A Pragmatic Evaluation of an Academic Practicum\u27s Knowledge Transfer Process

Practicums are designed to provide on-the-job learning experience for the students in their chosen occupational field. But do students actually benefit from practicums? This manuscript investigates linkages between knowledge repository systems and knowledge transfer in database technology practicums. It examines the literature on knowledge transfer, develops an Action Research methodology, and presents results of a new study in database academic practicums. The study focuses on a graduate school database technology practicum at Denver-based Regis University. As a member of an academic practicum team with responsibilities involving database administrative support to a group of students and faculty, the researcher seeks to bring some data to bear on the types of methodologies utilized by past and current practicum teams over a twenty month period. The results of this investigation and the conditions that must be enabled for a practicum to effectively transfer knowledge will be presented

Venus Atmosphere Profile from a Maximum Entropy Principle

The variational method with constraints recently developed by Verkley and Gerkema to describe maximum-entropy atmospheric profiles is generalized to ideal gases but with temperature-dependent specific heats. In so doing, an extended and non standard potential temperature is introduced that is well suited for tackling the problem under consideration. This new formalism is successfully applied to the atmosphere of Venus. Three well defined regions emerge in this atmosphere up to a height of $100 km$ from the surface: the lowest one up to about $35 km$ is adiabatic, a transition layer located at the height of the cloud deck and finally a third region which is practically isothermal.Comment: 6 pages, 3 figure

Neutrinos from Accreting Neutron Stars

The magnetospheres of accreting neutron stars develop electrostatic gaps with huge potential drops. Protons and ions, accelerated in these gaps along the dipolar magnetic field lines to energies greater than 100 TeV, can impact onto a surrounding accretion disc. A proton-induced cascade so develops, and $\nu$-emission is produced from charged pion decays. Using GEANT4, a computer code that tracks particles produced in high energy collisions, we have calculated the resulting $\nu$-spectrum with extensive disc shower simulations. We show that the $\nu$-spectrum produced out of the proton beam is a power law. We use this result to propose accretion-powered X-ray binaries (with highly magnetized neutron stars) as a new population of point-like $\nu$-sources for km-scale detectors, such as ICECUBE. As a particular example we discuss the case of A0535+26. We show that ICECUBE should find A0535+26 to be a periodic $\nu$-source: one for which the formation and loss of its accretion disc can be fully detected. Finally, we briefly comment on the possibility that smaller telescopes, like AMANDA, could also detect A0535+26 by folding observations with the orbital period.Comment: 7 pages, 5 figures. Updates to match accepted version in Astrophys.

OpenLab ESEV: novas aventuras no desenvolvimento de software

OpenLab ESEV is the Free Software project of the School of Education - Polytechnic Institute of Viseu (ESEV). The project aims to establish a platform to aggregate activities that foster the use of Free/Libre and Open Source Software (F/LOSS), Free Culture and more flexible licenses for creative and educational purposes in the ESEV's domains of activity (education, arts, media). OpenLab exists since 2009. It emerged in an environment characterized by the lack of knowledge of the existing Libre alternatives and by work habits exclusively built around proprietary software. Today, OpenLab activities are implemented within four key areas of action: dissemination, training, support and production. This paper presents two of the most important ongoing projects: Ottographer and StudiozCollabPress. StudiozCollabPress is a customized version of a popular WordPress plugin for project management that was developed to support short movie projects management. We'll present its main features and results from real-case scenarios of use, specifically, finished and ongoing 3D animation students' projects. Ottographer is a webcam time-lapse tool for operating systems based on Debian GNU/Linux. Besides the main features, we'll present some examples and suggestions for educational settings as well as for creative and educational purposes. Both projects are distributed as F/LOSS, meaning that they can be used, studied, and modified without restrictions, as well as copied and redistributed in modified or unmodified form. These projects might help us launch a new trend at our school community that we highly antecipate: the development and sharing of our own tools

Autoimmune neurological conditions associated with Zika virus infection

Zika virus (ZIKV) is an emerging flavivirus rapidly spreading throughout the tropical Americas. mosquitoes is the principal way of transmission of the virus to humans. ZIKV can be spread by transplacental, perinatal, and body fluids. ZIKV infection is often asymptomatic and those with symptoms present minor illness after 3 to 12 days of incubation, characterized by a mild and self-limiting disease with low-grade fever, conjunctivitis, widespread pruritic maculopapular rash, arthralgia and myalgia. ZIKV has been linked to a number of central and peripheral nervous system injuries such as Guillain-Barré syndrome (GBS), transverse myelitis (TM), meningoencephalitis, ophthalmological manifestations, and other neurological complications. Nevertheless, mechanisms of host-pathogen neuro-immune interactions remain incompletely elucidated. This review provides a critical discussion about the possible mechanisms underlying the development of autoimmune neurological conditions associated with Zika virus infection

