83 research outputs found
Development and Evaluation of Omni channel service based on Internet of Things for Hospitals
Omni-channel services based on the Internet of Things (IoT) technologies have emerged in various business environments. To enhance hospital’s service quality and maximize benefits as well as provide seamless customer experience, this study applies IoT technology based on NFC, iBeacon(inclusing wearable devices) as an omnichannel service for integration of online and offline channel in hospital. First, we develop services based on IoT technology for omni channel of the hospital. Then, we will evaluate omni channel services from a CRM and BPI point of view through interview. To develop the IoT technology based on NFC, iBeacon, we conducted action research. The five phases in action research framework research include diagnosing, action planning, action taking, evaluation, and specifying learning phases. In this study, we focus on action planning, action taking, evaluation. At the action planning phases, eleven service models based on IoT technology for omni channel for hospital were designed. Service models were applied to the hospital by installing tags and beacons at the third phase. At the fourth phases, service models issues and knowledge on the whole application process were derived and summarized with respect to CRM (Customer Relationship Management) and BPI (Business Process Innovation) of hospital
Truth, falsehood, and reciprocity in Pindar and Aeschylus
The numerous studies of truth and falsehood in Greek thought are quite varied in scope and methodology but tend to fall into one of two categories: detailed word-studies that identify and explicate terms for truth and falsehood, usually in the poetry of Homer and Hesiod, or general explorations of the nature of truth and the processes for its formation across Greek literature. This study seeks to fill the gaps left by these two approaches by combining meticulous examination of Aeschylus' and Pindar's terms for truth and falsehood with a broader discussion of how truth and falsehood operate in their poetry. The focus is on passages that explicitly mention truth and falsehood, an approach that generates conclusions both about the use of these terms and about the influence of these concepts on a poet's self-conscious purpose. The major claims are that Aeschylean and Pindaric truth and falsehood are generically determined concepts and are incorporated in relationships or cycles of reciprocity integral to each poet's genre. Thus truth and falsehood cannot be understood without adequate consideration of genre and purpose. As a praise poet, Pindar's aims are twofold: he must convince his audience of his devotion to the person he is tasked with praising (the laudandus) and he must persuade them that his claims about the laudandus are accurate. He thus incorporates truth into the relationship he constructs between himself and the laudandus by espousing a truth that combines sincerity with accuracy and by denouncing falsehood for the threat it poses to this relationship. Aeschylus likewise assimilates truth and falsehood to his poetic purpose. Since his primary concern as a tragedian is to present plots of retributive violence, ideas about truth and falsehood appear in contexts of belief or disbelief. Thus characters who speak truth are believed or disbelieved in accordance with what will facilitate plots about violent reprisal; similarly, whether characters successfully or unsuccessfully enact a deception depends on what is required to tell a story of reciprocal aggression
Case Study on the Enterprise Microblog Usage: Focusing on Knowledge Learning
Knowledge Management Strategy can be classified by codification strategy and personalization strategy (Hansen et. al., 1999), and how to manage the two strategies were always studied. Also, current studies regarding the knowledge management strategy were targeted mostly for major companies, resulting in lack of studies in how it can be applied on SMEs. This research, with the knowledge management strategy suited for SMEs, sets an Enterprise Microblog (EMB), and with the EMB applied on SMEs’ Knowledge Management Strategy, it is reviewed on the perspective of SMEs’ Codification and Personalization Strategies. Through the advanced research regarding Knowledge Management Strategy and EMB, the hypothesis is set that “Depending on the development of the company, the main application of EMB alters from Codification Strategy to Personalization Strategy.” To check the hypothesis, SME that have used the EMB called ‘Yammer’ was analyzed from the data of their foundation until today. The case study has implemented longitudinal analysis which divides the period when the EMBs were used into three stages and analyzes the contents. As the result of the study, this suggests a substantial implication regarding the application of Knowledge Management Strategy and its Knowledge Management System that is suitable for SME
A Microchip for High-throughput Axon Growth Drug Screening
