3,810 research outputs found
High-harmonic generation: taking control of polarization
The ability to control the polarization of short-wavelength radiation generated by high-harmonic generation is useful not only for applications but also for testing conservation laws in physics
Physiological Indicators for User Trust in Machine Learning with Influence Enhanced Fact-Checking
© IFIP International Federation for Information Processing 2019. Trustworthy Machine Learning (ML) is one of significant challenges of âblack-boxâ ML for its wide impact on practical applications. This paper investigates the effects of presentation of influence of training data points on machine learning predictions to boost user trust. A framework of fact-checking for boosting user trust is proposed in a predictive decision making scenario to allow users to interactively check the training data points with different influences on the prediction by using parallel coordinates based visualization. This work also investigates the feasibility of physiological signals such as Galvanic Skin Response (GSR) and Blood Volume Pulse (BVP) as indicators for user trust in predictive decision making. A user study found that the presentation of influences of training data points significantly increases the user trust in predictions, but only for training data points with higher influence values under the high model performance condition, where users can justify their actions with more similar facts to the testing data point. The physiological signal analysis showed that GSR and BVP features correlate to user trust under different influence and model performance conditions. These findings suggest that physiological indicators can be integrated into the user interface of AI applications to automatically communicate user trust variations in predictive decision making
The HATNet and HATSouth Exoplanet Surveys
The Hungarian-made Automated Telescope Network (HATNet) has been in operation
since 2003, with the key science goal being the discovery and accurate
characterization of transiting extrasolar planets (TEPs) around bright stars.
Using six small, 11\,cm\ aperture, fully automated telescopes in Arizona and
Hawaii, as of 2017 March, it has discovered and accurately characterized 67
such objects. The HATSouth network of telescopes has been in operation since
2009, using slightly larger, 18\,cm diameter optical tubes. It was the first
global network of telescopes using identical instrumentation. With three
premier sites spread out in longitude (Chile, Namibia, Australia), the HATSouth
network permits round-the-clock observations of a 128 square arcdegree swath of
the sky at any given time, weather permitting. As of this writing, HATSouth has
discovered 36 transiting exoplanets. Many of the altogether ~100 HAT and
HATSouth exoplanets were the first of their kind. They have been important
contributors to the rapidly developing field of exoplanets, motivating and
influencing observational techniques, theoretical studies, and also actively
shaping future instrumentation for the detection and characterization of such
objects.Comment: Invited review chapter, accepted for publication in "Handbook of
Exoplanets", edited by H.J. Deeg and J.A. Belmonte, Springer Reference Work
Ecological equivalence: a realistic assumption for niche theory as a testable alternative to neutral theory
Hubbell's 2001 neutral theory unifies biodiversity and biogeography by modelling steady-state distributions of species richness and abundances across spatio-temporal scales. Accurate predictions have issued from its core premise that all species have identical vital rates. Yet no ecologist believes that species are identical in reality. Here I explain this paradox in terms of the ecological equivalence that species must achieve at their coexistence equilibrium, defined by zero net fitness for all regardless of intrinsic differences between them. I show that the distinction of realised from intrinsic vital rates is crucial to evaluating community resilience. An analysis of competitive interactions reveals how zero-sum patterns of abundance emerge for species with contrasting life-history traits as for identical species. I develop a stochastic model to simulate community assembly from a random drift of invasions sustaining the dynamics of recruitment following deaths and extinctions. Species are allocated identical intrinsic vital rates for neutral dynamics, or random intrinsic vital rates and competitive abilities for niche dynamics either on a continuous scale or between dominant-fugitive extremes. Resulting communities have steady-state distributions of the same type for more or less extremely differentiated species as for identical species. All produce negatively skewed log-normal distributions of species abundance, zero-sum relationships of total abundance to area, and Arrhenius relationships of species to area. Intrinsically identical species nevertheless support fewer total individuals, because their densities impact as strongly on each other as on themselves. Truly neutral communities have measurably lower abundance/area and higher species/abundance ratios. Neutral scenarios can be parameterized as null hypotheses for testing competitive release, which is a sure signal of niche dynamics. Ignoring the true strength of interactions between and within species risks a substantial misrepresentation of community resilience to habitat los
