5,143 research outputs found

    Comparison of Grain Sources (Barley, White Corn, and Yellow Corn) for Swine Diets and Their Effects on Meat Quality and Production Traits

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    Efficient pork production is a necessity for an economically viable swine industry. Number two yellow corn is considered the primary energy source for swine diets in the Midwest. Despite the low protein content, corn is considered one of the most economical feed stuffs available to the swine production system. Barley is a high fiber that has approximately 89% of the energy content of corn. While barley contains a higher protein and amino acid level than corn, animal performance is expected to be depressed due to the high fiber content. Because barley lacks the carotene content that yellow corn possesses, it has been hypothesized that barley-fed pigs will yield higher meat and fat quality that is desired by export markets. White corn was used in this trial to determine its contribution to meat quality and growth traits. An experiment was conducted to evaluate the effect of energy source on performance and carcass traits of pigs. Diet treatments (primary energy source) were: 1) yellow corn, 2) white corn, 3) 1/3 yellow corn, 2/3 white corn, 4) 2/3 yellow corn, 1/3 white corn, 5) barley. Pigs completing the trial were from two sires lines, Duroc (n=500) and Hamp x Duroc (n=499), that were mated to PIC 1055 females. Pigs were randomly allocated to pens based on genetic type and gender using a 2 x 2 x 5 factorial arrangement with two genetic types, two sexes (barrows and gilts) and five treatments. Animals fed these diets differing in energy source did not express a difference in average daily gain, average daily feed intake, feed-to-gain ratio, backfat depth or percent fat free lean. However, barley-fed pigs did have a smaller (p \u3c .05) loin muscle area than pigs fed corn-based diets. Diet did not have an effect on sensory panel traits for tenderness or chewiness and limited differences were observed for juiciness, flavor, and off-flavor. Percentage loin purge, and cooking loss did not differ among diets fed to the pigs with minimal difference noted for color values. Pigs fed barley diets did have lower iodine value content within the subcutaneous fat indicating that the fat is of firmer quality. Results of this trial suggest that barley does not have an advantage in meat quality traits when compared to traditional corn-based diets. Barley does however have a significant impact on the hardness of pork fat, but does not have a significant effect on subjective color values

    Clinical and cytogenetic survey of 39 individuals with Prader-Labhart-Willi syndrome

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    In a clinical and cytogenetic survey of 39 individuals with Prader-Labhart-Willi syndrome (PLWS) (23 males and 16 females ranging in age from 2 weeks to 39 years), an interstitial deletion of chromosome 15 (breakpoints q11 and q13) was identified in 21 cases and apparently normal chromosomes in the remainder. Studies of parental chromosome 15 variants showed that the del[15q] was paternal in origin, although chromosomes of both parents were normal. All chromosome deletions were de novo events. Possible causes for the chromosome deletion and the role of chromosome rearrangements in individuals with PLWS are discussed. Clinical characteristics of the deletion and nondeletion groups were recorded and compared with 124 individuals reported in the literature. Individuals with the chromosome deletion were found to have lighter hair, eye, and skin color, greater sun sensitivity, and higher intelligence scores than individuals with normal chromosomes. Correlation studies of metacarpophalangeal pattern profile variables and dermatoglyphic findings indicate apparent homogeneity of the deletion group and heterogeneity of individuals with PLWS and normal chromosomes

    Alignment of patient and primary care practice member perspectives of chronic illness care: a cross-sectional analysis

