SearchCal: a Virtual Observatory tool for searching calibrators in optical long baseline interferometry. I: The bright object case

In long baseline interferometry, the raw fringe contrast must be calibrated to obtain the true visibility and then those observables that can be interpreted in terms of astrophysical parameters. The selection of suitable calibration stars is crucial for obtaining the ultimate precision of interferometric instruments like the VLTI. We have developed software SearchCal that builds an evolutive catalog of stars suitable as calibrators within any given user-defined angular distance and magnitude around the scientific target. We present the first version of SearchCal dedicated to the bright-object case V<=10; K<=5). Star catalogs available at the CDS are consulted via web requests. They provide all the useful information for selecting of calibrators. Missing photometries are computed with an accuracy of 0.1 mag and the missing angular diameters are calculated with a precision better than 10%. For each star the squared visibility is computed by taking the wavelength and the maximum baseline of the foreseen observation into account.} SearchCal is integrated into ASPRO, the interferometric observing preparation software developed by the JMMC, available at the address: http://mariotti.fr

Magnetism, rotation and accretion in Herbig Ae-Be stars

Studies of stellar magnetism at the pre-main sequence phase can provide important new insights into the detailed physics of the late stages of star formation, and into the observed properties of main sequence stars. This is especially true at intermediate stellar masses, where magnetic fields are strong and globally organised, and therefore most amenable to direct study. This talk reviews recent high-precision ESPaDOnS observations of pre-main sequence Herbig Ae-Be stars, which are yielding qualitatively new information about intermediate-mass stars: the origin and evolution of their magnetic fields, the role of magnetic fields in generating their spectroscopic activity and in mediating accretion in their late formative stages, and the factors influencing their rotational angular momentum.Comment: 8 page

Far-Ultraviolet Dust Albedo Measurements in the Upper Scorpius Cloud Using the SPINR Sounding Rocket Experiment

The Spectrograph for Photometric Imaging with Numeric Reconstruction (SPINR) sounding rocket experiment was launched on 2000 August 4 to record far-ultraviolet (912-1450 A) spectral and spatial information for the giant reflection nebula in the Upper Scorpius region. The data were divided into three arbitrary bandpasses (912-1029 A, 1030-1200 A, and 1235-1450 A) for which stellar and nebular flux levels were derived. These flux measurements were used to constrain a radiative transfer model and to determine the dust albedo for the Upper Scorpius region. The resulting albedos were 0.28+/-0.07 for the 912-1029 A bandpass, 0.33+/-0.07 for the 1030-1200 A bandpass, and 0.77+/-0.13 for the 1235-1450 A bandpass

Candidate X-ray-Emitting OB Stars in the Carina Nebula Identified Via Infrared Spectral Energy Distributions

We report the results of a new survey of massive, OB stars throughout the Carina Nebula using the X-ray point source catalog provided by the Chandra Carina Complex Project (CCCP) in conjunction with infrared (IR) photometry from the Two Micron All-Sky Survey and the Spitzer Space Telescope Vela--Carina survey. Mid-IR photometry is relatively unaffected by extinction, hence it provides strong constraints on the luminosities of OB stars, assuming that their association with the Carina Nebula, and hence their distance, is confirmed. We fit model stellar atmospheres to the optical (UBV) and IR spectral energy distributions (SEDs) of 182 OB stars with known spectral types and measure the bolometric luminosity and extinction for each star. We find that the extinction law measured toward the OB stars has two components: Av=1--1.5 mag produced by foreground dust with a ratio of total-to-selective absorption Rv=3.1 plus a contribution from local dust with Rv>4.0 in the Carina molecular clouds that increases as Av increases. Using X-ray emission as a strong indicator of association with Carina, we identify 94 candidate OB stars with Lbol\geq10^4 Lsun by fitting their IR SEDs. If the candidate OB stars are eventually confirmed by follow-up spectroscopic observations, the number of cataloged OB stars in the Carina Nebula will increase by ~50%. Correcting for incompleteness due to OB stars falling below the Lbol cutoff or the CCCP detection limit, these results potentially double the size of the young massive stellar population.Comment: 19 pages, 8 figures, accepted for the ApJS Special Issue on the Chandra Carina Complex Project (CCCP), scheduled for publication in May 2011. All 16 CCCP Special Issue papers, including a version of this article with high-quality figures, are available at http://cochise.astro.psu.edu/Carina_public/special_issue.html (through 2011 at least

