15 research outputs found

    Enhanced Distributed File Replication Protocol for Efficient File Sharing in Wireless Mobile Ad-Hoc Networks.

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    File sharing applications in mobile unintended networks (MANETs) have attracted additional and additional attention in recent years. The potency of file querying suffers from the distinctive properties of such networks as well as node quality and restricted communication vary and resource. associate degree intuitive methodology to alleviate this drawback is to form file replicas within the network. However, despite the efforts on file replication, no analysis has targeted on the worldwide optimum duplicate creation with minimum average querying delay. Specifically, current file replication protocols in mobile unintended networks have 2 shortcomings. First, they lack a rule to portion restricted resources to completely different files so as to reduce the typical querying delay. Second, they merely contemplate storage as offered resources for replicas, however neglect the actual fact that the file holders’ frequency of meeting different nodes additionally plays a crucial role in deciding file availableness. Actually, a node that contains a higher meeting frequency with others provides higher availableness to its files. This becomes even additional evident in sparsely distributed MANETs, during which nodes meet disruptively. during this paper, we have a tendency to introduce a replacement conception of resource for file replication, that considers each node storage and meeting frequency. we have a tendency to on paper study the influence of resource allocation on the typical querying delay and derive a resource allocation rule to reduce the typical querying delay. we have a tendency to additional propose a distributed file replication protocol to appreciate the projected rule. intensive trace-driven experiments with synthesized traces and real traces show that our protocol are able to do shorter average querying delay at a lower value than current replication protocols

    Constraining the epoch of reionization with the variance statistic: simulations of the LOFAR case

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    Several experiments are underway to detect the cosmic redshifted 21-cm signal from neutral hydrogen from the Epoch of Reionization (EoR). Due to their very low signal-to-noise ratio, these observations aim for a statistical detection of the signal by measuring its power spectrum. We investigate the extraction of the variance of the signal as a first step towards detecting and constraining the global history of the EoR. Signal variance is the integral of the signal's power spectrum, and it is expected to be measured with a high significance. We demonstrate this through results from a simulation and parameter estimation pipeline developed for the Low Frequency Array (LOFAR)-EoR experiment. We show that LOFAR should be able to detect the EoR in 600 hours of integration using the variance statistic. Additionally, the redshift (zrz_r) and duration (Δz\Delta z) of reionization can be constrained assuming a parametrization. We use an EoR simulation of zr=7.68z_r = 7.68 and Δz=0.43\Delta z = 0.43 to test the pipeline. We are able to detect the simulated signal with a significance of 4 standard deviations and extract the EoR parameters as zr=7.720.18+0.37z_r = 7.72^{+0.37}_{-0.18} and Δz=0.530.23+0.12\Delta z = 0.53^{+0.12}_{-0.23} in 600 hours, assuming that systematic errors can be adequately controlled. We further show that the significance of detection and constraints on EoR parameters can be improved by measuring the cross-variance of the signal by cross-correlating consecutive redshift bins.Comment: 13 pages, 14 figures, Accepted for publication in MNRA

    Assessing Shoulder Dysfunction Following Neck Dissection for Treating Squamous Cell Carcinoma of the Oral Cavity

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    <p>Aim: The objective of this study is to evaluate the impact of neck dissection on shoulder dysfunction, encompassing pain and disability, over a six-month follow-up period in individuals who have undergone surgery for squamous cell carcinoma of the oral cavity. Objectives: This observational study was conducted to assess the evolution of the degree and extent of shoulder pain and shoulder disability during a six-month period following neck dissection. Materials and methods: All patients who had undergone neck dissection as part of their treatment for squamous cell carcinoma of the oral cavity and had provided written consent to participate in the study were subjected to an evaluation of shoulder dysfunction using the SPADI index. The SPADI questionnaire was administered, and corresponding scores were assigned to each patient based on their responses. Result: In summary, the manipulation of cranial nerve XI during neck dissection indeed leads to shoulder pain, decreased shoulder range of motion, reduced strength, and limitations in shoulder-related activities. Furthermore, the degree of manipulation of cranial nerve XI has a notable impact on these outcomes.</p><p> </p&gt

    Trouble-Free Multicomponent Method for Combinatorial Synthesis of 2‑Amino-4-phenyl-5‑<i>H</i>‑indeno[1,2‑<i>d</i>]pyrimidine-5-one and Their Screening against Cancer Cell Lines

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    The present study describes an alkaline water–ethanol mediated series of combinatorial synthesis of 2-amino-4-phenyl-5-<i>H</i>-indeno­[1,2<i>d</i>]­pyrimidine-5-one derivatives through sequential multicomponent reaction of 1,3indandione, aromatic aldehydes, and guanidine hydrochloride along with their anticancer evaluation. The effect of sequential addition of the components in the configuration of the desired product has been studied by UV–visible absorption spectroscopy. The synthetic method obeys most of the green chemistry principles in regard to high atom economy and greener, nontoxic, and noncarcinogenic solvent system (water–ethanol). The selected synthesized compounds have been screened against the human breast cancer cell line MCF7, human colon cancer cell line HT29, and normal viro monkey cell line, out of which 2-amino-4-(4-meth­oxy­phenyl)-5<i>H</i>-indeno­[1,2-<i>d</i>]­pyrimidin-5-one showed significant potency toward human breast cancer cell line (MCF7)
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