On the role of microsomal aldehyde dehydrogenase in metabolism of aldehydic products of lipid peroxidation

AbstractTo elucidate a possible role of membrane-bound aldehyde dehydrogenase in the detoxication of aldehydic products of lipd peroxidation, the substrate specificity of the highly purified microsomal enzyme was investigated. The aldehyde dehydrogenase was active with different aliphatic aldehydes including 4-hydroxyalkenals, but did not react with malonic dialdehyde. When Fe/ADP-ascorbate-induced lipid peroxidation of arachidonic acid was carried out in an in vitro system, the formation of products which react with microsomal aldehyde dehydrogenase was observed parallel with malonic dialdehyde accumulation

Conditionally university student readiness of the person to self-development by means of physical education

The article discusses conditionality desire of students to self-development and the formation of competence readiness in this area of knowledge in classes of P.E. Designed levels determination of formation of readiness for self-development of students of the university. The system contributes to self-realization of the personality of students, formation of physical culture and sports competences and the competence of self-development. The fact is that the current situation in the development of the society and the analysis of the world's sociocultural and educational trends indicate that in recent years, various aspects of the individual's behavior towards his health have become the object of intense public attention and the subject of interdisciplinary research in many highly developed countries under the slogan: "Health is not everything, but everything without health is nothing". Hence the tasks of the student's personality self-development during the intensive preparation for professional activity at the university are aimed at maintaining their own health and improving their physical fitness, considering formation of professional motor skills for effective mastering the future profession and career growth after graduation.peer-reviewe

Mapping out a future for ungulate migrations

Migration of ungulates (hooved mammals) is a fundamental ecological process that promotes abundant herds, whose effects cascade up and down terrestrial food webs. Migratory ungulates provide the prey base that maintains large carnivore and scavenger populations and underpins terrestrial biodiversity (fig. S1). When ungulates move in large aggregations, their hooves, feces, and urine create conditions that facilitate distinct biotic communities. The migrations of ungulates have sustained humans for thousands of years, forming tight cultural links among Indigenous people and local communities. Yet ungulate migrations are disappearing at an alarming rate (1). Efforts by wildlife managers and conservationists are thwarted by a singular challenge: Most ungulate migrations have never been mapped in sufficient detail to guide effective conservation. Without a strategic and collaborative effort, many of the world's great migrations will continue to be truncated, severed, or lost in the coming decades. Fortunately, a combination of animal tracking datasets, historical records, and local and Indigenous knowledge can form the basis for a global atlas of migrations, designed to support conservation action and policy at local, national, and international levels