Clinical malaria case definition and malaria attributable fraction in the highlands of western Kenya
BACKGROUND: In African highland areas where endemicity of malaria varies greatly according to altitude and topography, parasitaemia accompanied by fever may not be sufficient to define an episode of clinical malaria in endemic areas. To evaluate the effectiveness of malaria interventions, age-specific case definitions of clinical malaria needs to be determined. Cases of clinical malaria through active case surveillance were quantified in a highland area in Kenya and defined clinical malaria for different age groups. METHODS: A cohort of over 1,800 participants from all age groups was selected randomly from over 350 houses in 10 villages stratified by topography and followed for two-and-a-half years. Participants were visited every two weeks and screened for clinical malaria, defined as an individual with malaria-related symptoms (fever [axillary temperatureââ„â37.5°C], chills, severe malaise, headache or vomiting) at the time of examination or 1â2 days prior to the examination in the presence of a Plasmodium falciparum positive blood smear. Individuals in the same cohort were screened for asymptomatic malaria infection during the low and high malaria transmission seasons. Parasite densities and temperature were used to define clinical malaria by age in the population. The proportion of fevers attributable to malaria was calculated using logistic regression models. RESULTS: Incidence of clinical malaria was highest in valley bottom population (5.0% cases per 1,000 population per year) compared to mid-hill (2.2% cases per 1,000 population per year) and up-hill (1.1% cases per 1,000 population per year) populations. The optimum cut-off parasite densities through the determination of the sensitivity and specificity showed that in children less than five years of age, 500 parasites per ÎŒl of blood could be used to define the malaria attributable fever cases for this age group. In children between the ages of 5â14, a parasite density of 1,000 parasites per ÎŒl of blood could be used to define the malaria attributable fever cases. For individuals older than 14 years, the cut-off parasite density was 3,000 parasites per ÎŒl of blood. CONCLUSION: Clinical malaria case definitions are affected by age and endemicity, which needs to be taken into consideration during evaluation of interventions
Internet of things
Manual of Digital Earth / Editors: Huadong Guo, Michael F. Goodchild, Alessandro Annoni .- Springer, 2020 .- ISBN: 978-981-32-9915-3Digital Earth was born with the aim of replicating the real world within the digital world. Many efforts have been made to observe and sense the Earth, both from space (remote sensing) and by using in situ sensors. Focusing on the latter, advances in Digital Earth have established vital bridges to exploit these sensors and their networks by taking location as a key element. The current era of connectivity envisions that everything is connected to everything. The concept of the Internet of Things(IoT)emergedasaholisticproposaltoenableanecosystemofvaried,heterogeneous networked objects and devices to speak to and interact with each other. To make the IoT ecosystem a reality, it is necessary to understand the electronic components, communication protocols, real-time analysis techniques, and the location of the objects and devices. The IoT ecosystem and the Digital Earth (DE) jointly form interrelated infrastructures for addressing todayâs pressing issues and complex challenges. In this chapter, we explore the synergies and frictions in establishing an efïŹcient and permanent collaboration between the two infrastructures, in order to adequately address multidisciplinary and increasingly complex real-world problems. Although there are still some pending issues, the identiïŹed synergies generate optimism for a true collaboration between the Internet of Things and the Digital Earth
Intravenous leiomyomatosis of the uterus with extension to the right heart
