Schistosomus reflexus en un felino: reporte de caso

The case of a 5-year-old crossbred female cat in her first gestation was presented for consultation. The cat had a stillborn present in the birth canal, which was extracted manually. A second puppy is expelled alive but was euthanized because of her clinical infeasibility. The two puppies presented a malformation in the abdominal region with exposure of some viscera, considered as Schistosomus reflexus syndrome. The radiological and necropsy diagnostic evaluation of the second puppy was performed, finding a closure defect of the abdominal midline with viscera exposure (small intestine, liver, right kidney and spleen among others). The radiological evaluation showed the eventration of abdominal organs without clear differentiation between them, kyphosis in the thoracolumbar segment, lordosis in the lumbar portion and oligodactyly in the right posterior limb.Se presenta el caso de una hembra felina de raza mestiza de 5 años en su primer parto llevada a consulta. La gata tenía un mortinato presente en el canal de parto el cual se extrae manualmente. Un segundo cachorro es expulsado vivo, pero por su la inviabilidad clínica se procedió a la eutanasia. Las dos crías presentaron una malformación en la región abdominal con exposición de algunas vísceras, considerada como el síndrome de Schistosomus reflexus. Se realizó la evaluación diagnóstica radiológica y por necropsia del segundo cachorro encontrando un defecto de cierre de la línea media abdominal con exposición de vísceras (intestino delgado, hígado, riñón derecho y bazo entre otros). En la evaluación radiológica se evidenció eventración de órganos abdominales sin diferenciación clara entre ellos, cifosis en el segmento toracolumbar, lordosis en la porción lumbar y oligodactilia en el miembro posterior derecho

Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS-COV-2/COVID-19 en establecimientos de atención de la salud Recomendaciones basadas en consenso de expertos e informadas en la evidencia

The “Asociación Colombiana de Infectología” (ACIN) and the “Instituto de Evaluación de Nuevas Tecnologías de la Salud” (IETS) created a task force to develop recommendations for Covid 19 health care diagnosis, management and treatment informed, and based, on evidence. Theses reccomendations are addressed to the health personnel on the Colombian context of health services. © 2020 Asociacion Colombiana de Infectologia. All rights reserved

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

To investigate large structural clonal mosaicism of chromosome X, we analysed the SNP microarray intensity data of 38,303 women from cancer genome-wide association studies (20,878 cases and 17,425 controls) and detected 124 mosaic X events42Mb in 97 (0.25%) women. Here we show rates for X-chromosome mosaicism are four times higher than mean autosomal rates; X mosaic events more often include the entire chromosome and participants with X events more likely harbour autosomal mosaic events. X mosaicism frequency increases with age (0.11% in 50-year olds; 0.45% in 75-year olds), as reported for Y and autosomes. Methylation array analyses of 33 women with X mosaicism indicate events preferentially involve the inactive X chromosome. Our results provide further evidence that the sex chromosomes undergo mosaic events more frequently than autosomes, which could have implications for understanding the underlying mechanisms of mosaic events and their possible contribution to risk for chronic diseases

Evidence for a latitudinal diversity gradient in liverworts and hornworts

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