Hábitos y comportamiento del trips (Chaetanaphothrips signipennis bagnall) y acaro depredador (Amblyseius swirskii athias-henriot) en el cultivo establecido de banano orgánico (Musa paradisiaca L.).

La presente investigación propone estudiar los hábitos y comportamiento del trips de la mancha roja (Chaetanaphothrips signipennis Bagnall) y ácaro depredador (Amblyseius swirskii Athias Henriot) en cultivo establecido de banano orgánico (Musa paradisiaca L); para el estudio se seleccionó un lote de 10.5 ha, se eligió 180 hijos de altura de planta entre 1 a 1,5 metros, se evaluó semanalmente por 8 semanas mediante conteos en el tercio medio-superior, bases de inserción las hojas con el pseudotallo «chantas» considerando los siguientes indicadores: índice medio de infestación del trips de la mancha roja, índice medio de depredación del ácaro; el esquema de muestreo en zigzag. Para el caso del ácaro, se utilizó la metodología de la empresa Koppert. El ácaro, es un depredador generalista, sus etapas del ciclo de vida, lo realiza en los hijos de sucesión, el tercio medio y superior de la planta es predilecto para conformar sus colonias, bases peciolares del pseudotallo y «chantas» depredando a sus enemigos naturales. El IMDp fue entre 1,117 y 9,361; una temperatura media: 25,28°C; humedad ambiental: 80,5%; velocidad del viento: 2 km/h; Se concluye los hábitos y comportamientos del fitófago se alojan en el tercio superior, bases peciolares del pseudotallo son lucífugos; el ácaro depredador se ubica en el tercio medio superior «chantas» y bases peciolares del pseudotallo. Previo a la liberación del ácaro depredador es conveniente realizar el riego suprafoliar, mientras que el riego subfoliar se lo puede realizar sin ningún inconveniente se debe coordinar con los responsables del riego en el cultivo de banano orgánico. También se debe considerar en el momento del muestreo del fitófago y del depredador hacerlo con precaución no destruir las colonias de poblaciones.The present investigation aims to study the habits and behavior of the red rust thrips (Chaetanaphothrips signipennis Bagnall) and predatory mite (Amblyseius swirskii Athias Henriot) in an established crop of organic banana (Musa paradisiaca L). A lot of 10.5 ha and 180 offspring of plant height from 1 to 1.5 meters were selected for this study. In addition, the populations of red rust thrips and predatory mite were evaluated weekly for 8 weeks by means of counts in the middle-upper third on the bases of leaf insertion with the pseudostem "chantas" considering the average infestation index of red rust thrips (IMI), average index of mite predation (IMDp) and the zigzag sampling scheme. The Koppert company's methodology was used for mite, which is a generalist predator, its life cycle stages are carried out in the succession offspring, the middle and upper third of the plant is favorite to form its colonies, the petiolar bases of the pseudostem and "chantas" predating its natural enemies. The IMDp was between 1.117 and 9.361; average temperature: 25.28°C; environmental humidity: 80.5%; wind speed: 2 km/h. It is concluded that the habits and behaviors of the phytophagous are located in the upper third, pseudostem stalk bases are lucifugous; the predatory mite is located in the upper middle third, "chantas" and pseudostem stalk bases. Before releasing the predatory mite, it is convenient to carry out suprafoliar irrigation, while subfoliar irrigation can be carried out as it is always done with the person who responsible for irrigation in the organic banana crop. It should also be considered at the time of sampling of the phytophagous and predator to do it with caution and not to destroy the colonies of specimens

Reduced Cancer Incidence in Huntington's Disease: Analysis in the Registry Study

Background: People with Huntington's disease (HD) have been observed to have lower rates of cancers. Objective: To investigate the relationship between age of onset of HD, CAG repeat length, and cancer diagnosis. Methods: Data were obtained from the European Huntington's disease network REGISTRY study for 6540 subjects. Population cancer incidence was ascertained from the GLOBOCAN database to obtain standardised incidence ratios of cancers in the REGISTRY subjects. Results: 173/6528 HD REGISTRY subjects had had a cancer diagnosis. The age-standardised incidence rate of all cancers in the REGISTRY HD population was 0.26 (CI 0.22-0.30). Individual cancers showed a lower age-standardised incidence rate compared with the control population with prostate and colorectal cancers showing the lowest rates. There was no effect of CAG length on the likelihood of cancer, but a cancer diagnosis within the last year was associated with a greatly increased rate of HD onset (Hazard Ratio 18.94, p < 0.001). Conclusions: Cancer is less common than expected in the HD population, confirming previous reports. However, this does not appear to be related to CAG length in HTT. A recent diagnosis of cancer increases the risk of HD onset at any age, likely due to increased investigation following a cancer diagnosis

Clinical and genetic characteristics of late-onset Huntington's disease

Background: The frequency of late-onset Huntington's disease (&gt;59 years) is assumed to be low and the clinical course milder. However, previous literature on late-onset disease is scarce and inconclusive. Objective: Our aim is to study clinical characteristics of late-onset compared to common-onset HD patients in a large cohort of HD patients from the Registry database. Methods: Participants with late- and common-onset (30–50 years)were compared for first clinical symptoms, disease progression, CAG repeat size and family history. Participants with a missing CAG repeat size, a repeat size of ≤35 or a UHDRS motor score of ≤5 were excluded. Results: Of 6007 eligible participants, 687 had late-onset (11.4%) and 3216 (53.5%) common-onset HD. Late-onset (n = 577) had significantly more gait and balance problems as first symptom compared to common-onset (n = 2408) (P &lt;.001). Overall motor and cognitive performance (P &lt;.001) were worse, however only disease motor progression was slower (coefficient, −0.58; SE 0.16; P &lt;.001) compared to the common-onset group. Repeat size was significantly lower in the late-onset (n = 40.8; SD 1.6) compared to common-onset (n = 44.4; SD 2.8) (P &lt;.001). Fewer late-onset patients (n = 451) had a positive family history compared to common-onset (n = 2940) (P &lt;.001). Conclusions: Late-onset patients present more frequently with gait and balance problems as first symptom, and disease progression is not milder compared to common-onset HD patients apart from motor progression. The family history is likely to be negative, which might make diagnosing HD more difficult in this population. However, the balance and gait problems might be helpful in diagnosing HD in elderly patients

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases of prospectively collected clinical data on people hospitalized with COVID-19. This dataset was compiled during the COVID-19 pandemic by a network of hospitals that collect data using the ISARIC-World Health Organization Clinical Characterization Protocol and data tools. The database includes data from more than 705,000 patients, collected in more than 60 countries and 1,500 centres worldwide. Patient data are available from acute hospital admissions with COVID-19 and outpatient follow-ups. The data include signs and symptoms, pre-existing comorbidities, vital signs, chronic and acute treatments, complications, dates of hospitalization and discharge, mortality, viral strains, vaccination status, and other data. Here, we present the dataset characteristics, explain its architecture and how to gain access, and provide tools to facilitate its use