Deficit of Kcnma1 mRNA expression in the dentate gyrus of epileptic rats

Epileptogenesis in mesial temporal lobe epilepsy is determined by several factors including abnormalities in the expression and function of ion channels. Here, we report a long-lasting deficit in gene expression of Kcnma1 coding for the large-conductance calcium-activated potassium (BK, MaxiK) channel α-subunits after pilocarpine-induced status epilepticus. By using comparative realtime PCR, Taqman gene expression assays, and the delta-delta comparative threshold method we detected a significant reduction in Kcnma1 expression in microdissected dentate gyrus at different intervals after status epilepticus (24 h, 10 days, 1 month, and more than 2 months). BK channels are key regulators of neuronal excitability and transmitter release. Hence, defective Kcnma1 expression may play a critical role in the pathogenesis of mesial temporal lobe epilepsy

Differential changes in mGlu2 and mGlu3 gene expression following pilocarpine-induced status epilepticus: A comparative real-time PCR analysis

Group II metabotropic glutamate (mGlu II) receptors subtype 2 and 3 (mGlu2 and mGlu3) are subtle regulators of neuronal excitability and synaptic plasticity in the hippocampus. In recent years, researchers have investigated the potential neuroprotective and anticonvulsant effects of compounds acting on mGlu II receptors. However, abnormal expression and function of mGlu2 and mGlu3 have been reported in temporal lobe epilepsy, a phenomena that may limit the therapeutic effectiveness of these potentially new antiepileptic drugs. Here, we investigated seizure-induced changes in mGlu2 and mGlu3 mRNA following pilocarpine-inducted status epilepticus (SE) and subsequent epileptogenesis. Relative changes in gene expression were assessed by comparative analysis of quantitative real-time PCR (qrtPCR) by the delta–delta CT method. Pilocarpine-treated and control rats were sacrificed at different periods (24 h, 10 days, one month and more than two months) following SE. Total RNA was isolated from microdissected dentate gyrus and processed for RT-PCR and qrtPCR using glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as an endogenous control gene. Analysis of relative quantification (RQ) ratios of mGlu2 and mGlu3 mRNA expression revealed a significant down-regulation of both targets at 24 h after SE. Gene expression partially recovered at 10 days following SE reaching control levels at one month after SE. Two month after SE, mGlu2 mRNA expression was significantly down-regulated to ~ 41% of control expression whereas mGlu3 mRNA was comparable to control levels. Our data indicate that mGlu2 and mGlu3 expression is dynamically down-regulated or selectively enhanced during critical periods of epileptogenesis. Seizure-induced differential dysregulation of mGlu2 and mGlu3 receptors may affect the availability of these molecular targets for therapeutic compounds in epilepsy

Deficit of Kcnma1 mRNA expression in the dentate gyrus of epileptic rats

Epileptogenesis in mesial temporal lobe epilepsy is determined by several factors including abnormalities in the expression and function of ion channels. Here, we report a long-lasting deficit in gene expression of Kcnma1 coding for the large-conductance calcium-activated potassium (BK, MaxiK) channel alpha-subunits after pilocarpine-induced status epilepticus. By using comparative real-time PCR, Taqman gene expression assays, and the delta-delta comparative threshold method we detected a significant reduction in Kcnma1 expression in microdissected dentate gyrus at different intervals after status epilepticus (24 h, 10 days, 1 month, and more than 2 months). BK channels are key regulators of neuronal excitability and transmitter release. Hence, defective Kcnma1 expression may play a critical role in the pathogenesis of mesial temporal lobe epilepsy

Hurst Coefficient in long time series of population size: Model for two plant populations with different reproductive strategies

Can the fractal dimension of fluctuations in population size be used to estimate extinction risk? The problem with estimating this fractal dimension is that the lengths of the time series are usually too short for conclusive results. This study answered this question with long time series data obtained from an iterative competition model. This model produces competitive extinction at different perturbation intensities for two different germination strategies: germination of all seeds vs. dormancy in half the seeds. This provided long time series of 900 years and different extinction risks. The results support the hypothesis for the effectiveness of the Hurst coefficient for estimating extinction risk

Multiple and Precessing Collimated Outflows in the Planetary Nebula IC 4634

With its remarkable double-S shape, IC 4634 is an archetype of point-symmetric planetary nebulae (PN). In this paper, we present a detailed study of this PN using archival HST WFPC2 and ground-based narrow-band images to investigate its morphology, and long-slit spectroscopic observations to determine its kinematics and to derive its physical conditions and excitation. The data reveal new structural components, including a distant string of knots distributed along an arc-like feature 40"-60" from the center of the nebula, a skin of enhanced [O III]/H-alpha ratio enveloping the inner shell and the double-S feature, and a triple-shell structure. The spatio-kinematical study also finds an equatorial component of the main nebula that is kinematically independent from the bright inner S-shaped arc. We have investigated in detail the bow shock-like features in IC 4634 and found that their morphological, kinematical and emission properties are consistent with the interaction of a collimated outflow with surrounding material. Indeed, the morphology and kinematics of some of these features can be interpreted using a 3D numerical simulation of a collimated outflow precessing at a moderate, time-dependent velocity. Apparently, IC 4634 has experienced several episodes of point-symmetric ejections oriented at different directions with the outer S-shaped feature being related to an earlier point-symmetric ejection and the outermost arc-like string of knots being the relic of an even much earlier point-symmetric ejection. There is tantalizing evidence that the action of these collimated outflows has also taken part in the shaping of the innermost shell and inner S-shaped arc of IC 4634.Comment: 16 pages, 11 figures, accepted for publication in The Astrophysical Journa