Confined Quantum Time of Arrival for Vanishing Potential

We give full account of our recent report in [E.A. Galapon, R. Caballar, R. Bahague {\it Phys. Rev. Let.} {\bf 93} 180406 (2004)] where it is shown that formulating the free quantum time of arrival problem in a segment of the real line suggests rephrasing the quantum time of arrival problem to finding a complete set of states that evolve to unitarily arrive at a given point at a definite time. For a spatially confined particle, here it is shown explicitly that the problem admits a solution in the form of an eigenvalue problem of a class of compact and self-adjoint time of arrival operators derived by a quantization of the classical time of arrival. The eigenfunctions of these operators are numerically demonstrated to unitarilly arrive at the origin at their respective eigenvalues.Comment: accepted for publication in Phys. Rev.

Structured aqueous processed lignin-based NMC cathodes for energy-dense LIBs with improved rate capability

The cost and environmental impact of lithium-ion batteries (LIBs) can be reduced substantially by enabling the aqueous processing of cathode materials. For the first time, we fabricate high-density, thick NMC111 cathode coatings using water as a solvent, and bio-derived kraft lignin as a binder material. The performance deterioration at high discharge currents is amplified by high mass loading and low bulk porosity. At porosities higher than 60%, the electronic conductivity limits the rate capability of the cathode, while for porosities lower than 30%, ionic conduction causes significant ionic polarization and consequently diminishes rate performance. The underlying lithium-ion diffusion limitation at current densities higher than 0.2 C is mitigated by creating line structures on the surface of the cathode. Structuring the half-dried cathode surface with ceramic blades is preferred over a stamp-like silicon wafer, and the line structures are easier to produce with high mechanical stability in comparison to pit structures. The lignin/water cells investigated herein restore after undergoing rate capability tests (5C), except those with pit structures or ultra-high thickness (>200 μm), due to the extensive crack formation during water evaporation which causes poor mechanical stability. Mechanical and laser structuring methods are compared on the surface of a PVDF/NMP-based cathode. Concerning the implementation in a large-scale battery factory, mechanical structuring is currently considered a processing of choice as it has no surface residuals or waste material. However, laser structuring with ultra-short pulses technique has the potential of outperforming mechanical structuring if the process is optimized to high precision to reduce residual and waste material, due to reproducibility and lower operational costs

The discrete fragmentation equations : semigroups, compactness and asynchronous exponential growth

In this paper we present a class of fragmentation semigroups which are compact in a scale of spaces defined in terms of finite higher moments. We use this compactness result to analyse the long time behaviour of such semigroups and, in particular, to prove that they have the asynchronous growth property. We note that, despite compactness, this growth property is not automatic as the fragmentation semigroups are not irreducible

The hidden burden of adult allergic rhinitis : UK healthcare resource utilisation survey

Funding Funding for this survey was provided by Meda Pharma.Peer reviewedPublisher PD

Inhomogeneous isospin distribution in the reactions of 28Si + 112Sn and 124Sn at 30 and 50 MeV/nucleon

We have created quasiprojectiles of varying isospin via peripheral reactions of 28Si + 112Sn and 124Sn at 30 and 50 MeV/nucleon. The quasiprojectiles have been reconstructed from completely isotopically identified fragments. The difference in N/Z of the reconstructed quasiprojectiles allows the investigation of the disassembly as a function of the isospin of the fragmenting system. The isobaric yield ratio 3H/3He depends strongly on N/Z ratio of quasiprojectiles. The dependences of mean fragment multiplicity and mean N/Z ratio of the fragments on N/Z ratio of the quasiprojectile are different for light charged particles and intermediate mass fragments. Observation of a different N/Z ratio of light charged particles and intermediate mass fragments is consistent with an inhomogeneous distribution of isospin in the fragmenting system.Comment: 5 pages, 4 Postscript figures, RevTe

Searching for Exoplanets Using a Microresonator Astrocomb

Detection of weak radial velocity shifts of host stars induced by orbiting planets is an important technique for discovering and characterizing planets beyond our solar system. Optical frequency combs enable calibration of stellar radial velocity shifts at levels required for detection of Earth analogs. A new chip-based device, the Kerr soliton microcomb, has properties ideal for ubiquitous application outside the lab and even in future space-borne instruments. Moreover, microcomb spectra are ideally suited for astronomical spectrograph calibration and eliminate filtering steps required by conventional mode-locked-laser frequency combs. Here, for the calibration of astronomical spectrographs, we demonstrate an atomic/molecular line-referenced, near-infrared soliton microcomb. Efforts to search for the known exoplanet HD 187123b were conducted at the Keck-II telescope as a first in-the-field demonstration of microcombs

Observational Constraints on the Angular and Spectral Distributions of Photons in Gamma-Ray Burst Sources

The typical spectra of gamma-ray bursts (GRBs) are discussed in the context of the compactness problem for GRB sources and how it is resolved in the popular fireball model. In particular, observational (model-independent) constraints on the collimation of the gamma-rays and the dependence of the collimation angle on the photon energy are considered. The fact that the threshold for the creation of $e^{-}e^{+}$ pairs depends on the angle between the momenta of the annihilating photons in the GRB source provides an alternative solution to the compactness problem. A new approach to explaining GRBs, taking into account the angular dependence for pair creation, is proposed, and the main features of a scenario describing a GRB source with a total (photon) energy smaller or of the order of $10^{49}$ erg are laid out. Thus, we are dealing with an alternative to an ultra-relativistic fireball, if it turns out (as follows from observations) that all "long" GRBs are associated with normal (not peculiar) core-collapse supernovae. The effects of radiation pressure and the formation of jets as a consequence of even a small amount of anisotropy in the total radiation field in a (compact) GRB source are examined in this alternative model. Possible energy release mechanisms acting in regions smaller or of the order of $10^{8}$ cm in size (a compact model for a GRB) are discussed. New observational evidence for such compact energy release in the burst source is considered.Comment: 15 pages, no figures, no table

Clinical mastitis in cows treated with sometribove (recombinant bovine somatotropin) and its relationship to milk yield.

