An innovative data mining procedure, using clean algorithm and factor analysis, for irregularly sampled temporal environmental data sets

Οι περιβαλλοντικές βάσεις δεδομένων συχνά αντιμετωπίζουν τα προβλήματα της άτακτης δειγματοληψίας στον χρόνο και της έλλειψης μετρήσεων για κάποιες περιόδους. Το γεγονός αυτό εμποδίζει τη χρήση των κλασικών μεθόδων ανάλυσης χρονοσειρών, οι οποίες απαιτούν σταθερό χρονικό βήμα ενώ ταυτόχρονα τα χρονικά κενά εισάγουν δυσκολίες στην χρήση των περισσοτέρων μεθόδων πολυδιάστατης σταπστικής ανάλυσης. Η παρούσα εργασία προτείνει ένα πλήρες μεθοδολογικό σχήμα ανάλυσης χρονικών περιβαλλονπκών δεδομένων με δειγματοληπτική ανομοιογένεια, στο οποίο γίνεται χρήση του αλγορίθμου CLEAN και της Παραγοντικής ανάλυσης (Factor Analysis). Ο αλγόριθμος CLEAN έχει την ικανότητα να αναπλάθει τις αρχικές χρονοσειρές της βάσης δεδομένων χρησιμοποιώντας φασματική ανάλυση και να δημιουργεί καινούργιες με σταθερό χρονικό βήμα και έλλειψη κενών. Λαμβάνει χώρα δηλαδή τόσο συμπλήρωση των κενών τ?/ς βάσης, όσο και «εξυγίανση» της δειγματοληψίας της. Η παραγοντική ανάλυση ομαδοποιεί τις μεταβλητές, ανάλογα με τον περιβαλλοντικό μηχανισμό από τον οποίο κάθε μια ελέγχεται και επιπλέον αποκαλύπτει τη χαρακτηριστική χρονική διακύμανση της κάθε ομάδας. Το συγκεκριμένο μεθοδολογικό σχήμα εφαρμόστηκε με πλήρη επιτυχία σε μια βάση υδροχημικών δεδομένων μεγάλης χρονικής περιόδου (1980-94) στον ποταμό ΣτρυμόναEnvironmental data are often irregularly collected in the time domain due to various reasons which affect the field sampling schedule. As a result, data sets with uneven time step and time periods with no measurements are frequently built. Many problems occur in such data sets when processed owing to that neither statistical nor spectral analysis methods can easily be applied to them without any specific pre-treatment. In our study it is demonstrated a unified methodological scheme especially designed to deal with incomplete and unevenly sampled temporal data sets. This method consists of the CLEAN algorithm and the Factor analysis. The proposed methodology is successfully applied to data sets that belong to two sampling sites of the Greek river Strimona

Monitoring of a methane-seeping pockmark by cabled benthic observatory (Patras Gulf, Greece)

A new seafloor observatory, the gas monitoring module (GMM), has been developed for continuous and long-term measurements of methane and hydrogen sulphide concentrations in seawater, integrated with temperature (T), pressure (P) and conductivity data at the seafloor. GMM was deployed in April 2004 within an active gas-bearing pockmark in the Gulf of Patras (Greece), at a water depth of 42 m. Through a submarine cable linked to an onshore station, it was possible to remotely check, via direct phone connection, GMM functioning and to receive data in nearreal time. Recordings were carried out in two consecutive campaigns over the periods April–July 2004, and September 2004–January 2005, amounting to a combined dataset of ca. 6.5 months. This represents the first long-term monitoring ever done on gas leakage from pockmarks by means of CH4+H2S+T+P sensors. The results show frequent T and P drops associated with gas peaks, more than 60 events in 6.5 months, likely due to intermittent, pulsation-like seepage. Decreases in temperature in the order of 0.1–1°C (up to 1.7°C) below an ambient T of ca. 17°C (annual average) were associated with short-lived pulses (10–60 min) of increased CH4+H2S concentrations. This seepage “pulsation” can either be an active process driven by pressure build-up in the pockmark sediments, or a passive fluid release due to hydrostatic pressure drops induced by bottom currents cascading into the pockmark depression. Redundancy and comparison of data from different sensors were fundamental to interpret subtle proxy signals of temperature and pressure which would not be understood using only one sensor.Published297-302JCR Journalreserve

Air transport liberalisation and airport dependency: developing a composite index

Air transport liberalisation in Europe has produced some major changes to the networks operated by airlines and the services available at airports. Within this context the degree of airport dependency in terms of market, spatial and temporal concentration is important to know from an economic geography and risk management perspective. A composite index called the Airport Dependency Index (ADI) is developed to measure airport dependency based on the concept of the relative Gini coefficient. Liberalisation has had varying impacts depending on the size and type of airport and so a comparison is made of the degree of dependency at a large sample of European airports using the ADI. The ADI has the potential to provide insight on the sustainability and worthiness of financing airport projects, and on whether airports should diversify further their activities by investing in the growth and expansion of their network

