. Zeitschrift für Säugetierkunde. 1981;46:384-393

Reproductive ecology of female South American fur seals at Punta San Juan, Peru.

This thesis is not available on this repository until the author agrees to make it public. If you are the author of this thesis and would like to make your work openly available, please contact us: [email protected] Library can supply a digital copy for private research purposes; interested parties should submit the request form here: http://www.lib.cam.ac.uk/collections/departments/digital-content-unit/ordering-imagesPlease note that print copies of theses may be available for consultation in the Cambridge University Library's Manuscript reading room. Admission details are at http://www.lib.cam.ac.uk/collections/departments/manuscripts-university-archive

Attendance and diving behavior of South American fur seals during El Nino in 1983

Trillmich F, Kooyman GL, Majluf P, Sanchez-Grinan M. Attendance and diving behavior of South American fur seals during El Nino in 1983. In: Gentry RL, Kooyman GL, eds. Fur seals. Princeton, NJ: Princeton Univ. Pr.; 1986: 153-167

Evidence of a genetic bottleneck in an El Nino affected population of South American fur seals, Arctocephalus australis

Rosa de Oliveira L, Meyer D, Hoffman J, Majluf P, Morgante JS. Evidence of a genetic bottleneck in an El Nino affected population of South American fur seals, Arctocephalus australis. Journal of the Marine Biological Association of the United Kingdom. 2009;89(08):1717-1725

Testing Bergmann's rule and the Rosenzweig hypothesis with craniometric studies of the South American sea lion

We tested the validity of Bergmann's rule and Rosenzweig's hypothesis through an analysis of the geographical variation of the skull size of Otaria flavescens along the entire distribution range of the species (except Brazil). We quantified the sizes of 606 adult South American sea lion skulls measured in seven localities of Peru, Chile, Uruguay, Argentina, and the Falkland/Malvinas Islands. Geographical and environmental variables included latitude, longitude, and monthly minimum, maximum, and mean air and ocean temperatures. We also included information on fish landings as a proxy for productivity. Males showed a positive relationship between condylobasal length (CBL) and latitude, and between CBL and the six temperature variables. By contrast, females showed a negative relationship between CBL and the same variables. Finally, female skull size showed a significant and positive correlation with fish landings, while males did not show any relationship with this variable. The body size of males conformed to Bergmann's rule, with larger individuals found in southern localities of South America. Females followed the converse of Bergmann's rule at the intraspecific level, but showed a positive relationship with the proxy for productivity, thus supporting Rosenzweig's hypothesis. Differences in the factors that drive body size in females and males may be explained by their different life-history strategies. Our analyses demonstrate that latitude and temperature are not the only factors that explain spatial variation in body size: others such as food availability are also important for explaining the ecogeographical patterns found in O. flavescens.Fil: Sepúlveda, Maritza. Universidad de Valparaíso; ChileFil: Oliva, Doris. Universidad de Valparaíso; ChileFil: Duran, L. René. Universidad de Valparaíso; ChileFil: Urra, Alejandra. Universidad de Valparaíso; ChileFil: Pedraza, Susana Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico; ArgentinaFil: Majluf, Patricia. Universidad Peruana Cayetano Heredia; PerúFil: Prosser Goodall, Rae Natalie. Museo Acatushún de Aves y Mamíferos Marinos Australes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Austral de Investigaciones Científicas; ArgentinaFil: Crespo, Enrique Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico; Argentin