AWARENESS AND USE OF SOCIAL MEDIA AMONG PG STUDENTS OF CCS HARYANA AGRICULTURAL UNIVERSITY, HISAR

T The present paper reflects the status of awareness and use of social media tools among PG students of CCS Haryana Agricultural University, Hisar. For collecting data questionnaire technique was adopted wherein 60 questionnaire were distributed among PG students. The results shows that 100 percent respondants were aware and using social media tools in the University. Facebook, Watsup and Youtube were the most used social media tools; preffered device for using social media was smartphone; prefered place was home or hostel; and main difficulties in using social media tools were academic pressure & restriction of using social media in computer labs of University

Web Citations and Decay of URLs: A Case Study of Indian Journal of Agricultural Library and Information Services.

The present study is conducted to identify the prevailing citation trends, durability of web citations or URLs, decay and half-life of URLs by analyzing articles’ citations of Indian Journal of Agricultural Library and Information Services published during 2012 -2016. A total of 980 citations were reported in 94 articles out of which 33.16 percent were having web citations. Of web citations, 62.15 percent of URLs were accessible at the time of testing and the remaining 37.85 percent of URLs were not accessible. HTTP error message 404 “page not found’’ was the irresistible error message appeared and represented 51.22 percent of all HTTP error messages. Average half-life of URLs was estimated to be 4.62 years. There was no association found between path depth and decay of URLs. Articles accessed from domain .org, .net and .co/.com were found more alive than other domains

Knowledge Sharing Idiosyncrasies of Research Scholars at CCS Haryana Agricultural University, Hisar, India

The main aim of the present study is to investigate the knowledge sharing behaviour of research scholars at Chaudhary Charan Singh Haryana Agricultural University (CCS HAU), Hisar, India. To understand and reveal the knowledge sharing idiosyncrasies of research scholars, various factors have been covered such as knowledge sharing definition, knowledge sharing attitude, communication channels preferred for knowledge sharing, barriers of knowledge sharing, knowledge sharing motivators, and other factors related to knowledge sharing in an academic institution. For the present study, survey method was adopted with the aid of online structured questionnaire for the purpose of data collection. Total 125 research scholars were approached electronically and shared questionnaires through WhatsApp groups and personal e-mails. Out of total 125, 114 valid questionnaires were collected and considered for final analysis, which representing the response rate of about 91.2 per cent. The findings reveals that about 66% of the respondents were in the opinion that sharing knowledge with peers shall benefit all and majority of the respondents possessed a positive attitude towards knowledge sharing and were aware of its importance in their learning process. The face-to-face interaction for sharing knowledge among the respondents is the most preferred communication channel for majority of the respondents (81.58%); however, some major barriers of knowledge sharing among the research scholars have also been noticed. In order to overcome these barriers, the researchers suggest that academic institutions may foster cordial relationship among the research scholars by providing sufficient interaction opportunities. In the end, practical implication of this study has also been discussed

Sustainability through Agroforestry in Himalayas: An overview

This record was migrated from the OpenDepot repository service in June, 2017 before shutting down

Increasing secondary resistance to fluoroquinolones amongst Helicobacter pylori in Western Australia

Background: The Australian Therapeutic Guidelines does not endorse culture and susceptibility testing prior to salvage therapy for Helicobacter pylorieradication. We wished to determine whether this remains appropriate. Aim: To determine the sensitivity (as minimum inhibitory concentrations, MIC) of H pylorito a range of antibiotics used in salvage therapy over time. Methods: From 2012 to 2017, gastric or duodenal biopsy samples were obtained from 154 patients receiving H pylorieradication therapy. MIC for amoxicillin, clarithromycin, tetracycline, metronidazole, rifampicin and levofloxacinwere measured using standard laboratory techniques. Results: A significant increase from zero to 28% in secondary resistance to levofloxacin amongst H. pyloriin Western Australia was noted over the study period. No corresponding trend was seen with the other antibiotics. Conclusions: These findings suggest that selective use of culture and susceptibility testing may be warranted prior to initiating salvage therapy with levofloxacin

Preserving Buyer-Privacy in Decentralized Supply Chain Marketplaces

Technology is being used increasingly for lowering the trust barrier in domains where collaboration and cooperation are necessary, but reliability and efficiency are critical due to high stakes. An example is an industrial marketplace where many suppliers must participate in production while ensuring reliable outcomes; hence, partnerships must be pursued with care. Online marketplaces like Xometry facilitate partnership formation by vetting suppliers and mediating the marketplace. However, such an approach requires that all trust be vested in the middleman. This centralizes control, making the system vulnerable to being biased towards specific providers. The use of blockchains is now being explored to bridge the trust gap needed to support decentralizing marketplaces, allowing suppliers and customers to interact more directly by using the information on the blockchain. A typical scenario is the need to preserve privacy in certain interactions initiated by the buyer (e.g., protecting a buyer’s intellectual property during outsourcing negotiations). In this work, we initiate the formal study of matching between suppliers and buyers when buyer-privacy is required for some marketplace interactions and make the following contributions. First, we devise a formal security definition for private interactive matching in the Universally Composable (UC) Model that captures the privacy and correctness properties expected in specific supply chain marketplace interactions. Second, we provide a lean protocol based on any programmable blockchain, anonymous group signatures, and public-key encryption. Finally, we implement the protocol by instantiating some of the blockchain logic by extending the BigChainDB blockchain platform

Utility and limitations of hepascore and transient elastography to detect advanced hepatic fibrosis in HFE hemochromatosis