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    Polly H. Noel and Luci K. Leykum are with the South Texas Veterans Health Care System, 7400 Merton Minter Blvd, San Antonio, TX 78229, USA -- Polly H. Noel, Ray F. Palmer, Raquel L. Romero, Luci K. Leykum, Holly J. Lanham, and Krista W. Bowers are with the Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229, USA -- Michael L. Parchman is with the MacColl Center for Healthcare Innovation, Group Health Research Institute, Group Health Cooperative, 1730 Minor Ave 1600, Seattle, WA 98101, USA -- Holly J. Leykum is with the The McCombs School of Business, The University of Texas at Austin, 2110 Speedway, Stop B6000, Austin, TX 78712, USA -- John E. Zeber is with the Central Texas Veterans Health Care System, 1901 S. 1st St, Temple, TX 76504, USA and Scott and White Healthcare Center for Applied Health Research, 2401 S. 31st St, Temple, TX 76508, USABackground: Little is known as to whether primary care teams’ perceptions of how well they have implemented the Chronic Care Model (CCM) corresponds with their patients’ own experience of chronic illness care. We examined the extent to which practice members’ perceptions of how well they organized to deliver care consistent with the CCM were associated with their patients’ perceptions of the chronic illness care they have received. Methods: Analysis of baseline measures from a cluster randomized controlled trial testing a practice facilitation intervention to implement the CCM in small, community-based primary care practices. All practice “members” (i.e., physician providers, non-physician providers, and staff) completed the Assessment of Chronic Illness Care (ACIC) survey and adult patients with 1 or more chronic illnesses completed the Patient Assessment of Chronic Illness Care (PACIC) questionnaire. Results: Two sets of hierarchical linear regression models accounting for nesting of practice members (N = 283) and patients (N = 1,769) within 39 practices assessed the association between practice member perspectives of CCM implementation (ACIC scores) and patients’ perspectives of CCM (PACIC). ACIC summary score was not significantly associated with PACIC summary score or most of PACIC subscale scores, but four of the ACIC subscales were consistently associated with PACIC summary score and the majority of PACIC subscale scores after controlling for patient characteristics. The magnitude of the coefficients, however, indicates that the level of association is weak. Conclusions: The ACIC and PACIC scales appear to provide complementary and relatively unique assessments of how well clinical services are aligned with the CCM. Our findings underscore the importance of assessing both patient and practice member perspectives when evaluating quality of chronic illness care.Information, Risk, and Operations Management (IROM)[email protected]

    A stochastic movement simulator improves estimates of landscape connectivity

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    Acknowledgments This publication issued from the project TenLamas funded by the French MinistĂšre de l'Energie, de l'Ecologie, du DĂ©veloppement Durable et de la Mer through the EU FP6 BiodivERsA Eranet; by the Agence Nationale de la Recherche (ANR) through the open call INDHET and 6th extinction MOBIGEN to V. M. Stevens, M. Baguette, and A. Coulon, and young researcher GEMS (ANR-13-JSV7-0010-01) to V. M. Stevens and M. Baguette; and by a VLIR-VLADOC scholarship awarded to J. Aben. L. Lens, J. Aben, D. Strubbe, and E. Matthysen are grateful to the Research Foundation Flanders (FWO) for financial support of fieldwork and genetic analysis (grant G.0308.13). V. M. Stevens and M. Baguette are members of the “Laboratoire d'Excellence” (LABEX) entitled TULIP (ANR-10-LABX-41). J. M. J. Travis and S. C. F. Palmer also acknowledge the support of NERC. A. Coulon and J. Aben contributed equally to the work.Peer reviewedPublisher PD

    Patient‐Defined Goals for the Treatment of Severe Aortic Stenosis: A Qualitative Analysis

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    Patients with severe aortic stenosis (AS) at high risk for aortic valve replacement are a unique population with multiple treatment options, including medical therapy, surgical aortic valve replacement and transcatheter aortic valve replacement (TAVR). Traditionally, in elderly populations, goals of treatment may favour quality of life over survival. Professional guidelines recommend that clinicians engage patients in shared decision making, a process that may lead to decisions more aligned with patient-defined goals of care. Goals of care for high-risk patients with AS are not well defined in the literature, and patient-reported barriers to shared decision making highlight the need for explicit encouragement from clinicians for patient involvement

    Improving reintroduction success in large carnivores through individual-based modelling: How to reintroduce Eurasian lynx (Lynx lynx) to Scotland

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    Globally, large carnivores have been heavily affected by habitat loss, fragmentation and persecution, sometimes resulting in local extinctions. With increasing recognition of top-down trophic cascades and complex predator- prey dynamics, reintroductions are of growing interest for restoration of ecosystem functioning. Many re- introductions have however failed, in part due to poor planning and inability to model complex eco-evolutionary processes to give reliable predictions. Using the case study of Eurasian lynx (Lynx lynx), a large predator being considered for reintroduction to Scotland, we demonstrate how an individual-based model that integrates demography with three distinct phases of dispersal (emigration, transfer and settlement) can be used to explore the relative suitability of three geographically-distant potential reintroduction sites, multi-site reintroductions and two founding population sizes. For a single-site reintroduction of 10 lynx, our simulation results show a clear hierarchy of suitability across all metrics. Reintroduction in the Kintyre Peninsula (west coast) consistently performed best, with a probability of population persistence at year 100 of 83%, and the Scottish component of Kielder Forest (southern Scotland) worst, with only a 21% chance of population persistence to year 100. Simultaneous two-site reintroduction in the Kintyre Peninsula and in Aberdeenshire (near the east coast) of 32 lynx gave a 96% persistence at 100 years. Our model was highly sensitive to survival, particularly of adults, highlighting this parameter's importance for reintroduction success. The results strongly indicate the potential viability of Eurasian lynx reintroduction to Scotland given the current cover of suitable woodland habitat. More generally, our work demonstrates how emerging modelling approaches incorporating increased realism in re- presenting species' demography, ecology and dispersal can have high value for quick, inexpensive assessment of likely reintroduction success and for selection between alternative strategies.REF Compliant by Deposit in Stirling's Repositor