Effect of sometribove (methionyl bovine somatotropin) on mastitis in 15 full lactation trials (914 cows) in Europe and the US and 70 short-term studies (2697 cows) in eight countries was investigated. In full lactation studies, sometribove (500 mg/2 wk) was given for 252 d, commencing 60 d postpartum. Although herds varied considerably, incidence of clinical mastitis within a herd was similar for cows receiving control and sometribove treatments. Relative risk analyses indicated no treatment effect, and percentage of mastitis during treatment was similar for control and sometribove groups. A positive linear relationship existed between peak milk yield and mastitis incidence (percentage of cows contracting mastitis or cases per 100 cow days); sometribove treatment did not alter this relationship. Increases in mastitis related to milk yield increase from sometribove or related to genetic selection were similar. When expressed per unit of milk, mastitis incidence declined slightly as milk yield increased; this relationship was not altered by sometribove. No effect on clinical mastitis was observed in 70 commercial herds utilizing sometribove for 84 d. However, effects were significant for stage of lactation and milk yield. Overall, studies represented a wide range of research and commercial situations demonstrating that sometribove had no effect on incidence of clinical mastitis during the lactation of treatment. Furthermore, sometribove did not alter typical relationships between milk yield or herd factors and incidence of clinical mastitis

Isospin Physics in Heavy-Ion Collisions at Intermediate Energies

In nuclear collisions induced by stable or radioactive neutron-rich nuclei a transient state of nuclear matter with an appreciable isospin asymmetry as well as thermal and compressional excitation can be created. This offers the possibility to study the properties of nuclear matter in the region between symmetric nuclear matter and pure neutron matter. In this review, we discuss recent theoretical studies of the equation of state of isospin-asymmetric nuclear matter and its relations to the properties of neutron stars and radioactive nuclei. Chemical and mechanical instabilities as well as the liquid-gas phase transition in asymmetric nuclear matter are investigated. The in-medium nucleon-nucleon cross sections at different isospin states are reviewed as they affect significantly the dynamics of heavy ion collisions induced by radioactive beams. We then discuss an isospin-dependent transport model, which includes different mean-field potentials and cross sections for the proton and neutron, and its application to these reactions. Furthermore, we review the comparisons between theoretical predictions and available experimental data. In particular, we discuss the study of nuclear stopping in terms of isospin equilibration, the dependence of nuclear collective flow and balance energy on the isospin-dependent nuclear equation of state and cross sections, the isospin dependence of total nuclear reaction cross sections, and the role of isospin in preequilibrium nucleon emissions and subthreshold pion production.Comment: 101 pages with embedded epsf figures, review article for "International Journal of Modern Physics E: Nuclear Physics". Send request for a hard copy to 1/author

Optimized high gradient magnetic separation for isolation of Plasmodium-infected red blood cells

<p>Abstract</p> <p>Background</p> <p>Highly purified infected red blood cells (irbc), or highly synchronized parasite cultures, are regularly required in malaria research. Conventional isolation and synchronization rely on density and osmotic fragility of irbc, respectively. High gradient magnetic separation (HGMS) offers an alternative based on intrinsic magnetic properties of irbc, avoiding exposure to chemicals and osmotic stress. Successful HGMS concentration in malaria research was previously reported using polymer coated columns, while HGMS depletion has not been described yet. This study presents a new approach to both HGMS concentration and depletion in malaria research, rendering polymer coating unnecessary.</p> <p>Methods</p> <p>A dipole magnet generating a strong homogenous field was custom assembled. Polypropylene syringes were fitted with one-way stopcocks and filled with stainless steel wool. Rbc from <it>Plasmodium falciparum </it>cultures were resuspended in density and viscosity optimized HGMS buffers and HGMS processed. Purification and depletion results were analysed by flow cytometer and light microscopy. Viability was evaluated by calculating the infection rate after re-culturing of isolates.</p> <p>Results</p> <p>In HGMS concentration, purity of irbc isolates from asynchronous cultures consistently ranged from 94.8% to 98.4% (mean 95.7%). With further optimization, over 90% of isolated irbc contained segmented schizonts. Processing time was less than 45 min. Reinfection rates ranged from 21.0% to 56.4%. In HGMS depletion, results were comparable to treatment with sorbitol, as demonstrated by essentially identical development of cultures.</p> <p>Conclusion</p> <p>The novel HGMS concentration procedure achieves high purities of segmented stage irbc from standard asynchronous cultures, and is the first HGMS depletion alternative to sorbitol lysis. It represents a simple and highly efficient alternative to conventional irbc concentration and synchronization methods.</p