210 research outputs found
Preliminary study of Augmented Reality based manufacturing for further integration of Quality Control 4.0 supported by metrology
Augmented Reality (AR) is a key technology enabling Industry 4.0, which enriches human perspectives by overlaying digital information onto the real world. The maturity of AR technology has grown recently. As processes in the automotive and aeronautic sectors require high quality and near-zero error rates to ensure the safety of end-users, AR can be implemented to facilitate workers with immersive interfaces to enhance productivity, accuracy and autonomy in the quality sector. In order to analyse whether there is a real and growing interest in the use of AR as assisting technology for manufacturing sector in general and quality control in particular, two specific research questions are defined. In addition, two well-known research databases (Scopus, Web of Science) are used for the paper selection phase in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology to conduct a preliminary study and evaluate the current development of AR applications in manufacturing sector in order to answer the defined questions. It is found that while the development of AR technology has widely implemented to assign real-time information to several systems and processes in assembly and maintenance sectors, this tendency has only emerged in the quality sector over the last few years. However, AR-based quality control has proved its advantages in improving productivity, accuracy and precision of operators as well as benefits to manufacturing in terms of product and process quality control across different manufacturing phases
Mean curvature flow in a Ricci flow background
Following work of Ecker, we consider a weighted Gibbons-Hawking-York
functional on a Riemannian manifold-with-boundary. We compute its variational
properties and its time derivative under Perelman's modified Ricci flow. The
answer has a boundary term which involves an extension of Hamilton's Harnack
expression for the mean curvature flow in Euclidean space. We also derive the
evolution equations for the second fundamental form and the mean curvature,
under a mean curvature flow in a Ricci flow background. In the case of a
gradient Ricci soliton background, we discuss mean curvature solitons and
Huisken monotonicity.Comment: final versio
Exactly solvable path integral for open cavities in terms of quasinormal modes
We evaluate the finite-temperature Euclidean phase-space path integral for
the generating functional of a scalar field inside a leaky cavity. Provided the
source is confined to the cavity, one can first of all integrate out the fields
on the outside to obtain an effective action for the cavity alone.
Subsequently, one uses an expansion of the cavity field in terms of its
quasinormal modes (QNMs)-the exact, exponentially damped eigenstates of the
classical evolution operator, which previously have been shown to be complete
for a large class of models. Dissipation causes the effective cavity action to
be nondiagonal in the QNM basis. The inversion of this action matrix inherent
in the Gaussian path integral to obtain the generating functional is therefore
nontrivial, but can be accomplished by invoking a novel QNM sum rule. The
results are consistent with those obtained previously using canonical
quantization.Comment: REVTeX, 26 pages, submitted to Phys. Rev.
Extreme Active Molecular Jets in L1448C
The protostellar jet driven by L1448C was observed in the SiO J=8-7 and CO
J=3-2 lines and 350 GHz dust continuum at ~1" resolution with the Submillimeter
Array (SMA). A narrow jet from the northern source L1448C(N) was observed in
the SiO and the high-velocity CO. The jet consists of a chain of emission knots
with an inter-knot spacing of ~2" (500 AU) and a semi-periodic velocity
variation. The innermost pair of knots, which are significant in the SiO map
but barely seen in the CO, are located at ~1" (250 AU) from the central source,
L1448C(N). Since the dynamical time scale for the innermost pair is only ~10
yr, SiO may have been formed in the protostellar wind through the gas-phase
reaction, or been formed on the dust grain and directly released into the gas
phase by means of shocks. It is found that the jet is extremely active with a
mechanical luminosity of ~7 L_sun, which is comparable to the bolometric
luminosity of the central source (7.5 L_sun). The mass accretion rate onto the
protostar derived from the mass-loss rate is ~10^{-5} M_sun/yr. Such a high
mass accretion rate suggests that the mass and the age of the central star are
0.03-0.09 M_sun and (4-12)x10^3 yr, respectively, implying that the central
star is in the very early stage of protostellar evolution. The low-velocity CO
emission delineates two V-shaped shells with a common apex at L1448C(N). The
kinematics of these shells are reproduced by the model of a wide opening angle
wind. The co-existence of the highly-collimated jets and the wide-opening angle
shells can be explained by the unified X-wind model" in which highly-collimated
jet components correspond to the on-axis density enhancement of the
wide-opening angle wind. The CO =3--2 map also revealed the second outflow
driven by the southern source L1448C(S) located at ~8.3" (2000 AU) from
L1448C(N).Comment: 45 pages, 13 figures, Accepted for the publication in the
Astrophysical Journa
Active Galaxies in the UV
In this article we present different aspects of AGN studies demonstrating the
importance of the UV spectral range. Most important diagnostic lines for
studying the general physical conditions as well as the metalicities in the
central broad line region in AGN are emitted in the UV. The UV/FUV continuum in
AGN excites not only the emission lines in the immediate surrounding but it is
responsible for the ionization of the intergalactic medium in the early stages
of the universe. Variability studies of the emission line profiles of AGN in
the UV give us information on the structure and kinematics of the immediate