    Thermophysical properties of the lanthanide sesquisulfides. III. Determination of Schottky and lattice heat‐capacity contributions of γ‐phase Sm2S3 and evaluation of the thermophysical properties of the γ‐phase Ln2S3 subset

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    We report the experimental heat capacity of γ‐phase Sm2S3 and derived thermophysical properties at selected temperatures. The entropy, enthalpy increments, and Gibbs energy function are 21.50R, 3063R⋅K, and 11.23R at 298.15 K. The experimental heat capacity is made up of lattice and electronic (Schottky) contributions. The lattice contribution is determined for all γ‐phase lanthanide sesquisulfides (Ln2S3 ) using the Komada/Westrum model. The difference between the experimental heat capacity and the deduced lattice heat capacity is analyzed as the Schottky contribution. Comparisons are made between the calorimetric Schottky contributions and those determined based on crystal‐field electronic energy levels of Ln3+ ions in the lattice and between the Schottky contributions obtained from the empirical volumetric priority approach and from the Komada/Westrum theoretical approach. Predictions for the thermophysical properties of γ‐phase Eu2S3 and γ‐phase Pm2S3 (unavailable for experimental determination) are also presented.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/71137/2/JCPSA6-96-8-6149-1.pd

    Passive \u3cem\u3er\u3c/em\u3eGE or Developmental Gene-Environment Cascade? An Investigation of the Role of Xenobiotic Metabolism Genes in the Association Between Smoke Exposure During Pregnancy and Child Birth Weight

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    There is considerable evidence that smoke exposure during pregnancy (SDP) environmentally influences birth weight after controlling for genetic influences and maternal characteristics. However, maternal smoking during pregnancy—the behavior that leads to smoke exposure during pregnancy—is also genetically-influenced, indicating the potential role of passive gene-environment correlation. An alternative to passive gene-SDP correlation is a cascading effect whereby maternal and child genetic influences are causally linked to prenatal exposures, which then have an ‘environmental’ effect on the development of the child’s biology and behavior. We describe and demonstrate a conceptual framework for disentangling passive rGE from this cascading GE effect using a systems-based polygenic scoring approach comprised of genes shown to be important in the xenobiotic (substances foreign to the body) metabolism pathway. Data were drawn from 5044 families from the Avon Longitudinal Study of Parents and Children with information on maternal SDP, birth weight, and genetic polymorphisms in the xenobiotic pathway. Within a k-fold cross-validation approach (k = 5), we created weighted maternal and child polygenic scores using 18 polymorphisms from 10 genes that have been implicated in the xenobiotic metabolism pathway. Mothers and children shared variation in xenobiotic metabolism genes. Amongst mothers who smoked during pregnancy, neither maternal nor child xenobiotic metabolism polygenic scores were associated with a higher likelihood of smoke exposure during pregnancy, or the severity of smoke exposure during pregnancy (and therefore, neither proposed mechanism was supported), or with child birth weight. SDP was consistently associated with lower child birth weight controlling for the polygenic scores, maternal educational attainment, social class, psychiatric problems, and age. Limitations of the study design and the potential of the framework using other designs are discussed

    Thermophysical properties of the lanthanide sesquisulfides. IV. Schottky contributions, magnetic, and electronic properties of ϔ‐phase Yb2S3 and Lu2S3

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    The heat capacities of ϔ‐phase Yb2S3 and Lu2S3 have been determined from 6 to 350 K and their thermodynamic properties evaluated. The resolution of the Schottky and magnetic properties by evaluation of the lattice heat capacity is shown to be in accord with spectroscopically determined energy levels. The lattice heat capacity of Yb2S3 was determined by means of the Komada–Westrum phonon distribution model. Excess heat‐capacity contributions were thus evaluated and analyzed as Schottky and magnetic heat capacities. A phase transition associated with magnetic ordering was detected in the heat capacity of Yb2S3 near 7 K with an entropy content of 0.68R. The entropies at 298.15 K are 22.77R and 19.74R for Yb2S3 and for Lu2S3.  Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/70016/2/JCPSA6-98-2-1458-1.pd
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