A 42-year-old woman admitted with debilitation and engorgement both lower extremities. Transthoracic two-dimensional echocardiography, abdominal ultrasound and computerized tomography revealed a lobulated pelvic mass, a mass within right internal iliac vein, both common iliac vein, as well as the inferior vena cava, extending into the right atrium. In addition, echocardiography and abdominal ultrasound showed the tumor of right atrium and inferior vena cave has no stalk and has well-demarcated borders with the wall of right atrium and inferior vena cave. Hence, the presumptive diagnosis of IVL was made by echocardiography and abdominal ultrasound and the presumptive diagnosis of sarcoma with invasion in right internal iliac vein, both common iliac vein, the inferior vena cava, as well as the right atrium was made by multi-detector-row computerized tomography. The patient underwent a one-stage combined multidisciplinary thoraco-abdominal operation under general anaesthetic. Subsequently the pathologic report confirmed IVL
Strings on Semisymmetric Superspaces
Several string backgrounds which arise in the AdS/CFT correspondence are
described by integrable sigma-models. Their target space is always a Z(4)
supercoset (a semi-symmetric superspace). Here we list all semi-symmetric
cosets which have zero beta function and central charge c<=26 at one loop in
perturbation theory.Comment: 25 pages, 1 figur
Microguards and micromessengers of the genome
The regulation of gene expression is of fundamental importance to maintain organismal function and integrity and requires a multifaceted and highly ordered sequence of events. The cyclic nature of gene expression is known as âtranscription dynamicsâ. Disruption or perturbation of these dynamics can result in significant fitness costs arising from genome instability, accelerated ageing and disease. We review recent research that supports the idea that an important new role for small RNAs, particularly microRNAs (miRNAs), is in protecting the genome against short-term transcriptional fluctuations, in a process we term âmicroguardingâ. An additional emerging role for miRNAs is as âmicromessengersââthrough alteration of gene expression in target cells to which they are trafficked within microvesicles. We describe the scant but emerging evidence that miRNAs can be moved between different cells, individuals and even species, to exert biologically significant responses. With these two new roles, miRNAs have the potential to protect against deleterious gene expression variation from perturbation and to themselves perturb the expression of genes in target cells. These interactions between cells will frequently be subject to conflicts of interest when they occur between unrelated cells that lack a coincidence of fitness interests. Hence, there is the potential for miRNAs to represent both a means to resolve conflicts of interest, as well as instigate them. We conclude by exploring this conflict hypothesis, by describing some of the initial evidence consistent with it and proposing new ideas for future research into this exciting topic
Seasonal variations in carbon, nitrogen and phosphorus concentrations and C:N:P stoichiometry in different organs of a Larix principis-rupprechtii Mayr. plantation in the Qinling Mountains, China
Understanding how concentrations of elements and their stoichiometry change with plant growth and age is critical for predicting plant community responses to environmental change. Weusedlong-term field experiments to explore how the leaf, stem and root carbon (C), nitrogen (N) and phosphorous (P) concentrations and their stoichiometry changed with growth and stand age in a L.principis-rupprechtii Mayr. plantation from 2012â2015 in the Qinling Mountains, China. Our results showed that the C, N and P concentrations and stoichiometric ratios in different tissues of larch stands were affected by stand age, organ type andsampling month and displayed multiple correlations with increased stand age in different growing seasons. Generally, leaf C and N concentrations were greatest in the fast-growing season, but leaf P concentrations were greatest in the early growing season. However, no clear seasonal tendencies in the stem and root C, N and P concentrations were observed with growth. In contrast to N and P, few differences were found in organ-specific C concentrations. Leaf N:P was greatest in the fast-growing season, while C:N and C:P were greatest in the late-growing season. No clear variations were observed in stem and root C:N, C:P andN:Pthroughout the entire growing season, but leaf N:P was less than 14, suggesting that the growth of larch stands was limited by N in our study region. Compared to global plant element concentrations and stoichiometry, the leaves of larch stands had higher C, P, C:NandC:PbutlowerNandN:P,andtherootshadgreater PandC:NbutlowerN,C:Pand N:P. Our study provides baseline information for describing the changes in nutritional elements with plant growth, which will facilitates plantation forest management and restoration, and makes avaluable contribution to the global data pool on leaf nutrition and stoichiometry
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