22,268 research outputs found

    Forenames and Surnames in Spain in 2004

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    This paper quantifies the corpus of forenames and surnames in Spain in 2004 using the telephone directory. It describes their frequency patterns, major measurable characteristics, and gives some geographical distributions, international comparisons, and historical explanations. The research presented here is set in a context of a broader study of the quantitative properties of the corpus of personal names in several countries undertaken by Tucker. Amongst the most significant findings are a much more highly skewed distribution towards the most popular surnames than in other countries, the permanence of language regions since the Middle Ages, and important differences in top Hispanic names frequencies between five countries across the Atlantic. It is also suggested that the innovative techniques presented here, combining geographical and statistical analysis of names and their language of origin, opens up enormous possibilities for multidisciplinary work on onomastics

    Conversion of a gastric band into an intraperitoneal port in a patient with optimally debulked stage 3C serous ovarian carcinoma

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    Intraperitoneal (IP) chemotherapy in women with optimally debulked stage 3 ovarian cancer improves overall survival and progression-free survival, and its use has been encouraged in the adjuvant treatment of appropriately selected patients (Armstrong et al., 2006; Jaaback and Johnson, 2006). We describe a case in which a previously inserted adjustable gastric band was converted to an IP chemotherapy port during a laparotomy for advanced ovarian cancer

    Tool repairs tube components in situ

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    Two versions of a portable tool repair the seats of tube fittings and the flared ends of tubing. Each version operates on the principle of lapping to remove imperfections from tube and fitting interfacing surfaces

    Mobile sampler for use in acquiring samples of terrestrial atmospheric gases

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    Samples of terrestrial atmospheric gasses from a free body of such gasses using a device characterized by a plurality of tubular bodies adapted to be mounted in side by side relation on a motorized highway vehicle in mutual parallelism with the axis of the normal path of travel for the vehicles. Each of the bodies is of a cylindrical configuration and has an axial opening at each of its opposite ends through which a linear flow path is defined. A pair of pivotally supported, spring-biased sealing caps is mounted adjacent to the ends of the body and continuously urged into a hermetic sealing relationship. A restraint for securing the caps against spring-urged pivotal displacement, includes a separable, normally tensioned line interconnecting the caps and an operable release mechanism for simultaneously releasing the caps for spring-urged displacement. A hot wire cutter is included for separating the line, whereby samples of air are trapped in the body as the caps are spring-driven to assume an hermetically sealed relation with the openings defined in each of the opposite ends of the body

    Pseudomonas aeruginosa can be detected in a polymicrobial competition model using impedance spectroscopy with a novel biosensor

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    Electrochemical Impedance Spectroscopy (EIS) is a powerful technique that can be used to elicit information about an electrode interface. In this article, we highlight six principal processes by which the presence of microorganisms can affect impedance and show how one of these - the production of electroactive metabolites - changes the impedance signature of culture media containing Pseudomonas aeruginosa. EIS, was used in conjunction with a low cost screen printed carbon sensor to detect the presence of P. aeruginosa when grown in isolation or as part of a polymicrobial infection with Staphylococcus aureus. By comparing the electrode to a starting measurement, we were able to identify an impedance signature characteristic of P. aeruginosa. Furthermore, we are able to show that one of the changes in the impedance signature is due to pyocyanin and associated phenazine compounds. The findings of this study indicate that it might be possible to develop a low cost sensor for the detection of P. aeruginosa in important point of care diagnostic applications. In particular, we suggest that a development of the device described here could be used in a polymicrobial clinical sample such as sputum from a CF patient to detect P. aeruginosa

    Keck Spectroscopy of Faint 3 < z < 7 Lyman Break Galaxies: III. The Mean Ultraviolet Spectrum at z=4

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    We present and discuss the mean rest-frame ultraviolet spectrum for a sample of 81 Lyman Break Galaxies (LBGs) selected to be B-band dropouts with a mean redshift of z=3.9 and apparent magnitudes z_AB<26. Most of the individual spectra are drawn from our ongoing survey in the GOODS fields with the Keck DEIMOS spectrograph, and we have augmented our sample with published data taken with FORS2 on the VLT. In general we find similar trends in the spectral diagnostics to those found in the earlier, more extensive survey of LBGs at z=3 undertaken by Shapley et al (2003). Specifically, we find low-ionization absorption lines which trace the presence of neutral outflowing gas are weaker in galaxies with stronger Lyman-alpha emission, bluer UV spectral slopes, lower stellar masses, lower UV luminosities and smaller half-light radii. This is consistent with a physical picture whereby star formation drives outflows of neutral gas which scatters Lyman-alpha and gives rise to strong low-ionization absorption lines, while increasing the stellar mass, size, metallicity, and dust content of galaxies. Typical galaxies are thus expected to have stronger Lyman-alpha emission and weaker low-ionization absorption at earlier times (higher redshifts). Indeed, our mean spectrum at z=4 shows somewhat weaker low-ionization absorption lines than at z=3 and available data at higher redshift indicates a rapid decrease in low-ionization absorption strength with redshift. We argue that the reduced low-ionization absorption is likely caused by a decrease in the covering fraction and/or velocity range of outflowing neutral gas at earlier epochs. Our continuing survey will enable us to extend these diagnostics more reliably to higher redshift and determine the implications for the escape fraction of ionizing photons which governs the role of early galaxies in cosmic reionization. [Abridged]Comment: 17 pages, 12 figures, submitted to ApJ. Comments welcom

    The teneurin C-terminal domain possesses nuclease activity and is apoptogenic.

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    Teneurins are type 2 transmembrane proteins expressed by developing neurons during periods of synaptogenesis and apoptosis. Neurons expressing teneurin-1 synapse with other teneurin-1-expressing neurons, and neurons expressing teneurin-2 synapse with other teneurin-2-expressing neurons. Knockdowns and mutations of teneurins lead to abnormal neuronal connections, but the mechanisms underlying teneurin action remain unknown. Teneurins appear to have evolved via horizontal gene transfer from prokaryotic proteins involved in bacterial self-recognition. The bacterial teneurin-like proteins contain a cytotoxic C-terminal domain that is encapsulated in a tyrosine-aspartic acid repeat barrel. Teneurins are likely to be organized in the same way, but it is unclear if the C-terminal domains of teneurins have cytotoxic properties. Here we show that expression of teneurin C-terminal domains or the addition of purified teneurin C-terminal domains leads to an increase in apoptosis in vitro The C-terminal domains of teneurins are most similar to bacterial nucleases, and purified C-terminal domains of teneurins linearize pcDNA3 and hydrolyze mitochondrial DNA. We hypothesize that yet to be identified stimuli lead to the release of the encapsulated teneurin C-terminal domain into the intersynaptic region, resulting in programmed cell death or the disruption of mitochondrial DNA and the subsequent pruning of inappropriate contacts

    The Dynamical Mordell-Lang problem

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    Let X be a Noetherian space, let f be a continuous self-map on X, let Y be a closed subset of X, and let x be a point on X. We show that the set S consisting of all nonnegative integers n such that f^n(x) is in Y is a union of at most finitely many arithmetic progressions along with a set of Banach density zero. In particular, we obtain that given any quasi-projective variety X, any rational self-map map f on X, any subvariety Y of X, and any point x in X whose orbit under f is in the domain of definition for f, the set S is a finite union of arithmetic progressions together with a set of Banach density zero. We prove a similar result for the backward orbit of a point
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