23 research outputs found
On The Mobile Behavior of Solid He at High Temperatures
We report studies of solid helium contained inside a torsional oscillator, at
temperatures between 1.07K and 1.87K. We grew single crystals inside the
oscillator using commercially pure He and He-He mixtures containing
100 ppm He. Crystals were grown at constant temperature and pressure on the
melting curve. At the end of the growth, the crystals were disordered,
following which they partially decoupled from the oscillator. The fraction of
the decoupled He mass was temperature and velocity dependent. Around 1K, the
decoupled mass fraction for crystals grown from the mixture reached a limiting
value of around 35%. In the case of crystals grown using commercially pure
He at temperatures below 1.3K, this fraction was much smaller. This
difference could possibly be associated with the roughening transition at the
solid-liquid interface.Comment: 15 pages, 6 figure
Velocity-force characteristics of an interface driven through a periodic potential
We study the creep dynamics of a two-dimensional interface driven through a
periodic potential using dynamical renormalization group methods. We find that
the nature of weak-drive transport depends qualitatively on whether the
temperature is above or below the equilibrium roughening transition
temperature . Above , the velocity-force characteristics is Ohmic,
with linear mobility exhibiting a jump discontinuity across the transition. For
, the transport is highly nonlinear, exhibiting an interesting
crossover in temperature and weak external force . For intermediate drive,
, we find near a power-law velocity-force characteristics
, with , and well-below ,
, with . In the limit
of vanishing drive () the velocity-force characteristics crosses over
to , and is controlled by soliton nucleation.Comment: 18 pages, submitted to Phys. Rev.
Dependence of the emission from tris(8-hydroxyquinoline) aluminum based microcavity on device thickness and the emission layer position
In this work, we present a systematic study of the emission from bilayer organic microcavity light emitting diodes with two metal mirrors. The devices consisting of two organic layers, N,NV-di(naphthalene-1-yl)-N,NV-diphenylbenzidine as the hole transport layer and tris (8-hydroxyquinoline) aluminum as the emitting layer, and two metal mirrors were fabricated and characterized by transmittance, reflectance, photoluminescence, and electroluminescence measurements. The effects of layer thickness, interface position, and the choice of anode(bottom mirror) were investigated. The transmittance and reflectance spectra were modeled using a transfer matrix model, and the optical functions for all the materials used were determined by spectroscopic ellipsometry. The dependence of the photoluminescence and electroluminescence spectra on the device thickness and interface position is discussed
Design of a multifunctional plga nanoparticulate drug delivery system: Evaluation of its physicochemical properties and anticancer activity to malignant cancer cells
10.1007/s11095-009-9837-yPharmaceutical Research2651162-1171PHRE
Integrin targeted drug and gene delivery
10.1517/17425240903468696Expert Opinion on Drug Delivery72159-17
NEW AND KNOWN beta-THALASSEMIA DETERMINANTS MASKED BY KNOWN AND NEW delta GENE DEFECTS [Hb A(2)-Ramallah OR delta 6(A3)Glu -> Gln, GAG >> CAG]
We report a novel thalassemia determinant found in a Nigerian woman living in the Netherlands, resulting from a 2 bp insertion at codons 9/10 of the beta-globin gene (HBBc.28_29ins TA p. Ser10LeufsX11). The novel defect causes a frameshift with a consequent premature TGA stop codon, located at 11 positions downstream from the mutated codon. The phenotype was typical of a beta-thalassemia (beta-thal), trait with high RBC counts and compensated mild microcytic anemia. However, the Hb A(2) level was reported to be normal due to the presence of the common Hb A(2)' or Hb B2 [delta 16(A13)Gly-->Arg, GGC>CGC] variant that was not taken into account. We also present the opposite but comparable situation found in an a Palestinian man living in the USA. He was a carrier of a common beta-globin gene defect [codon 6 (-A), HBB:c.20delA] in combination with a novel delta-globin gene defect at codon 6 [HBD.c.19G>C, Glu6Gln] that we have named Hb A(2)-Ramallah. In both cases, the provisional diagnosis could have been compromised when based on the measurement of the normal Hb A(2) fraction only.Genetics of disease, diagnosis and treatmen
Evaluation of the long-acting somatostatin analog octreotide in the management of insulinoma in 3 dogs
The porous titanium dioxide network structure with adjustable average pore size were prepared. The different pore sizes were obtained by controlling the titanium precursor concentration. The porous anatase titania network structure with high surface area is thermally stable and uniform over the whole sample area. The use of these structures in organic solar cells yielded considerable improvements in the short circuit currents compared to previous reports on TiO/sub 2//polymer solar cells
Supplementary Material for: Early Diagnosis of Intra-Abdominal Inflammation and Sepsis by Neutrophil CD64 Expression in Newborns
<p><i>Background:</i> Newborn infants with intra-abdominal
inflammation/sepsis often present with nonspecific signs in the early
stages of the disease, but can rapidly develop life-threatening
complications. A reliable ‘early’ biomarker would be invaluable. <i>Objective:</i> To evaluate the effectiveness of neutrophil CD64 as an ‘early’ biomarker of intra-abdominal inflammation/sepsis. <i>Methods:</i>
Blood was collected from newborns with suspected intra-abdominal
pathology for neutrophil CD64 and C-reactive protein (CRP) determination
at the onset of clinical presentation and 24 h later. They were
classified into three groups: intra-abdominal inflammation/sepsis (group
1), extra-abdominal sepsis (group 2) and nonsepsis (group 3).
Between-group comparisons were made by Kruskal-Wallis and χ<sup>2</sup> tests. Receiver-operating characteristic curves and diagnostic utilities for single and combination of tests were determined. <i>Results:</i>
310 infants were recruited (102, 34 and 174 in groups 1, 2 and 3,
respectively). CD64 (conventional cutoff = 6,010 antibody-PE molecules
bound/cell) had substantially better sensitivity (0.81 vs. 0.56) and
negative predictive value (0.90 vs. 0.79) for diagnosing intra-abdominal
sepsis than CRP, at presentation. Pairing CD64 with routine abdominal
radiograph (AXR) substantially increased the sensitivity and negative
predictive value for group 1 to 0.99 and 0.99, respectively. By
adjusting the CD64 cutoff to 12,500 units, a substantial improvement in
specificity could be achieved (0.62 to 0.80) without significantly
compromising sensitivity (0.99 to 0.97). <i>Conclusions:</i> CD64 is a
sensitive and ‘early’ biomarker for diagnosing intra-abdominal
inflammation/sepsis. Intra-abdominal catastrophes, including necrotizing
enterocolitis, intestinal necrosis, perforation and peritonitis can
confidently be excluded using CD64 and AXR early in the course of the
disease.</p