Mutualism supports biodiversity when the direct competition is weak

A key question of theoretical ecology is which properties of ecosystems favour their stability and help maintaining biodiversity. This qu estion recently reconsid- ered mutualistic systems, generating intense controversy about the role of mutu- alistic interactions and their network architecture. Here we show analytically and verify with simulations that reducing the effective intersp ecific competition and the propagation of perturbations positively influences struct ural stability against envi- ronmental perturbations, enhancing persistence. Notewor thy, mutualism reduces the effective interspecific competition only when the direct interspecific competition is weaker than a critical value. This critical competition i s in almost all cases larger in pollinator networks than in random networks with the same connectance. Highly connected mutualistic networks reduce the propagation of e nvironmental perturba- tions, a mechanism reminiscent of MacArthur’s proposal tha t ecosystem complexity enhances stability. Our analytic framework rationalizes p revious contradictory re- sults, and it gives valuable insight on the complex relation ship between mutualism and biodiversity

Cosmic acceleration: Inhomogeneity versus vacuum energy

In this essay, I present an alternative explanation for the cosmic acceleration which appears as a consequence of recent high redshift Supernova data. In the usual interpretation, this cosmic acceleration is explained by the presence of a positive cosmological constant or vacuum energy, in the background of Friedmann models. Instead, I will consider a Local Rotational Symmetric (LRS) inhomogeneous spacetime, with a barotropic equation of state for the cosmic matter. Within this framework the kinematical acceleration of the cosmic fluid or, equivalently, the inhomogeneity of matter, is just the responsible of the SNe Ia measured cosmic acceleration. Although in our model the Cosmological Principle is relaxed, it maintains local isotropy about our worldline in agreement with the CBR experiments.Comment: LATEX, 7 pags, no figs, Honorable Mention in the 1999 Essay Competition of the Gravity Research Foundatio

Moduli Spaces and Formal Operads

Let overline{M}_{g,n} be the moduli space of stable algebraic curves of genus g with n marked points. With the operations which relate the different moduli spaces identifying marked points, the family (overline{M}_{g,n})_{g,n} is a modular operad of projective smooth Deligne-Mumford stacks, overline{M}. In this paper we prove that the modular operad of singular chains C_*(overline{M};Q) is formal; so it is weakly equivalent to the modular operad of its homology H_*(overline{M};Q). As a consequence, the "up to homotopy" algebras of these two operads are the same. To obtain this result we prove a formality theorem for operads analogous to Deligne-Griffiths-Morgan-Sullivan formality theorem, the existence of minimal models of modular operads, and a characterization of formality for operads which shows that formality is independent of the ground field.Comment: 36 pages (v3: some typographical corrections

Fragmentation and the digital city: An analysis of Vicente Luis Mora's circular 07. Las afueras

This essay juxtaposes three recent publications, Vicente Luis Mora's Circular 07. Las afueras (2007-), Kenneth Goldsmith's Capital: New York, Capital of the 20th Century (2015), and Jorge Carrión's Barcelona. Libro de los pasajes (2016), in order to explore how contemporary digital technologies construct and fragment urban experience on a global scale. Despite their different political intentions, these three works share a common aesthetic of appropriation, unoriginal quotation, and fragmentation, as they are also all modelled after Walter Benjamin's Arcades Project. Just like Benjamin did with Paris, each of these works focuses on a particular Western city-Madrid, New York, and Barcelona-now being proposed as paradigmatic representations of urban experience, which is meant to mimic digital media's modularity and disintegration. Goldsmith's use of appropriation is read as a blank endorsement of digital mediation of everyday life, which sits in opposition to Carrión's and Mora's political projects. Circular 07 and Barcelona mix unoriginal writing techniques, like Goldsmith's conceptual writing, with other experimental methods to warn readers against apolitical adoption of digital technologies. Fragmentation is still proposed as the most important aesthetic form of twenty-first century writing, but these two Spanish works strive for its contextualization as a complex mechanism structured around reader/writer subjectivity. Finally, this essay ponders how to consider new reader/ writer subjectivities within the larger context of global cities in late capitalism

The Influence of Blockholders on R&D Investments Intensity: Evidence From Spain

Using data from 3,638 Spanish firms between 1996 and 2000, this article studies the relationship between the presence of large shareholders in the ownership structure of firms and R&D investment. Consistent with our theoretical contention, our results indicate that the impact of large shareholders on the R&D investment is (1) negative when blockholders are banks, (2) positive when blockholders are non-financial corporations, and (3) null when blockholders are individuals. In addition, we find a systematic negative relationship between the number of blockholders and R&D investment. Finally, we extend our study by analyzing the influence that the combined effect between blockholder type and R&D investment has on the firm’s economic performance. Results of this work provide relevant implications for policy makers and academic research.

