Can the Services Sector Be an Engine of Economic Growth for the Philippines?

With the services sector outpacing the Philippines' manufacturing sector in terms of growth and contribution to the country's gross domestic product (GDP) for decades now, is it prudent, as some quarters propose, for the government to "abandon" the manufacturing sector and shift its policy in support of the services sector as the engine of economic growth for the Philippines? This Policy Notes emphatically says "no" and highlights the arguments against such policy shift.services sector, manufacturing sector, deindustrialization

Shedding of host autophagic proteins from the parasitophorous vacuolar membrane of Plasmodium berghei

The hepatic stage of the malaria parasite Plasmodium is accompanied by an autophagy-mediated host response directly targeting the parasitophorous vacuolar membrane (PVM) harbouring the parasite. Removal of the PVM-associated autophagic proteins such as ubiquitin, p62, and LC3 correlates with parasite survival. Yet, it is unclear how Plasmodium avoids the deleterious effects of selective autophagy. Here we show that parasites trap host autophagic factors in the tubovesicular network (TVN), an expansion of the PVM into the host cytoplasm. In proliferating parasites, PVM-associated LC3 becomes immediately redirected into the TVN, where it accumulates distally from the parasite's replicative centre. Finally, the host factors are shed as vesicles into the host cytoplasm. This strategy may enable the parasite to balance the benefits of the enhanced host catabolic activity with the risk of being eliminated by the cell's cytosolic immune defence

Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing

Modern wound dressings combine medical textiles with active compounds that stimulate wound healing while protecting against infection. Electrospun wound dressings have been extensively studied and the electrospinning technique recognized as an efficient approach for the production of nanoscale fibrous mats. The unique diverse function and architecture of antimicrobial peptides (AMPs) has attracted considerable attention as a tool for the design of new anti-infective drugs. Functionalizing electrospun wound dressings with these AMPs is nowadays being researched. In the present work, we explore these new systems by highlighting the most important characteristics of electropsun wound dressings, revealing the importance of AMPs to wound healing, and the methods available to functionalize the electrospun mats with these molecules. The combined therapeutic potential of collagen type I and these AMP functionalized dressings will be highlighted as well; the significance of these new strategies for the future of wound healing will be clarified.FCT -Fuel Cell Technologies Program(POCI-01-0145-FEDER-007136)info:eu-repo/semantics/publishedVersio

Children's computation of complex linguistic forms: a study of frequency and imageability effects.

This study investigates the storage vs. composition of inflected forms in typically-developing children. Children aged 8-12 were tested on the production of regular and irregular past-tense forms. Storage (vs. composition) was examined by probing for past-tense frequency effects and imageability effects--both of which are diagnostic tests for storage--while controlling for a number of confounding factors. We also examined sex as a factor. Irregular inflected forms, which must depend on stored representations, always showed evidence of storage (frequency and/or imageability effects), not only across all children, but also separately in both sexes. In contrast, for regular forms, which could be either stored or composed, only girls showed evidence of storage. This pattern is similar to that found in previously-acquired adult data from the same task, with the notable exception that development affects which factors influence the storage of regulars in females: imageability plays a larger role in girls, and frequency in women. Overall, the results suggest that irregular inflected forms are always stored (in children and adults, and in both sexes), whereas regulars can be either composed or stored, with their storage a function of various item- and subject-level factors

Dynamics in the vicinity of (101955) Bennu: Solar radiation pressure effects in equatorial orbits

Here we study the dynamical effects of the solar radiation pressure (SRP) on a spacecraft that will survey the near-Earth rotating asteroid (101955) Bennu when the projected shadow is accounted for. The spacecraft's motion near (101955) Bennu is modelled in the rotating frame fixed at the centre of the asteroid, neglecting the sun gravity effects. We calculate the solar radiation pressure at the perihelion, semi-major axis and aphelion distances of the asteroid from the Sun. The goals of this work are to analyse the stability for both homogeneous and inhomogeneous mass distribution and study the effects of the solar radiation pressure in equatorial orbits close to the asteroid (101955) Bennu. As results, we find that the mascon model divided into ten equal layers seems to be the most suitable for this problem. We can highlight that the centre point $E$8, which was linearly stable in the case of the homogeneous mass distribution, becomes unstable in this new model changing its topological structure. For a Sun initial longitude $\psi_0 = -180^o$, starting with the spacecraft longitude $\lambda = 0$, the orbits suffer fewer impacts and some (between 0.4 and 0.5 km), remaining unwavering even if the maximum solar radiation is considered. When we change the initial longitude of the Sun to $\psi_0 = -135^o$, the orbits with initial longitude $\lambda = 90^0$ appear to be more stable. Finally, when the passage of the spacecraft in the shadow is accounted for, the effects of solar radiation pressure are softened, and we find more stable orbits.Comment: Accepted 2017 May 10. Received 2017 April 29; in original form 2017 January 1

On the random neighbor Olami-Feder-Christensen slip-stick model

We reconsider the treatment of Lise and Jensen (Phys. Rev. Lett. 76, 2326 (1996)) on the random neighbor Olami-Feder-Christensen stik-slip model, and examine the strong dependence of the results on the approximations used for the distribution of states p(E).Comment: 6pages, 3 figures. To be published in PRE as a brief repor

Adaptación al castellano y estructura factorial del Denison

6 pages, 4 tables[ES]En este estudio se presenta la adaptación al castellano del Denison Organizational Culture Survey, una encuesta diseñada para la evaluación de la cultura organizativa. Está compuesta por 60 ítems agrupados en 12 subescalas que identifican a su vez 4 dimensiones culturales, de aceptada influencia en la efectividad organizacional. La muestra consta de 488 personas y se ha utilizado análisis factorial confirmatorio. Los resultados obtenidos señalan unas propiedades psicométricas adecuadas, por lo que cabe concluir que la adaptación española replica casi en su totalidad la estructura planteada en la versión original.[EN]Spanish adaptation and factor structure of the Denison Organizational Culture Survey. This article presents a Spanish adaptation of the Denison Organizational Culture Survey, a questionnaire designed to evaluate organizational culture. This survey consists of 60 items, grouped in 12 subscales, which identify 4 cultural dimensions. These dimensions have been widely studied and their influence in organizational effectiveness has been accepted. This adaptation was applied to 488 participants, and analysed with confirmatory factor analysis. Results show adequate psychometric properties, so it can be concluded that the Spanish adaptation almost completely replicates the structure of the original version in English.Este trabajo se enmarca en un proyecto de investigación aprobado por el Ministerio de Educación y Ciencia titulado: «Influencia de la cultura organizativa y el flujo de conocimiento sobre el rendimiento científico de los grupos de I+D tecnológicos. Aplicación en la Universidad Politécnica de Valencia» (SEJ2005_08603).Peer reviewe