156 research outputs found
Motion cueing per simulatori dinamici di veicolo: algoritmi MPC basati su modelli percettivi
La tesi in questione realizza un sistema di motion cueing basato su Model Predictive Control, per un simulatore dinamico di guida automobilistica. Il modello su cui si esegue MPC comprende il sistema meccanico e quello vestibolare, quest'ultimo è stato scelto dopo un'attenta analisi di quanto esistente in letteratura. La strategia di controllo è stata ottimizzata con due importanti accorgimenti in vista di una sua implementazione reale: la decimazione e la generazione del riferimento. La prima consente di ottenere tempi di calcolo dell'ordine del real time, la seconda di fare predizione intelligente sulla base di telemetrie relative a giri precedentiopenMotivi di segretezza e/o di proprietà dei risultati e informazioni di enti esterni o aziende private che hanno partecipato alla realizzazione del lavoro di ricerca relativo alla tesi.
Motivi di priorità nella ricerca (previo accordo con terze parti
Performance analysis of a power transmission system under uncertain load conditions and network configurations
International audienceIn this paper, the load flow problem in a power transmission network is studied in presence of load and power generation uncertainties and transmission lines failures. Network performance indicators are computed and the importance of the different components is evaluated by a power flow betwenness centrality measure
Supporting the design of pilot learning activities with the Pedagogical Plan Manager
Pilot actions for introducing ICT-based innovation in school education generally involve a multitude of elements and a range of different actors. Accounting for and grasping this complexity calls for systematic pedagogical planning efforts that provide a solid basis for accommodating the different perspectives, for analysing the factors at play and also for casting light on the initial assumptions and theoretical framework adopted. These are the issues currently being addressed in a European project called ReMath, in which the authors are developing and testing a prototype ICT-based tool called the Pedagogical Plan Manager (PPM). The system supports the construction and sharing of pedagogical plans within a community of different actors operating in different contexts with different visions. This paper briefly describes some of the requirements that have shaped the PPM and outlines the conceptual model on which it is based. The system is described in the light of two vital characteristics it presents for the design of learning activities, namely expressiveness and flexibility
ROS in platelet biology: Functional aspects and methodological insights
© 2020 by the authors.
Reactive oxygen species (ROS) and mitochondria play a pivotal role in regulating platelet functions. Platelet activation determines a drastic change in redox balance and in platelet metabolism. Indeed, several signaling pathways have been demonstrated to induce ROS production by NAPDH oxidase (NOX) and mitochondria, upon platelet activation. Platelet-derived ROS, in turn, boost further ROS production and consequent platelet activation, adhesion and recruitment in an auto-amplifying loop. This vicious circle results in a platelet procoagulant phenotype and apoptosis, both accounting for the high thrombotic risk in oxidative stress-related diseases. This review sought to elucidate molecular mechanisms underlying ROS production upon platelet activation and the effects of an altered redox balance on platelet function, focusing on the main advances that have been made in platelet redox biology. Furthermore, given the increasing interest in this field, we also describe the up-to-date methods for detecting platelets, ROS and the platelet bioenergetic profile, which have been proposed as potential disease biomarkers
1128-124 Predictive validity of criteria for the epidemiological diagnosis of heart failure in the elderly: The icare dicomano study
Thoracic kyphosis and ventilatory dysfunction in unselected older persons: an epidemiological study in Dicomano, Italy.
Strategies for Engaging and Outreaching NEETs in Italy: Insights From Active Labour Policies
Outreaching and engaging young people who are not in education, employment, or training (i.e., NEETs) represents a significant challenge for public policies. They often belong to marginalized and disadvantaged categories and find themselves isolated with low levels of trust in the future, in their capacities of finding a job, and, above all, in institutions. Much research has emphasized how insufficient and unsuitable the strategies used so far have proved to be. However, there is a lack of clear mapping in the literature of what approaches have been suggested and addressed by the different guidelines. This study explores the strategies that a specific active labour policy uses to intercept and engage vulnerable youth and NEETs. This research employed a qualitative methodology that centres on the examination of official documents of the regional plans for the guaranteed employability of workers (Garanzia di Occupabilità dei Lavoratori). To conduct the analysis, the MAXQDA software package was utilized, and a content document analysis was implemented. Three main themes emerged from the analysis: capillarity of services, digitalization, and communication, each with its respective sub-themes. These themes provide valuable insights into the current strategies employed to engage vulnerable NEET youth, as well as other demographic categories, highlighting the potential strengths and weaknesses of these policies. The study holds the potential to contribute significantly to the development of more targeted and sustainable public policies, aiming to address the challenges faced by vulnerable NEET youth in Italy
Subtle neurological abnormalities as risk factors for cognitive and functional decline, cerebrovascular events, and mortality in older community-dwelling adults.
Prevalence and phenotype of the c.1529C>T SPG7 variant in adult-onset cerebellar ataxia in Italy
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