Rumen phosphorus metabolism in sheep

8 páginas, 3 tablas.The objective of the present study was to examine the effect of the level of phosphorus (P) intake on ruminal P kinetics in sheep. Twelve Santa Ines male sheep (average body weight 36 kg) were fed a basal diet consisting of roughage (coast cross hay), concentrate mixture (cassava meal, soya bean meal and urea) and a mineral premix. The treatments consisted of the basal diet supplemented with 0, 1.5, 3 or 4.5 g/kg dry matter (DM) of mono-ammonium phosphate to provide increasing P levels representing treatments T0, T1, T2 and T3, respectively. The P content of experimental diets was 1-5; 2.0; 2.5 and 3.0 g P/kg DM, and considered highly deficient, deficient, adequate and in excess, respectively, compared with standard recommended allowances. Animals were injected with (32)P and thereafter samples of blood were collected over 7 days, while samples of rumen fluid and saliva were collected 4 and 6 days after injection. Phosphorus intake affected P concentration in ruminal fluid, whereas P concentration in saliva was not affected. The values for P turnover time in the rumen were 1.42, 1.23, 1.18 and 1.04 days, whereas values of endogenous P entry into the rumen were 1.05, 1.37, 1.53 and 1.91 g/day for T0, T 1, T2 and T3, respectively, both affected by P intake. The specific activity (SA) of P in saliva, rumen and plasma were also all affected by P intake. The relationship between saliva and rumen SA emphasizes that most endogenous P in the rumen came from saliva. The possibility of an extra P source besides saliva contributing to endogenous P in the rumen is discussed. It is concluded from the results that, regardless of P intake, the flow of endogenous P into the rumen contributes to ensure a minimum Supply of this essential element, which may be important in matching the requirements of the rumen microbes.Fundaçao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP Proc. 2004/14532-5) for financial support. Funding was provided, in part, by the Canada Research Chairs Program.Peer reviewe

O papel do enfermeiro na prevenção das lesões na síndrome do pé diabético

The aim was to identify the role of nurses in preventive care for Diabetic Foot injuries. Descriptive-exploratory study, of a quantitative nature. Carried out in a health clinic located in the city of São Paulo, with 65 diabetic patients, between 18 and 90 years old. Among the study participants, the highest percentage of those who showed signs and symptoms of Diabetic Foot Syndrome were among those who had the diagnosis a longer time ago, had greater resistance to changes in habits and adherence to treatment, did not follow the guidelines on foot care and/or had other associated chronic diseases. The nurse is fundamental in early diagnosis, interventions and education on preventive care. The prevention of Diabetic Foot complications depends on the commitment, communication and training of the multidisciplinary team to reduce amputations and morbidity and mortality of diabetics.Objetivou-se identificar o papel do enfermeiro nos cuidados preventivos das lesões do Pé Diabético. Estudo descritivo-exploratório, de natureza quantitativa. Realizado em uma clínica de saúde localizada no município de São Paulo, com 65 pacientes diabéticos, entre 18 e 90 anos. Entre os participantes do estudo, a maior porcentagem dos que apresentavam sinais e sintomas da Síndrome do Pé Diabético, estavam entre os que tiveram o diagnóstico há mais tempo, possuíam maior resistência a mudanças de hábito e adesão ao tratamento, não seguiam as orientações sobre os cuidados com os pés e/ou possuíam outras doenças crônicas associadas. O enfermeiro é fundamental no diagnóstico precoce, intervenções e educação sobre cuidados preventivos. A prevenção das complicações do Pé Diabético depende do empenho, comunicação e treinamento da equipe multidisciplinar para a redução das amputações e morbimortalidade dos diabéticos

