Group Leaders Optimization Algorithm

We present a new global optimization algorithm in which the influence of the leaders in social groups is used as an inspiration for the evolutionary technique which is designed into a group architecture. To demonstrate the efficiency of the method, a standard suite of single and multidimensional optimization functions along with the energies and the geometric structures of Lennard-Jones clusters are given as well as the application of the algorithm on quantum circuit design problems. We show that as an improvement over previous methods, the algorithm scales as N^2.5 for the Lennard-Jones clusters of N-particles. In addition, an efficient circuit design is shown for two qubit Grover search algorithm which is a quantum algorithm providing quadratic speed-up over the classical counterpart

Prioritized Sweeping Neural DynaQ with Multiple Predecessors, and Hippocampal Replays

During sleep and awake rest, the hippocampus replays sequences of place cells that have been activated during prior experiences. These have been interpreted as a memory consolidation process, but recent results suggest a possible interpretation in terms of reinforcement learning. The Dyna reinforcement learning algorithms use off-line replays to improve learning. Under limited replay budget, a prioritized sweeping approach, which requires a model of the transitions to the predecessors, can be used to improve performance. We investigate whether such algorithms can explain the experimentally observed replays. We propose a neural network version of prioritized sweeping Q-learning, for which we developed a growing multiple expert algorithm, able to cope with multiple predecessors. The resulting architecture is able to improve the learning of simulated agents confronted to a navigation task. We predict that, in animals, learning the world model should occur during rest periods, and that the corresponding replays should be shuffled.Comment: Living Machines 2018 (Paris, France

Role of personality characteristics and sexual orientation in the risk for sexual addiction among Israeli men: validation of a Hebrew sex addiction scale

Men having sex with men are known to exhibit heightened sexual activity. This raises the conjecture that different sexual orientations exhibit different levels of sex addiction risk, which is also affected by personality. The present study examined the prevalence of the sex addiction risk within the context of sexual orientation and personality in Israeli men while also validating the Hebrew Bergen-Yale Sex Addiction Scale (HBYSAS). Results based on 177 participants showed that the HBYSAS is appropriate for assessing the risk for sex addiction in Israeli men. Furthermore, results showed that sex addiction risk varied with individuals’ sexual orientation while being modestly associated with higher neuroticism and lower conscientiousness

Mesoscopic rings with Spin-Orbit interactions

A didactic description of charge and spin equilibrium currents on mesoscopic rings in the presence of Spin-Orbit interaction is presented. Emphasis is made on the non trivial construction of the correct Hamiltonian in polar coordinates, the calculation of eigenvalues and eigenfunctions and the symmetries of the ground state properties. Spin currents are derived following an intuitive definition and then a more thorough derivation is built upon the canonical Lagrangian formulation that emphasizes the SU(2) gauge structure of the transport problem of spin 1/2 fermions in spin-orbit active media. The quantization conditions that follow from the constraint of single-valued Pauli spinors are also discussed. The targeted students are those of a graduate Condensed Matter Physics course

Non-factorizable Contributions to B→ππB \to \pi\pi Decays

We investigate to what extent the experimental information on $B \to \pi\pi$ branching fractions and CP asymmetries can be used to better understand the QCD dynamics in these decays. For this purpose we decompose the independent isospin amplitudes into factorizable and non-factorizable contributions. The former can be estimated within the framework of QCD factorization for exclusive $B$ decays. The latter vanish in the heavy-quark limit, $m_b \to \infty$, and are treated as unknown hadronic parameters. We discuss at some length in which way the non-factorizable contributions are treated in different theoretical and phenomenological frameworks. We point out the potential differences between the phenomenological treatment of power-corrections in the ``BBNS approach'', and the appearance of power -suppressed operators in soft-collinear effective theory (SCET). On that basis we define a handful of different (but generic) scenarios where the non-factorizable part of isospin amplitudes is parametrized in terms of three or four unknowns, which can be constrained by data. We also give some short discussion on the implications of our analysis for $B \to \pi K$ decays. In particular, since non-factorizable QCD effects in $B \to \pi \pi$ may be large, we cannot exclude sizeable non-factorizable effects, which violate $SU(3)_F$ flavour symmetry, or even isospin symmetry (via long-distance QED effects). This may help to explain certain puzzles in connection with isospin-violating observables in $B \to \pi K$ decays.Comment: published version, minor correction

Stochastic Invariants for Probabilistic Termination

Termination is one of the basic liveness properties, and we study the termination problem for probabilistic programs with real-valued variables. Previous works focused on the qualitative problem that asks whether an input program terminates with probability~1 (almost-sure termination). A powerful approach for this qualitative problem is the notion of ranking supermartingales with respect to a given set of invariants. The quantitative problem (probabilistic termination) asks for bounds on the termination probability. A fundamental and conceptual drawback of the existing approaches to address probabilistic termination is that even though the supermartingales consider the probabilistic behavior of the programs, the invariants are obtained completely ignoring the probabilistic aspect. In this work we address the probabilistic termination problem for linear-arithmetic probabilistic programs with nondeterminism. We define the notion of {\em stochastic invariants}, which are constraints along with a probability bound that the constraints hold. We introduce a concept of {\em repulsing supermartingales}. First, we show that repulsing supermartingales can be used to obtain bounds on the probability of the stochastic invariants. Second, we show the effectiveness of repulsing supermartingales in the following three ways: (1)~With a combination of ranking and repulsing supermartingales we can compute lower bounds on the probability of termination; (2)~repulsing supermartingales provide witnesses for refutation of almost-sure termination; and (3)~with a combination of ranking and repulsing supermartingales we can establish persistence properties of probabilistic programs. We also present results on related computational problems and an experimental evaluation of our approach on academic examples.Comment: Full version of a paper published at POPL 2017. 20 page