Stars and brown dwarfs in the sigma Orionis cluster. III. OSIRIS/GTC low-resolution spectroscopy of variable sources

Context. Although many studies have been performed so far, there are still dozens of low-mass stars and brown dwarfs in the young sigma Orionis open cluster without detailed spectroscopic characterisation. Aims. We look for unknown strong accretors and disc hosts that were undetected in previous surveys. Methods. We collected low-resolution spectroscopy (R ~ 700) of ten low-mass stars and brown dwarfs in sigma Orionis with OSIRIS at the Gran Telescopio Canarias under very poor weather conditions. These objects display variability in the optical, infrared, Halpha, and/or X-rays on time scales of hours to years. We complemented our spectra with optical and near-/mid-infrared photometry. Results. For seven targets, we detected lithium in absorption, identified Halpha, the calcium doublet, and forbidden lines in emission, and/or determined spectral types for the first time. We characterise in detail a faint, T Tauri-like brown dwarf with an 18 h-period variability in the optical and a large Halpha equivalent width of -125+/-15 AA, as well as two M1-type, X-ray-flaring, low-mass stars, one with a warm disc and forbidden emission lines, the other with a previously unknown cold disc with a large inner hole. Conclusions. New unrevealed strong accretors and disc hosts, even below the substellar limit, await discovery among the list of known sigma Orionis stars and brown dwarfs that are variable in the optical and have no detailed spectroscopic characterisation yet.Comment: A&A, in press (accepted for publication in section 14. Catalogs and data of Astronomy and Astrophysics

Variability of voriconazole plasma levels measured by new high-performance liquid chromatography and bioassay methods, [and] Voriconazole therapeutic drug monitoring in patients with invasive mycoses improves efficacy and safety outcomes

Rapport de synthèse1. Partie de laboratoireCette première étude décrit le développement et la validation, selon les standards internationaux, de deux techniques de mesure des concentrations sanguines de voriconazole, un nouvel agent antifongique à large spectre: 1) la chromatographic en phase liquide à haute pression et 2) le bio-essai utilisant une souche mutante de Candida hypersensible au voriconazole. Ce travail a aussi permis de mettre en évidence une importante et imprévisible variabilité inter- et intra-individuelle des concentrations sanguines de voriconazole malgré l'utilisation des doses recommandées par le fabriquant. Ce travail a été publié dans un journal avec "peer-review": "Variability of voriconazole plasma levels measured by new high- performance liquid chromatography and bioassay methods" by A. Pascual, V. Nieth, T. Calandra, J. Bille, S. Bolay, L.A. Decosterd, T. Buclin, P.A. Majcherczyk, D. Sanglard, 0. Marchetti. Antimicrobial Agents Chemotherapy, 2007; 51:137-432. Partie CliniqueCette deuxième étude a évalué de façon prospective l'impact clinique des concentrations sanguines de voriconazole sur l'efficacité et sécurité thérapeutique chez des patients atteints d'infections fongiques. Des concentrations sanguines élevées étaient significativement associés à la survenue d'une toxicité neurologique (encéphalopathie avec confusion, hallucinations et myoclonies) et des concentrations sanguines basses à une réponse insuffisante au traitement antifongique (persistance ou progression des signes cliniques et radiologiques de l'infection). Dans la majorité des cas, un ajustement de la dose de voriconazole, sur la base des concentrations mesurées, a abouti à une récupération neurologique complète ou à une résolution de l'infection, respectivement. Ce travail a été publié dans un journal avec "peer-review": " Voriconazole Therapeutic Drug Monitoring in Patients with Invasive Mycoses Improves Efficacy and Safety Outcomes" by A. Pascual, T. Calandra, S. Bolay, T. Buclin, J. Bille, and O. Marchetti. Clinical Infectious Diseases, 2008 January 15; 46(2): 201-11.Ces deux études, financées de façon conjointe par un "grant" international de la Société suisse d'infectiologie et la Société internationale de maladies infectieuses et par la Fondation pour le progrès en microbiologie médicale et maladies infectieuses (FAMMID, Lausanne), ont été réalisées au sein du Service des Maladies Infectieuses, Département de Médecine, au CHUV, en étroite collaboration avec la Division de Pharmacologie Clinique, Département de Médecine, au CHUV et l'Institut de Microbiologie du CHUV et de l'Université de Lausanne

Numerical treatment of the light propagation problem in the post-Newtonian formalism

The geometry of a light wavefront, evolving from a initial flat wavefront in the 3-space associated with a post-Newtonian relativistic spacetime, is studied numerically by means of the ray tracing method. For a discretization of the bidimensional light wavefront, a surface fitting technique is used to determine the curvature of this surface. The relationship between the intrinsic curvature of the wavefront and the change of the arrival time at different points on the Earth is also numerically discussed.Comment: 7 pages, 1 fig., Talk given by JFPS in Sept, 10, 2009, to be published in JPCS as Proceedings of Spanish Relativity Meeting-ERE 200