A Photometric Catalogue of Southern Emission-Line Stars

We present a catalogue of previously unpublished optical and infrared photometry for a sample of 162 emission-line objects and shell stars visible from the southern hemisphere. The data were obtained between 1978 and 1997 in the Walraven (WULBV), Johnson/Cousins (UBV(RI)_c) and ESO and SAAO near-infrared (JHKLM) photometric systems. Most of the observed objects are Herbig Ae/Be (HAeBe) stars or HAeBe candidates appearing in the list of HAeBe candidates of Th\'e et al. (1994), although several B[e] stars, LBVs and T Tauri are also included in our sample. For many of the stars the data presented here are the first photo-electric measurements in the literature. The resulting catalogue consists of 1809 photometric measurements. Optical variability was detected in 66 out of the 116 sources that were observed more than once. 15 out of the 50 stars observed multiple times in the infrared showed variability at 2.2 microns (K band).Comment: 42 pages, no figures, to appear in Astronomy & Astrophysic

Cytoplasmic PML promotes TGF-β-associated epithelial–mesenchymal transition and invasion in prostate cancer

Epithelial–mesenchymal transition (EMT) is a key event that is involved in the invasion and dissemination of cancer cells. Although typically considered as having tumour-suppressive properties, transforming growth factor (TGF)-β signalling is altered during cancer and has been associated with the invasion of cancer cells and metastasis. In this study, we report a previously unknown role for the cytoplasmic promyelocytic leukaemia (cPML) tumour suppressor in TGF-β signalling-induced regulation of prostate cancer-associated EMT and invasion. We demonstrate that cPML promotes a mesenchymal phenotype and increases the invasiveness of prostate cancer cells. This event is associated with activation of TGF-β canonical signalling pathway through the induction of Sma and Mad related family 2 and 3 (SMAD2 and SMAD3) phosphorylation. Furthermore, the cytoplasmic localization of promyelocytic leukaemia (PML) is mediated by its nuclear export in a chromosomal maintenance 1 (CRM1)-dependent manner. This was clinically tested in prostate cancer tissue and shown that cytoplasmic PML and CRM1 co-expression correlates with reduced disease-specific survival. In summary, we provide evidence of dysfunctional TGF-β signalling occurring at an early stage in prostate cancer. We show that this disease pathway is mediated by cPML and CRM1 and results in a more aggressive cancer cell phenotype. We propose that the targeting of this pathway could be therapeutically exploited for clinical benefit

Low-resolution spectroscopy and spectral energy distributions of selected sources towards sigma Orionis

Aims: We investigated in detail nine sources in the direction of the young sigma Orionis cluster, which is considered a unique site for studying stellar and substellar formation. The nine sources were selected because of some peculiar properties, such as extremely red infrared colours or too strong Halpha emission for their blue optical colours. Methods: We took high-quality, low-resolution spectroscopy (R ~ 500) of the nine targets with ALFOSC at the Nordic Optical Telescope. We also re-analyzed [24]-band photometry from MIPS/Spitzer and compiled the best photometry available at the ViJHKs passbands and the four IRAC/Spitzer channels for constructing accurate spectral energy distributions covering from 0.55 to 24 mum. Results: The nine targets were classified into: one Herbig Ae/Be star with a scatterer edge-on disc, two G-type stars, one X-ray flaring, early-M, young star with chromospheric Halpha emission, one very low-mass, accreting, young spectroscopic binary, two young objects at the brown dwarf boundary with the characteristics of classical T Tauri stars, and two emission-line galaxies, one undergoing star formation, and another one whose spectral energy distribution is dominated by an active galactic nucleus. Besides, we discover three infrared sources associated to overdensities in a cold cloud in the cluster centre. Conclusions: Low-resolution spectroscopy and spectral energy distributions are a vital tool for measuring the physical properties and the evolution of young stars and candidates in the sigma Orionis cluster.Comment: Accepted for publication in A&