Optimally combining dynamical decoupling and quantum error correction

We show how dynamical decoupling (DD) and quantum error correction (QEC) can be optimally combined in the setting of fault tolerant quantum computing. To this end we identify the optimal generator set of DD sequences designed to protect quantum information encoded into stabilizer subspace or subsystem codes. This generator set, comprising the stabilizers and logical operators of the code, minimizes a natural cost function associated with the length of DD sequences. We prove that with the optimal generator set the restrictive local-bath assumption used in earlier work on hybrid DD-QEC schemes, can be significantly relaxed, thus bringing hybrid DD-QEC schemes, and their potentially considerable advantages, closer to realization.Comment: 6 pages, 1 figur

Epigenetics as a mechanism driving polygenic clinical drug resistance

Aberrant methylation of CpG islands located at or near gene promoters is associated with inactivation of gene expression during tumour development. It is increasingly recognised that such epimutations may occur at a much higher frequency than gene mutation and therefore have a greater impact on selection of subpopulations of cells during tumour progression or acquisition of resistance to anticancer drugs. Although laboratory-based models of acquired resistance to anticancer agents tend to focus on specific genes or biochemical pathways, such 'one gene : one outcome' models may be an oversimplification of acquired resistance to treatment of cancer patients. Instead, clinical drug resistance may be due to changes in expression of a large number of genes that have a cumulative impact on chemosensitivity. Aberrant CpG island methylation of multiple genes occurring in a nonrandom manner during tumour development and during the acquisition of drug resistance provides a mechanism whereby expression of multiple genes could be affected simultaneously resulting in polygenic clinical drug resistance. If simultaneous epigenetic regulation of multiple genes is indeed a major driving force behind acquired resistance of patients' tumour to anticancer agents, this has important implications for biomarker studies of clinical outcome following chemotherapy and for clinical approaches designed to circumvent or modulate drug resistance

Initial Time Singularities in Non-Equilibrium Evolution of Condensates and Their Resolution in the Linearized Approximation

The real time non-equilibrium evolution of condensates in field theory requires an initial value problem specifying an initial quantum state or density matrix. Arbitrary specifications of the initial quantum state (pure or mixed) results in initial time singularities which are not removed by the usual renormalization counterterms. We study the initial time singularities in the linearized equation of motion for the scalar condensate in a renormalizable Yukawa theory in 3+1 dimensions. In this renormalizable theory the initial time singularities are enhanced. We present a consistent method for removing these initial time singularities by specifying initial states where the distribution of high energy quanta is determined by the initial conditions and the interaction effects. This is done through a Bogoliubov transformation which is consistently obtained in a perturbative expansion.The usual renormalization counterterms and the proper choice of the Bogoliubov coefficients lead to a singularity free evolution equation. We establish the relationship between the evolution equations in the linearized approximation and linear response theory. It is found that only a very specific form of the external source for linear response leads to a real time evolution equation which is singularity free. We focus on the evolution of spatially inhomogeneous scalar condensates by implementing the initial state preparation via a Bogoliubov transformation up to one-loop. As a concrete application, the evolution equation for an inhomogenous condensate is solved analytically and the results are carefully analyzed. Symmetry breaking by initial quantum states is discussed.Comment: LaTex, 26 pages, 2 .ps figure

Ultraviolet through Infrared Spectral Energy Distributions from 1000 SDSS Galaxies: Dust Attenuation

The meaningful comparison of models of galaxy evolution to observations is critically dependent on the accurate treatment of dust attenuation. To investigate dust absorption and emission in galaxies we have assembled a sample of ~1000 galaxies with ultraviolet (UV) through infrared (IR) photometry from GALEX, SDSS, and Spitzer and optical spectroscopy from SDSS. The ratio of IR to UV emission (IRX) is used to constrain the dust attenuation in galaxies. We use the 4000A break as a robust and useful, although coarse, indicator of star formation history (SFH). We examine the relationship between IRX and the UV spectral slope (a common attenuation indicator at high-redshift) and find little dependence of the scatter on 4000A break strength. We construct average UV through far-IR spectral energy distributions (SEDs) for different ranges of IRX, 4000A break strength, and stellar mass (M_*) to show the variation of the entire SED with these parameters. When binned simultaneously by IRX, 4000A break strength, and M_* these SEDs allow us to determine a low resolution average attenuation curve for different ranges of M_*. The attenuation curves thus derived are consistent with a lambda^{-0.7} attenuation law, and we find no significant variations with M_*. Finally, we show the relationship between IRX and the global stellar mass surface density and gas-phase-metallicity. Among star forming galaxies we find a strong correlation between IRX and stellar mass surface density, even at constant metallicity, a result that is closely linked to the well-known correlation between IRX and star-formation rate.Comment: 12 pages, 8 figures, 2 tables, appearing in the Dec 2007 GALEX special issue of ApJ Supp (29 papers