It has been recently known that not only the presence of inhibitory molecules associated with myelin but also the reduced growth capability of the axons limit mature central nervous system (CNS) axonal regeneration after injury. Conventional axon growth studies are typically conducted using multi-well cell culture plates that are very difficult to use for investigating localized effects of drugs and limited to low throughput. Unfortunately, there is currently no other in vitro tool that allows investigating localized axonal responses to biomolecules in high-throughput for screening potential drugs that might promote axonal growth. We have developed a compartmentalized neuron culture platform enabling localized biomolecular treatments in parallel to axons that are physically and fluidically isolated from their neuronal somata. The 24 axon compartments in the developed platform are designed to perform four sets of six different localized biomolecular treatments simultaneously on a single device. In addition, the novel microfluidic configuration allows culture medium of 24 axon compartments to be replenished altogether by a single aspiration process, making high-throughput drug screening a reality
Fabrication of Functionalized Double-Lamellar Multifunctional Envelope-Type Nanodevices Using a Microfluidic Chip with a Chaotic Mixer Array
Multifunctional envelope-type nanodevices (MENDs) are very promising non-viral gene delivery vectors because they are biocompatible and enable programmed packaging of various functional elements into an individual nanostructured liposome. Conventionally MENDs have been fabricated by complicated, labor-intensive, time-consuming bulk batch methods. To avoid these problems in MEND fabrication, we adopted a microfluidic chip with a chaotic mixer array on the floor of its reaction channel. The array was composed of 69 cycles of the staggered chaotic mixer with bas-relief structures. Although the reaction channel had very large Péclet numbers (>105) favorable for laminar flows, its chaotic mixer array led to very small mixing lengths (<1.5 cm) and that allowed homogeneous mixing of MEND precursors in a short time. Using the microfluidic chip, we fabricated a double-lamellar MEND (D-MEND) composed of a condensed plasmid DNA core and a lipid bilayer membrane envelope as well as the D-MEND modified with trans-membrane peptide octaarginine. Our lab-on-a-chip approach was much simpler, faster, and more convenient for fabricating the MENDs, as compared with the conventional bulk batch approaches. Further, the physical properties of the on-chip-fabricated MENDs were comparable to or better than those of the bulk batch-fabricated MENDs. Our fabrication strategy using microfluidic chips with short mixing length reaction channels may provide practical ways for constructing more elegant liposome-based non-viral vectors that can effectively penetrate all membranes in cells and lead to high gene transfection efficiency
Protein homeostasis and aging in neurodegeneration
Genetic and environmental factors responsible for numerous neurodegenerative diseases vary between disorders, yet age remains a universal risk factor. Age-associated decline in protein homeostasis, or proteostasis, enables disease-linked proteins to adopt aberrant tertiary structures, accumulate as higher-ordered aggregates, and cause a myriad of cellular dysfunctions and neuronal death. However, recent findings suggest that the assembly of disease proteins into tightly ordered aggregates can significantly delay proteotoxic onset. Furthermore, manipulation of metabolic pathways through key signaling components extends lifespan, bolsters proteostasis networks, and delays the onset of proteotoxicity. Thus, understanding the relationship between proteostasis and aging has provided important insights into neurodegeneration
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Parthenogenesis in Hesiod’s Theogony
This article examines female asexual reproduction, or parthenogenesis, in Hesiod’s Theogony and argues that it is a symptom of the unprecedented and unparalleled female presence Hesiod inserts into his cosmos. This presence in turn reflects Hesiod’s incorporation of gender difference and conflict as indispensable both to the creation and, paradoxically, to the stability of the universe. Five of Hesiod’s deities reproduce parthenogenetically: Chaos, Gaea, Night, Strife, and Hera, of whom all but the sexually indeterminate Chaos are female. Hesiod’s male gods have no analogous reproductive ability. The parthenogenetic phases of the early goddesses form much of the fundamental shape and character of the universe, while in the case of Hera, parthenogenesis serves initially as an act of defiance against Zeus but ultimately enforces his reign. Parthenogenesis does not have these functions in either the Near Eastern or other Greek cosmogonic traditions, a difference that reflects Hesiod’s greater emphasis on female participation in his succession myth. Yet Hesiod’s cosmogonic narrative, like others, culminates in the lasting reign of a male god, Zeus. In this context parthenogenesis is a manifestation of female creation, which ultimately reinforces the stability of a male sovereign. The relative prominence of parthenogenesis in the Theogony reflects Hesiod’s emphasis on gender difference and conflict as indispensable to a cosmos in which conflict and concord coexist as equal partners in creation and stability.This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]
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