23,305 research outputs found
Reliability models applicable to space telescope solar array assembly system
A complex system may consist of a number of subsystems with several components in series, parallel, or combination of both series and parallel. In order to predict how well the system will perform, it is necessary to know the reliabilities of the subsystems and the reliability of the whole system. The objective of the present study is to develop mathematical models of the reliability which are applicable to complex systems. The models are determined by assuming k failures out of n components in a subsystem. By taking k = 1 and k = n, these models reduce to parallel and series models; hence, the models can be specialized to parallel, series combination systems. The models are developed by assuming the failure rates of the components as functions of time and as such, can be applied to processes with or without aging effects. The reliability models are further specialized to Space Telescope Solar Arrray (STSA) System. The STSA consists of 20 identical solar panel assemblies (SPA's). The reliabilities of the SPA's are determined by the reliabilities of solar cell strings, interconnects, and diodes. The estimates of the reliability of the system for one to five years are calculated by using the reliability estimates of solar cells and interconnects given n ESA documents. Aging effects in relation to breaks in interconnects are discussed
A uracil nitroso amine based colorimetric sensor for the detection of Cu²⁺ ions from aqueous environment and its practical applications
A simple uracil nitroso amine based colorimetric chemosensor (UNA-1) has been synthesized and screened for its cation recognition ability. Sensor UNA-1 exhibited a high sensitivity and selectivity towards Cu²⁺ ions in aqueous medium in the presence of a wide range of other competing cations (Ag⁺, Al³⁺, Ba²⁺+, Ca²⁺, Cd²⁺, Co²⁺, Cr³⁺, Cs⁺, Fe²⁺, Fe³⁺, Li⁺, Mg²⁺, Mn²⁺, Na⁺, Ni²⁺, Pb²⁺, Zn²⁺, Hg²⁺ and Sr²⁺). With Cu²⁺, the sensor UNA-1 gave a distinct color change from colorless to dark yellow by forming a complex of 1:1 stoichiometry. Furthermore, sensor UNA-1 was successfully utilized in the preparation of test strips and supported silica for the detection of Cu²⁺ ions from aqueous environment
Correlating features in the primordial spectra
Heavy fields coupled to the inflaton reduce the speed of sound in the
effective theory of the adiabatic mode each time the background inflationary
trajectory deviates from a geodesic. This can result in features in the
primordial spectra. We compute the corresponding bispectrum and show that if a
varying speed of sound induces features in the power spectrum, the change in
the bispectrum is given by a simple formula involving the change in the power
spectrum and its derivatives. In this manner, we provide a uniquely
discriminable signature of a varying sound speed for the adiabatic mode during
inflation that indicates the influence of heavy fields. We find that features
in the bispectrum peak in the equilateral limit and, in particular, in the
squeezed limit we find considerable enhancement entirely consistent with the
single field consistency relation. From the perspective of the underlying
effective theory, our results generalize to a wide variety of inflationary
models where features are sourced by the time variation of background
quantities. A positive detection of such correlated features would be
unambiguous proof of the inflaton's nature as a single light scalar degree of
freedom embedded in a theory that is UV completable.Comment: 5 pages, 1 figure; matches published versio
Exploring the Subaltern Voices: A Study of Community Radio Reporters (CRR\u27s) in Rural India
Despite India’s remarkable communication media revolution the rural subalterns remained uninformed, unheard and voiceless, who asks the question: Whose Media, Whose Voice? This created a space for community radio (CR) because it is of, for, and by the community. However, in spite of the alternative, counter-hegemonic, and participatory communication ethos, the contribution of CR’s and CRR’s lingered unexplored and unacknowledged. To bridge this gap, within the theoretical framework of alternative-media-theory this study has been undertaken. Based on case studies of India’s pioneer CR’s (Sangam Radio and Radio Bundelkhand) using media ethnography tools a qualitative inquiry was carried out. Findings suggest that CR’s can be seen as means of developing capabilities among the subalterns through equitable inclusion not merely as participants but as active producers, partners and managers. The dialectical, dynamic, non-hierarchical and citizen controlled journalism of CRR’s reflects antagonisms of reality and high level of community belongingness and responsibility that created fundamental distinctiveness-challenges to mainstream media. Finally, providing platform for expression enlarges the voices of the subalterns which will ultimately facilitate community dialogs and deliberations around local issues and helps to redefine their community identity in their own way and might lead to positive social change
Mass hierarchies and non-decoupling in multi-scalar field dynamics
In this work we study the effects of field space curvature on scalar field
perturbations around an arbitrary background field trajectory evolving in time.
Non-trivial imprints of the 'heavy' directions on the low energy dynamics arise
when the vacuum manifold of the potential does not coincide with the span of
geodesics defined by the sigma model metric of the full theory. When the
kinetic energy is small compared to the potential energy, the field traverses a
curve close to the vacuum manifold of the potential. The curvature of the path
followed by the fields can still have a profound influence on the perturbations
as modes parallel to the trajectory mix with those normal to it if the
trajectory turns sharply enough. We analyze the dynamical mixing between these
non-decoupled degrees of freedom and deduce its non-trivial contribution to the
low energy effective theory for the light modes. We also discuss the
consequences of this mixing for various scenarios where multiple scalar fields
play a vital role, such as inflation and low-energy compactifications of string
theory.Comment: 16 pages, 2 figures, typeset in PRD style. v2: Minor changes
throughout to emphasize that the analysis also applies to sharp and/or
prolonged turns. References adde
Could the Anti-Chaperone VER155008 Replace Temozolomide for Glioma Treatment
Cancer inducible molecular chaperone HSP90 is of great importance as an anticancer target. Proteomic analysis showed that inhibiting HSP90 by the geldanamycin derivative, 17-AAG elevated the expression of the co-chaperone Hsp70. In this study we used HSP90 selective inhibitor 17-AAG and HSP70/90 dual inhibitor, VER155008 (VER) in U87-MG glioma cells. miRNAs microarray technology was used to evaluate the efficacy of these inhibitory drugs compared with temozolomide (TMZ), used as a standard treatment for glioma. Microarrays data identified 154 differentially expressed miRNAs using stringent or unstringent parameters. 16 miRNAs were overlapped between treatments, 13 upregulated and one downregulated miRNA were overlapped between TMZ and VER. The miRNA target prediction software was used for these overlapped miRNAs and identified 6 of the 13 upregulated miRNAs target methyltransferase genes. The IC50, together with Akt and HSP70 and 90 protein level data favour VER and TMZ to 17-AAG, however due to the selectivity of VER to cancer cells as a potent antichaperon, it may be more favourable to the standard TMZ
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