Pullback attractors for a singularly nonautonomous plate equation

We consider the family of singularly nonautonomous plate equation with structural damping $$u_{tt} + a(t,x)u_{t} + (- \Delta) u_{t} + (-\Delta)^{2} u + \lambda u = f(u),$$ in a bounded domain $\Omega \subset \R^n$, with Navier boundary conditions. When the nonlinearity $f$ is dissipative we show that this problem is globally well posed in $H^2_0(\Omega) \times L^2(\Omega)$ and has a family of pullback attractors which is upper-semicontinuous under small perturbations of the damping $a$

Digital tourism marketing: Case study of the campaign Can’t Skip Portugal

The theme of this study is the analysis of the advertising campaign "Can’t Skip Portugal" launched in 2017 by Tourism of Portugal, which the main objective was to show all the regions of the country, covering not only the most known areas but also to promote other areas of the country, showcasing Portugal as a potential destination for tourists. The objective of the study is to understand how this kind of Digital Marketing can be sufficiently appealing and arouse in-terest in the viewers. To reach the proposed objective, a qualitative research of descriptive type was carried out. Throughout this study it was possible to have a better understanding of the benefits of Digital Marketing. It could be con-cluded that the advertising campaign “Can’t Skip Portugal” achieved its pro-posed goals, involving and influencing the target audience in the choice of Portugal as a touristic destination.info:eu-repo/semantics/acceptedVersio

Human case of West Nile neuroinvasive disease in Portugal, summer 2015

A case of West Nile virus (WNV) infection was reported in the Algarve region, Portugal, in the first week of September 2015. WNV is known to circulate in Portugal, with occasional reports in horses and birds (2004 to 2011) and very sporadically human cases (in 2004 and in 2010). Here we present the clinical and laboratory aspects related to the first human case of West Nile neuroinvasive disease reported in Portugal

Critical phenomena and quantum phase transition in long range Heisenberg antiferromagnetic chains

Antiferromagnetic Hamiltonians with short-range, non-frustrating interactions are well-known to exhibit long range magnetic order in dimensions, $d\geq 2$ but exhibit only quasi long range order, with power law decay of correlations, in d=1 (for half-integer spin). On the other hand, non-frustrating long range interactions can induce long range order in d=1. We study Hamiltonians in which the long range interactions have an adjustable amplitude lambda, as well as an adjustable power-law $1/|x|^\alpha$, using a combination of quantum Monte Carlo and analytic methods: spin-wave, large-N non-linear sigma model, and renormalization group methods. We map out the phase diagram in the lambda-alpha plane and study the nature of the critical line separating the phases with long range and quasi long range order. We find that this corresponds to a novel line of critical points with continuously varying critical exponents and a dynamical exponent, z<1.Comment: 27 pages, 12 figures. RG flow added. Final version to appear in JSTA

The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients

Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are negative by consecutive reverse transcription polymerase chain reaction (RT-PCR) assays, negative tests are still observed in patients who ultimately relapse. Conversion from negative to positive PCR has been observed after consolidation and found to be a much stronger predictor of relapse. This study reports on 47 APL patients to determine the correlation between minimal residual disease (MRD) status and clinical outcome in our cohort of patients. Design and Methods. The presence of PML-RAR alpha t transcripts was investigated in 47 APL patients (37 adults and 10 children) using a semi-nested reverse transcriptase-polymerase chain reaction to evaluate the prognostic value of RT-PCR tests. Results. All patients achieved complete clinical remission (CCR) following induction treatment with all-trans retinoic acid (ATRA) and chemotherapy (CHT) or ATRA alone. Patients were followed up between 2 and 117.6 months (median: 37 months). Relapses occurred in 11 patients (9 adults and 2 children) between 11.4 and 19 months after diagnosis (median: 15.1 months) while 36 patients (28 adults and 8 children) remained in CCR, Seventy-five percent of patients carried the PML-RARa long isoform (bcr 1/2) which also predominated among the relapsed cases (9 of 11) but did not associate with any adverse outcome (p = 0.37), For the purpose of this analysis, minimal residual disease tests were clustered into four time-intervals: 0-2 months, 3-5 months, 5-9 months and 10-24 months. Interpretation and Conclusions. Children showed persisting disease for longer than adults during the first 2 months of treatment, At 2 months, 10 (50%) of 20 patients who remained in CCR and 4 (80%) of 5 patients who subsequently relapsed were positive. Patients who remained in CCR had repeatedly negative results beyond 5.5 months from diagnosis. A positive MRD test preceded relapse in 3 of 4 tested patients. The ability of a negative test to predict CCR (predictive negative value, PNV) was greater after 6 months (> 83%), while the ability of a positive test to predict relapse (predictive positive value, PPV) was most valuable only beyond 10 months (100%). This study (i) highlights the prognostic value of RT-PCR monitoring after treatment of APL patients but only from the end of treatment, (ii) shows an association between conversion to a positive test and relapse and (iii) suggests that PCR assessments should be carried out at 3-month intervals to provide a more accurate prediction of hematologic relapses but only after the end of treatment, (C) 2001, Ferrata Storti Foundatio

