5,807 research outputs found
Anomalous Thermoluminescent Kinetics of Irradiated Alkali Halides
Anomalous thermoluminescent kinetics of irradiated alkali halide
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The effect of elevated hydrostatic pressure on the spectral absorption of deep-sea fish visual pigments
The effect of hydrostatic pressure (0.1-54 MPa, equivalent to pressures experienced by fish from the ocean's surface to depths of ca. 5400 m) on visual pigment absorption spectra was investigated for rod visual pigments extracted from the retinae of 12 species of deep-sea fish of diverse phylogeny and habitat. The wavelength of peak absorption (λmax) was shifted to longer wavelengths by an average of 1.35 nm at 40 MPa (a pressure approximately equivalent to average ocean depth) relative to measurements made at one atmosphere (ca. 0.1 MPa), but with little evidence of a change in absorbance at the λmax. We conclude that previousλ max measurements of deep-sea fish visual pigments, made at a pressure close to 0.1 MPa, provide a good indication ofλ max values at higher pressures when considering the ecology of vision in the deep-sea. Although not affecting the spectral sensitivity of the animal to any important degree, the observed shift inλ max may be of interest in the context of understanding opsin-chromophore interaction and spectral tuning of visual pigments
An Energy-conscious Transport Protocol for Multi-hop Wireless Networks
We present a transport protocol whose goal is to reduce power consumption without compromising delivery requirements of applications. To meet its goal of energy efficiency, our transport protocol (1) contains mechanisms to balance end-to-end vs. local retransmissions; (2) minimizes acknowledgment traffic using receiver regulated rate-based flow control combined with selected acknowledgements and in-network caching of packets; and (3) aggressively seeks to avoid any congestion-based packet loss. Within a recently developed ultra low-power multi-hop wireless network system, extensive simulations and experimental results demonstrate that our transport protocol meets its goal of preserving the energy efficiency of the underlying network.Defense Advanced Research Projects Agency (NBCHC050053
The Bayesian Decision Tree Technique with a Sweeping Strategy
The uncertainty of classification outcomes is of crucial importance for many
safety critical applications including, for example, medical diagnostics. In
such applications the uncertainty of classification can be reliably estimated
within a Bayesian model averaging technique that allows the use of prior
information. Decision Tree (DT) classification models used within such a
technique gives experts additional information by making this classification
scheme observable. The use of the Markov Chain Monte Carlo (MCMC) methodology
of stochastic sampling makes the Bayesian DT technique feasible to perform.
However, in practice, the MCMC technique may become stuck in a particular DT
which is far away from a region with a maximal posterior. Sampling such DTs
causes bias in the posterior estimates, and as a result the evaluation of
classification uncertainty may be incorrect. In a particular case, the negative
effect of such sampling may be reduced by giving additional prior information
on the shape of DTs. In this paper we describe a new approach based on sweeping
the DTs without additional priors on the favorite shape of DTs. The
performances of Bayesian DT techniques with the standard and sweeping
strategies are compared on a synthetic data as well as on real datasets.
Quantitatively evaluating the uncertainty in terms of entropy of class
posterior probabilities, we found that the sweeping strategy is superior to the
standard strategy
Conventional versus highly cross-linked polyethylene in primary total knee replacement : a comparison of revision rates using data from the National Joint Registry for England, Wales, and Northern Ireland
There is evidence to support the use of highly cross-linked polyethylene (HXLPE) in patients undergoing total hip arthroplasty. However, the benefits for those undergoing total knee arthroplasty are uncertain, with conflicting reports based on previous cohort analyses. The purpose of the present study was to compare the revision rates following primary total knee arthroplasty with use of HXLPE as compared with conventional polyethylene (CPE) using data from the National Joint Registry (NJR) for England, Wales and Northern Ireland. We performed a retrospective analysis of primary total knee arthroplasties recorded in the NJR from 2003 to 2014. Cobalt-chromium (CoCr)-CPE and CoCr-HXLPE bearing surfaces were compared using all-cause revision, aseptic revision, and septic revision as end points. Survival analyses were conducted using rates per 100 years observed, Kaplan-Meier survival estimates, and Cox regression hazard ratios (HRs) adjusted for age, sex, American Society of Anesthesiologists (ASA) classification, body mass index (BMI), lead surgeon grade, and implant constraint. Secondary analyses compared the most commonly used HXLPEs (Zimmer Prolong, DePuy XLK, and Stryker X3) against CPE for the 3 most common total knee arthroplasty systems (NexGen, PFC Sigma, and Triathlon). In the present study of 550,658 total knee arthroplasties, the unadjusted aseptic revision rates were significantly lower following procedures performed with CPE (n = 513,744) as compared with those performed with HXLPE total knee replacements (n = 36,914) (0.29 [95% confidence interval (CI), 0.28 to 0.30] compared to 0.38 [95% CI, 0.35 to 0.42], p 35 kg/m, the "second-generation" Stryker X3 HXLPE demonstrated significantly better survival than its respective CPE, with CPE having an HR of 2.6 (95% CI, 1.2 to 5.9) (p = 0.02). Alternative bearings are marketed as having improved wear properties over traditional CoCr-CPE. This registry-based analysis demonstrated no overall survival benefit of HXLPE after a maximum duration of follow-up of 12 years. Because of their increased cost, the routine use of HXLPE bearings may not be justified. However, they may have a role in specific "higher demand" groups such as patients 35 kg/m. Therapeutic Level III. See Instructions for Authors for a complete list of levels of evidence
Planck Observations of M33
We have performed a comprehensive investigation of the global integrated flux
density of M33 from radio to ultraviolet wavelengths, finding that the data
between 100 GHz and 3 THz are accurately described by a single modified
blackbody curve with a dust temperature of = 21.670.30 K
and an effective dust emissivity index of = 1.350.10,
with no indication of an excess of emission at millimeter/sub-millimeter
wavelengths. However, sub-dividing M33 into three radial annuli, we found that
the global emission curve is highly degenerate with the constituent curves
representing the sub-regions of M33. We also found gradients in
and across the disk of M33, with both
quantities decreasing with increasing radius. Comparing the M33 dust emissivity
with that of other Local Group members, we find that M33 resembles the
Magellanic Clouds rather than the larger galaxies, i.e., the Milky Way and M31.