Aspartate aminotransferase-to-platelet ratio index (APRI) and Fibrosis-4 Index (Fib4) have been validated against liver biopsy for detecting advanced hepatic fibrosis in HFE hemochromatosis. We determined the diagnostic utility for advanced hepatic fibrosis of Hepascore and transient elastography compared with APRI and Fib4 in 134 newly diagnosed HFE hemochromatosis subjects with serum ferritin levels \u3e 300 µg/L using area under the receiver operator characteristic curve (AUROC) analysis and APRI- ( \u3e 0.44) or Fib4- ( \u3e 1.1) cut-offs for AHF, or a combination of both. Compared with APRI, Hepascore demonstrated an AUROC for advanced fibrosis of 0.69 (95% CI 0.56–0.83; sensitivity = 69%, specificity = 65%; P = 0.01) at a cut-off of 0.22. Using a combination of APRI and Fib4, the AUROC for Hepascore for advanced fibrosis was 0.70 (95% CI 0.54–0.86, P = 0.02). Hepascore was not diagnostic for detection of advanced fibrosis using the Fib4 cut-off. Elastography was not diagnostic using either APRI or Fib4 cut-offs. Hepascore and elastography detected significantly fewer true positive or true negative cases of advanced fibrosis compared with APRI and Fib4, except in subjects with serum ferritin levels \u3e 1000 µg/L. In comparison with APRI or Fib4, Hepascore or elastography may underdiagnose advanced fibrosis in HFE Hemochromatosis, except in individuals with serum ferritin levels \u3e 1000 µg/L

LncRNA VEAL2 regulates PRKCB2 to modulate endothelial permeability in diabetic retinopathy

Long non‐coding RNAs (lncRNAs) are emerging as key regulators of endothelial cell function. Here, we investigated the role of a novel vascular endothelial‐associated lncRNA (VEAL2) in regulating endothelial permeability. Precise editing of veal2 loci in zebrafish (veal2 (gib005Δ8/+)) induced cranial hemorrhage. In vitro and in vivo studies revealed that veal2 competes with diacylglycerol for interaction with protein kinase C beta‐b (Prkcbb) and regulates its kinase activity. Using PRKCB2 as bait, we identified functional ortholog of veal2 in humans from HUVECs and named it as VEAL2. Overexpression and knockdown of VEAL2 affected tubulogenesis and permeability in HUVECs. VEAL2 was differentially expressed in choroid tissue in eye and blood from patients with diabetic retinopathy, a disease where PRKCB2 is known to be hyperactivated. Further, VEAL2 could rescue the effects of PRKCB2‐mediated turnover of endothelial junctional proteins thus reducing hyperpermeability in hyperglycemic HUVEC model of diabetic retinopathy. Based on evidence from zebrafish and hyperglycemic HUVEC models and diabetic retinopathy patients, we report a hitherto unknown VEAL2 lncRNA‐mediated regulation of PRKCB2, for modulating junctional dynamics and maintenance of endothelial permeability

Global burden of atherosclerotic cardiovascular disease in people with hepatitis C virus infection: a systematic review, meta-analysis, and modelling study

Background: More than 70 million people worldwide are estimated to have hepatitis C virus (HCV) infection. Emerging evidence indicates an association between HCV and atherosclerotic cardiovascular disease. We aimed to determine the association between HCV and cardiovascular disease, and estimate the national, regional, and global burden of cardiovascular disease attributable to HCV. Methods: For this systematic review and meta-analysis, we searched MEDLINE, Embase, Ovid Global Health, and Web of Science databases from inception to May 9, 2018, without language restrictions, for longitudinal studies that evaluated the risk ratio (RR) of cardiovascular disease in people with HCV compared with those without HCV. Two investigators independently reviewed and extracted data from published reports. The main outcome was cardiovascular disease, defined as hospital admission with, or mortality from, acute myocardial infarction or stroke. We calculated the pooled RR of cardiovascular disease associated with HCV using a random-effects model. Additionally, we calculated the population attributable fraction and disability-adjusted life-years (DALYs) from HCV-associated cardiovascular disease at the national, regional, and global level. We also used age-stratified and sex-stratified HCV prevalence estimates and cardiovascular DALYs for 100 countries to estimate country-level burden associated with HCV. This study is registered with PROSPERO, number CRD42018091857. Findings: Our search identified 16 639 records, of which 36 studies were included for analysis, including 341 739 people with HCV. The pooled RR for cardiovascular disease was 1·28 (95% CI 1·18–1·39). Globally, 1·5 million (95% CI 0·9–2·1) DALYs per year were lost due to HCV-associated cardiovascular disease. Low-income and middle-income countries had the highest disease burden with south Asian, eastern European, north African, and Middle Eastern regions accounting for two-thirds of all HCV-associated cardiovascular DALYs. Interpretation: HCV infection is associated with an increased risk of cardiovascular disease. The global burden of cardiovascular disease associated with HCV infection was responsible for 1·5 million DALYs, with the highest burden in low-income and middle-income countries

Web Citations and Decay of URLs: A Case Study of Indian Journal of Agricultural Library and Information Services.

The present study is conducted to identify the prevailing citation trends, durability of web citations or URLs, decay and half-life of URLs by analyzing articles’ citations of Indian Journal of Agricultural Library and Information Services published during 2012 -2016. A total of 980 citations were reported in 94 articles out of which 33.16 percent were having web citations. Of web citations, 62.15 percent of URLs were accessible at the time of testing and the remaining 37.85 percent of URLs were not accessible. HTTP error message 404 “page not found’’ was the irresistible error message appeared and represented 51.22 percent of all HTTP error messages. Average half-life of URLs was estimated to be 4.62 years. There was no association found between path depth and decay of URLs. Articles accessed from domain .org, .net and .co/.com were found more alive than other domains