Recomendação para o controle químico da helmintosporiose do sorgo (Exserohilum turcicum).

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Uso integrado da resistência genética e aplicação de fungicidas para o manejo da antracnose do sorgo.

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Aplicação foliar de fungicidas e incidência de grãos ardidos e fumonisinas totais em milho.

Foram conduzidos dois ensaios nas áreas experimentais da Embrapa Milho e Sorgo, em Sete Lagoas, MG, e da empresa Círculo Verde Assessoria Agronômica e Pesquisa, em Luís Eduardo Magalhães (LEM), BA, na safra 2010/11. Em Sete Lagoas, foi utilizado a cultivar BRS1035 submetido à aplicação dos fungicidas azoxistrobina + ciproconazole (0,30 + 0,60 l.ha-1), piraclostrobina + epoxiconazole (0,75 + 0,50 l.ha-1) e trifloxistrobina + tebuconazole (0,60 + 0,60 l.ha-1). Os tratamentos consistiram de 0, 1, 2, e 3 aplicações de cada fungicida em diferentes fases do ciclo da cultura, com três repetições. No tratamento testemunha não foi realizada aplicação de fungicidas. No ensaio conduzido em LEM, o híbrido 30F53H foi submetido à aplicação com quatro fungicidas. Os tratamentos consistiram da aplicação dos fungicidas picoxistrobina + ciproconazol (0,30 + 0,60 l.ha-1), piraclostrobina + epoxiconazole (0,75 + 0,50 l.ha- 1), trifloxistrobina + tebuconazole (0,60 + 0,60 l.ha-1) e azoxistrobina + ciproconazole (0,30 + 0,60 l.ha-1) em zero, uma (V10) e duas (V10 + 15 dias após a primeira) aplicações, com três repetições. Ao final do ciclo da cultura, foi realizada a colheita manual de espigas, e, após a homogeneização da massa de grãos, foram retiradas duas amostras de 500 g de cada parcela. Em ambos os ensaios, não foi observada diferença significativa entre os tratamentos submetidos a zero, uma e duas aplicações com os diferentes fungicidas testados quanto à incidência de grãos ardidos e fumonisinas totais nos grãos. Quanto à incidência de fungos associados aos grãos, foi verificada diferença significativa apenas para o fator tipo de grão (ardido e assintomático). Foi detectada elevada incidência de fungos do gênero Fusarium sp. tanto em grãos ardidos quanto em grãos assintomáticos, embora tenha sido detectada presença estatisticamente superior nos grãos ardidos (sintomáticos). Penicillium sp. foi detectado em maior frequência em grãos assintomáticos, e Stenocarpella sp. esteve predominantemente associada a grãos ardidos. Não houve diferença para a incidência de Aspergillus sp. entre os tratamentos. Esses resultados demonstram uma baixa eficiência da aplicação de fungicidas na redução da incidência de patógenos fúngicos nas espigas, na incidência de grãos ardidos e nos teores de fumonisinas totais nos grãos.bitstream/item/126043/1/bol-114.pd

Rotação de cultivares como uma estratégia para o manejo da antracnose do sorgo.

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