surrounding of the central supermassive black hole as well as on its mass
itself.Comment: 29 pages, 13 figures, Ap&SS in pres
3D Studies of Neutral and Ionised Gas and Stars in Seyfert and Inactive Galaxies
We are conducting the first systematic 3D spectroscopic imaging survey to
quantify the properties of the atomic gas (HI) in a distance-limited sample of
28 Seyfert galaxies and a sample of 28 inactive control galaxies with
well-matched optical properties (the VHIKINGS survey). This study aims to
address the role of the host galaxy in nuclear activity and confront
outstanding controversies in optical/IR imaging surveys. Early results show
possible relationships between Seyfert activity and HI extent, content and the
prevalence of small, nearby gas-rich dwarf galaxies (M(HI)~10^7 Msun); results
will be tested via rigorous comparison with control galaxies. Initial results
from our optical followup study of 15 of our galaxies using the SAURON integral
field unit on the WHT suggest a possible difference between Seyfert and
inactive stellar and gaseous kinematics that support the conclusion that
internal kinematics of galaxies are the key to nuclear activity.Comment: 6 pages to be published in the proceedings of "The Fate of Gas in
Galaxies", held in Dwingeloo, July 200
Collapsing bubble in metal for high energy density physics study
This paper presents a new idea to produce matter in the high energy density physics (HEDP) regime in the laboratory using an intense ion beam. A gas bubble created inside a solid metal may collapse by driving it with an intense ion beam. The melted metal will compress the gas bubble and supply extra energy to it. Simulations show that the spherical implosion ratio can be about 5 and at the stagnation point, the maximum density, temperature and pressure inside the gas bubble can go up to nearly 2 times solid density, 10 eV and a few megabar (Mbar) respectively. The proposed experiment is the first to permit access into the Mbar regime with existing or near-term ion facilities, and opens up possibilities for new physics gained through careful comparisons of simulations with measurements of quantities like stagnation radius, peak temperature and peak pressure at the metal wall
The genetic architecture of the human cerebral cortex
INTRODUCTION
The cerebral cortex underlies our complex cognitive capabilities. Variations in human cortical surface area and thickness are associated with neurological, psychological, and behavioral traits and can be measured in vivo by magnetic resonance imaging (MRI). Studies in model organisms have identified genes that influence cortical structure, but little is known about common genetic variants that affect human cortical structure.
RATIONALE
To identify genetic variants associated with human cortical structure at both global and regional levels, we conducted a genome-wide association meta-analysis of brain MRI data from 51,665 individuals across 60 cohorts. We analyzed the surface area and average thickness of the whole cortex and 34 cortical regions with known functional specializations.
RESULTS
We identified 306 nominally genome-wide significant loci (P < 5 × 10−8) associated with cortical structure in a discovery sample of 33,992 participants of European ancestry. Of the 299 loci for which replication data were available, 241 loci influencing surface area and 14 influencing thickness remained significant after replication, with 199 loci passing multiple testing correction (P < 8.3 × 10−10; 187 influencing surface area and 12 influencing thickness).
Common genetic variants explained 34% (SE = 3%) of the variation in total surface area and 26% (SE = 2%) in average thickness; surface area and thickness showed a negative genetic correlation (rG = −0.32, SE = 0.05, P = 6.5 × 10−12), which suggests that genetic influences have opposing effects on surface area and thickness. Bioinformatic analyses showed that total surface area is influenced by genetic variants that alter gene regulatory activity in neural progenitor cells during fetal development. By contrast, average thickness is influenced by active regulatory elements in adult brain samples, which may reflect processes that occur after mid-fetal development, such as myelination, branching, or pruning. When considered together, these results support the radial unit hypothesis that different developmental mechanisms promote surface area expansion and increases in thickness.
To identify specific genetic influences on individual cortical regions, we controlled for global measures (total surface area or average thickness) in the regional analyses. After multiple testing correction, we identified 175 loci that influence regional surface area and 10 that influence regional thickness. Loci that affect regional surface area cluster near genes involved in the Wnt signaling pathway, which is known to influence areal identity.
We observed significant positive genetic correlations and evidence of bidirectional causation of total surface area with both general cognitive functioning and educational attainment. We found additional positive genetic correlations between total surface area and Parkinson’s disease but did not find evidence of causation. Negative genetic correlations were evident between total surface area and insomnia, attention deficit hyperactivity disorder, depressive symptoms, major depressive disorder, and neuroticism.
CONCLUSION
This large-scale collaborative work enhances our understanding of the genetic architecture of the human cerebral cortex and its regional patterning. The highly polygenic architecture of the cortex suggests that distinct genes are involved in the development of specific cortical areas. Moreover, we find evidence that brain structure is a key phenotype along the causal pathway that leads from genetic variation to differences in general cognitive function
Novel genetic loci associated with hippocampal volume
The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (rg =-0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness
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