In the Local Group sample, we find a clear correlation between global dust
emissivity and metallicity, with dust emissivity increasing with metallicity. A
major aspect of this analysis is the investigation into the impact of
fluctuations in the Cosmic Microwave Background (CMB) on the integrated flux
density spectrum of M33. We found that failing to account for these CMB
fluctuations would result in a significant over-estimate of
by 5 K and an under-estimate of by 0.4.Comment: Accepted for publication in MNRA
Violation of the Cauchy-Schwarz inequality with matter waves
The Cauchy-Schwarz (CS) inequality -- one of the most widely used and
important inequalities in mathematics -- can be formulated as an upper bound to
the strength of correlations between classically fluctuating quantities.
Quantum mechanical correlations can, however, exceed classical bounds.Here we
realize four-wave mixing of atomic matter waves using colliding Bose-Einstein
condensates, and demonstrate the violation of a multimode CS inequality for
atom number correlations in opposite zones of the collision halo. The
correlated atoms have large spatial separations and therefore open new
opportunities for extending fundamental quantum-nonlocality tests to ensembles
of massive particles.Comment: Final published version (with minor changes). 5 pages, 3 figures,
plus Supplementary Materia
Semantic Transformation of Web Services
Web services have become the predominant paradigm for the development of distributed software systems. Web services provide the means to modularize software in a way that functionality can be described, discovered and deployed in a platform independent manner over a network (e.g., intranets, extranets and the Internet). The representation of web services by current industrial practice is predominantly syntactic in nature lacking the fundamental semantic underpinnings required to fulfill the goals of the emerging Semantic Web. This paper proposes a framework aimed at (1) modeling the semantics of syntactically defined web services through a process of interpretation, (2) scop-ing the derived concepts within domain ontologies, and (3) harmonizing the semantic web services with the domain ontologies. The framework was vali-dated through its application to web services developed for a large financial system. The worked example presented in this paper is extracted from the se-mantic modeling of these financial web services
Energetics of mixing for the filling box and the emptying-filling box
The mixing efficiency of a plume in a filling box and an emptying-filling box
is calculated for both transient and steady states. The mixing efficiency of a
plume in a filling box in an asymptotic steady state is 1/2, independent of the
details of this state or how the plume is modelled. The mixing efficiency of a
plume in an emptying-filling box in steady state is 1 - xi, where xi = h/H, the
depth of the ambient layer h non-dimensionalised by the height of the box H. A
deeper mixed layer therefore corresponds to a higher mixing efficiency
Participants' uptake of clinical trial results: a randomised experiment
BJC OPENInternational audienceBACKGROUND: Participants are showing great interest these days in obtaining the results of clinical trials. The aim of this study was to assess patients' uptake and understanding of the results of the trial in which they have participated and the impact of a letter offering patients the possibility of consulting the trial results on a specific website. METHODS: Breast cancer patients participating in a trial on the efficacy of Trastuzumab were randomly subdivided into an Internet group (who received the letter of invitation) and a control group (who did not receive it). Among 115 HER2-positive women from 21 centres, 107 (93%) answered a self-administered questionnaire. RESULTS: Most of the patients in both groups had access to the Internet (72.0%). The majority (97.2%) stated that receiving information about the trial results would be useful, and the oncologist was the most frequently preferred information provider. The Internet group's declared uptake of the trial results was only slightly higher (47.1% vs 33.9%; P=0.166); however, they understood the results significantly more accurately (18.8% vs 5.6%; P=0.039). INTERPRETATION: Although Internet was not the respondents' preferred source of information, the possibility of using this source slightly increased the uptake and understanding of the results
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