O papel do enfermeiro na prevenção das lesões na síndrome do pé diabético

The aim was to identify the role of nurses in preventive care for Diabetic Foot injuries. Descriptive-exploratory study, of a quantitative nature. Carried out in a health clinic located in the city of São Paulo, with 65 diabetic patients, between 18 and 90 years old. Among the study participants, the highest percentage of those who showed signs and symptoms of Diabetic Foot Syndrome were among those who had the diagnosis a longer time ago, had greater resistance to changes in habits and adherence to treatment, did not follow the guidelines on foot care and/or had other associated chronic diseases. The nurse is fundamental in early diagnosis, interventions and education on preventive care. The prevention of Diabetic Foot complications depends on the commitment, communication and training of the multidisciplinary team to reduce amputations and morbidity and mortality of diabetics.Objetivou-se identificar o papel do enfermeiro nos cuidados preventivos das lesões do Pé Diabético. Estudo descritivo-exploratório, de natureza quantitativa. Realizado em uma clínica de saúde localizada no município de São Paulo, com 65 pacientes diabéticos, entre 18 e 90 anos. Entre os participantes do estudo, a maior porcentagem dos que apresentavam sinais e sintomas da Síndrome do Pé Diabético, estavam entre os que tiveram o diagnóstico há mais tempo, possuíam maior resistência a mudanças de hábito e adesão ao tratamento, não seguiam as orientações sobre os cuidados com os pés e/ou possuíam outras doenças crônicas associadas. O enfermeiro é fundamental no diagnóstico precoce, intervenções e educação sobre cuidados preventivos. A prevenção das complicações do Pé Diabético depende do empenho, comunicação e treinamento da equipe multidisciplinar para a redução das amputações e morbimortalidade dos diabéticos

Metodologias de ensino na educação a distância em ciências da saúde: formação lato sensu

The aim was to identify the role of teaching methodologies used in lato sensu courses in Distance Education in Health Sciences. Descriptive qualitative research. Research subjects: professors/coordinators of lato sensu courses in the areas of health in Distance Education. A form on teaching tools and methodologies and a semi-structured interview were used. For data analysis, the content analysis method was used under the concepts of Vygotsky's socio-interactionist theory. The data raised the tools used in the teaching platforms. The analysis of the interviews resulted in four categories. These data showed the difficulties, experiences and expectations of teachers/coordinators. Distance Education provides expansion and deepening of knowledge. There is concern about the quality of teaching, directed to the need to adapt the methodologies applied to the use of different tools. Distance Education provides expansion of access to professional qualification, consequently improving health care for the population.Objetivou-se identificar o papel das metodologias de ensino utilizadas em cursos lato sensu em Educação a Distância nas Ciências da Saúde. Pesquisa qualitativa descritiva. Sujeitos da pesquisa: professores/coordenadores de cursos lato sensu nas áreas da saúde em Educação a Distância. Foram utilizados formulário sobre ferramentas e metodologias de ensino e entrevista semiestruturada. Para análise dos dados foi utilizado o método de análise de conteúdo sob os conceitos da teoria sócio-interacionista de Vygotsky. Os dados levantaram as ferramentas utilizadas nas plataformas de ensino. A análise das entrevistas resultou em quatro categorias. Esses dados mostraram as dificuldades, experiências e expectativas dos professores/coordenadores. A Educação a Distância proporciona expansão e aprofundamento de conhecimento. Existe preocupação quanto a qualidade do ensino, direcionada a necessidade de adequação das metodologias aplicadas ao uso das diferentes ferramentas. A Educação a Distância proporciona ampliação ao acesso à qualificação profissional, consequentemente melhorando a assistência de saúde à população

Metodologias de ensino na educação a distância em ciências da saúde: formação lato sensu

The aim was to identify the role of teaching methodologies used in lato sensu courses in Distance Education in Health Sciences. Descriptive qualitative research. Research subjects: professors/coordinators of lato sensu courses in the areas of health in Distance Education. A form on teaching tools and methodologies and a semi-structured interview were used. For data analysis, the content analysis method was used under the concepts of Vygotsky's socio-interactionist theory. The data raised the tools used in the teaching platforms. The analysis of the interviews resulted in four categories. These data showed the difficulties, experiences and expectations of teachers/coordinators. Distance Education provides expansion and deepening of knowledge. There is concern about the quality of teaching, directed to the need to adapt the methodologies applied to the use of different tools. Distance Education provides expansion of access to professional qualification, consequently improving health care for the population.Objetivou-se identificar o papel das metodologias de ensino utilizadas em cursos lato sensu em Educação a Distância nas Ciências da Saúde. Pesquisa qualitativa descritiva. Sujeitos da pesquisa: professores/coordenadores de cursos lato sensu nas áreas da saúde em Educação a Distância. Foram utilizados formulário sobre ferramentas e metodologias de ensino e entrevista semiestruturada. Para análise dos dados foi utilizado o método de análise de conteúdo sob os conceitos da teoria sócio-interacionista de Vygotsky. Os dados levantaram as ferramentas utilizadas nas plataformas de ensino. A análise das entrevistas resultou em quatro categorias. Esses dados mostraram as dificuldades, experiências e expectativas dos professores/coordenadores. A Educação a Distância proporciona expansão e aprofundamento de conhecimento. Existe preocupação quanto a qualidade do ensino, direcionada a necessidade de adequação das metodologias aplicadas ao uso das diferentes ferramentas. A Educação a Distância proporciona ampliação ao acesso à qualificação profissional, consequentemente melhorando a assistência de saúde à população