Measuring co-authorship and networking-adjusted scientific impact

Appraisal of the scientific impact of researchers, teams and institutions with productivity and citation metrics has major repercussions. Funding and promotion of individuals and survival of teams and institutions depend on publications and citations. In this competitive environment, the number of authors per paper is increasing and apparently some co-authors don't satisfy authorship criteria. Listing of individual contributions is still sporadic and also open to manipulation. Metrics are needed to measure the networking intensity for a single scientist or group of scientists accounting for patterns of co-authorship. Here, I define I1 for a single scientist as the number of authors who appear in at least I1 papers of the specific scientist. For a group of scientists or institution, In is defined as the number of authors who appear in at least In papers that bear the affiliation of the group or institution. I1 depends on the number of papers authored Np. The power exponent R of the relationship between I1 and Np categorizes scientists as solitary (R>2.5), nuclear (R=2.25-2.5), networked (R=2-2.25), extensively networked (R=1.75-2) or collaborators (R<1.75). R may be used to adjust for co-authorship networking the citation impact of a scientist. In similarly provides a simple measure of the effective networking size to adjust the citation impact of groups or institutions. Empirical data are provided for single scientists and institutions for the proposed metrics. Cautious adoption of adjustments for co-authorship and networking in scientific appraisals may offer incentives for more accountable co-authorship behaviour in published articles.Comment: 25 pages, 5 figure

Acute administration of the olive constituent, oleuropein, combined with ischemic postconditioning increases myocardial protection by modulating oxidative defense

Oleuropein, one of the main polyphenolic constituents of olive, is cardioprotective against ischemia reperfusion injury (IRI). We aimed to assess the cardioprotection afforded by acute administration of oleuropein and to evaluate the underlying mechanism. Importantly, since antioxidant therapies have yielded inconclusive results in attenuating IRI-induced damage on top of conditioning strategies, we investigated whether oleuropein could enhance or imbed the cardioprotective manifestation of ischemic postconditioning (PostC). Oleuropein, given during ischemia as a single intravenous bolus dose reduced the infarct size compared to the control group both in rabbits and mice subjected to myocardial IRI. None of the inhibitors of the cardioprotective pathways, l-NAME, wortmannin and AG490, influence its infarct size limiting effects. Combined oleuropein and PostC cause further limitation of infarct size in comparison with PostC alone in both animal models. Oleuropein did not inhibit the calcium induced mitochondrial permeability transition pore opening in isolated mitochondria and did not increase cGMP production. To provide further insights to the different cardioprotective mechanism of oleuropein, we sought to characterize its anti-inflammatory potential in vivo. Oleuropein, PostC and their combination reduce inflammatory monocytes infiltration into the heart and the circulating monocyte cell population. Oleuropein's mechanism of action involves a direct protective effect on cardiomyocytes since it significantly increased their viability following simulated IRI as compared to non-treated cells. Οleuropein confers additive cardioprotection on top of PostC, via increasing the expression of the transcription factor Nrf-2 and its downstream targets in vivo. In conclusion, acute oleuropein administration during ischemia in combination with PostC provides robust and synergistic cardioprotection in experimental models of IRI by inducing antioxidant defense genes through Nrf-2 axis and independently of the classic cardioprotective signaling pathways (RISK, cGMP/PKG, SAFE)

ARIADNE: A Research Infrastructure for Archaeology

Research e-infrastructures, digital archives, and data services have become important pillars of scientific enterprise that in recent decades have become ever more collaborative, distributed, and data intensive. The archaeological research community has been an early adopter of digital tools for data acquisition, organization, analysis, and presentation of research results of individual projects. However, the provision of e-infrastructure and services for data sharing, discovery, access, and (re)use have lagged behind. This situation is being addressed by ARIADNE, the Advanced Research Infrastructure for Archaeological Dataset Networking in Europe. This EU-funded network has developed an e-infrastructure that enables data providers to register and provide access to their resources (datasets, collections) through the ARIADNE data portal, facilitating discovery, access, and other services across the integrated resources. This article describes the current landscape of data repositories and services for archaeologists in Europe, and the issues that make interoperability between them difficult to realize. The results of the ARIADNE surveys on users’ expectations and requirements are also presented. The main section of the article describes the architecture of the e-infrastructure, core services (data registration, discovery, and access), and various other extant or experimental services. The ongoing evaluation of the data integration and services is also discussed. Finally, the article summarizes lessons learned and outlines the prospects for the wider engagement of the archaeological research community in the sharing of data through ARIADNE

Dynamic light scattering study on phase separation of a protein-water mixture: Application on cold cataract development in the ocular lens

We present a detailed dynamic light scattering study on the phase separation in the ocular lens emerging during cold cataract development. Cold cataract is a phase separation effect that proceeds via spinodal decomposition of the lens cytoplasm with cooling. Intensity auto-correlation functions of the lens protein content are analyzed with the aid of two methods providing information on the populations and dynamics of the scattering elements associated with cold cataract. It is found that the temperature dependence of many measurable parameters changes appreciably at the characteristic temperature ~16+1 oC which is associated with the onset of cold cataract. Extending the temperature range of this work to previously inaccessible regimes, i.e. well below the phase separation or coexistence curve at Tcc, we have been able to accurately determine the temperature dependence of the collective and self-diffusion coefficient of proteins near the spinodal. The analysis showed that the dynamics of proteins bears some resemblance to the dynamics of structural glasses where the apparent activation energy for particle diffusion increases below Tcc indicating a highly cooperative motion. Application of ideas developed for studying the critical dynamics of binary protein/solvent mixtures, as well as the use of a modified Arrhenius equation, enabled us to estimate the spinodal temperature Tsp of the lens nucleus. The applicability of dynamic light scattering as a non-invasive, early-diagnostic tool for ocular diseases is also demonstrated in the light of the findings of the present paper