Phase transitions in tumor growth VI: Epithelial–Mesenchymal transition

Herewith we discuss a network model of the epithelial–mesenchymal transition (EMT) based on our previous proposed framework. The EMT appears as a “first order” phase transition process, analogous to the transitions observed in the chemical–physical field. Chiefly, EMT should be considered a transition characterized by a supercritical Andronov–Hopf bifurcation, with the emergence of limit cycle and, consequently, a cascade of saddle-foci Shilnikov's bifurcations. We eventually show that the entropy production rate is an EMT-dependent function and, as such, its formalism reminds the van der Waals equation.Fil: Guerra, A.. Universidad de La Habana; CubaFil: Rodriguez, D. J.. Universidad de La Habana; CubaFil: Montero, S.. Medical Sciences University Of Havana; CubaFil: Betancourt Mar, J. A.. Universidad de La Habana; CubaFil: Martín Pardo, Reinaldo Román. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina. Mexican Institute Of Complex Systems. Tamaulipas; MéxicoFil: Silva Lamar, Eduardo. Universidad de La Habana; CubaFil: Bizzarri, María Julia. Universidad de La Habana; CubaFil: Cocho, G.. Universidad Nacional Autónoma de México; MéxicoFil: Mansilla, R.. Universidad Nacional Autónoma de México; MéxicoFil: Nieto Villar, José Manuel. Universidad de La Habana; Cub

Characteristics of resistance training-based protocols in older adults with sarcopenic obesity: a scoping review of training procedure recommendations

Background: Sarcopenic obesity (SO) is a clinical and functional disease characterized by the coexistence of obesity and sarcopenia. Resistance training (RT) characteristics for older adults with sarcopenia or obesity are already well established in the scientific literature. Nonetheless, we still do not know how detailed the RT protocols are described for older adults with SO. Therefore, we aimed to analyze the characteristics of RT programs, including each of their variables, recommended for older adults with SO. Methods: This is a scoping review study that was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis for Scoping Reviews. The search was carried out until November 2022 in PubMed/MEDLINE, EMBASE, Cochrane Library, Web of Science, Scopus, LILACS, Google Scholar, and medRxiv databases. The studies included SO diagnosis and RT as an intervention strategy. The RT variables analyzed were as follows: exercise selection, the volume of sets, the intensity of load, repetition cadence, rest interval between sets, and weekly frequency. Results: A total of 1,693 studies were identified. After applying the exclusion criteria, 15 studies were included in the final analysis. The duration of the RT intervention ranged from 8 to 24 weeks. All studies included full-body routines, with single/multi-joint exercises. Regarding the volume of sets, some studies fixed it in three sets, whereas others varied between one and three sets. The load was reported by repetition range and the weight lifted, elastic-band color/resistance, percentage of one repetition maximum, or perceived exertion scale. Repetition cadence was fixed in some studies, while it was self-selected between concentric and eccentric phases in others. The interval between sets of rest varied from 30 to 180 s. All studies reported progression overload during the interventions.info:eu-repo/semantics/publishedVersio

MMP1 and MMP7 as Potential Peripheral Blood Biomarkers in Idiopathic Pulmonary Fibrosis

Naftali Kaminski and colleagues find increased levels of specific proteins in the bloodstream of individuals with idiopathic pulmonary fibrosis, and suggest that these proteins may ultimately provide a biomarker for the disease

Daylight entanglement-based quantum key distribution with a quantum dot source

Entanglement-based quantum key distribution can enable secure communication in trusted node-free networks and over long distances. Although implementations exist both in fiber and in free space, the latter approach is often considered challenging due to environmental factors. Here, we implement a quantum communication protocol during daytime for the first time using a quantum dot source. This technology presents advantages in terms of narrower spectral bandwidth-beneficial for filtering out sunlight-and negligible multiphoton emission at peak brightness. We demonstrate continuous operation over the course of three days, across an urban 270 m-long free-space optical link, under different light and weather conditions